Facilitation of signal onset and termination by adenylyl cyclase

Science

Volumn 283, Issue 5406, 1999, Pages 1328-1331

  Scholich, Klaus ^a   Mullenix, Jason B ^a   Wittpoth, Claus ^a   Poppleton, Helen M ^a   Pierre, Sandra C ^a   Lindorfer, Margaret A ^a   Garrison, James C ^a   Patel, Tarun B ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN G;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 0033605122     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.283.5406.1328     Document Type: Article

References (29)

1. M. R. Koelle and H. R. Horvitz, Cell 84, 115 (1996).
2. D. M. Watson, M. E. Linder, K. M. Druey, J. H. Kehrl, K. J. Blumer. Nature 363, 172 (1996).
3. T. W. Hunt, T. A. Fields, P. J. Casey, E. G. Peralta, ibid., p. 175.
4. K. M. Druey, K. J. Blumer, V. H. Kang, J. H. Kehrl, ibid. 379, 742 (1996).
5. D. M. Berman, T. M. Wilkie, A. G. Gilman, Cell 86, 445 (1996).
6. J. R. Hepler, D. M. Berman, A. G. Gilman, T. Kozasa, Proc. Natl. Acad. Sci. U.S.A. 94, 428 (1997).
7. C. K. Chen, T. Wieland, M. I. Simon, ibid. 93, 12885 (1996).
8. S. P. Heximer, N. Watson, M. E. Linder, K. J. Blumer, J. R. Hepler, ibid. 94, 14389 (1997).
9. R. Iyengar, FASEB J. 7, 768 (1993).
10. R. K. Sunahara, C. W. Dessauer, A. G. Gilman, Annu. Rev. Pharmacol. 36, 461 (1997).
11. K. Scholich, A. J. Barbier, J. B. Mullenix, T. B. Patel, Proc. Natl. Acad. Sci. U.S.A. 94, 2915 (1997).
12. K. Scholich, C. Wittpoth, A. J. Barbier, J. B. Mullenix, T. B. Patel, ibid., p. 9602.
13. 35S, indicating that the stability of the G protein was not altered (15).
14. J. J. G. Tesmer, R. K. Sunahara, A. G. Gilman, S. R. Sprang, Science 278, 1907 (1997).
15. K. Scholich and T. B. Patel, unpublished data.
16. H. Sun, J. M. Seyer, T. B. Patel, Proc. Natl. Acad. Sci. U.S.A. 92, 2229 (1995).
17. T. Okamoto et al., Cell 68, 723 (1991).
18. T. Higashijima, K. M. Ferguson, M. D. Smigel, A. G. Gilman, J. Biol. Chem. 262, 757 (1987).
19. P. C. Sternweis and A. G. Gilman, ibid. 254, 3333 (1979).
20. O. Saitoh, Y. Kubo, Y. Miyatani, T. Asano, H. Nakata, Nature 390, 525 (1997); C. A. Doupnik, N. Davidson, H. A. Lester, P. Kofuji, Proc. Natl. Acad. Sci. U.S.A. 94, 10461 (1997).
21. O. Saitoh, Y. Kubo, Y. Miyatani, T. Asano, H. Nakata, Nature 390, 525 (1997); C. A. Doupnik, N. Davidson, H. A. Lester, P. Kofuji, Proc. Natl. Acad. Sci. U.S.A. 94, 10461 (1997).
22. G. Bernstein et al., Cell 70, 411 (1992).
23. V. Y. Arshkavsky and M. D. Bownds, Nature 357, 416 (1992).
24. M. P. Graziano, M. Freissmuth, A. G. Gilman, Methods Enzymol. 195, 192 (1991).
25. R. E. Whisnant, A. G. Gilman, C. W. Dessauer, Proc. Natl. Acad. Sci. U.S.A. 93, 6621 (1996).
26. S. G. Graber, R. A Figler, J. C. Garrison, Methods Enzymol. 237, 212 (1994).
27. E. J. Neer, J. M. Lok, L. G. Wolf, J. Biol. Chem. 259, 14222 (1984); S. Mumby, I.-H. Pang, A. G. Gilman, P. C. Sternweis, ibid. 263, 2020 (1988).
28. E. J. Neer, J. M. Lok, L. G. Wolf, J. Biol. Chem. 259, 14222 (1984); S. Mumby, I.-H. Pang, A. G. Gilman, P. C. Sternweis, ibid. 263, 2020 (1988).
29. sα cDNA, and Y. Ishikawa for the canine ACV cDNA. Supported by NIH grants HL48308 (T.B.P.) and HL59679 (T.B.P.) and an American Heart Association, TN Affiliate postdoctoral fellowship (to K.S.). This report is dedicated to the memory of Dr. Martin Rodbell.