Inhibition of development of peripheral neuropathy in streptozotocin-induced diabetic rats with N-acetylcysteine

Diabetologia

Volumn 39, Issue 3, 1996, Pages 263-269

  Sagara, M ^a   Satoh, J ^a   Wada, R ^b   Yagihashi, S ^b   Takahashi, K ^a   Fukuzawa, M ^a   Muto, G ^a   Muto, Y ^a   Toyota, T ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Diabetic neuropathy; Glutathione; Motor nerve conduction; N acetylcysteine; Tumour necrosis factor ; Velocity

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; LIPID PEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFECT; MOTOR NERVE CONDUCTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SURAL NERVE;

EID: 0030022084     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00418340     Document Type: Article

References (34)

1. Boulton AJM (1993) Pathogenesis of diabetic neuropathy. In: Marshall SM, Home PD, Alberti KOMM, Krall LP (eds) The diabetes annual/7. Elsevier, Amsterdam, pp 192-210
2. Loven D, Schedl H, Wilson H et al. (1986) Effect of insulin and oral glutathione on glutathione levels and superoxide dismutase activities in organs of rats with streptozotocin-induced diabetes. Diabetes 35: 503-507
3. Tanaka S-I, Seino H, Satoh J et al. (1992) Increased in vivo production of tumor necrosis factor after development of diabetes in nontreated, long-term diabetic BB rats. Clin Immunol Immunopathol 62: 258-263
4. Sagara M, Satoh J, Zhu XP et al. (1994) Inhibition with N-acetylcysteine of enhanced production of tumor necrosis factor in streptozotocin-induced diabetic rats. Clin Immunol Immunopathol 71: 333-337
5. Beutler B, Cerami A (1987) Cachectin: more than a tumor necrosis factor. N Engl J Med 316: 379-385
6. Tracey KJ, Vlassara H, Cerami A (1989) Cachectin/tumour necrosis factor. Lancet I: 1122-1125
7. Editorial (1991) Acetylcysteine. Lancet 337: 1069-1070
8. Peristeris P, Clark BD, Gatti S et al. (1992) N-acetylcysteine and glutathione as inhibitors of tumor necrosis factor production. Cell Immunol 140: 390-399
9. Satoh J, Seino H, Abo T et al. (1989) Recombinant human tumor necrosis factor a suppresses autoimmune diabetes in nonobese diabetic mice. J Clin Invest 84: 1345-1348
10. Yagihashi S, Kamijo M, Ido Y, Mirrlees DJ (1990) Effects of long-term aldose reductase inhibition on development of experimental diabetic neuropathy. Diabetes 39: 690-696
11. Ellman GL (1958) A colorimetric method for determining low concentrations of mercaptons. Arch Biochem Biophys 74: 443-450
12. Yagi K (1976) A simple fluorometric assay for lipoperoxide in blood plasma. Biochem Med 15: 212-216
13. Malone JI, Knox G, Benford S, Tedesco TA (1980) Red cell sorbitol: an indicator of diabetic control. Diabetes 29: 861-864
14. Honma M, Satoh T, Takezawa J, Ui M (1977) An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue. Biochem Med 18: 257-273
15. Dyck PJ, Karnes J, Lais A, Lofgren EP, Stevens JC (1984) Pathologic alterations of the peripheral nervous system of humans. In: Peripheral neuropathy. Dyck PJ, Thomas PK, Lambert EH, Bunge R (eds) Saunders, Philadelphia, pp 760-870
16. Yagihashi S, Kamijo M, Watanabe K (1990) Reduced myelinated fiber size correlates with loss of axonal neurofilaments in peripheral nerve of chronically streptozotocin diabetic rats. Am J Pathol 136: 1365-1373
17. Sima AAF, Zhang W-X, Tze WJ, Tai J, Nathaniel V (1988) Diabetic neuropathy in STZ-induced diabetic rat and effect of allogeneic islet cell transplantation. Diabetes 37: 1129-1136
18. Yasuda H, Sonobe M, Yamashita M et al. (1989) Effect of prostaglandin E1 analogue TFC612 on diabetic neuropathy in streptozocin-induced diabetic rats. Diabetes 38: 832-838
19. Burgunder JM, Varriale A, Lauterberg BH (1989) Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur J Clin Pharmacol 36: 127-131
20. Meister A, Anderson ME (1983) Glutathione. Ann Rev Biochem 52: 711-760
21. Murakami K, Kondo T, Ohtsuka Y, Fujiwara Y, Shimada M, Kawakami Y (1989) Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus. Metabolism 38: 753-758
22. Lu CS, Ge J, Kuhlenkamp J, Kaplowitz N (1992) Insulin and glucocorticoid dependence of hepatic y-glutamylcysteine synthetase and glutathione synthesis in the rat. J Clin Invest 90: 524-532
23. Hunt VJ, Dean RT, Wolff SP (1988) Hydroxyl radical production and autoxidative glycosylation. Biochem J 256: 205-212
24. Barnett PA, Gonzalez RG, Chylack LT, Chylack LT Jr, Cheng H-M (1986) The effect of oxidation on sorbitol pathway kinetics. Diabetes 35: 426-432
25. Brownlee M, Cerami A, Vlassara H (1988) Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease. Diab Metab Rev 4: 437-451
26. Romero FJ, Segura-Aguilar J, Monsalve E et al. (1990) Antioxidant and glutathione-related enzymatic activities in rat sciatic nerve. Neurotoxicol Teratol 12: 603-605
27. 2 in human umbilical vein endothelial cells cultured in high glucose medium. Diabetologia 37: 264-269
28. Chaudhri G, Clark IA (1989) Reactive oxygen species facilitate the in vitro and in vivo lipopolysaccharide-induced release of tumor necrosis factor. J Immunol 143: 1290-1294
29. Cameron NE, Cotter MA, Maxfield EK (1993) Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats. Diabetologia 36: 299-304
30. Bravenboer B, Kappelle AC, Hamers FPT, Van Buren T, Erkelens DW, Gispen WH (1992) Potential use of glutathione for prevention and treatment of diabetic neuropathy in the streptozotocin-induced diabetic rat. Diabetologia 35: 813-817
31. Low PA (1987) Recent advances in the pathogenesis of diabetic neuropathy. Muscle Nerve 10: 121-128
32. Spies JM, Westland KW, Hodgkinson SJ, Pollard JD (1994) Intraneuronal tumor necrosis factor causes focal breakdown of the blood nerve barrier. Proc Peripheral Nerve Society Meeting, St. Paul, June 12-16, pp 146 (Abstract)
33. Mayer M, Noble M (1994) N-Acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci USA 91: 7496-7500
34. Vlassara H, Brownlee M, Manogue KR, Dinarello CA, Pasagian A (1988) Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science 240: 1546-1548