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Volumn 13, Issue 2, 1999, Pages 181-195

The aetiology of type I diabetes

Author keywords

Cows' milk protein; Environmental factors; Human leukocyte antigen (HLA); Major histocompatibility complex (MHC); Susceptibility genes; Type I diabetes; Viruses

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN; INSULIN; MILK PROTEIN;

EID: 0033495395     PISSN: 1521690X     EISSN: None     Source Type: Journal    
DOI: 10.1053/beem.1999.0015     Document Type: Article
Times cited : (17)

References (87)
  • 1
    • 0024542323 scopus 로고
    • The incidence of insulin dependent diabetes in England: A study in the Oxford region, 1985-6
    • Bingley P J, Gale E AM. The incidence of insulin dependent diabetes in England: a study in the Oxford region, 1985-6. British Medical Journal. 298:1989;558-560.
    • (1989) British Medical Journal , vol.298 , pp. 558-560
    • Bingley, P.J.1    Gale, E.A.2
  • 2
    • 0032964798 scopus 로고    scopus 로고
    • Autoantigens IA-2 and GAD in Type 1 (insulin-dependent) diabetes
    • Leslie R DG, Atkinson M A, Notkins A L. Autoantigens IA-2 and GAD in Type 1 (insulin-dependent) diabetes. Diabetologia. 42:1999;3-14.
    • (1999) Diabetologia , vol.42 , pp. 3-14
    • Leslie, R.D.1    Atkinson, M.A.2    Notkins, A.L.3
  • 4
    • 0000914177 scopus 로고
    • The epidemiology of diabetes mellitus
    • J. C Pickup, & G. Williams.
    • Green A, Sjolie A K, Eshoj O. The epidemiology of diabetes mellitus. Pickup J C, Williams G. Textbook of diabetes. 1992;1-16.
    • (1992) Textbook of Diabetes , pp. 1-16
    • Green, A.1    Sjolie, A.K.2    Eshoj, O.3
  • 5
    • 0027500910 scopus 로고
    • A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin dependent) diabetes mellitus
    • Karvonen M, Tuomilehto J, Libman I, LaPorte R. A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin dependent) diabetes mellitus. Diabetologia. 36:1993;883-892.
    • (1993) Diabetologia , vol.36 , pp. 883-892
    • Karvonen, M.1    Tuomilehto, J.2    Libman, I.3    Laporte, R.4
  • 6
    • 0031034666 scopus 로고    scopus 로고
    • Incidence of insulin-dependent diabetes mellitus among Sardinian heritage children born in Lazio region, Italy
    • Muntoni S A, Fonte M T, Stoduto S. Incidence of insulin-dependent diabetes mellitus among Sardinian heritage children born in Lazio region, Italy. Lancet. 349:1997;160-162.
    • (1997) Lancet , vol.349 , pp. 160-162
    • Muntoni, S.A.1    Fonte, M.T.2    Stoduto, S.3
  • 8
    • 0026560497 scopus 로고
    • Evidence for an environmental effect in the aetiology of insulin dependent diabetes in a transmigratory population
    • Bodansky H J, Staines A, Stephenson D. Evidence for an environmental effect in the aetiology of insulin dependent diabetes in a transmigratory population. British Medical Journal. 304:1992;1020-1022.
    • (1992) British Medical Journal , vol.304 , pp. 1020-1022
    • Bodansky, H.J.1    Staines, A.2    Stephenson, D.3
  • 9
    • 0028276510 scopus 로고
    • Early environmental events as a cause of IDDM. Evidence and implications
    • Leslie R DG, Elliot R B. Early environmental events as a cause of IDDM. Evidence and implications. Diabetes. 43:1994;843-850.
    • (1994) Diabetes , vol.43 , pp. 843-850
    • Leslie, R.D.1    Elliot, R.B.2
  • 10
    • 0031925611 scopus 로고    scopus 로고
    • Give us this day our daily germs
    • Rook G AW, Stanford J L. Give us this day our daily germs. Immunology Today. 19:1998;113-116.
    • (1998) Immunology Today , vol.19 , pp. 113-116
    • Rook, G.A.1    Stanford, J.L.2
  • 11
    • 0015883122 scopus 로고
    • Histocompatibility (HL-A) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus
    • Singal D P, Blajchman M A. Histocompatibility (HL-A) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus. Diabetes. 22:1973;429-432.
    • (1973) Diabetes , vol.22 , pp. 429-432
    • Singal, D.P.1    Blajchman, M.A.2
  • 12
    • 0027933734 scopus 로고
    • A genome-wide search for human type 1 diabetes susceptibility genes
    • Davies J L, Kawaguchi Y, Bennett S T. A genome-wide search for human type 1 diabetes susceptibility genes. Nature. 371:1994;130-136.
    • (1994) Nature , vol.371 , pp. 130-136
    • Davies, J.L.1    Kawaguchi, Y.2    Bennett, S.T.3
  • 13
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • Bell G I, Horita S, Karam J H. A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes. 33:1984;176-183.
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 14
    • 0032404079 scopus 로고    scopus 로고
    • Genetic susceptibility factors in type 1 diabetes: Linkage disequilibrium and functional analyses
    • She J X, Marron M P. Genetic susceptibility factors in type 1 diabetes: linkage disequilibrium and functional analyses. Current Opinion in Immunology. 10:1998;682-689.
    • (1998) Current Opinion in Immunology , vol.10 , pp. 682-689
    • She, J.X.1    Marron, M.P.2
  • 16
    • 0027428494 scopus 로고
    • Statistical evaluation of multiple locus linkage data in experimental species and relevance to human studies: Application to murine and human IDDM
    • Risch N, Ghosh S, Todd J A. Statistical evaluation of multiple locus linkage data in experimental species and relevance to human studies: application to murine and human IDDM. American Journal of Human Genetics. 53:1993;702-714.
    • (1993) American Journal of Human Genetics , vol.53 , pp. 702-714
    • Risch, N.1    Ghosh, S.2    Todd, J.A.3
  • 17
    • 17144452354 scopus 로고    scopus 로고
    • A search for type 1 diabetes susceptibility genes in families from the United Kingdom
    • Mein C A, Esposito L, Dunn M G. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nature Genetics. 19:1998;297-300.
    • (1998) Nature Genetics , vol.19 , pp. 297-300
    • Mein, C.A.1    Esposito, L.2    Dunn, M.G.3
  • 18
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman R S, McGinnis R E, Ewens W J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). American Journal of Human Genetics. 52:1993;506-516.
    • (1993) American Journal of Human Genetics , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 19
    • 0031720530 scopus 로고    scopus 로고
    • Genetic analysis of chromosome 2 in Type 1 diabetes. Analysis of putative loci IDDM7, IDDM12 and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster
    • Esposito L, Hill N J, Pritchard L E. Genetic analysis of chromosome 2 in Type 1 diabetes. Analysis of putative loci IDDM7, IDDM12 and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. Diabetes. 47:1998;1797-1799.
    • (1998) Diabetes , vol.47 , pp. 1797-1799
    • Esposito, L.1    Hill, N.J.2    Pritchard, L.E.3
  • 20
    • 17344372511 scopus 로고    scopus 로고
    • A second generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus
    • Concannon P, Gogolin-Ewens K J, Hinds D A. A second generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nature Genetics. 19:1998;292-296.
    • (1998) Nature Genetics , vol.19 , pp. 292-296
    • Concannon, P.1    Gogolin-Ewens, K.J.2    Hinds, D.A.3
  • 21
    • 0031831322 scopus 로고    scopus 로고
    • Sometimes it's hot, sometimes it's not
    • Lernmark A, Ott J. Sometimes it's hot, sometimes it's not. Nature Genetics. 19:1998;213-214.
    • (1998) Nature Genetics , vol.19 , pp. 213-214
    • Lernmark, A.1    Ott, J.2
  • 22
    • 0032401779 scopus 로고    scopus 로고
    • Genetics of autoimmune diabetes in animal models
    • McDuffie M. Genetics of autoimmune diabetes in animal models. Current Opinion in Immunology. 10:1998;704-709.
    • (1998) Current Opinion in Immunology , vol.10 , pp. 704-709
    • McDuffie, M.1
  • 23
    • 0025777873 scopus 로고
    • Genetic analysis of autoimmune type 1 diabetes mellitus in mice
    • Todd J A, Aitman T J, Cornall R J. Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature. 351:1991;542-547.
    • (1991) Nature , vol.351 , pp. 542-547
    • Todd, J.A.1    Aitman, T.J.2    Cornall, R.J.3
  • 25
    • 0029905302 scopus 로고    scopus 로고
    • Susceptibility to Type 1 diabetes: HLA-DQ and DR revisited
    • She J X. Susceptibility to Type 1 diabetes: HLA-DQ and DR revisited. Immunology Today. 17:1996;323-329.
    • (1996) Immunology Today , vol.17 , pp. 323-329
    • She, J.X.1
  • 26
    • 0030903745 scopus 로고    scopus 로고
    • Invited Anniversary review: HLA associated diseases
    • Thorsby E. Invited Anniversary review: HLA associated diseases. Human Immunology. 53:1997;1-11.
    • (1997) Human Immunology , vol.53 , pp. 1-11
    • Thorsby, E.1
  • 27
    • 0028989040 scopus 로고
    • HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first degree relatives of patients with IDDM
    • Pugliese A, Giannani R, Moromisato R. HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first degree relatives of patients with IDDM. Diabetes. 45:1995;608-613.
    • (1995) Diabetes , vol.45 , pp. 608-613
    • Pugliese, A.1    Giannani, R.2    Moromisato, R.3
  • 28
    • 0029006991 scopus 로고
    • DRB10403 protects against IDDM in Caucasians with the high-risk heterozygous DQA10301-DQB10302/DQA10501/DQB10201 genotype. Belgian Diabetes Registry
    • van der Awera B, van Waeyenberge C, Schuit F. DRB10403 protects against IDDM in Caucasians with the high-risk heterozygous DQA10301-DQB10302/DQA10501/DQB10201 genotype. Belgian Diabetes Registry. Diabetes. 44:1995;527-530.
    • (1995) Diabetes , vol.44 , pp. 527-530
    • Van Der Awera, B.1    Van Waeyenberge, C.2    Schuit, F.3
  • 29
    • 0031024575 scopus 로고
    • HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection
    • Undlein D E, Friede T, Rammensee H G. HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. Diabetes. 46:1977;143-149.
    • (1977) Diabetes , vol.46 , pp. 143-149
    • Undlein, D.E.1    Friede, T.2    Rammensee, H.G.3
  • 30
    • 0029968375 scopus 로고    scopus 로고
    • DR4 subtypes and their molecular properties in a population based study of Swedish childhood diabetes
    • Sanjeevi C B, Hook P, Landin-Olsson M. DR4 subtypes and their molecular properties in a population based study of Swedish childhood diabetes. Tissue Antigens. 47:1996;275-283.
    • (1996) Tissue Antigens , vol.47 , pp. 275-283
    • Sanjeevi, C.B.1    Hook, P.2    Landin-Olsson, M.3
  • 31
    • 0030701914 scopus 로고    scopus 로고
    • The effect of HLA-B allele on the IDDM risk defined by the DRB1*04 subtypes and DQB1*0302
    • Nejentsev S, Reijonen H, Adojaan B. The effect of HLA-B allele on the IDDM risk defined by the DRB1*04 subtypes and DQB1*0302. Diabetes. 45:1997;1888-1892.
    • (1997) Diabetes , vol.45 , pp. 1888-1892
    • Nejentsev, S.1    Reijonen, H.2    Adojaan, B.3
  • 32
    • 0342591877 scopus 로고
    • HLA-DQB1 gene contributes to the genetic susceptibility to insulin dependent diabetes mellitus
    • B. Dupont. New York: Springer-Verlag
    • Todd J A, Bell J I, McDevitt H O. HLA-DQB1 gene contributes to the genetic susceptibility to insulin dependent diabetes mellitus. Dupont B. Immunobiology of HLA. 1989;402-403 Springer-Verlag, New York.
    • (1989) Immunobiology of HLA , pp. 402-403
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 33
    • 0031690196 scopus 로고    scopus 로고
    • Prevention of diabetes in NOD mice by a mutated I-Ab transgene
    • Singer S M, Tisch R, Yang X D. Prevention of diabetes in NOD mice by a mutated I-Ab transgene. Diabetes. 47:1998;1570-1577.
    • (1998) Diabetes , vol.47 , pp. 1570-1577
    • Singer, S.M.1    Tisch, R.2    Yang, X.D.3
  • 34
    • 0025138978 scopus 로고
    • High frequency of aspartic acid at position 57 of HLA-DQ B-chain in Japanese IDDM patients and nondiabetic subjects
    • Awata T, Kuzuya T, Matsuda A. High frequency of aspartic acid at position 57 of HLA-DQ B-chain in Japanese IDDM patients and nondiabetic subjects. Diabetes. 39:1990;266-269.
    • (1990) Diabetes , vol.39 , pp. 266-269
    • Awata, T.1    Kuzuya, T.2    Matsuda, A.3
  • 35
    • 0025326199 scopus 로고
    • A combination of HLA-DQb Asp57-negative and HLA-DQa Arg52 confers susceptibility to insulin-dependent diabetes mellitus
    • Khalil I, d'Auriol L, Gobet M. A combination of HLA-DQb Asp57-negative and HLA-DQa Arg52 confers susceptibility to insulin-dependent diabetes mellitus. Journal of Clinical Investigation. 85:1990;1315-1319.
    • (1990) Journal of Clinical Investigation , vol.85 , pp. 1315-1319
    • Khalil, I.1    D'Auriol, L.2    Gobet, M.3
  • 36
    • 0031737601 scopus 로고    scopus 로고
    • Transmission of DQ haplotypes to patients with type 1 diabetes
    • Kawasaki E, Noble J, Erlich H. Transmission of DQ haplotypes to patients with type 1 diabetes. Diabetes. 47:1998;1970-1973.
    • (1998) Diabetes , vol.47 , pp. 1970-1973
    • Kawasaki, E.1    Noble, J.2    Erlich, H.3
  • 37
    • 0031035360 scopus 로고    scopus 로고
    • HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: Application of the haplotype method
    • Valdes A, McWeeney S, Thomson G. HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method. American Journal of Human Genetics. 60:1997;717-728.
    • (1997) American Journal of Human Genetics , vol.60 , pp. 717-728
    • Valdes, A.1    McWeeney, S.2    Thomson, G.3
  • 38
    • 0027217789 scopus 로고
    • Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
    • Braun J H, Jardetsky T S, Garga J C. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364:1993;33-39.
    • (1993) Nature , vol.364 , pp. 33-39
    • Braun, J.H.1    Jardetsky, T.S.2    Garga, J.C.3
  • 39
    • 0031847984 scopus 로고    scopus 로고
    • Molecular basis for HLA-DQ associations with IDDM
    • Nepom G T, Kowk W W. Molecular basis for HLA-DQ associations with IDDM. Diabetes. 47:1998;1177-1184.
    • (1998) Diabetes , vol.47 , pp. 1177-1184
    • Nepom, G.T.1    Kowk, W.W.2
  • 40
    • 0031911947 scopus 로고    scopus 로고
    • Genetic structure of IDDM1. Two separate regions in the major histocompatibility complex contribute to susceptibility or protection
    • Hanifi-Moghaddam P, de Knijf P, Roep B. Genetic structure of IDDM1. Two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Diabetes. 47:1998;263-269.
    • (1998) Diabetes , vol.47 , pp. 263-269
    • Hanifi-Moghaddam, P.1    De Knijf, P.2    Roep, B.3
  • 41
    • 0032502810 scopus 로고    scopus 로고
    • TAPASIN, DAXX, RGL2, HKE2, and four new genes (BING1,3 to 5) form a dense cluster at the centromeric end of the MHC
    • Herberg J A, Beck S, Trowsdale J. TAPASIN, DAXX, RGL2, HKE2, and four new genes (BING1,3 to 5) form a dense cluster at the centromeric end of the MHC. Journal of Molecular Biology. 277:1998;839-857.
    • (1998) Journal of Molecular Biology , vol.277 , pp. 839-857
    • Herberg, J.A.1    Beck, S.2    Trowsdale, J.3
  • 42
    • 0031667779 scopus 로고    scopus 로고
    • Apoptosis and the pathogenesis of IDDM. A question of life and death
    • Mauricio D, Mandrup-Poulsen T. Apoptosis and the pathogenesis of IDDM. A question of life and death. Diabetes. 47:1998;1537-1543.
    • (1998) Diabetes , vol.47 , pp. 1537-1543
    • Mauricio, D.1    Mandrup-Poulsen, T.2
  • 43
    • 0027959118 scopus 로고
    • Insulin-dependent diabetes mellitus and the major histocompatibility transporters TAP1 and TAP2: No association in a population with a high disease incidence
    • Cucca F, Congia M, Trowsdale J, Powis S H. Insulin-dependent diabetes mellitus and the major histocompatibility transporters TAP1 and TAP2: no association in a population with a high disease incidence. Tissue Antigens. 44:1994;234-240.
    • (1994) Tissue Antigens , vol.44 , pp. 234-240
    • Cucca, F.1    Congia, M.2    Trowsdale, J.3    Powis, S.H.4
  • 44
    • 0030948644 scopus 로고    scopus 로고
    • No independent associations of LMP2 and LMP7 polymorphism with susceptibility to develop IDDM
    • Undlein D, Akselen H E, Joner G. No independent associations of LMP2 and LMP7 polymorphism with susceptibility to develop IDDM. Diabetes. 46:1997;307-312.
    • (1997) Diabetes , vol.46 , pp. 307-312
    • Undlein, D.1    Akselen, H.E.2    Joner, G.3
  • 45
    • 0029970653 scopus 로고    scopus 로고
    • Association of HLA-DPB1*0301 with insulin dependent diabetes mellitus in Mexican-Americans
    • Erlich H A, Rotter J I, Chang J D. Association of HLA-DPB1*0301 with insulin dependent diabetes mellitus in Mexican-Americans. Diabetes. 45:1996;610-614.
    • (1996) Diabetes , vol.45 , pp. 610-614
    • Erlich, H.A.1    Rotter, J.I.2    Chang, J.D.3
  • 46
    • 0029953008 scopus 로고    scopus 로고
    • The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian multiplex families
    • Noble J A, Valdes A M, Cook M. The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian multiplex families. American Journal of Human Genetics. 59:1996;1134-1148.
    • (1996) American Journal of Human Genetics , vol.59 , pp. 1134-1148
    • Noble, J.A.1    Valdes, A.M.2    Cook, M.3
  • 47
    • 0030698020 scopus 로고    scopus 로고
    • HLA-associations in insulin-dependent diabetes mellitus: No independent association to particular DP genes
    • Lie B, Akselsen H E, Joner G. HLA-associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes. Human Immunology. 55:1997;170-175.
    • (1997) Human Immunology , vol.55 , pp. 170-175
    • Lie, B.1    Akselsen, H.E.2    Joner, G.3
  • 48
    • 0031833918 scopus 로고    scopus 로고
    • A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients
    • Cucca F, Goy J V, Kawaguchi Y. A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients. Nature Genetics. 19:1998;301-303.
    • (1998) Nature Genetics , vol.19 , pp. 301-303
    • Cucca, F.1    Goy, J.V.2    Kawaguchi, Y.3
  • 49
    • 0028871202 scopus 로고
    • Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
    • Bennett S T, Lucassen A M, Gough S C. Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genetics. 9:1995;284-292.
    • (1995) Nature Genetics , vol.9 , pp. 284-292
    • Bennett, S.T.1    Lucassen, A.M.2    Gough, S.C.3
  • 50
    • 16944366697 scopus 로고    scopus 로고
    • Insulin VNTR allele-specific effect in Type 1 diabetes depends on identity of untransmitted paternal allele
    • Bennett S T, Wilson A J, Esposito L. Insulin VNTR allele-specific effect in Type 1 diabetes depends on identity of untransmitted paternal allele. Nature Genetics. 17:1997;350-352.
    • (1997) Nature Genetics , vol.17 , pp. 350-352
    • Bennett, S.T.1    Wilson, A.J.2    Esposito, L.3
  • 51
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene transcribed in the human pancreas and the transcription level correlate with allelic variation at the INS-VNTR-IDDM2 susceptibility locus for type 1 diabetes
    • Pugliese A, Zeller M, Fernandez J A. The insulin gene transcribed in the human pancreas and the transcription level correlate with allelic variation at the INS-VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nature Genetics. 15:1997;293-297.
    • (1997) Nature Genetics , vol.15 , pp. 293-297
    • Pugliese, A.1    Zeller, M.2    Fernandez, J.A.3
  • 52
    • 0032486384 scopus 로고    scopus 로고
    • The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans
    • Paquette J, Giannoukakis N, Polychronakos C. The INS 5′ variable number of tandem repeats is associated with IGF2 expression in humans. Journal of Biological Chemistry. 273:1998;14158-14164.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 14158-14164
    • Paquette, J.1    Giannoukakis, N.2    Polychronakos, C.3
  • 53
    • 0031786680 scopus 로고    scopus 로고
    • Divergence between genetic determinants of IGF2 transcription levels in leukocytes and of IDDM2-encoded susceptibility to type 1 diabetes
    • Vafiadis P, Bennett S T, Todd J A. Divergence between genetic determinants of IGF2 transcription levels in leukocytes and of IDDM2-encoded susceptibility to type 1 diabetes. Journal of Clinical Endocrinology and Metabolism. 83:1998;2933-2939.
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 2933-2939
    • Vafiadis, P.1    Bennett, S.T.2    Todd, J.A.3
  • 54
    • 0029822895 scopus 로고    scopus 로고
    • Intrauterine growth pattern and risk of childhood onset insulin dependent (type 1) diabetes: Population based case-control study
    • Dahlquist G, Bennich S S, Kallen B. Intrauterine growth pattern and risk of childhood onset insulin dependent (type 1) diabetes: population based case-control study. British Medical Journal. 313:1996;1174-1177.
    • (1996) British Medical Journal , vol.313 , pp. 1174-1177
    • Dahlquist, G.1    Bennich, S.S.2    Kallen, B.3
  • 55
    • 9244244764 scopus 로고    scopus 로고
    • Confirmation of three susceptibility genes to insulin dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8
    • Luo D F, Buzzetti R, Rotter J I. Confirmation of three susceptibility genes to insulin dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8. Human Molecular Genetics. 5:1996;693-698.
    • (1996) Human Molecular Genetics , vol.5 , pp. 693-698
    • Luo, D.F.1    Buzzetti, R.2    Rotter, J.I.3
  • 56
    • 0030589302 scopus 로고    scopus 로고
    • Genomic structure and mapping of human FADD, an intracellular mediator of lymphocyte apoptosis
    • Kim P KM, Dutra A S, Chandrasekharappa S C, Puck J M. Genomic structure and mapping of human FADD, an intracellular mediator of lymphocyte apoptosis. Journal of Immunology. 157:1996;5461-5466.
    • (1996) Journal of Immunology , vol.157 , pp. 5461-5466
    • Kim, P.K.1    Dutra, A.S.2    Chandrasekharappa, S.C.3    Puck, J.M.4
  • 57
    • 0033047379 scopus 로고    scopus 로고
    • Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese
    • Iwata I, Nagafuchi S, Nakashima H. Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese. Diabetes. 48:1999;416-419.
    • (1999) Diabetes , vol.48 , pp. 416-419
    • Iwata, I.1    Nagafuchi, S.2    Nakashima, H.3
  • 58
    • 0030952822 scopus 로고    scopus 로고
    • Analysis of candidate genes for susceptibility to type I diabetes: A case-control and family-association study of genes on chromosome 2q31-35
    • Owerbach D, Naya F J. Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35. Diabetes. 46:1997;1069-1074.
    • (1997) Diabetes , vol.46 , pp. 1069-1074
    • Owerbach, D.1    Naya, F.J.2
  • 59
    • 0031014716 scopus 로고    scopus 로고
    • CTLA4 alanine 17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus
    • Donner H, Rau H, Walfish P G. CTLA4 alanine 17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism. 82:1997;143-146.
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 143-146
    • Donner, H.1    Rau, H.2    Walfish, P.G.3
  • 61
    • 0031890809 scopus 로고    scopus 로고
    • Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients
    • Kristiansen O P, Zamani N, Johannesen C. Linkage and association between a CD4 gene polymorphism and IDDM in Danish IDDM patients. Diabetes. 47:1998;281-283.
    • (1998) Diabetes , vol.47 , pp. 281-283
    • Kristiansen, O.P.1    Zamani, N.2    Johannesen, C.3
  • 62
    • 0030793797 scopus 로고    scopus 로고
    • Could the aetiology of IDDM be multifactorial?
    • Haverkos H W. Could the aetiology of IDDM be multifactorial? Diabetologia. 40:1997;1235-1240.
    • (1997) Diabetologia , vol.40 , pp. 1235-1240
    • Haverkos, H.W.1
  • 63
    • 0029946743 scopus 로고    scopus 로고
    • Perinatal autoimmunity in offspring of diabetic parents. The German multicenter BABY-DIAB study: Detection of humoral responses to islet antigens in early childhood
    • Roll U, Christe M R, Fuchtenbusch M. Perinatal autoimmunity in offspring of diabetic parents. The German multicenter BABY-DIAB study: detection of humoral responses to islet antigens in early childhood. Diabetes. 45:1996;967-973.
    • (1996) Diabetes , vol.45 , pp. 967-973
    • Roll, U.1    Christe, M.R.2    Fuchtenbusch, M.3
  • 64
    • 0342591874 scopus 로고    scopus 로고
    • Diabetologia. 41:1998;1115-1156.
    • (1998) Diabetologia , vol.41 , pp. 1115-1156
  • 65
    • 0026623232 scopus 로고
    • A fifty year follow up of congenital rubella
    • McIntosh E DG, Menser M A. A fifty year follow up of congenital rubella. Lancet. 340:1993;414-415.
    • (1993) Lancet , vol.340 , pp. 414-415
    • McIntosh, E.D.1    Menser, M.A.2
  • 66
    • 0028791239 scopus 로고
    • Indications that maternal Coxsackie B virus infection during pregnancy is a risk factor for childhood onset IDDM
    • Dahlquist C G, Frisk G, Ivarsson S. Indications that maternal Coxsackie B virus infection during pregnancy is a risk factor for childhood onset IDDM. Diabetologia. 38:1995;1371-1373.
    • (1995) Diabetologia , vol.38 , pp. 1371-1373
    • Dahlquist, C.G.1    Frisk, G.2    Ivarsson, S.3
  • 67
    • 0027436654 scopus 로고
    • Early introduction of dairy products associated with increased risk of IDDM in Finnish children
    • Virtanen S M, Rasanen L, Ylonen M. Early introduction of dairy products associated with increased risk of IDDM in Finnish children. Diabetes. 42:1993;1786-1790.
    • (1993) Diabetes , vol.42 , pp. 1786-1790
    • Virtanen, S.M.1    Rasanen, L.2    Ylonen, M.3
  • 69
    • 0031957644 scopus 로고    scopus 로고
    • Onset of Type 1 diabetes mellitus in infancy after enterovirus infections
    • Lonnrot M, Knip M, Roivainen M. Onset of Type 1 diabetes mellitus in infancy after enterovirus infections. Diabetic Medicine. 15:1997;431-434.
    • (1997) Diabetic Medicine , vol.15 , pp. 431-434
    • Lonnrot, M.1    Knip, M.2    Roivainen, M.3
  • 70
    • 0027186106 scopus 로고    scopus 로고
    • The possible link between insulin dependent diabetes and dietary cows milk
    • Dosch H M. The possible link between insulin dependent diabetes and dietary cows milk. Clinical Biochemistry. 26:1997;307-308.
    • (1997) Clinical Biochemistry , vol.26 , pp. 307-308
    • Dosch, H.M.1
  • 71
    • 0031967886 scopus 로고    scopus 로고
    • Putative environmental factors in type 1 diabetes
    • Akerblom H, Knip M. Putative environmental factors in type 1 diabetes. Diabetes Metabolism Reviews. 41:1998;31-67.
    • (1998) Diabetes Metabolism Reviews , vol.41 , pp. 31-67
    • Akerblom, H.1    Knip, M.2
  • 72
    • 0031867425 scopus 로고    scopus 로고
    • Cellular immune response to b casein: Elevated but not specific for individuals with type 1 diabetes mellitus
    • Ellis T M, Ottendorfer E, Jodoin E. Cellular immune response to b casein: elevated but not specific for individuals with type 1 diabetes mellitus. Diabetologia. 41:1998;731-735.
    • (1998) Diabetologia , vol.41 , pp. 731-735
    • Ellis, T.M.1    Ottendorfer, E.2    Jodoin, E.3
  • 73
    • 0031906173 scopus 로고    scopus 로고
    • Significance of cow's milk protein antibodies as a risk factor for childhood IDDM: Interactions with dietary cow's milk intake and HLA-DQB1 genotype
    • Saukkonen T, Virtanene S M, Karppinen M. Significance of cow's milk protein antibodies as a risk factor for childhood IDDM: interactions with dietary cow's milk intake and HLA-DQB1 genotype. Diabetologia. 41:1998;72-78.
    • (1998) Diabetologia , vol.41 , pp. 72-78
    • Saukkonen, T.1    Virtanene, S.M.2    Karppinen, M.3
  • 74
    • 0032005163 scopus 로고    scopus 로고
    • Protective and destructive effects of microbial infection in insulin-dependent diabetes mellitus
    • Singh B, Prange S, Jevnikar A M. Protective and destructive effects of microbial infection in insulin-dependent diabetes mellitus. Seminars in Immunology. 10:1998;79-86.
    • (1998) Seminars in Immunology , vol.10 , pp. 79-86
    • Singh, B.1    Prange, S.2    Jevnikar, A.M.3
  • 76
    • 0030840944 scopus 로고    scopus 로고
    • A human endogenous retroviral superantigen as candidate autoimmune gene in type 1 diabetes
    • Conrad B, Weldmann E, Trucco G. A human endogenous retroviral superantigen as candidate autoimmune gene in type 1 diabetes. Cell. 90:1997;303-313.
    • (1997) Cell , vol.90 , pp. 303-313
    • Conrad, B.1    Weldmann, E.2    Trucco, G.3
  • 77
    • 0027519645 scopus 로고    scopus 로고
    • Prevention of autoimmune type 1 diabetes by CD4+ suppressor cells in superantigen-treated non-obese diabetic mice
    • Kawamura T, Nagata M, Utsugi T M, Yoon J W. Prevention of autoimmune type 1 diabetes by CD4+ suppressor cells in superantigen-treated non-obese diabetic mice. Journal of Immunology. 151:1997;4362-4370.
    • (1997) Journal of Immunology , vol.151 , pp. 4362-4370
    • Kawamura, T.1    Nagata, M.2    Utsugi, T.M.3    Yoon, J.W.4
  • 78
    • 0032908808 scopus 로고    scopus 로고
    • IDDM patients neither show humoral reactivities against endogenous retroviral envelope protein nor do they differ in retroviral mRNA expression from healthy relatives or normal individuals
    • Badenhoop K, Donner H, Neumann J. IDDM patients neither show humoral reactivities against endogenous retroviral envelope protein nor do they differ in retroviral mRNA expression from healthy relatives or normal individuals. Diabetes. 48:1999;215-218.
    • (1999) Diabetes , vol.48 , pp. 215-218
    • Badenhoop, K.1    Donner, H.2    Neumann, J.3
  • 79
    • 0020039075 scopus 로고
    • Virologic, immunologic and genetic factors in insulin-dependent diabetes
    • Champsaur H F, Bottazzo G F, Bertrams J. Virologic, immunologic and genetic factors in insulin-dependent diabetes. Journal of Paediatrics. 100:1982;15-20.
    • (1982) Journal of Paediatrics , vol.100 , pp. 15-20
    • Champsaur, H.F.1    Bottazzo, G.F.2    Bertrams, J.3
  • 80
    • 0031883094 scopus 로고    scopus 로고
    • 65is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule
    • 65is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule. Diabetologia. 41:1998;40-46.
    • (1998) Diabetologia , vol.41 , pp. 40-46
    • Vreugdenhil, G.R.1    Geluk, A.2    Ottenhoff, T.M.3
  • 81
    • 0028233470 scopus 로고
    • Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 β chain
    • Parkkonnen P, Hyoty H, Ilonen J. Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 β chain. Clinical and Experimental Immunology. 95:1990;287-293.
    • (1990) Clinical and Experimental Immunology , vol.95 , pp. 287-293
    • Parkkonnen, P.1    Hyoty, H.2    Ilonen, J.3
  • 82
    • 0018886796 scopus 로고
    • Relation of antecedent illness to development of diabetes in children
    • Gamble D R. Relation of antecedent illness to development of diabetes in children. British Medical Journal. 2:1980;99-101.
    • (1980) British Medical Journal , vol.2 , pp. 99-101
    • Gamble, D.R.1
  • 83
    • 0019333556 scopus 로고
    • Islet cell antibodies in children with mumps infection
    • Helmke K, Otten A, Willems W. Islet cell antibodies in children with mumps infection. Lancet. 2:1980;211-212.
    • (1980) Lancet , vol.2 , pp. 211-212
    • Helmke, K.1    Otten, A.2    Willems, W.3
  • 84
    • 0025075154 scopus 로고
    • Human pancreatic islet cell-specific 38 kDa autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody
    • Pak C Y, Cha C Y, Rajotte R V. Human pancreatic islet cell-specific 38 kDa autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody. Diabetologia. 33:1990;569-572.
    • (1990) Diabetologia , vol.33 , pp. 569-572
    • Pak, C.Y.1    Cha, C.Y.2    Rajotte, R.V.3
  • 85
    • 0021247996 scopus 로고
    • Congenital rubella syndrome as a model for type 1 (insulin-dependent) diabetes mellitus: Increased prevalence of islet cell surface antibodies
    • Ginsberg-Fellner F, Witt M E, Yagihashi S. Congenital rubella syndrome as a model for type 1 (insulin-dependent) diabetes mellitus: increased prevalence of islet cell surface antibodies. Diabetologia. 27:1984;87-89.
    • (1984) Diabetologia , vol.27 , pp. 87-89
    • Ginsberg-Fellner, F.1    Witt, M.E.2    Yagihashi, S.3
  • 86
    • 0027316131 scopus 로고
    • Monoclonal antibody to rubella virus capid protein recognises a beta-cell antigen
    • Karounos D G, Wolinsky J S, Thomas J W. Monoclonal antibody to rubella virus capid protein recognises a beta-cell antigen. Journal of Immunology. 150:1993;3080-3085.
    • (1993) Journal of Immunology , vol.150 , pp. 3080-3085
    • Karounos, D.G.1    Wolinsky, J.S.2    Thomas, J.W.3
  • 87
    • 0027763202 scopus 로고
    • Insulin (auto) antibodies from human IDDM cross react with retroviral antigen p73
    • Hao W, Serreze D V, McCullough D K. Insulin (auto) antibodies from human IDDM cross react with retroviral antigen p73. Journal of Autoimmunity. 6:1993;787-798.
    • (1993) Journal of Autoimmunity , vol.6 , pp. 787-798
    • Hao, W.1    Serreze, D.V.2    McCullough, D.K.3


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