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Volumn 21, Issue 4, 1997, Pages 469-475

Reversal of parkinsonian symptoms in primates by antagonism of excitatory amino acid transmission: Potential mechanisms of action

Author keywords

(R) HA 966; Excitatory amino acid; Globus pallidus; Glutamate; Glycine; Kappa opiate; NMDA; Parkinsonism; Polyamine ifenprodil; Primate; Striatum

Indexed keywords

3 AMINO 1 HYDROXY 2 PYRROLIDINONE; AMINO ACID RECEPTOR BLOCKING AGENT; IFENPRODIL; KAPPA OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0030990697     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(96)00036-X     Document Type: Article
Times cited : (39)

References (63)
  • 1
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • 1. Albin, R. L.; Young, A. B.; Penney, J. B., The functional anatomy of basal ganglia disorders. Trends in Neurosciences, 12, 366-375 1989.
    • (1989) Trends in Neurosciences , vol.12 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 2
    • 0024397504 scopus 로고
    • Cellular localisation of enkephalin gene expression in MPTP-treated cynomologous monkeys
    • 2. Augood, S. J.; Emson, P. C. et al., Cellular localisation of enkephalin gene expression in MPTP-treated cynomologous monkeys. Molecular Brain Research, 6, 85-92 1989.
    • (1989) Molecular Brain Research , vol.6 , pp. 85-92
    • Augood, S.J.1    Emson, P.C.2
  • 3
    • 0027479766 scopus 로고
    • Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys
    • 3. Benazzouz, A.; Gross, C.; Feger, J.; Boraud, T.; Biolac, B., Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys. Eur. J. Pharmacol., 5, 382-389 1993.
    • (1993) Eur. J. Pharmacol. , vol.5 , pp. 382-389
    • Benazzouz, A.1    Gross, C.2    Feger, J.3    Boraud, T.4    Biolac, B.5
  • 4
    • 0025169590 scopus 로고
    • Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
    • 4. Bergman, H.; Wichmann, T.; Delong, M. R., Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science, 249, 1436-1438 1990.
    • (1990) Science , vol.249 , pp. 1436-1438
    • Bergman, H.1    Wichmann, T.2    Delong, M.R.3
  • 6
    • 0025845919 scopus 로고
    • Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate
    • 6. Brotchie, J. M.; Mitchell, I. J.; Sambrook, M. A.; Crossman, A. R., Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate. Movement Disoders, 6 (2), 133-138 1991.
    • (1991) Movement Disoders , vol.6 , Issue.2 , pp. 133-138
    • Brotchie, J.M.1    Mitchell, I.J.2    Sambrook, M.A.3    Crossman, A.R.4
  • 7
    • 0001332813 scopus 로고
    • The NR2 subunit contributes to the pharmacological diversity of native NMDA receptors
    • 7. Buller, A. L.; Morrisett, R. A.; Monaghan, D. T. The NR2 subunit contributes to the pharmacological diversity of native NMDA receptors. Soc. Neurosci. Abstr., 19(2): 1356, 557.10; 1993.
    • (1993) Soc. Neurosci. Abstr. , vol.19 , Issue.2 , pp. 1356
    • Buller, A.L.1    Morrisett, R.A.2    Monaghan, D.T.3
  • 8
    • 0024501249 scopus 로고
    • The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice
    • 8. Carlsson, M.; Carlsson, A., The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice. Journal of Neural Transmission, 75, 221-226 1989.
    • (1989) Journal of Neural Transmission , vol.75 , pp. 221-226
    • Carlsson, M.1    Carlsson, A.2
  • 9
    • 0024360965 scopus 로고
    • Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice
    • 9. Carlsson, M.; Carlsson, A., Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice. Journal of Neural Transmission, 77, 65-71 1989.
    • (1989) Journal of Neural Transmission , vol.77 , pp. 65-71
    • Carlsson, M.1    Carlsson, A.2
  • 10
    • 0029044987 scopus 로고
    • Neurochemical and behavioural investigations of the NMDA receptor-associated glycine site in the rat striatum: Functional implications for treatment of parkinsonian symptoms
    • 10. Carroll, C. B.; Holloway, V.; Brotchie, J. M.; Mitchell, I. J., Neurochemical and behavioural investigations of the NMDA receptor-associated glycine site in the rat striatum: functional implications for treatment of parkinsonian symptoms. Psychopharmacology, 119, 55-65 1995.
    • (1995) Psychopharmacology , vol.119 , pp. 55-65
    • Carroll, C.B.1    Holloway, V.2    Brotchie, J.M.3    Mitchell, I.J.4
  • 11
    • 0025162935 scopus 로고
    • Effects of classical and novel agents in a MPTP-induced reversible model of Parkinson's disease
    • 11. Close, S. P.; Elliott, P. J. et al., Effects of classical and novel agents in a MPTP-induced reversible model of Parkinson's disease. Psychopharmacology, 102, 295-300 1990.
    • (1990) Psychopharmacology , vol.102 , pp. 295-300
    • Close, S.P.1    Elliott, P.J.2
  • 12
    • 0023180067 scopus 로고
    • NMDA receptors-their role in long-term potentiation
    • 12. Collingridge, G. L.; Bliss, T. V. P., NMDA receptors-their role in long-term potentiation. Trends in Neurosciences, 10 (7), 288-293 1987.
    • (1987) Trends in Neurosciences , vol.10 , Issue.7 , pp. 288-293
    • Collingridge, G.L.1    Bliss, T.V.P.2
  • 14
    • 0024420232 scopus 로고
    • Effect of the NMDA antagonist MK-801 on MPTP-induced parkinsonism in the monkey
    • 14. Crossman, A. R.; Peggs, D. et al., Effect of the NMDA antagonist MK-801 on MPTP-induced parkinsonism in the monkey. Neuropharmacology, 28 (11), 1271-1273 1989.
    • (1989) Neuropharmacology , vol.28 , Issue.11 , pp. 1271-1273
    • Crossman, A.R.1    Peggs, D.2
  • 15
    • 0027440486 scopus 로고
    • NMDA antagonist and dopamine D-1 and D-2 agonist interactions in MPTP-induced hemiparkinsonian monkeys
    • 15. Domino, E. F.; Sheng, J., NMDA antagonist and dopamine D-1 and D-2 agonist interactions in MPTP-induced hemiparkinsonian monkeys. Journal of Pharmacological and Experimental Therapy, 264, 221-225 1993.
    • (1993) Journal of Pharmacological and Experimental Therapy , vol.264 , pp. 221-225
    • Domino, E.F.1    Sheng, J.2
  • 16
    • 0024318696 scopus 로고
    • HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site
    • 16. Foster, A. C.; Kemp, J. A., HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site. Journal of Neuroscience, 9 (6), 2191-2196 1989.
    • (1989) Journal of Neuroscience , vol.9 , Issue.6 , pp. 2191-2196
    • Foster, A.C.1    Kemp, J.A.2
  • 17
    • 0011185810 scopus 로고
    • Distribution of enkephalin gene expression in the striatum of the parkinsonian primate: Implications for dopamine agonist-induced dystonia
    • 17. Frayne, S. E.; Mitchell, I. J. et al., Distribution of enkephalin gene expression in the striatum of the parkinsonian primate: implications for dopamine agonist-induced dystonia. Molecular Neuropharmacology, 1, 53-58 1991.
    • (1991) Molecular Neuropharmacology , vol.1 , pp. 53-58
    • Frayne, S.E.1    Mitchell, I.J.2
  • 18
    • 0025944714 scopus 로고
    • Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: In situ hybridization histochemical analysis
    • 18. Gerfen, C. R.; McGinty, J. F.; Young, W. S., Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis. Journal of Neuroscience, 11 (4), 1016-1031 1991.
    • (1991) Journal of Neuroscience , vol.11 , Issue.4 , pp. 1016-1031
    • Gerfen, C.R.1    McGinty, J.F.2    Young, W.S.3
  • 19
    • 17144446935 scopus 로고
    • Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism
    • 19. Graham, W. C.; Robertson, R. G.; Sambrook, M. A.; Crossman, A. R. Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism. Life Sciences 47: PL-91-PL-N97; 1990.
    • (1990) Life Sciences , vol.47
    • Graham, W.C.1    Robertson, R.G.2    Sambrook, M.A.3    Crossman, A.R.4
  • 20
    • 0027232162 scopus 로고
    • Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain,as revealed from radioligand binding studies
    • 20. Grimwood, S.; Wilde, G. J. C.; Foster, A. C., Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain,as revealed from radioligand binding studies. Journal of Neurochemistry, 60, 1729-1738 1993.
    • (1993) Journal of Neurochemistry , vol.60 , pp. 1729-1738
    • Grimwood, S.1    Wilde, G.J.C.2    Foster, A.C.3
  • 22
    • 0025004597 scopus 로고
    • Excitatory amino acids in the developing brain: Ontogeny, plasticity, and excitotoxicity
    • 22. Hattori, H.; Wasterlain, C. G., Excitatory amino acids in the developing brain: ontogeny, plasticity, and excitotoxicity. Pediatric Neurology, 6, 219-228 1990.
    • (1990) Pediatric Neurology , vol.6 , pp. 219-228
    • Hattori, H.1    Wasterlain, C.G.2
  • 23
    • 0027410070 scopus 로고
    • Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits
    • 23. Ishii, T.; Moriyoshi, K. et al., Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. Journal of Biological Chemistry, 268 (4), 2836-2842 1993.
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.4 , pp. 2836-2842
    • Ishii, T.1    Moriyoshi, K.2
  • 24
    • 0025044617 scopus 로고
    • Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes
    • 24. Jiang, H.-K.; McGinty, J. F.; Hong, J. S., Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes. Brain Research, 507, 57-64 1990.
    • (1990) Brain Research , vol.507 , pp. 57-64
    • Jiang, H.-K.1    McGinty, J.F.2    Hong, J.S.3
  • 25
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA receptors expressed in Xenopus oocytes
    • 25. Kleckner, N. W.; Dingledine, R., Requirement for glycine in activation of NMDA receptors expressed in Xenopus oocytes. Science, 241, 835-836 1988.
    • (1988) Science , vol.241 , pp. 835-836
    • Kleckner, N.W.1    Dingledine, R.2
  • 26
    • 0026074931 scopus 로고
    • The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys
    • 26. Klockgether, T.; Turski, L. et al., The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys. Annals of Neurology, 30, 717-723 1991.
    • (1991) Annals of Neurology , vol.30 , pp. 717-723
    • Klockgether, T.1    Turski, L.2
  • 28
    • 0026717250 scopus 로고
    • Molecular diversity of the NMDA receptor channel
    • 28. Kutsuwada, T.; Kashiwabuchi, N.; Mori, H. et al., Molecular diversity of the NMDA receptor channel. Nature, 358, 36-41 1992.
    • (1992) Nature , vol.358 , pp. 36-41
    • Kutsuwada, T.1    Kashiwabuchi, N.2    Mori, H.3
  • 29
    • 0026536547 scopus 로고
    • Leksell's poster-oventral pallidotomy in the treatment of Parkinson's disease
    • 29. Laitinen, L. V.; Bergenheim, A. T.; Hariz, M. I., Leksell's poster-oventral pallidotomy in the treatment of Parkinson's disease. Journal of Neurosurgery, 76, 53-61 1992.
    • (1992) Journal of Neurosurgery , vol.76 , pp. 53-61
    • Laitinen, L.V.1    Bergenheim, A.T.2    Hariz, M.I.3
  • 30
    • 0029068332 scopus 로고
    • NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum
    • 30. Landwehrmeyer, G. B.; Standaert, D. G.; Testa, C. M.; Penney, J. B.; Young, A. B. NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. Journal of Neuroscience, 15(7 Pt 2):5297-5307; 1995.
    • (1995) Journal of Neuroscience , vol.15 , Issue.7 PART 2 , pp. 5297-5307
    • Landwehrmeyer, G.B.1    Standaert, D.G.2    Testa, C.M.3    Penney, J.B.4    Young, A.B.5
  • 31
    • 0027253657 scopus 로고
    • The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys
    • 31. Luquin, M. R.; Obeso, J. A. et al., The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys. European Journal of Pharmacology, 235, 297-300 1993.
    • (1993) European Journal of Pharmacology , vol.235 , pp. 297-300
    • Luquin, M.R.1    Obeso, J.A.2
  • 32
    • 0029028111 scopus 로고
    • Functional implications of kappa opiate receptor mediated modulation of glutamate transmission in the output regions of the basal ganglia in rodent and primate models of Parkinson's disease
    • 32. Maneuf, Y.; Mitchell, I. J.; Crossman, A. R.; Woodruff, G. N.; Brotchie, J. M., Functional implications of kappa opiate receptor mediated modulation of glutamate transmission in the output regions of the basal ganglia in rodent and primate models of Parkinson's disease. Brain Research, 683, 102-108 1995.
    • (1995) Brain Research , vol.683 , pp. 102-108
    • Maneuf, Y.1    Mitchell, I.J.2    Crossman, A.R.3    Woodruff, G.N.4    Brotchie, J.M.5
  • 35
    • 0000024912 scopus 로고
    • Altered tonic activity of neurons in the globus pallidus and subthalamic nucleus in the primate MPTP model of parkinsonism
    • Carpenter, M. B.; Jayaraman A., eds. New York: Plenum Press
    • 35. Miller, W. C.; Delong, M. R. Altered tonic activity of neurons in the globus pallidus and subthalamic nucleus in the primate MPTP model of parkinsonism. In: Carpenter, M. B.; Jayaraman A., eds. Advances in behavioral biology, 32. The basal ganglia II. Structure and function-current concepts. New York: Plenum Press; 1987:395-403.
    • (1987) Advances in Behavioral Biology, 32. The Basal Ganglia II. Structure and Function-current Concepts , pp. 395-403
    • Miller, W.C.1    Delong, M.R.2
  • 36
    • 0024397741 scopus 로고
    • Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • 36. Mitchell, I. J.; Clarke, C. E. et al., Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience, 32, 213-226 1989.
    • (1989) Neuroscience , vol.32 , pp. 213-226
    • Mitchell, I.J.1    Clarke, C.E.2
  • 37
    • 0028848314 scopus 로고
    • Reversal of parkinsonian symptoms by intrastriatal and systemic manipulations of EAA and dopamine transmission in the bilateral 6-OHDA lesioned marmoset
    • 37. Mitchell, I. J.; Hughes, N.; Carroll, C. B.; Brotchie, J. M. B., Reversal of parkinsonian symptoms by intrastriatal and systemic manipulations of EAA and dopamine transmission in the bilateral 6-OHDA lesioned marmoset. Behavioral Pharmacology, 6, 492-508 1995.
    • (1995) Behavioral Pharmacology , vol.6 , pp. 492-508
    • Mitchell, I.J.1    Hughes, N.2    Carroll, C.B.3    Brotchie, J.M.B.4
  • 38
    • 0011215838 scopus 로고
    • Reversal of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in the primate
    • 38. Mitchell, I. J.; Brotchie, J. M.; Cooper, A. J.; Crossman, A. R., Reversal of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in the primate. European Journal of Neuroscience, 4 (suppl.), 4050 1990.
    • (1990) European Journal of Neuroscience , vol.4 , Issue.SUPPL. , pp. 4050
    • Mitchell, I.J.1    Brotchie, J.M.2    Cooper, A.J.3    Crossman, A.R.4
  • 40
    • 0025924779 scopus 로고
    • 3H]-801 binding to subpopulations of NMDA receptors
    • 3H]-801 binding to subpopulations of NMDA receptors. Neuroscience Letters, 122, 21-24 1991.
    • (1991) Neuroscience Letters , vol.122 , pp. 21-24
    • Monaghan, D.T.1
  • 41
    • 0011254021 scopus 로고
    • Distributions of NMDA receptor subtypes correspond to specific receptor subunits
    • 41. Monaghan, D. T.; Clark, H. C.; Schneider, B. E. Distributions of NMDA receptor subtypes correspond to specific receptor subunits. Soc. Neurosci. Abstr., 19(2): 1356, 557.9; 1993.
    • (1993) Soc. Neurosci. Abstr. , vol.19 , Issue.2 , pp. 1356
    • Monaghan, D.T.1    Clark, H.C.2    Schneider, B.E.3
  • 42
    • 0026725656 scopus 로고
    • A pilot study of N-methyl-D-aspartate (NMDA) antagonist in Parkinson's disease
    • 42. Montastruc, J. L.; Rascol, O. et al., A pilot study of N-methyl-D-aspartate (NMDA) antagonist in Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry, 85 (7), 630-631 1992.
    • (1992) Journal of Neurology, Neurosurgery and Psychiatry , vol.85 , Issue.7 , pp. 630-631
    • Montastruc, J.L.1    Rascol, O.2
  • 43
    • 0026721811 scopus 로고
    • Heteromeric NMDA receptors: Molecular and functional distribution of subtypes
    • 43. Monyer, H.; Sprengel, R. et al., Heteromeric NMDA receptors: molecular and functional distribution of subtypes. Science, 256, 1217-1221 1992.
    • (1992) Science , vol.256 , pp. 1217-1221
    • Monyer, H.1    Sprengel, R.2
  • 44
    • 0026419327 scopus 로고
    • Molecular cloning and characterization of the rat NMDA receptor
    • 44. Moriyoshi, K.; Masu, M. et al., Molecular cloning and characterization of the rat NMDA receptor. Nature, 354, 774-776 1991.
    • (1991) Nature , vol.354 , pp. 774-776
    • Moriyoshi, K.1    Masu, M.2
  • 45
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP-5
    • 45. Morris, R. G. M.; Anderson, E.; Lynch, G. S.; Baudry, M., Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP-5. Nature, 319, 774-776 1986.
    • (1986) Nature , vol.319 , pp. 774-776
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 47
    • 0025260716 scopus 로고
    • Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracerebral infusion of the neurotoxin MPTP
    • 47. Palombo, E.; Perrino, L. J.; Bankiewski, K. S. et al., Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracerebral infusion of the neurotoxin MPTP. Journal of Neuroscience, 10 (3), 860-869 1990.
    • (1990) Journal of Neuroscience , vol.10 , Issue.3 , pp. 860-869
    • Palombo, E.1    Perrino, L.J.2    Bankiewski, K.S.3
  • 48
    • 0026633793 scopus 로고
    • NBQX does not affect learning and memory tasks in mice: A comparison with D-CPPene and ifenprodil
    • 48. Parada, J.; Czuczwar, S. J.; Turski, W. A., NBQX does not affect learning and memory tasks in mice: a comparison with D-CPPene and ifenprodil. Cognitive Brain Research, 1, 67-71 1992.
    • (1992) Cognitive Brain Research , vol.1 , pp. 67-71
    • Parada, J.1    Czuczwar, S.J.2    Turski, W.A.3
  • 49
    • 0026500108 scopus 로고
    • Differential regulation of striatal preproenkephalin mRNA by D1 and D2 dopamine receptors
    • 49. Pollack, A. E.; Wooten, G. F., Differential regulation of striatal preproenkephalin mRNA by D1 and D2 dopamine receptors. Molecular Brain Research, 12, 111-119 1992.
    • (1992) Molecular Brain Research , vol.12 , pp. 111-119
    • Pollack, A.E.1    Wooten, G.F.2
  • 50
    • 0025743758 scopus 로고
    • Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrroli-2-one (HA-966)
    • 50. Pullan, L. M.; Verticelli, A. M.; Paschetto, K. A., Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrroli-2-one (HA-966). European Journal of Pharmacology, 208, 25-29 1991.
    • (1991) European Journal of Pharmacology , vol.208 , pp. 25-29
    • Pullan, L.M.1    Verticelli, A.M.2    Paschetto, K.A.3
  • 51
    • 0025661932 scopus 로고
    • Minireview: Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification
    • 51. Reynolds, I. J., Minireview: modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification. Life Sciences, 47, 1785-1792 1990.
    • (1990) Life Sciences , vol.47 , pp. 1785-1792
    • Reynolds, I.J.1
  • 52
  • 53
    • 0023219060 scopus 로고
    • Excitotoxicity and the NMDA receptor
    • 53. Rothman, S. M.; Olney, J. W., Excitotoxicity and the NMDA receptor. Trends in Neurosciences, 10 (7), 299-302 1987.
    • (1987) Trends in Neurosciences , vol.10 , Issue.7 , pp. 299-302
    • Rothman, S.M.1    Olney, J.W.2
  • 54
    • 0027469171 scopus 로고
    • Anxiolytic-like and antinociceptive effects of MK-801 accompanied by sedation and ataxia in primates
    • 54. Rupniak, N. M.; Boyce, S.; Tye, S.; Cook, G.; Iversen, S. D., Anxiolytic-like and antinociceptive effects of MK-801 accompanied by sedation and ataxia in primates. Pharmacology and Biochemistry of Behavior, 44 (1), 153-156 1993.
    • (1993) Pharmacology and Biochemistry of Behavior , vol.44 , Issue.1 , pp. 153-156
    • Rupniak, N.M.1    Boyce, S.2    Tye, S.3    Cook, G.4    Iversen, S.D.5
  • 56
    • 0028226981 scopus 로고
    • Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat
    • 56. Standaert, D. G.; Testa, C. M.; Young, A. B.; Penney, J. B., Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. Journal of Comparative Neurology, 343, 1-16 1994.
    • (1994) Journal of Comparative Neurology , vol.343 , pp. 1-16
    • Standaert, D.G.1    Testa, C.M.2    Young, A.B.3    Penney, J.B.4
  • 57
    • 0026766877 scopus 로고
    • Structure and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • 57. Sugihara, H.; Moriyoshi, K. Structure and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochemical and Biophysical Research Communications 185(3): 826-832.6; 1992.
    • (1992) Biochemical and Biophysical Research Communications , vol.185 , Issue.3 , pp. 826-8326
    • Sugihara, H.1    Moriyoshi, K.2
  • 58
    • 0026052472 scopus 로고
    • Mechanism underlying protective effect of MK-801 against NMDA-stimulated neuronal injury in vivo
    • 58. Uematsu, D.; Greenberg, J. H. et al., Mechanism underlying protective effect of MK-801 against NMDA-stimulated neuronal injury in vivo. Journal of Cerebral Blood Flow and Metabolism, 11, 779-785 1991.
    • (1991) Journal of Cerebral Blood Flow and Metabolism , vol.11 , pp. 779-785
    • Uematsu, D.1    Greenberg, J.H.2
  • 59
    • 0001610688 scopus 로고
    • Increased neuronal activity in the subthalamic nucleus (STN) of MPTP treated monkeys
    • 59. Wichmann, T.; Bergman, H.; DeLong, M. R., Increased neuronal activity in the subthalamic nucleus (STN) of MPTP treated monkeys. Movement Disorders, 5, 78 1990.
    • (1990) Movement Disorders , vol.5 , pp. 78
    • Wichmann, T.1    Bergman, H.2    DeLong, M.R.3
  • 60
    • 0027405347 scopus 로고
    • Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro
    • 60. Williams, K.; Russell, S. L. et al., Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron, 10, 267-278 1993.
    • (1993) Neuron , vol.10 , pp. 267-278
    • Williams, K.1    Russell, S.L.2
  • 62
    • 0026560041 scopus 로고
    • Cloning, expression and modulation of a mouse NMDA receptor subunit
    • 62. Yamazaki, M.; Mori, H. et al., Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS, 300, 39-45 1992.
    • (1992) FEBS , vol.300 , pp. 39-45
    • Yamazaki, M.1    Mori, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.