Microsatellite instability and mutated type II transforming growth factor-β receptor gene in gliomas

Cancer Letters

Volumn 112, Issue 2, 1997, Pages 251-256

  Izumoto, Shuichi ^a   Arita, Norio ^a   Ohnishi, Takanori ^a   Hiraga, Shoju ^a   Taki, Takuyu ^a   Tomita, Naohiro ^a   Ohue, Masayuki ^a   Hayakawa, Toru ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Glioma; Microsatellite instability; Tumor suppressor gene; Type II TGF receptor

Indexed keywords

DNA; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; ASTROCYTOMA; CARCINOGENESIS; CLINICAL ARTICLE; DNA DETERMINATION; FAMILIAL CANCER; FRAMESHIFT MUTATION; GENE DELETION; GENE MUTATION; GENE REPLICATION; GENETIC STABILITY; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN TISSUE; LEUKOCYTE; MUTATION RATE; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR GENE;

ASTROCYTOMA; DNA, NEOPLASM; DNA, SATELLITE; ELECTROPHORESIS; GLIOBLASTOMA; HUMANS; MICROSATELLITE REPEATS; MUTATION; PHENOTYPE; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 0031590968     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04583-1     Document Type: Article

References (29)

1. [1] Aaltonen, L.A., Peltomaki, P., Leach, F.S., Sistonen, P., Pylkkanen, L., Mecklin, J.-P., Jarvin, H., Powell, S.M., Jen, J., Hamilton, S.R., Petersen, G.M., Kinzler, K.W., Vogelstein, B. and de la Chappelle, A. (1993) Clues to the pathogenesis of familial colorectal cancer, Science, 260, 812-816.
2. [2] Burks, R.T., Kessis, T.D., Cho, K.R. and Hedrick, L. (1994) Microsatellite instability in endometrial carcinoma, Oncogene, 9, 1163-1166.
3. [3] Dams, E., Van de Kelft, E.J.Z., Martin, J.-J., Verlooy, J. and Willems, P.J. (1995) Instability of microsatellites in human gliomas, Cancer Res,., 55, 1547-1549.
4. [4] Franzen, P., ten Dijke, P., Ichijo, H., Yamashita, H., Schulz, P., Heldin, C.-H. and Miyazono, K. (1993) Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor, Cell, 75, 681-692.
5. [5] Gyapay, G., Morisette, J., Vignal, A., Dib, C., Fizamens, C., Philippe, M., Marc, S., Bernardi, G., Lathrop, M. and Weissenbach, J. (1994) The 1993-1994 Genethon human genetic linkage map, Nature Genet., 7, 246-339.
6. [6] Hamilton, S.R., Liu, B., Parsons, R.E., Papadopoulos, N., Jen, J., Powell, S.M., Krush, A.J., Berk, T., Cohen, Z., Tetu, B., Burger, P.C., Wood, P.A., Taqi, F., Booker, S.V., Petersen, G.M., Offerhaus, G.J.A., Tersmette, A.C., Giardiello, F.M., Vogelstein, B. and Kinzler, K.W. (1995) The molecular basis of Turcot's syndrome, N. Engl. J. Med., 332, 839-847.
7. [7] Hannon, G.J. and Beach, D. (1994) p15INK4B is a potential effector of TGF-β-induced cell cycle arrest, Nature, 371, 257-261.
8. [8] Inagaki, M., Moustakas, A., Lin, H.Y., Lodish, H.F. and Carr, B.I. (1993) Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA, Proc. Nad. Acad. Sci. USA, 90, 5359-5363.
9. [9] Ionov, Y., Peinado, M.A., Malkhosyan, S., Shibata, D. and Perucho, M. (1993) Ubiquitous somatic mutation in simple repeated sequences reveals a new mechanism for colonic carcinogenesis, Nature, 363, 558-561.
10. [10] Ishimaru, G., Adachi, J., Shiseki, M., Yamaguchi, N., Muto, T. and Yokota, J. (1995) Microsatellite instability in primary and metastatic colorectal cancers, Int. J. Cancer, 64, 153-157.
11. [11] Jones, M.H., Yamakawa, K. and Nakamura, Y. (1992) Isolation and characterization of 19 dinucleotide repeat polymorphisms on chromosome 3p, Hum. Mol. Genet., 1, 131-133.
12. [12] Larson, A.A., Kern, S., Sommers, R.L., Yokota, J., Cavenee, W.K. and Hampton, G.M. (1996) Analysis of replication error (RER+) phenotypes in cervical carcinoma, Cancer Res., 56, 1426-1431.
13. [13] Lu, S.-L., Akiyama, Y., Nagasaki, H., Saitoh, K. and Yuasa, Y. (1995) Mutations of the transforming growth factor-β type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer, Biochem. Biophys. Res. Commun., 216, 452-457.
14. [14] Madisen, L., Holar, D.I., Holroyd, C.D., Crisp, M. and Hodges, M.E. (1987) DNA banking: the effects of storage of blood and isolated DNA on the integrity of DNA, Am. J. Med. Genet., 27, 378-390.
15. [15] Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R.S., Zborowska, E., Kinzler, K.W., Vogelstein, B., Brattain, M. and Willson, J.K.V. (1995) Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability, Science, 268, 1336-1338.
16. [16] Massague, J. (1990) The transforming growth factor-β family, Annu. Rev. Cell Biol., 6, 597-641.
17. 1, Br. J. Cancer, 70, 199-203.
18. [18] Myeroff, L.L., Parsons, R., Kim, S.-J., Hedrick, L., Cho, K.R., Orth, K., Mathis, M., Kinzler, K.W., Lutterbaugh, J., Park, K., Bang, Y.-J., Lee, H.Y., Park, J.-G., Lynch, H.T., Roberts, A.B., Vogelstein, B. and Markowitz, S.D. (1995) A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability, Cancer Res., 55, 5545-5547.
19. [19] Ogasawara, S., Maesawa, C., Tamura, G. and Satodate, R. (1995) Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma, Cancer Res., 55, 891-894.
20. [20] Palombo, F., Gallinari, P., Laccarino, I., Lettieri, T., Hughes, M., D'Arrigo, A., Truong, O., Hsuan, J.J. and Jiricny, J. (1995) GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells, Science, 268, 1912-1914.
21. [21] Parsons, R., Myeroff, L.L., Liu, B., Willson, J.K.V., Markowitz, S.D., Kinzler, K.W. and Vogelstein, B. (1995) Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer, Cancer Res., 55, 5548-5550.
22. [22] Parsons, R., Li, G.-M., Longley, M., Modrich, P., Liu, B., Berk, T., Hamilton, S.R., Kinzler, K.W. and Vogelstein, B. (1995) Mismatch repair deficiency in phenotypically normal human cells, Science, 268, 738-740.
23. [23] Polyak, K. (1996) Negative regulation of cell growth by TGFβ, Biochim. Biophys. Acta, 1242, 185-199.
24. [24] Pykett, M.J., Murphy, M., Harnish, P.R. and George, D.L. (1994) Identification of a microsatellite instability phenotype in meningiomas, Cancer Res., 54, 6340-6343.
25. [25] Tamura, G., Sakata, K., Maesawa, C., Suzuki, Y., Terashima, M., Satoh, K., Sekiyama, S., Suzuki, A., Eda, Y. and Satodate, R. (1995) Microsatellite alterations in adenoma and differentiated adenocarcinoma of the stomach, Cancer Res., 55, 1933-1936.
26. [26] Thibodeau, S.N., Bren, G. and Scaid, D. (1993) Microsatellite instability in cancer of the proximal colon, Science, 260, 816-819.
27. [27] Wang, J., Sun, L., Myeroff, L., Wang, X., Gentry, L.E., Yang, J., Liang, J., Zborowska, E., Markowitz, S., Willson, J.K.V. and Brattain, M.G. (1995) Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells, J. Biol. Chem., 270, 22044-22049.
28. [28] Wooster, R., Cleton-Jansen, A.-M., Collins, N., Mangion, J., Cornells, R.S., Cooper, C.S., Gusterson, B.A., Ponder, B.A., von Deimling, A. and Wiestler, O.D. (1994) Instability of short tandem repeats (microsatellites) in human cancers, Nature Genet., 6, 152-156.
29. [29] Zhao, Y. and Young, S.L. (1996) Requirement of transforming growth factor-β (TGF-β) type II receptor for TGF-β-induced proliferation and growth inhibition, J. Biol. Chem., 271, 2369-2372.