Motor and cargo interactions

European Journal of Biochemistry

Volumn 262, Issue 1, 1999, Pages 19-25

  Sheetz, Michael P ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cytoplasmic dynein; Endoplasmic reticulum; Golgi; Kinectin; Kinesin; Membrane traffic; Microtubule transport; Residue transport; Saltatory movements

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; KINETIN;

CYTOSKELETON; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; MICROTUBULE; NERVE FIBER TRANSPORT; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

ANIMALS; KINESIN; MICROTUBULES;

EID: 0033563024     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00340.x     Document Type: Short Survey

References (97)

1. 1. Nakagawa, T., Tanaka, Y., Matsuoka, E., Kondo, S., Okada, Y., Noda, Y., Kanai, Y. & Hirokawa, N. (1997) Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc. Natl Acad. Sci. USA 94, 9654-9659.
2. 2. Yamashita, R. & May, G. (1998) Motoring along the hyphae, molecular motors and the fungal cytoskeleton. Curr. Opin. Cell Biol. 10, 74-79.
3. 3. Allen, R., Metuzals, D., Tasaki, I., Brady, S. & Gilbert, S. (1982) Fast . axonal transport in squid giant axon. Science 218, 1127-1129.
4. 4. Block, S., Goldstein, L. & Schnapp, B. (1990) Bead movement by single kinesin molecules studied with optical tweezers. Nature 348, 348-352.
5. 5. Wang, Z., Khan, S. & Sheetz, M. (1995) Single cytoplasmic dynein molecule movements, characterization and comparison with kinesin. Biophys. J. 69, 2011-2023.
6. 6. Hamm-Alvarez, S., Kim, P. & Sheetz, M. (1993) Regulation of vesicle transport in CV-1 cells and extracts. J. Cell Sci. 106, 955-966.
7. 7. Burkhardt, J., Echeverri, C., Nilsson, T. & Vallee, R. (1997) Over-expression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol. 139, 469-484.
8. 8. Blocker, A., Severin, F., Burkhardt, J., Bingham, J., Yu, H., Olivo, J., Schroer, T., Hyman, A. & Griffiths, G. (1997) Molecular requirements for bidirectional movement of phagosomes along microtubules. J. Cell. Biol. 137, 113-129.
9. 9. Muresan, V., Godek, C., Reese, T. & Schnapp, B. (1996) Plus-end motors override minus-end motors during transport of squid axon vesicles on microtubules. J. Cell Biol. 135, 383-397.
10. 10. Jiang, M. & Sheetz, M. (1995) Cargo-activated ATPase activity of kinesin. Biophys. J. 68, 283S-284S.
11. 11. Ferro, K. & Collins, C. (1995) Microtubule-independent phospholipid stimulation of cytoplasmic dynein ATPase activity. J. Biol. Chem 270, 4492-4496.
12. 12. Vale, R., Schnapp, B., Reese, T. & Sheetz, M. (1985) Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell 40, 559-569.
13. 13. Sheetz, M. & Yu, H. (1996) Regulation of kinesin and cytoplasmic dynein-driven organelle motility. Semin. Cell Dev. Biol. 7, 329-334.
14. 14. Vallee, R. & Sheetz, M. (1996) Targeting of motor proteins. Science 271, 1539-1544.
15. 15. Elluru, R., Bloom, G. & Brady, S. (1995) Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Mol. Biol. Cell. 6, 21-40. (Erratum published in 6, 1261.)
16. 16. Lippincott-Schwartz, J. (1998) Cytoskeletal proteins and Golgi dynamics. Curr. Opin. Cell Biol. 10, 52-59.
17. 17. Niclas, J., Allan, V. & Vale, R. (1996) Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport. J. Cell Biol. 133, 585-593.
18. 18. Lindesmith, L., McIlvain, J., Argon, Y. & Sheetz, M. (1997) Phosphotransferases associated with the regulation of kinesin motor activity. J. Biol. Chem 272, 22929-22933.
19. 19. Marlowe, K., Farshori, P., Torgerson, R., Anderson, K., Miller, L. & McNiven, M. (1998) Changes in kinesin distribution and phosphorylation occur during regulated secretion in pancreatic acinar cells. Eur J. Cell Biol. 75, 140-152.
20. 20. Lee, K. & Hollenbeck, P. (1995) Phosphorylation of kinesin in vivo correlates with organelle association and neurite outgrowth. J. Biol. Chem 270, 5600-5605.
21. 21. Vernos, I. & Karsenti, E. (1996) Motors involved in spindle assembly and chromosome segregation, Curr. Opin. Cell Biol. 8, 4-9.
22. 22. Okada, Y., Sato-Yoshitake, R. & Hirokawa, N. (1995) The activation of protein kinase A pathway selectively inhibits anterograde axonal transport of vesicles but not mitochondria transport or retrograde transport in vivo. J. Neurosci. 15, 3053-3064.
23. 23. Karki, S., Tokito, M. & Holzbaur, E. (1997) Casein kinase II binds to and phosphorylates cytoplasmic dynein. J. Biol. Chem 272, 5887-5891.
24. 24. Rothwell, S. & Calvert, V. (1997) Activation of human platelets causes post-translational modifications to cytoplasmic dynein. Thromb. Haemost. 78, 910-918.
25. 25. Bloom, G. & Goldstein, L. (1998) Cruising along microtubule highways, how membranes move through the secretory pathway. J. Cell Biol. 140, 1277-1280.
26. 26. Hotta, K., Tanaka, K., Mino, A., Kohno, H. & Takai, Y. (1996) Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor. Biochem. Biophys. Res. Commun. 225, 69-74.
27. 27. Alberts, A., Bouquin, N., Johnston, L. & Treisman, R. (1998) Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. J. Biol. Chem 273, 8616-8622.
28. 28. Echeverri, C., Paschal, B., Vaughan, K. & Vallee, R. (1996) Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol. 132, 617-633.
29. 29. Criswell, P. & Asai, D. (1998) Evidence for four cytoplasmic dynein heavy chain isoforms in rat testis. Mol. Biol. Cell 9, 237-247.
30. 30. Criswell, P., Ostrowski, L. & Asai, D. (1996) A novel cytoplasmic dynein heavy chain, expression of DHC1b in mammalian ciliated epithelial cells. J. Cell Sci. 109, 1891-1898.
31. 31. Vaisberg, E., Grissom, P. & McIntosh, J. (1996) Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles. J. Cell Biol. 133, 831-842.
32. 32. Moreira, J., Dodane, V. & Reese, T. (1998) Immunoelectronmicroscopy of soluble and membrane proteins with a sensitive postembedding method. J. Histochem. Cytochem. 46, 847-834.
33. 33. Stenoien, D. & Brady, S. (1997) Immunochemical analysis of kinesin light chain function. Mol. Biol. Cell 8, 675-689.
34. 34. Meng, Y., Wilson, G., Avery, M., Varden, C. & Balczon, R. (1997) Suppression of the expression of a pancreatic beta-cell form of the kinesin heavy chain by antisense oligonucleotides inhibits insulin secretion from primary cultures of mouse beta-cells. Endocrinology 138, 1979-1987.
35. 35. Amaratunga, A., Leeman, S., Kosik, K. & Fine, R. (1995) Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon. J. Neurochem. 64, 2374-2376.
36. 36. Minin, A. (1997) Dispersal of Golgi apparatus in nocodazole-treated fibroblasts is a kinesin-driven process. J. Cell Sci. 110, 2495-2505.
37. 37. Marples, D., Barber, B. & Taylor, A. (1996) Effect of a dynein inhibitor on vasopressin action in toad urinary bladder. J. Physiol. (London) 490, 767-774.
38. 38. Marples, D., Schroer, T., Ahrens, N., Taylor, A., Knepper, M. & Nielsen, S. (1998) Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct. Am. J. Physiol. 274, F384-F394.
39. 39. Seiler, S., Nargang, F., Steinberg, G. & Schliwa, M. (1997) Kinesin is essential for cell morphogenesis and polarized secretion in Neurospora crassa. EMBO J. 16, 3025-3034.
40. 40. Tanaka, Y., Kanai, Y., Okada, Y., Nonaka, S., Takeda, S., Harada, A. & Hirokawa, N. (1998) Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering mitochondria. Cell 93, 1147-1158.
41. 41. Miyake, K. & McNeil, P. (1995) Vesicle accumulation and exocytosis at sites of plasma membrane disruption. J. Cell Biol. 131, 1737-1745.
42. 42. De Vos, K., Goossens, V., Boone, E., Vercammen, D., Vancompernolle, K., Vandenabeele, P., Haegeman, G., Fiers, F. & Grooten, J. (1998) The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region. J. Biol. Chem 273, 9673-9680.
43. 43. DeZwaan, T., Ellingson, E., Pellman, D. & Roof, D. (1997) Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration. J. Cell Biol. 138, 1023-1040.
44. 44. Pereira, A., Dalby, B., Stewart, R., Doxsey, S. & Goldstein, L. (1997) Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. J. Cell Biol. 136, 1081-1090.
45. 45. Khodjakov, A., Lizunova, E., Minin, A., Koonce, M. & Gyoeva, F. (1998) A specific light chain of kinesin associates with mitochondria in cultured cells. Mol. Biol. Cell 9, 333-343.
46. 46. Gindhart, J., Desai, C., Beushausen, S., Zinn, K. & Goldstein, L. (1998) Kinesin light chains are essential for axonal transport in Drosophila. J. Cell Biol. 141, 443-454.
47. 47. Hurd, D. & Saxton, W. (1996) Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics 144, 1075-1085.
48. 48. Hurd, D., Stern, M. & Saxton, W. (1996) Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila. Genetics 142, 195-204.
49. 49. Harada, A., Takei, Y., Kanai, Y., Tanaka, Y., Nonaka, S. & Hirokawa, N. (1998) Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J. Cell Biol. 141, 51-59.
50. 50. Fath, K., Trimbur, G. & Burgess, D. (1997) Molecular motors and a spectrin matrix associate with Golgi membranes in vitro. J. Cell Biol. 139, 1169-1181.
51. 51. Pol, A., Onega, D. & Enrich, C. (1997) Identification of cytoskeleton-associated proteins in isolated rat liver endosomes. Biochem. J. 327, 741-746.
52. 52. Leung, E., Print, C., Parry, D., Closey. D., Lockhart, P., Skinner, S., Batchelor, D. & Krissansen, G. (1996) Cloning of novel kinectin splice variants with alternative C-termini, structure, distribution and evolution of mouse kinectin. Immunol. Cell Biol. 74, 421-433.
53. 53. Morris, R. & Scholey, J. (1997) Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos. J. Cell Biol. 138, 1009-1022.
54. 54. Cole, D., Diener, D., Himelblau, A., Beech, P., Fuster, J. & Rosenbaum, J. (1998) Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT), IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J. Cell Biol. 141, 993-1008.
55. 55. Nakajima, T., Miura, I., Kashiwagi, A. & Nakamura, M. (1997) Molecular cloning and expression of the KIF3A gene in the frog brain and testis. Zool. Sci. 14, 917-921.
56. 56. Yamazaki, H., Nakata, T., Okada, Y. & Hirokawa, N. (1995) KIF3A/B, a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J. Cell Biol. 130, 1387-1399.
57. 57. Pazour, G., Wilkerson. C. & Witman, G. (1998) A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J. Cell Biol. 141, 979-992.
58. 58. Kozminski, K., Johnson, K., Forscher, P. & Rosenbaum, J. (1993) A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc. Natl Acad. Sci. USA 90, 5519-5523.
59. 59. Piperno, G. & Mead, K. (1997) Transport of a novel complex in the cytoplasmic matrix of Chlamydomonas flagella. Proc. Natl Acad. Sci. USA 94, 4457-4462.
60. 60. Henson, J., Cole, D., Roesener, C., Capuano, S., Mendola, R. & Scholey, M. (1997) The heterotrimeric motor protein kinesin-II localizes to the midpiece and flagellum of sea urchin and sand dollar sperm. Cell Motil. Cytoskeleton 38, 29-37.
61. 61. Muresan, V., Bendala-Tufanisco, E., Hollander, B. & Besharse, J. (1997) Evidence for kinesin-related proteins associated with the axoneme of retinal photoreceptors. Exp. Eye Res. 64, 895-903.
62. 62. Wedaman, K., Meyer, D., Rashid, D., Cole, D. & Scholey, J. (1996) Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex. J. Cell Biol. 132, 371-380.
63. 63. Yamazaki, H., Nakata, T., Okada, Y. & Hirokawa, N. (1996) Cloning and characterization of KAP3, a novel kinesin superfamily-associated protein of KIF3A/3B. Proc. Natl Acad. Sci. USA 93, 8443-8448.
64. 64. Nagata, K., Puls, A., Futter, C., Aspenstrom, P., Schaefer, E., Nakata, T., Hirokawa, N. & Hall, A. (1998) The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KTF3. EMBO J. 17, 149-158.
65. 65. Shimizu, K., Kawabe, H., Minami, S., Honda, T., Takaishi, K., Shirataki, H. & Takai, Y. (1996) SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase. J. Biol. Chem 271, 27013-27017.
66. 66. Shimizu, K., Shirataki, H., Honda, T., Minami, S. & Takai, Y. (1998) Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide. J. Biol. Chem 273, 6591-6594.
67. 67. Dillman, 3rd, J., Dabney, L., Karki, S., Paschal, B., Holzbaur, E. & Pfister, K. (1996) Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport. J. Neurosci. 16, 6742-6752.
68. 68. Dillman, 3rd, J., Dabney, L. & Pfister, K. (1996) Cytoplasmic dynein is associated with slow axonal transport. Proc. Natl Acad. Sci. USA 93, 141-144.
69. 69. Liao, G. & Gundersen, G. (1998) Kinesin is a candidate for cross-bridging microtubules and intermediate filaments: selective binding of kinesin to detyrosinated tubulin and vimentin. J. Biol. Chem 273, 9797-9803.
70. 70. Kalderon, D. (1997) Hedgehog signalling, Ci complex cuts clasps. Curr. Biol. 7, R759-R762.
71. 71. Carson, J., Worboys, K., Ainger, K. & Barbarese, E. (1997) Translocation of myelin basic protein mRNA in oligodendrocytes requires microtubules and kinesin. Cell Motil. Cytoskeleton 38, 318-328.
72. 72. Chun, J., Gioio, A., Crispino, M., Giuditta, A. & Kaplan, B. (1996) Differential compartmentalization of mRNAs in squid giant axon. J. Neurochem. 67, 1806-1812.
73. 73. Harrison, R. & Huebner, E. (1997) Unipolar microtubule array is directly involved in nurse cell-oocyte transport. Cell Motil. Cytoskeleton 36, 355-362.
74. 74. Clark, I., Jan, L. & Jan, N. (1997) Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte epithelium neuron muscle Development 124, 461-470.
75. 75. Geiser, J., Schott, E., Kingsbury, T., Cole, N., Totis, L., Bhattacharyya, G., He, L. & Hoyt, M. (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol. Biol. Cell 8, 1035-1050.
76. 76. Huyett, A., Kahana, J., Silver, P., Zeng, X. & Saunders. W. (1998) The Kar3p and Kip2p motors function antagonistically at the spindle poles to influence cytoplasmic microtubule numbers. J. Cell Sci. 111, 295-301.
77. 77. Manning, B., Padmanabha, R. & Snyder, M. (1997) The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae. Mol. Biol. Cell 8, 1829-1844.
78. 78. Pidoux, A., LeDizet, M. & Cande, W. (1996) Fission yeast pkl1 is a kinesin-related protein involved in mitotic spindle function. Mol. Biol. Cell 7, 1639-1655.
79. 79. Saunders, W., Hornack, D., Lengyel, V. & Deng, C. (1997) The Saccharomyces cerevisiae kinesin-related motor Kar3p acts at preanaphase spindle poles to limit the number and length of cytoplasmic microtubules. J. Cell Biol. 137, 417-431.
80. 80. Shaw, S., Yeh, E., Maddox, P., Salmon, E. & Bloom, K. (1997) Astral microtubule dynamics in yeast, a microtubule-based searching mechanism for spindle orientation and nuclear migration into bud. J. Cell Biol. 139, 985-994.
81. 81. Kumar, J., Erickson, H. & Sheetz, M. (1998) Ultra-structural and biochemical properties of the 120 kDa form of kinectin in chicken. J. Biol. Chem. 273, 31738-31743.
82. 82. Print, C., Morris, C., Spurr, N., Rooke, L. & Krissansen, G. (1996) The CG-1 gene, a member of the kinectin and ES/130 family, maps to human chromosome band 14q22. Immunogenetics 43, 227-229.
83. 83. Zhu, Q., Hulen, D., Liu, T. & Clarke, M. (1997) The cluA-mutant of Dictyostelium identifies a novel class of protein required for dispersion of mitochondria. Proc. Natl Acad. Sci. USA 94, 7308-7313.
84. 84. Cook, K., Murphy, T., Nguyen, T. & Karpen, G. (1997) Identification of trans-acting genes necessary for centromere function in Drosophila melanogaster using centromere-defective minichromosomes. Genetics 145, 737-747.
85. 85. Desai, A., Deacon, H., Walczak, C. & Mitchison, T. (1997) A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts. Proc. Natl Acad. Sci. USA 94, 12378-12383.
86. 86. Cottingham, F. & Hoyt, M. (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J. Cell Biol. 138, 1041-1053.
87. 87. Merdes, A., Ramyar, K., Vechio, J. & Cleveland, D. (1996) A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell 87, 447-458.
88. 88. Molina, I., Baars, S., Brill, J., Hales, K., Fuller, M. & Ripoll, P. (1997) A chromatin-associaled kinesin-related protein required for normal mitotic chromosome segregation in Drosophila. J. Cell Biol. 139, 1361-1371.
89. 89. Ruden, D., Cui, W., Sollars, V. & Alterman, M. (1997) A Drosophila kinesin-like protein, Klp38B, functions during meiosis, mitosis and segmentation. Dev. Biol. 191, 284-296.
90. 90. Alphey, L., Parker, L., Hawcroft, G., Guo, Y., Kaiser, K. & Morgan, G. (1997) KLP38B, a mitotic kinesin-related protein that binds PP1. J. Cell Biol. 138, 395-409.
91. 91. Ohkura, H., Torok, T., Tick, G., Hoheisel, J., Kiss, I. & Glover. D. (1997) Mutation of a gene for a Drosophila kinesin-like protein, Klp38B, leads to failure of cytokinesis. J. Cell Sci. 110, 945-954.
92. 92. Robbins, D., Nybakken, K., Kobayashi, R., Sisson, J., Bishop, J. & Therond, P. (1997) Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell 90, 225-234.
93. 93. Tokai, N., Fujimoto-Nishiyama, A., Toyoshima, Y., Yonemura, Y., Tsukita, S., Inoue, J. & Yamamota, T. (1996) Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle. EMBO J. 15, 457-467.
94. 94. Chang, P., LeGuellec, K. & Houliston, E. (1996) Immunodetection of cytoskeletal structures and the Eg5 motor protein on deep-etch replicas of Xenopus egg cortices isolated during the cortical rotation. Biol. Cell 88, 89-98.
95. 95. Lin, S., Pfister, K. & Collins, C. (1996) Comparison of the intracellular distribution of cytoplasmic dynein and kinesin in cultured cells: motor protein location does not reliably predict function. Cell Motil. Cytoskeleton 34, 299-312.
96. 96. Bruno, G., Tinsley, J., Minke, P. & Plamann, M. (1996) Genetic interactions among cytoplasmic dynein, dynactin, and nuclear distribution mutants of Neurospora crassa. Proc. Natl Acad. Sci. USA 93, 4775-4780.
97. 97. Chiu, Y., Xiang, X., Dawe, A. & Morris, N. (1997) Deletion of nudC, a nuclear migration gene of Aspergillus nidulans, causes morphological and cell wall abnormalities and is lethal. Mol. Biol. Cell 8, 1735-1749.