Clonotypic Differences in Signaling from CD94 (kp43) on NK Cells Lead to Divergent Cellular Responses

Journal of Immunology

Volumn 157, Issue 7, 1996, Pages 2804-2812

  Brumbaugh, Kathryn M ^a   Pérez Villar, Juan J ^b   Dick, Christopher J ^a   Schoon, Renee A ^a   López Botet, Miguel ^b   Leibson, Paul J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; ENZYME PRECURSOR; ISOENZYME; KLRD1 PROTEIN, HUMAN; KLRD1 PROTEIN, MOUSE; LECTIN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOTRANSFERASE; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; ZAP70 PROTEIN, HUMAN; ZAP70 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL CLONE; CELL CULTURE; COMPARATIVE STUDY; CYTOTOXICITY; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOLECULAR GENETICS; MOUSE; NATURAL KILLER CELL; PATHOLOGY; PHYSIOLOGY; SARCOMA; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD94; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; ENZYME PRECURSORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MAST-CELL SARCOMA; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TUMOR CELLS, CULTURED; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0030266705     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
2. Ljunggren, H.-G., and K. Karre. 1990. In search of the "missing self": MHC molecules and NK cell recognition. Immunol. Today 11:237.
3. Moretta, L., E. Ciccone, M. C. Mingari, R. Biassoni, and A. Moretta. 1994. Human natural killer cells: origin, clonality, specificity, and receptors. Adv. Immunol. 55:341.
4. Trinchieri, G. 1994. Recognition of major histocompatibility complex class I antigens by natural killer cells. J Exp. Med. 180:417.
5. Yokoyama, W. M. 1995. Natural killer cell receptors specific for major histocompatibility complex class I molecules. Proc. Natl. Acad. Sci. USA 92:3081.
6. Leibson, P. J. 1995. MHC-recognizing receptors: they're not just for T cells anymore. Immunity 3:5.
7. Yokoyama, W. M., L. B. Jacobs, O. Kanagawa, E. M. Shevach, and C. I. Cohen. 1989. A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins. J. Immunol. 143:1379.
8. + IL-2-activated natural killer cells. Nature 358: 66.
9. Kane, K. P. 1994. Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. J. Exp. Med. 179:1011.
10. Mason, L. H., J. R. Ortaldo, H. A. Young, V. Kumar, M. Bennett, and S. K. Anderson. 1995. Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). J. Exp. Med. 182:293.
11. Stoneman, E. R., M. Bennett, J. An, K. A. Chesnut, E. K. Wakeland, J. B. Scheerer, M. J. Siciliano, V. Kumar, and P. A. Mathew. 1995. Cloning and characterization of 5E6(Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells. J. Exp. Med. 182:305.
12. Ciccone, E., D. Pende, O. Viale, A. Than, C. Di Dinato, A. M. Orengo, R. Biassoni, S. Verdiani, A. Amorosco, A. Moretta, and L. Moretta. 1992. Involvement of HLA class I alleles in NK cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J. Exp. Med. 176:963.
13. Litwin, V., J. Gumperz, P. Parham, J. H. Philips, and L. L. Lanier. 1994. NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J. Exp. Med. 180:537.
14. Lanier, L. L., J. E. Gumperz, P. Parham, L. Melero, M. López-Botet, and J. H. Phillips. 1995. The NKB1 and HP-3E4 NK cell receptors are structurally distinct glycoproteins and independently recognize polymorphic HLA-B and HLA-C molecules. J. Immunol. 154:3320.
15. Colonna, M., and J. Samaridis. 1995. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268:405.
16. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M. S. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E. O. Long. 1995. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2:439.
17. D'Andrea, A., C. Chang, K. Franz-Bacon, T. McClanahan, J. H. Phillips, and L. L. Lanier. 1995. Molecular cloning of NKB1: a natural killer cell receptor for HLA-B allotypes. J. Immunol. 155:2306.
18. + T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody. J. Immunol. 144:3238.
19. + T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 monoclonal antibody. J. Immunol. 147:714.
20. Chang, C., A. Rodriguez, M. Carretero, M. López-Botet, J. H. Phillips, and L. L. Lanier. 1995. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Eur. J. Immunol. 25:2433.
21. Moretta, A., M. Vitale, S. Sivori, S. C. Bottino, L. Morelli, R. Augugliaro, M. Barbaresi, D. Pende, E. Ciccone, M. López-Botet, and L. Moretta. 1994. Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J. Exp. Med. 180:545.
22. Mason, L. H., H. Yagita, and J. R. Ortaldo. 1994. LGL-1: a potential triggering molecule on murine NK cells. J. Leukocyte Biol. 55:362.
23. Melero, I., A. Salmeron, M. A. Balboa, J. Aramburu, and M. López-Botet. 1994. Tyrosine kinase-dependent activation of human NK cell functions upon stimulation through a 58-kDa surface antigen selectively expressed on discrete subsets of NK cells and T lymphocytes. J. Immunol. 152:1662.
24. Rolstad, B., K. Wonigeit, and J. T. Vaage. 1994. Alloreactive rat natural killer (NK) cells in vivo and in vitro: the role of the major histocompatibility complex (MHC). In Natural Immunity to Normal Hemopoietic Cells. B. Rolstad, ed. CRC Press, Ann Arbor, p. 99.
25. Pérez-Villar, J. J., L. Melero, A. Rodriguez, M. Carretero, J. Aramburu, S. Sivori, A. M. Orengo, A. Moretta, and M. López-Botet. 1995. Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen. J. Immunol. 154:5779.
26. Moretta, A., S. Sivori, M. Vitale, D. Pende, L. Morelli, R. Augugliaro, C. Bottina, and L. Moretta. 1995. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 182: 875.
27. Windebank, K. P., R. T. Abraham, G. Powis, R. A. Olsen, T. J. Barna, and P. J. Leibson. 1988. Signal transduction during human natural killer cell activation: inositol phosphate generation and regulation by cyclic AMP. J. Immunol. 141: 3951.
28. Perussia, B., and G. Trincheiri. 1984. Antibody 3G8, specific for the human neutrophil Fc receptor, reacts with natural killer cells. J. Immunol. 132:1410.
29. Barnstable, C. J., W. F. Bodmer, G. Brown, G. Galfre, C. Milstein, A. F. Williams, and A. Ziegler. 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens: new tools for genetic analysis. Cell 14:9.
30. Orloff, D. G., S. J. Frank, F. A. Robey, A. M. Weissman, and R. D. Klausner. 1989. Biochemical characterization of the η chain of the T-cell receptor: a unique subunit related to ζ. J. Biol. Chem. 264:14812.
31. Ting, A. T., L. M. Karnitz, R. A. Schoon, R. T. Abraham, and P. J. Leibson. 1992. Fcγ receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-γ1 and PLC-γ2 in natural killer cells. J. Exp. Med 176:1751.
32. Ting, A. T., C. J. Dick, R. A. Schoon, L. M. Karnitz, R. T. Abraham, and P. J. Leibson. 1995. Interaction between lck and syk family tyrosine kinases in Fcγ receptor-initiated activation of natural killer cells. J. Biol. Chem. 270:16415.
33. lck. J. Leukocyte Biol. 52:565.
34. Bonnema, J. D., L. M. Karnitz, R. A. Schoon, R. T. Abraham, and P. J. Leibson. 1994. Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity. J. Exp. Med. 180:1427.
35. Augustine, J. A., S. L. Sutor, and R. T. Abraham. 1991. Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes. Mol. Cell. Biol. 11:4431.
36. Leibson, P. J. 1996. Viewpoints: signal transduction during natural killer cell activation. Nat. Immun. 14:117.
37. Vivier, E., A. J. da Silva, M. Ackerly, H. Levine, C. E. Rudd, and P. Anderson. 1993. Association of a 70-kDa tyrosine phosphoprotein with the CD16:ζ:γ complex expressed in human natural killer cells. Eur. J. Immunol. 23:1872.
38. lck activation. J. Exp. Med. 176:1745.
39. Kanakaraj, P., B. Duckworth, L. Azzoni, M. Kamoun, L. C. Cantley, and B. Perussia. 1994. Phosphatidylinositol-3 kinase activation induced upon FcγRIIIA-ligand interaction. J. Exp. Med. 179:551.
40. Fry, M. J., and M. D. Waterfield. 1993. Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control. Philos. Trans. R. Soc. Lond. Biol. 340:337.
41. Hu, P., B. Margolis, E. Y. Skolnik, R. Lammers, A. Ullrich, and J. Schlessinger. 1992. Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Mol. Cell. Biol. 12: 981.
42. Klippel, A., J. A. Escobedo, W. J. Fantl, and L. T. Williams. 1992. The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor receptor. Mol Cell. Biol. 1992:1451.
43. McGlade, C. J., C. Ellis, M. Reeduk, D. Anderson, G. Mbamalu, A. D. Reith, G. Panayotou, P. End, A. Bernstein, A. Kazlauskas, M. D. Waterfield, and T. Pawson. 1992. SH2 domains of the p85 subunit of phosphatidylinositol 3-kinase regulate binding to growth factor β receptors. Mol. Cell. Biol. 12:991.
44. Myers, M. G., J. M. Backer, X. J. Sun, S. Shoelson, P. Hu, I. Schlessinger, M. Yoakim, B. Schaffhausen, and M. F. White. 1992. IRS-1 activates phosphatidylinositol 3-kinase by associating with src homology 2 domains of p85α. Proc. Natl. Acad. Sci. USA 89:10350.
45. Yano, H., S. Nakanishi, K. Kimura, N. Hanai, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1993. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268:25846.
46. Kaufman, D. S., R. A. Schoon, M. J. Robertson, and P. J. Leibson. 1995. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc. Natl. Acad. Sci. USA 92:6484.
47. Seaman, W. E., E. Eriksson, R. Dobrow, and J. B. Imboden. 1987. Inositol trisphosphate is generated by a rat natural killer cell tumor in response to target cells or to cross-linked monoclonal antibody OX-34: possible signaling role for the OX-34 determinant during activation by target cells. Proc. Natl. Acad. Sci. USA 84:4239.
48. Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P. M. Allen. 1994. Partial T cell signaling: altered phospho-ζ and lack of Zap70 recruitment in APL-induced T cell anergy. Cell 79:913.
49. Madrenas, J., R. L. Wange, J. L. Wang, N. Isakov, L. E. Samelson, and R. N. Germain. 1995. ζ phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267:515.
50. Burshtyn, D. N., A. M. Scharenberg, N. Wagtmann, S. Rajagopalan, K. Berrada, T. Yi, J.-P. Kinet, and E. O. Long. 1996. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 4:77.