Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium

American Journal of Pathology

Volumn 154, Issue 1, 1999, Pages 29-35

  Barker, Nick ^a   Huls, Gerwin ^a   Korinek, Vladimir ^b   Clevers, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; TRANSCRIPTION FACTOR;

ARTICLE; BREAST EPITHELIUM; CARCINOGENESIS; CELL CULTURE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

EID: 0032921038     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65247-9     Document Type: Article

References (20)

1. Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destree O, Clevers H: Xtcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell 1996, 86:391-399
2. Riese J, Yu X, Munnerlyn A, Eresh S, Hsu SC, Grosschedl R, Bienz M: LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell 1997, 88:777-787
3. Brunner E, Peter O, Schweizer L, Basler K: Pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 1997, 385:829-833
4. van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, Loureiro A, Ypma D, Hursh D, Jones T, Bejsovec A, Peifer M, Mortin M, Clevers H: Armadillo co-activates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 1997, 88:789-799
5. Behrens J, van Kries JP, Kuehl M, Bruhn D, Wedlich R, Grosschedl R, Birchmeier W: Functional interaction of β-catenin with the transcription factor LEF-1. Nature 1996, 382:638-642
6. Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG, Kemler R: Nuclear translocation of β-catenin by interaction with transcription factor LEF-1. Mech Dev 1996, 59:3-10
7. Clevers H, van de Wetering, M: TCF/LEF factors earn their wings. Trends Genet 1997, 13:485-489
8. Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H: Two members of the Tcf family implicated in Wnt/β-catenin signaling during embryogenesis in the mouse. Mol Cell Biol 1998, 18:1248-1256
9. MacMahon AP, Bradley A: The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 1990, 62:1073-1085
10. Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H: Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Gen 1998, 19:379-383
11. -/- colon carcinoma. Science 1997, 275:1784-1787
12. Morin PJ, Sparks A, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW: Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 1997, 275:1787-1790
13. Castrop J, van Wichen D, Koomans-Bitter M, van de Wetering M, de Weger R, van Dongen J, Clevers H: The human TCF-1 gene encodes a nuclear DNA-binding protein, uniquely expressed in normal and neoplastic T lineage lymphocytes. Blood 1995, 86:3050-3059
14. Rubinfield B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P: Stabilization of β-catenin by genetic defects in melanoma cell-lines. Science 1997, 275:1790-1792
15. van de Wetering M, Oosterwegel M, Dooijes D, Clevers H: Identification and cloning of TCF-1, a T-cell specific transcription factor containing a sequence-specific HMG box. EMBO J 1991, 10:123-132
16. Travis A, Amsterdam A, Belanger C, Grosschedl R: Lef-1, a gene encoding a lymphoid-specific protein, with an HMG domain, regulates T-cell receptor α enhancer function. Genes Dev 1991, 5:880-894
17. Oosterwegel M, van de Wetering M, Timmerman J, Kruisbeek A, Destree O, Meijlink F, Clevers H: Differential expression of the HMG box factors TCF-1 and LEF-1. Development 1993, 118:439-448
18. Van Genderen V, Okamura RM, Farinas I, Quo RG, Parslow TG, Bruhn L, Grosschedl R: Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1 defcient mice. Genes Dev 1994, 8:2691-2704
19. Schmidt GH, Winton DJ, Ponder BA: Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development 1988, 103:785-790
20. Calvert R, Pothier P: Migration of fetal intestinal intervillous cells in neonatal mice. Anat Rec 1990, 227:199-206