A chromatin-associated kinesin-related protein required for normal mitotic chromosome segregation in Drosophila

Journal of Cell Biology

Volumn 139, Issue 6, 1997, Pages 1361-1371

  Molina, Isabel ^a   Baars, Sigrid ^a   Brill, Julie A ^b   Hales, Karen G ^b   Fuller, Margaret T ^b,c   Ripoll, Pedro ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; KINESIN; MICROTUBULE PROTEIN; RNA;

ANAPHASE; ANIMAL TISSUE; ARTICLE; BRAIN; CHROMATIN; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE MUTATION; IN SITU HYBRIDIZATION; LARVA; MALE; MITOSIS; NONHUMAN; PLOIDY; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; ANAPHASE; ANIMALS; BRAIN; CELL DIVISION; CHROMATIN; CHROMOSOMES; DROSOPHILA; DROSOPHILA PROTEINS; GENES, INSECT; INSECT PROTEINS; INTRONS; KINESIN; LARVA; MITOSIS; MOLECULAR SEQUENCE DATA; PLOIDIES; RESTRICTION MAPPING; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0031439136     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.6.1361     Document Type: Article

References (54)

1. Afshar, K., N. Barton, R.S. Hawley, and L.S.B. Goldstein. 1995. DNA binding and meiotic chromosomal localization of the Drosophila NOD kinesin-like protein. Cell. 81:129-138.
2. Afshar, K., J. Scholey, and R.S. Hawley. 1995. Identification of the chromosome localization domain of the Drosophila Nod kinesin-like protein. J. Cell Biol. 131:833-843.
3. Alphey, L., L. Parker, G. Hawcroft, Y. Guo, K. Kaiser, and G. Morgan. 1997. KLP38B - a mitotic kinesin-related protein which binds PP1. J. Cell Biol. 138:395-109.
4. Axton, J.M., V. Dombradi, P.T.W. Cohen, and D.M. Glover. 1990. One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis. Cell. 63:33-46.
5. Bajer, A. 1982. Functional autonomy of monopolar spindle and evidence for oscillatory movement in mitosis. J. Cell Biol. 93:33-48.
6. Bajer, A.S., J. Mole-Bajer, M. De Brabander, J. De Mey, G. Geuens, and S. Paulaitis. 1980. Aster migration and functional autonomy of monopolar spindle. In Microtubules and Microtubule inhibitors. Vol. II. M. de Brabender and J.D. Mey, editors. Elsevier, New York. 399-425.
7. Casal, J., C. González, and P. Ripoll. 1990. Spindles and centrosomes during male meiosis in Drosophila melanogaster. Eur. J. Cell Biol. 51:38-44.
8. Casal, J., C. González, F. Wandosell, J. Avila, and P. Ripoll. 1990. Abnormal meiotic spindles cause a cascade of defects during spermatogenesis in asp males of Drosophila. Development. 108:251-260.
9. Cavener, D.R., and S.C. Ray. 1991. Eukaryotic start and stop translation sites. Nucleic Acids Res. 19:3185-3192.
10. Churchill, M.E., and A.A. Travers. 1991. Protein motifs that recognize structural features of DNA. Trends Biochem Sci. 16:92-97.
11. Cooley, L., R. Kelley, and A. Spradling. 1988. Insertional mutagenesis of the Drosophila genome with single P elements. Science. 239:1121-1128.
12. Devereaux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
13. Endow, S.A., and M. Hatsumi. 1991. A multimember kinesin gene family in Drosophila. Proc. Natl. Acad. Sci. 88:4424-4427.
14. Enos, A.P., and N.R. Morris. 1990. Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans. Cell. 60:1019-1027.
15. Foe, V. 1989. Mitotic domains reveal early commitment of cells in Drosophila development. Development. 107:1-22.
16. Fuller, M.T. 1995. Riding the polar winds: chromosomes motor down east. Cell. 81:5-8.
17. Gatti, M., and B.S. Baker. 1989. Genes controlling essential cell-cycle functions in Drosophila melanogaster. Genes Dev. 3:438-453.
18. Glover, D.M., M.H. Leibowitz, D.A. McLean, and H. Parry. 1995. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell. 81:95-105.
19. González, C., J. Casal, and P. Ripoll. 1988. Functional monopolar spindles caused by mutation in mgr, a cell division gene of Drosophila melanogaster. J. Cell Sci. 89:39-47.
20. González, C. and D.M. Glover. 1994. Techniques for studying mitosis in Drosophila. In The Cell Cycle: A Practical Approach. R. Brookes and P. Fantes, editors. IRL, Oxford University Press, Oxford, UK. 143-175.
21. Heald, R., R. Tournebize, T. Blank, R. Sandaltzopoulos, P. Becker, A. Hyman, and E. Karsenti. 1996. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature. 382:420-425.
22. Heck, M.M.S., A. Pereira, P. Pesavento, Y. Yannoii, A.C. Spradling, and L.S.B. Goldstein. 1993. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J. Cell Biol. 123:665-679.
23. Heuer, J.G., K. Li, and T.C. Kaufman. 1995. The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis. Development. 121:209-218.
24. Kashina, A.S., R.J. Baskin, D.G. Cole, K.P. Wedaman, W.M. Saxton, and J.M. Scholey. 1996. A bipolar kinesin. Nature. 379:270-272.
25. Kashina, A.S., J.M. Scholey, J.D. Leszyk, and W.M. Saxton. 1996. An essential bipolar mitotic motor. Nature. 384:225.
26. Krieg, P.A., and D.A. Melton. 1987. In vitro RNA synthesis with SP6 RNA polymerase. Methods Enzymol. 155:397-415.
27. Lindsley, D.L., and G.G. Zimm. 1992. The Genome of Drosophila melanogaster. Academic Press, New York. 1-1133.
28. Lupas, A., D.M. Van, and J. Stock. 1991. Predicting coiled coils from protein sequences. Science. 252:1162-1164.
29. Mazia, D. 1961. Mitosis and the physiology of cell division. In The Cell. Vol. III. Jean Brachet and Alfred E. Mirsky, editors. Academic Press Inc. LTD, London. 77-412.
30. Mole-Bajer, J. 1975. The role of centrioles in the development of the astral spindle (newt). Cytobios. 13:117-140.
31. Moore, J.D., and S.A. Endow. 1996. Kinesin proteins: a phylum of motors for microtubule-based motility. Bioessays. 18:207-219.
32. + kinesin-like gene and extra-centromeric sequences are required for transmission of a Drosophila minichromosome. Cell. 81:139-148.
33. Nangaku, M., R. Sato-Yoshitake, Y. Okada, Y. Noda, R. Takemura, H. Yamazaki, and N. Hirokawa. 1994. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell. 79:1209-1220.
34. Nigg, E.A. 1993. Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases. Trends Cell Biol. 3:296-301.
35. Nomura, N., T. Nagase, N. Miyajima, T. Sazuka, A. Tanaka, S. Sato, N. Seiki, Y. Kawarabayasi, K. Ishikawa, and S. Tabata. 1994. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 1. 1:223-229.
36. Ohkura, H., T. Torok, G. Tick, J. Hoheisel, I. Kiss, and D.M. Glover. 1997. Mutation of a gene for a Drosophila kinesin-like protein, Klp38B, leads to failure of cytokinesis. J. Cell Sci. 110:945-954.
37. Okada, Y., H. Yamazaki, Y. Sekine-Aizawa, and N. Hirokawa. 1995. The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell. 81:769-780.
38. Piperno, G., and M.T. Fuller. 1985. Monoclonal antibodies specific for an acetylated form of α-tubulin recognize the antigen in cilia and flagella from a variety of organisms. J Cell Biol. 101:2085-2094.
39. Rattner, J.B., and M.W. Berns. 1976. Distribution of microtubules during centriole separation in rat kangaroo (Protorous) cells. Cytobios. 15:37-43.
40. Rieder, C.L., and S.P. Alexander. 1990. Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells. J. Cell Biol. 110:81-95.
41. Rieder, C.L., and E.D. Salmon. 1994. Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle. J. Cell Biol. 124:223-233.
42. Rieder, C.L., E.A. Davison, L.C. Jensen, L. Cassimeris, and E.D. Salmon. 1986. Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindle. J Cell Biol. 103:581-591.
43. Ruden, D., W. Cui, V. Sollars, and M. Alterman. 1997. A Drosophila kinesin-like protein, Klp38B, functions during meiosis, mitosis, and segmentation. Dev. Biol. In press.
44. Sablin, E.P., F.J. Kull, R. Cooke, R.D. Vale, and R.J. Fletterick. 1996. Crystal structure of the motor domain of the kinesin-related motor ncd. Nature. 380:555-559.
45. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 14.12-14.13.
46. Sunkel, C.E., and D.M. Glover. 1988. polo, a mitotic mutant of Drosophila displaying abnormal spindle poles. J Cell Sci. 89:25-38.
47. Theurkauf, W.E., and R.S. Hawley. 1992. Meiotic spindle assembly in Drosophila females: behavior of nonexchange chromosomes and the effects of mutations in the nod kinesin-like protein. J Cell Biol. 116:1167-1180.
48. Vernós, I., and E. Karsenti. 1995. Chromosomes take the lead in spindle assembly. Trends Cell Biol. 5:297-301.
49. Vernós, I., J. Raats, T. Hirano, J. Heasman, E. Karsenti, and C. Wylie. 1995. Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell. 81:117-127.
50. Wang, S.-Z., and R. Adler. 1995. Chromokinesin: a DNA-binding, kinesin-like nuclear protein. J. Cell Biol. 128:761-768.
51. Waters, J.C., R.W. Cole, and C.L. Rieder. 1993. The force-producing mechanism for centrosome separation during spindle formation in vertebrates is intrinsic to each aster. J. Cell Biol. 122:361-372.
52. Wilson, P.C., M.T. Fuller, and G.G. Borisy. 1997. Monastral bipolar spindles: implications for dynamic centrosome organization. J. Cell Sci. 110: 451-464.
53. Zhang, P., and R.S. Hawley. 1990. The genetic analysis of distributive segregation in Drosophila melanogaster. II. Further genetic analysis of the nod locus. Genetics. 125:115-127.
54. Zhang, P., B.A. Knowles, L.S. Goldstein, and R.S. Hawley. 1990. A kinesin-like protein required for distributive chromosome segregation in Drosophila. Cell. 62:1053-1062.