Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex

Journal of Cell Biology

Volumn 132, Issue 3, 1996, Pages 371-380

  Wedaman, Karen P ^a   Meyer, David W ^a   Rashid, Dana J ^a   Cole, Douglas G ^a   Scholey, Jonathan M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; KINESIN; POLYPEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; ELECTRON MICROSCOPY; ENZYME LOCALIZATION; ENZYME STRUCTURE; ENZYME SUBUNIT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEA URCHIN;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM-BINDING PROTEINS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; KINESIN; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ELECTRON; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUSCLE PROTEINS; OSMOLAR CONCENTRATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEA URCHINS;

EID: 0030031255     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.3.371     Document Type: Article

References (56)

1. Aitken, A. 1990. Identification of Protein Consensus Sequences. Ellis Horwood publishers, NY. 151-160.
2. Aizawa, H., Y. Sekine, R. Tekamura, Z. Zhang, M Nangaku, and N. Hirokawa 1992. Kinesin family in murine central nervous system. J Cell Biol 119: 1287-1296.
3. Biou, V., J. F. Gibrat, J M Levin, B. Robson, and J. Garnier. 1988. Secondary structure prediction: combination of three different methods. Protein Eng. 2: 185-191.
4. Bloom, G. S., M. C. Wagner, K. K. Pfister, and S. T. Brady. 1988. Native structure and physical properties of bovine brain kinesin and identification of the ATP binding subunit polypeptide Biochemistry. 27:3409-3416.
5. Bloom, G. S., and S. Endow. 1994. Kinesins. Protein Profile. 1:1059-1116.
6. Brady, S T. 1985. A novel brain ATPase with properties expected for the fast axonal transport motor. Nature (Lond.). 317:73-75.
7. Buster, D., and J. M. Scholey. 1991. Purification and assay of kinesin from sea urchin eggs and early embryos. J. Cell Sci. 14s:109-115.
8. Cohn, S. A., A. L. Ingold, and J. M. Scholey 1989. Quantitative analysis of sea urchin egg kinesin-driven microtubule motility. J. Biol. Chem. 264:4290-4297.
9. Cole, D. G., W. Z. Cande, R. J. Baskin, D. A. Skoufias, C. J. Hogan, and J. M. Scholey. 1992 Isolation of a sea urchin egg kinesin-related protein using peptide antibodies J. Cell Sci. 101:291-301.
10. Cole, D. G., S. W. Chinn, K. P. Wedaman, K. Hall, T. Vuong, and J. M. Scholey. 1993. Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature (Lond.). 366:268-270.
11. Cole, D. G., W. M. Saxton, K. B. Sheehan, and J. M. Scholey, 1994. A "slow" homotetrameric kinesin related motor protein purified from Drosophila embryos J. Biol. Chem. 269:22913-22916.
12. Cole, D. G., and J. M. Scholey. 1995a. Structural variations among the kinesins. Trends Cell Biol. 5:259-262.
13. Cole, D. G., and J. M. Scholey. 1995b. Purification of kinesin-related protein complexes from eggs and embryos. Biophys. J. 68:158s-162s.
14. Craig, R., R. Smith, and J. Kendrick-Jones. 1983. Light chain phosphorylation controls the conformation of smooth muscle and nonmuscle myosin Nature (Lond.). 302:436-439.
15. Cyr, J. L., K. K. Pfister, G. S. Bloom, C. A Slaughter, and S. T Brady. 1991. Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc. Natl. Acad. Sci. USA. 88:10114-10118.
16. deCuevas, M., T. Tao, and L. S Goldstein. 1992. Evidence that the stalk of Drosophila kinesin heavy chain is an alpha-helical coiled coil. J. Cell Biol. 116:957-965.
17. Devereux, J., P. Haeberli, and O. Smithies. 1984 A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
18. Doolittle, R. F. 1987. Of ORFs and URFs. University Science Books, Mill Valley, CA, 103 pp.
19. Gauger, A. K., and L. S. B. Goldstein. 1993. The Drosophila kinesin light chain. Primary structure and interaction with kinesin heavy chain. J. Biol. Chem. 268:13657-13666.
20. Goldstein, L. S. B. 1993. With apologies to Sheherazade: tails of 1001 kinesin motors. Annu. Rev Genet. 27:319-351.
21. Gribskov, M., and J. Devereux. 1991. Sequence Analysis Primer. Stockton Press, London. 1-279.
22. Hackney, D. D., J. D. Levitt, and D. D. Wagner. 1991. Characterization of α2β2 and α2 forms of kinesin. Biochem. Biophys. Res. Commun 174:810-815.
23. Hackney, D. D., J. D. Levitt, and J. Suhan. 1992. Kinesin undergoes a 9 S to 6 S conformational transition. J. Biol Chem. 267:8696-8701.
24. 85.95 in the mitotic apparatus of sea urchin embryos. Dev. Biol. 171:182-194.
25. Hirokawa, N , K. K. Pfister, H. Yorifuji, M. C. Wagner, S. T. Brady, and G. S. Bloom. 1989. Submolecular domain of brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell. 56:867-878.
26. Hisanaga, S., H. Murofushi, K. Okuhara, R. Sato, Y Masuda, H Sakai, and N. Hirokawa. 1989. The molecular structure of adrenal medulla kinesin. Cell Motil. Cytoskeleton 12:264-272.
27. Johnson, C S., D. Buster, and J. M. Scholey. 1990. Light chains of sea urchin kinesin identified by immunoadsorption. Cell Motil. Cytoskeleton. 16:204-213.
28. Kondo, S., R. Sato-Yoshitake, Y. Noda, H. Aizawa, T. Nakata, Y Matsuura, and N. Hirokawa. 1994. Kif3A is a new microtubule-based motor in the nerve axon J. Cell Biol. 125:1095-1107
29. Kuznetsov, S. A., E. A. Vaisberg, N. A. Shanina, N. N. Magretova, V. Y. Chernyak, and V.I. Gelfand. 1988. The quaternary structure of bovine brain kinesin EMBO (Eur. Mol. Biol. Organ.) J. 7.353-356.
30. Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105-132.
31. Lupas, A., M. Van Dyke, and J. Stock. 1991. Predicting coiled coils from protein sequences Science (Wash DC). 252:1162-1164.
32. Olmsted, J. B. 1981. Affinity-purification of antibodies from diazotized paper blots of heterogeneous protein samples J. Biol. Chem. 256:11955-11957.
33. Pesavento, P. A , R. J. Stewart, and L. S. Goldstein. 1994. Characterization of the KIp68D kinesin-like protein in Drosophila: possible roles in axonal transport. J. Cell Biol. 127:1041-1048.
34. 85/95. J. Mol. Biol 252:157-162.
35. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
36. Sawin, K. E., T. J. Mitchison, and L. G. Wordeman. 1992. Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies. J Cell Sci. 101:303-313.
37. Scholey, J. M., B. Neighbors, J. R. McIntosh, and E. D. Salmon. 1984. Isolation of microtubules and a dynein-like MgATPase from unfertilized sea urchin eggs. J Biol. Chem. 259:6516-6525.
38. Scholey, J M., M. E. Porter, P M. Grissom, and J. R. McIntosh. 1985. Identification of kinesin in sea urchin eggs and evidence for its localization in the mitotic spindle. Nature (Lond.). 318:483-486.
39. Scholey, J M., J. Heuser, J. T Yang, and L. S. H Goldstein. 1989. Identification of globular mechanochemical heads of kinesin. Nature (Lond ). 338:355-357.
40. Shakir, M., T. Fukushige, H Yasuda, J. Miwa, and S S. Siddiqui. 1993. C. elegans osm-3 gene mediating osmotic avoidance behavior encodes a kinesin-like protein. Neuroreport. 4:891-894.
41. Skoufias, D. A., and J. M. Scholey. 1993. Cytoplasmic microtubule-based motor proteins. Curr. Opin. Cell Biol. 5.95-104.
42. Skoufias, D., D. G. Cole, K. P. Wedaman, and J M Scholey. 1994. The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding. J. Biol. Chem. 269:1477-1485.
43. Steinhardt, R. A., G. Bi, and J. M. Alderton. 1994. Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science (Wash. DC). 263:390-393.
44. Tabish, M , Z. K. Siddiqui, K. Nishikawa, and S. S. Siddiqui. 1995. Exclusive expression of C. elegans osm-3 kinesin gene in chemosensory neurons open to the external environment J Mol. Biol. 247:377-389.
45. Tyler, J. M., and D. Branton. 1980. Rotary shadowing of extended molecules dried from glycerol. J. Ultrastr. Res. 71:95-102
46. Vale, R. D., T. S. Reese, and M. P. Sheetz. 1985. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 42: 39-50.
47. Vale, R. D., and L. S. B. Goldstein. 1990. One motor many tails; an expanding repertoire of force-generating molecules. Cell. 60:883-885.
48. Vale, R. D. 1992. Microtubule motors, many new models off the assembly line. Trends Biochem. Sci. 17:300-304.
49. Walker, R. A., and M. P. Sheetz. 1993 Cytoplasmic microtubule-associated motors. Annu. Rev. Biochem. 62:429-451.
50. Walther, Z., M. Vashishtha, and J. L. Hall. 1994. The Chlamydomonas fla10 gene encodes a novel kinesin-homologous protein. J. Cell Biol. 126:175-188.
51. Wedaman, K. P., A. E. Knight, J. Kendrick-Jones, and J. M. Scholey. 1993 Sequences of sea urchin kinesin light chain isoforms. J. Mol. Biol 231:155-158.
52. Wilson, R., R. Ainscough, K. Anderson, C Baynes, M. Berks, J. Bonfield, J. Burton, M. Connell, T Copsy, J. Cooper, et al 1994 2.2 Mb of contiguous nucleotide sequence from chromosome III of C elegans. Nature (Lond.). 368:32-38.
53. Wright, B. D , J. H. Henson, K P. Wedaman, P. J. Willy, J. N. Morand, and J. M. Scholey. 1991. Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm J Cell Biol. 113:817-833.
54. Wright, B D., M. Terasaki, and J. M. Scholey. 1993. Roles of kinesin and kinesin-like proteins in sea urchin embryonic cell division, evaluation using antibody microinjection. J. Cell Biol. 123:681-689.
55. Yamazaki, H., T. Nakata, Y. Okada, and N. Hirokawa 1995. KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J. Cell Biol. 130: 1387-1399.
56. Yang, J. T., R. A. Laymon, and L. S. B. Goldstein 1989. A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell. 56:879-889.