A hypothesis for what conformation of the major adduct of(+)-anti-B[a]PDE (N2-dG) causes G→T versus G→A mutations based upon a correlation between mutagenesis and molecular modeling results

Carcinogenesis

Volumn 20, Issue 1, 1999, Pages 95-102

  Kozack, Richard E ^a   Shukla, Rajiv ^a   Loechler, Edward L ^a  

^a Boston University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; DNA;

ARTICLE; DNA ADDUCT; DNA CONFORMATION; FRAMESHIFT MUTATION; MOLECULAR MODEL; MUTAGENICITY; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; COMPUTER SIMULATION; DEOXYGUANOSINE; DNA ADDUCTS; MODELS, MOLECULAR; MUTAGENESIS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; POINT MUTATION; THERMODYNAMICS;

EID: 0032896954     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.1.95     Document Type: Article

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