Analysis of events leading to neuronal death after infection with E1- deficient adenoviral vectors

Molecular and Cellular Neurosciences

Volumn 11, Issue 5-6, 1998, Pages 334-347

  Easton, Rachael M ^a   Johnson Jr , Eugene M ^a   Creedon, Douglas J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CYTOTOXICITY; EMBRYO; GENE EXPRESSION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS INFECTION; VIRUS RECOMBINANT; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALIA;

EID: 0031865046     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1998.0690     Document Type: Article

References (51)

1. Adams P. D., Kaelin W. G. Jr. The cellular effects of E2F overexpression. Curr. Top. Microbiol. Immunol. 208:1996;79-93.
2. Becker T. C., Noel R. J., Coats W. S., Gomez-Foix A. M., Alam T., Gerard R. D., Newgard C. B. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol. 43:1994;161-189.
3. Bello L. J., Ginsberg H. S. Inhibition of host protein synthesis in type 5 adenovirus-infected cells. J. Virol. 1:1976;843-850.
4. Beltz G. A., Flint S. J. Inhibition of HeLa cell protein synthesis during adenovirus infection. J. Mol. Biol. 131:1979;353-373.
5. Bett A. J., Krougliak V., Graham F. L. DNA sequence of the deletion/insertion in early region 3 of Ad5dl. Virus Res. 39:1995;75-82.
6. Caillaud C., Akli S., Vigne E., Koulakoff A., Perricaudet M., Poenaru L., Kahn A., Berwald-Netter Y. Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells. Eur. J. Neurosci. 5:1993;1287-1291.
7. Castel-Barthe M. N., Jazat-Poindessous F., Barneoud P., Vigne E., Revah F., Mallet J., Lamour Y. Direct intracerebral nerve growth factor gene transfer using a recombinant adenovirus: Effect on basal forebrain cholinergic neurons during aging. Neurobiol. Dis. 3:1996;76-86.
8. Choi-Lundberg D. L., Lin Q., Chang Y.-N., Chiang Y. L., Hay C. M., Mohajeri H., Davidson B. L., Bohn M. C. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science. 275:1997;838-841.
9. Chun L. L.Y., Patterson P. H. Role of nerve growth factor in the development of rat sympathetic neuronsin vitro. J. Cell Biol. 75:1977;705-711.
10. Cress W. D., Nevins J. R. Use of the E2F transcription factor by DNA tumor virus regulatory proteins. Curr. Top. Microbiol. Immunol. 208:1996;63-78.
11. Davidson B. L., Bohn M. C. Recombinant adenovirus: A gene transfer vector for study and treatment of CNS diseases. Exp. Neurol. 144:1997;125-130.
12. Davidson B. L., Doran S. E., Shewach D. S., Latta J. M., Hartman J. W., Roessler B. J. Expression ofEscherichia coliMacaca mulatta. Exp. Neurol. 125:1994;258-267.
13. Deckwerth T. L., Johnson E. M. Jr. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123:1993;1207-1222.
14. Durham H. D., Lochmuller H., Jani A., Acsadi G., Massie B., Karpati G. Toxicity of replication-defective recombinants in dissociated cultures of nervous tissue. Exp. Neurol. 140:1996;14-20.
15. Easton R. M., Deckwerth T. L., Parsadanian A. Sh., Johnson E. M. Jr. Analysis of the mechanism of the loss of trophic factor dependence associated with neuronal maturation: A phenotype indistinguishable fromBax. J. Neurosci. 17:1997;9656-9666.
16. Estus S. Optimization and validation of RT-PCR as a tool to analyze apoptotic gene expression. Neuromethods: Apoptosis Techniques and Protocols. 1997;Humana Press, Totowa. p. 67-84.
17. Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R., Johnson E. M. Jr. Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127:1994;1717-1727.
18. Farinelli S. E., Greene L. A. Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support. J. Neurosci. 16:1996;1150-1162.
19. Freeman R. S., Estus S., Johnson E. M. Jr. Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death. Neuron. 12:1994;343-355.
20. Goldman M. J., Litzky L. A., Engelhardt J. F., Wilson J. M. Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: A preclinical toxicology study. Hum. Gene Ther. 6:1995;839-851.
21. Gorziglia M. I., Kadan M. J., Yei S., Lim J., Lee G. M., Luthra R., Trapnell B. C. Elimination of both E1 and E2 from adenovirus vectors further improves prospects forin vivo. J. Virol. 70:1996;4173-4178.
22. Graham F. L., Prevec L. Manipulation of adenovirus vectors. Murray E. J. Methods in Molecular Biology. 1991;109-128 Humana Press, Clifton.
23. Heintz N. Cell death and the cell cycle: A relationship between transformation and neurodegeneration. Trends Biochem. Sci. 18:1993;157-159.
24. Horellou P., Sabate O., Buc-Caron M.-H., Mallet J. Adenovirus-mediated gene transfer to the central nervous system for Parkinson's disease. Exp. Neurol. 144:1997;131-138.
25. Johnson M. I., Argiro V. Techniques in the tissue culture of rat sympathetic neurons. Methods Enzymol. 103:1983;334-347.
26. Kao H., Nevins J. R. Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection. Mol. Cell. Biol. 3:1983;2058-2065.
27. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270:1995;16483-16486.
28. Karin M., Hunter T. Transcriptional control by protein phosphorylation: Signal transduction from cell surface to the nucleus. Curr. Biol. 5:1995;747-757.
29. Klessig D. F., Brough D. E., Cleghon V. Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell. Mol. Cell. Biol. 4:1984;1354-1362.
30. Lazarus K. J., Bradshaw R. A., West N. R., Bunge P. Adaptive survival of rat sympathetic neurons cultured without supporting cells or exogenous nerve growth factor. Brain Res. 113:1976;159-164.
31. Leber S. M., Yamagata M., Sanes J. R. Gene transfer using replication-defective retroviral and adenoviral vectors. Methods Cell Biol. 51:1996;161-183.
32. Le Gal La Salle G., Robert J. J., Berrard S., Ridoux V., Stratford-Perricaudet L. D., Perricaudet M., Mallet J. An adenovirus vector for gene transfer into neurons and glia in the brain. Science. 259:1993;988-990.
33. Lieber A., He C.-Y., Kirillova I., Kay M. A. Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J. Virol. 70:1996;8944-8960.
34. Lisovoski F., Cadusseau J., Akli S., Caillaud C., Vigne E., Poenaru L., Stratford-Perricaudet L., Perricaudet M., Kahn A., Peschanski M. In vivo. Neuroreport. 5:1994;1069-1072.
35. Martin D. P., Schmidt R. E., DiStefano P. S., Lowry O. H., Carter J. G., Johnson E. M. Jr. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol. 106:1988;829-844.
36. Moriyoshi K., Richards L. J., Akazawa C., O'Leary D. D. M., Nakanishi S. Labeling neuronal cells using adenoviral gene transfer of membrane-targeted GFP. Neuron. 16:1996;255-260.
37. Nevins J. R. Mechanism of activation of early viral transcription by adenovirus E1A gene product. Cell. 26:1981;213-220.
38. Nevins J. R. Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell. 29:1982;913-919.
39. Peltekian E., Parrish E., Bouchard C., Peschanski M., Lisovosi F. Adenovirus-mediated gene transfer to the brain: Methodological assessment. J. Neurosci. Methods. 71:1997;77-84.
40. Rich D. P., Couture L. A., Cardoza L. M., Guiggio V. M., Armentano D., Espino P. C., Hehir K., Welsh M. J., Smith A. E., Gregory R. J. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum. Gene Ther. 4:1993;461-476.
41. Robert J.-J., Geoffroy M.-C., Finiels F., Mallet J. An adenoviral vector-based system to study neuronal gene expression: Analysis of the rat tyrosine hydroxylase promoter in cultured neurons. J. Neurochem. 68:1997;2152-2160.
42. Shenk T., Flint J. Transcriptional and transforming activities of the adenovirus E1A proteins. Adv. Cancer Res. 57:1991;47-85.
43. Slack R. S., Belliveau D. J., Rosenberg M., Atwal J., Lochmuller H., Aloyz R., Haghighi A., Lach B., Seth P., Cooper E., Miller F. D. Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons. J. Cell Biol. 135:1996;1085-1096.
44. Teramoto S., Johnson L. G., Huang W., Leigh M. W., Boucher R. C. Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells. Hum. Gene Ther. 6:1995;1045-1053.
45. Thoenen H., Tranzer J. P. Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine. Naunyn Schmiedebergs Arch. Pharm. 261:1968;271-288.
46. Tranzer J. P., Thoenen H. An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia. 24:1968;155-156.
47. Tranzer J. P., Thoenen H., Snipes R. L., Richards J. G. Recent developments on the ultrastructural aspect of adrenergic nerve endings in various experimental conditions. Prog. Brain Res. 31:1969;33-46.
48. Ucker D. S. Death by suicide: One way to go in mammalian cellular development. New Biol. 3:1991;103-109.
49. Wang Q., Finer M. H. Second-generation adenovirus vectors. Nat. Med. 2:1996;714-716.
50. Yang Y., Nunes F., Berencsi K., Furth E. E., Gonczol E., Wilson J. M. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA. 91:1994a;4407-4411.
51. Yang Y., Nunes F. A., Berencsi K., Gonczol E., Engelhardt J. F., Wilson J. M. Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. Nat. Genet. 7:1994b;362-369.