메뉴 건너뛰기




Volumn 126, Issue 23, 1999, Pages 5195-5205

Cardiac looping and the vertebrate left-right axis: Antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway

Author keywords

ALK2; BMP; Cardiac morphogenesis; Left right asymmetry; Smad; TGF ; Vg1; Xolloid

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; LIGAND; PHOSPHOTRANSFERASE; RECEPTOR;

EID: 0033390731     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (68)

References (70)
  • 1
    • 0030785446 scopus 로고    scopus 로고
    • The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds
    • Armes, N. A. and Smith, J. C. (1997). The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds. Development 124, 3797-3804.
    • (1997) Development , vol.124 , pp. 3797-3804
    • Armes, N.A.1    Smith, J.C.2
  • 2
    • 0033545655 scopus 로고    scopus 로고
    • FGF8 functions in the specification of the right body side of the chick
    • Boettger, T., Wittler, L. and Kessel, M. (1999). FGF8 functions in the specification of the right body side of the chick. Curr. Biol. 9, 277-280.
    • (1999) Curr. Biol. , vol.9 , pp. 277-280
    • Boettger, T.1    Wittler, L.2    Kessel, M.3
  • 4
    • 0026793735 scopus 로고
    • Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 precursors and of cysteine residues within mature TGF beta 1: Effects on secretion and bioactivity
    • Brunner, A. M., Lioubin, M. N., Marquardt, H., Malacko, A. R., Wang, W. C., Shapiro, R. A., Neubauer, M., Cook, J., Madisen, L. and Purchio, A. F. (1992). Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity. Mol. Endocrinol. 6, 1691-1700.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1691-1700
    • Brunner, A.M.1    Lioubin, M.N.2    Marquardt, H.3    Malacko, A.R.4    Wang, W.C.5    Shapiro, R.A.6    Neubauer, M.7    Cook, J.8    Madisen, L.9    Purchio, A.F.10
  • 5
    • 0024312217 scopus 로고
    • Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins
    • Brunner, A. M., Marquardt, H., Malacko, A. R., Lioubin, M. N. and Purchio, A. F. (1989). Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins. J. Biol. Chem. 264, 13660-13664.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13660-13664
    • Brunner, A.M.1    Marquardt, H.2    Malacko, A.R.3    Lioubin, M.N.4    Purchio, A.F.5
  • 7
    • 0030663881 scopus 로고    scopus 로고
    • Cellular interpretation of multiple TGF-beta signals: Intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads
    • Candia, A. F., Watabe, T., Hawley, S. H., Onichtchouk, D., Zhang, Y., Derynck, R., Niehrs, C. and Cho, K. W. (1997). Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads. Development 124, 4467-4480.
    • (1997) Development , vol.124 , pp. 4467-4480
    • Candia, A.F.1    Watabe, T.2    Hawley, S.H.3    Onichtchouk, D.4    Zhang, Y.5    Derynck, R.6    Niehrs, C.7    Cho, K.W.8
  • 8
    • 0032101098 scopus 로고    scopus 로고
    • Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer
    • Casellas, R. and Brivanlou, A. H. (1998). Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer. Dev. Biol. 198, 1-12.
    • (1998) Dev. Biol. , vol.198 , pp. 1-12
    • Casellas, R.1    Brivanlou, A.H.2
  • 9
    • 0032856523 scopus 로고    scopus 로고
    • Xenopus GDF6, a new antagonist of noggin and a partner of BMPs
    • Chang, C. and Hemmati-Brivanlou, A. (1999). Xenopus GDF6, a new antagonist of noggin and a partner of BMPs. Development 126, 3347-3357.
    • (1999) Development , vol.126 , pp. 3347-3357
    • Chang, C.1    Hemmati-Brivanlou, A.2
  • 10
    • 0031027637 scopus 로고    scopus 로고
    • A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis
    • Chang, C., Wilson, P. A., Mathews, L. S. and Hemmati-Brivanlou, A. (1997). A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development 124, 827-837.
    • (1997) Development , vol.124 , pp. 827-837
    • Chang, C.1    Wilson, P.A.2    Mathews, L.S.3    Hemmati-Brivanlou, A.4
  • 11
    • 0030667930 scopus 로고    scopus 로고
    • Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase
    • published erratum appears in Proc. Natl. Acad. Sci. USA Feb 17;95(4):1968
    • Chen, Y., Bhushan, A. and Vale, W. (1997). Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase [published erratum appears in Proc. Natl. Acad. Sci. USA Feb 17;95(4):1968]. Proc. Natl. Acad. Sci. USA 94, 12938-12943.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12938-12943
    • Chen, Y.1    Bhushan, A.2    Vale, W.3
  • 12
    • 0031712371 scopus 로고    scopus 로고
    • BMPs, Smads and metalloproteases: Extracellular and intracellular modes of negative regulation
    • Cho, K. W. and Blitz, I. L. (1998). BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation. Curr. Opin. Genet. Dev. 8, 443-449.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 443-449
    • Cho, K.W.1    Blitz, I.L.2
  • 13
    • 0029993646 scopus 로고    scopus 로고
    • Relationship between asymmetric nodal expression and the direction of embryonic turning
    • Collignon, J., Varlet, I. and Robertson, E. J. (1996). Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381, 155-158.
    • (1996) Nature , vol.381 , pp. 155-158
    • Collignon, J.1    Varlet, I.2    Robertson, E.J.3
  • 14
    • 0028180752 scopus 로고
    • A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
    • Conlon, F. L., Lyons, K. M., Takaesu, N., Barth, K. S., Kispert, A., Herrmann, B. and Robertson, E. J. (1994). A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 120, 1919-1928.
    • (1994) Development , vol.120 , pp. 1919-1928
    • Conlon, F.L.1    Lyons, K.M.2    Takaesu, N.3    Barth, K.S.4    Kispert, A.5    Herrmann, B.6    Robertson, E.J.7
  • 15
    • 0033545215 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
    • Constam, D. B. and Robertson, E. J. (1999). Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. J. Cell Biol. 144, 139-149.
    • (1999) J. Cell Biol. , vol.144 , pp. 139-149
    • Constam, D.B.1    Robertson, E.J.2
  • 16
    • 0029043838 scopus 로고
    • Linkage of cardiac left-right asymmetry and dorsal-anterior development in Xenopus
    • Danos, M. C. and Yost, H. J. (1995). Linkage of cardiac left-right asymmetry and dorsal-anterior development in Xenopus. Development 121, 1467-1474.
    • (1995) Development , vol.121 , pp. 1467-1474
    • Danos, M.C.1    Yost, H.J.2
  • 17
    • 0030578449 scopus 로고    scopus 로고
    • Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus
    • Danos, M. C. and Yost, H. J. (1996). Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. Dev. Biol. 177, 96-103.
    • (1996) Dev. Biol. , vol.177 , pp. 96-103
    • Danos, M.C.1    Yost, H.J.2
  • 19
    • 0028832707 scopus 로고
    • A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
    • Dudley, A. T., Lyons, K. M. and Robertson, E. J. (1995). A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 9, 2795-2807.
    • (1995) Genes Dev. , vol.9 , pp. 2795-2807
    • Dudley, A.T.1    Lyons, K.M.2    Robertson, E.J.3
  • 20
    • 0025324976 scopus 로고
    • The pro domain of pre-pro-transforming growth factor beta 1 when independently expressed is a functional binding protein for the mature growth factor
    • Gentry, L. E. and Nash, B. W. (1990). The pro domain of pre-pro-transforming growth factor beta 1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29, 6851-6857.
    • (1990) Biochemistry , vol.29 , pp. 6851-6857
    • Gentry, L.E.1    Nash, B.W.2
  • 21
    • 0028170038 scopus 로고
    • Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
    • Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A. (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.
    • (1994) Cell , vol.79 , pp. 169-179
    • Graff, J.M.1    Thies, R.S.2    Song, J.J.3    Celeste, A.J.4    Melton, D.A.5
  • 22
    • 0025373853 scopus 로고
    • Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly
    • Gray, A. M. and Mason, A. J. (1990). Requirement for activin A and transforming growth factor-beta 1 pro-regions in homodimer assembly. Science 247, 1328-1330.
    • (1990) Science , vol.247 , pp. 1328-1330
    • Gray, A.M.1    Mason, A.J.2
  • 24
    • 0029028648 scopus 로고
    • Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system
    • Hazama, M., Aono, A., Ueno, N. and Fujisawa, Y. (1995) Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem. Biophys. Res. Commun. 209, 859-866.
    • (1995) Biochem. Biophys. Res. Commun. , vol.209 , pp. 859-866
    • Hazama, M.1    Aono, A.2    Ueno, N.3    Fujisawa, Y.4
  • 25
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin, C. H., Miyazono, K. and ten Dijke, P. (1997). TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 26
    • 0029148342 scopus 로고
    • Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP-2 and BMP-4
    • Hemmati-Brivanlou, A. and Thomsen, G. H. (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17, 78-89.
    • (1995) Dev. Genet. , vol.17 , pp. 78-89
    • Hemmati-Brivanlou, A.1    Thomsen, G.H.2
  • 27
    • 0030929040 scopus 로고    scopus 로고
    • The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness
    • Heymer, J., Kuehn, M. and Ruther, U. (1997). The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness. Mech. Dev. 66, 5-11.
    • (1997) Mech. Dev. , vol.66 , pp. 5-11
    • Heymer, J.1    Kuehn, M.2    Ruther, U.3
  • 28
    • 0033559209 scopus 로고    scopus 로고
    • Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus
    • Hoodless, P. A., Tsukazaki, T., Nishimatsu, S., Attisano, L., Wrana, J. L. and Thomsen, G. H. (1999). Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus. Dev. Biol. 207, 364-379.
    • (1999) Dev. Biol. , vol.207 , pp. 364-379
    • Hoodless, P.A.1    Tsukazaki, T.2    Nishimatsu, S.3    Attisano, L.4    Wrana, J.L.5    Thomsen, G.H.6
  • 29
    • 0029854744 scopus 로고    scopus 로고
    • Initiation of vertebrate left-right axis formation by maternal Vg1
    • Hyatt, B. A., Lohr, J. L. and Yost, H. J. (1996). Initiation of vertebrate left-right axis formation by maternal Vg1. Nature 384, 62-65.
    • (1996) Nature , vol.384 , pp. 62-65
    • Hyatt, B.A.1    Lohr, J.L.2    Yost, H.J.3
  • 30
    • 0032478546 scopus 로고    scopus 로고
    • The left-right coordinator: The role of Vg1 in organizing left-right axis formation
    • Hyatt, B. A. and Yost, H. J. (1998). The left-right coordinator: the role of Vg1 in organizing left-right axis formation. Cell 93, 37-46.
    • (1998) Cell , vol.93 , pp. 37-46
    • Hyatt, B.A.1    Yost, H.J.2
  • 31
    • 0031051863 scopus 로고    scopus 로고
    • Control of vertebrate left-right asymmetry by a snail-related zinc finger gene
    • Isaac, A., Sargent, M. G. and Cooke, J. (1997). Control of vertebrate left-right asymmetry by a snail-related zinc finger gene. Science 275, 1301-1304.
    • (1997) Science , vol.275 , pp. 1301-1304
    • Isaac, A.1    Sargent, M.G.2    Cooke, J.3
  • 32
    • 0029862206 scopus 로고    scopus 로고
    • Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo
    • Israel, D. I., Nove, J., Kerns, K. M., Kaufman, R. J., Rosen, V., Cox, K. A. and Wozney, J. M. (1996). Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo. Growth Factors 13, 291-300.
    • (1996) Growth Factors , vol.13 , pp. 291-300
    • Israel, D.I.1    Nove, J.2    Kerns, K.M.3    Kaufman, R.J.4    Rosen, V.5    Cox, K.A.6    Wozney, J.M.7
  • 33
    • 0023916662 scopus 로고
    • The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos
    • Kao, K. R. and Elinson, R. P. (1988). The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos. Dev. Biol. 127, 64-77.
    • (1988) Dev. Biol. , vol.127 , pp. 64-77
    • Kao, K.R.1    Elinson, R.P.2
  • 34
    • 0029001002 scopus 로고
    • Induction of dorsal mesoderm by soluble, mature Vg1 protein
    • Kessler, D. S. and Melton, D. A. (1995). Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121, 2155-2164.
    • (1995) Development , vol.121 , pp. 2155-2164
    • Kessler, D.S.1    Melton, D.A.2
  • 35
    • 0030560916 scopus 로고    scopus 로고
    • The vertebrate organizer -structure and molecules
    • Lemaire, P. and Kodjabachian, L. (1996). The vertebrate Organizer -structure and molecules. Trends Genet. 12, 525-531.
    • (1996) Trends Genet. , vol.12 , pp. 525-531
    • Lemaire, P.1    Kodjabachian, L.2
  • 36
    • 0029089617 scopus 로고
    • A molecular pathway determining left-right asymmetry in chick embryogenesis
    • Levin, M., Johnson, R. L., Stern, C. D., Kuehn, M. and Tabin, C. (1995). A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82, 803-814.
    • (1995) Cell , vol.82 , pp. 803-814
    • Levin, M.1    Johnson, R.L.2    Stern, C.D.3    Kuehn, M.4    Tabin, C.5
  • 37
    • 0031792764 scopus 로고    scopus 로고
    • Evolutionary conservation of mechanisms upstream of asymmetric nodal expression: Reconciling chick and Xenopus
    • Levin, M. and Mercola, M. (1998a). Evolutionary conservation of mechanisms upstream of asymmetric Nodal expression: reconciling chick and Xenopus. Dev. Genet. 23, 185-193.
    • (1998) Dev. Genet. , vol.23 , pp. 185-193
    • Levin, M.1    Mercola, M.2
  • 38
    • 0032212639 scopus 로고    scopus 로고
    • Gap junctions are involved in the early generation of left-right asymmetry
    • Levin, M. and Mercola, M. (1998b). Gap junctions are involved in the early generation of left-right asymmetry. Dev. Biol. 203, 90-105.
    • (1998) Dev. Biol. , vol.203 , pp. 90-105
    • Levin, M.1    Mercola, M.2
  • 39
    • 0031238780 scopus 로고    scopus 로고
    • Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo
    • Levin, M., Pagan, S., Roberts, D. J., Cooke, J., Kuehn, M. R. and Tabin, C. J. (1997). Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol. 189, 57-67.
    • (1997) Dev. Biol. , vol.189 , pp. 57-67
    • Levin, M.1    Pagan, S.2    Roberts, D.J.3    Cooke, J.4    Kuehn, M.R.5    Tabin, C.J.6
  • 40
    • 0032493897 scopus 로고    scopus 로고
    • The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals
    • Logan, M., Pagan-Westphal, S. M., Smith, D. M., Paganessi, L. and Tabin, C. J. (1998). The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell 94, 307-317.
    • (1998) Cell , vol.94 , pp. 307-317
    • Logan, M.1    Pagan-Westphal, S.M.2    Smith, D.M.3    Paganessi, L.4    Tabin, C.J.5
  • 41
    • 0031774318 scopus 로고    scopus 로고
    • Maintenance of asymmetric nodal expression in Xenopus laevis
    • Lohr, J. L., Danos, M. C., Groth, T. W. and Yost, H. J. (1998). Maintenance of asymmetric nodal expression in Xenopus laevis. Dev. Genet. 23, 194-202.
    • (1998) Dev. Genet. , vol.23 , pp. 194-202
    • Lohr, J.L.1    Danos, M.C.2    Groth, T.W.3    Yost, H.J.4
  • 42
    • 0030907502 scopus 로고    scopus 로고
    • Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
    • Lohr, J. L., Danos, M. C. and Yost, H. J. (1997). Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. Development 124, 1465-1472.
    • (1997) Development , vol.124 , pp. 1465-1472
    • Lohr, J.L.1    Danos, M.C.2    Yost, H.J.3
  • 44
    • 0032475884 scopus 로고    scopus 로고
    • Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
    • Macias-Silva, M., Hoodless, P. A., Tang, S. J., Buchwald, M. and Wrana, J. L. (1998). Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J. Biol. Chem. 273, 25628-25636.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25628-25636
    • Macias-Silva, M.1    Hoodless, P.A.2    Tang, S.J.3    Buchwald, M.4    Wrana, J.L.5
  • 46
    • 0033575364 scopus 로고    scopus 로고
    • Differences in left-right axis pathways in mouse and chick: Functions of FGF8 and SHH
    • Meyers, E. N. and Martin, G. R. (1999). Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. Science 285, 403-406.
    • (1999) Science , vol.285 , pp. 403-406
    • Meyers, E.N.1    Martin, G.R.2
  • 47
    • 0031939483 scopus 로고    scopus 로고
    • Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning
    • Nakayama, T., Snyder, M. A., Grewal, S. S., Tsuneizumi, K., Tabata, T. and Christian, J. L. (1998). Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning. Development 125, 857-867.
    • (1998) Development , vol.125 , pp. 857-867
    • Nakayama, T.1    Snyder, M.A.2    Grewal, S.S.3    Tsuneizumi, K.4    Tabata, T.5    Christian, J.L.6
  • 48
    • 0032102668 scopus 로고    scopus 로고
    • Ventral mesoderm induction and patterning by bone morphogenetic protein heterodimers in Xenopus embryos
    • Nishimatsu, S. and Thomsen, G. H. (1998). Ventral mesoderm induction and patterning by bone morphogenetic protein heterodimers in Xenopus embryos. Mech. Dev. 74, 75-88.
    • (1998) Mech. Dev. , vol.74 , pp. 75-88
    • Nishimatsu, S.1    Thomsen, G.H.2
  • 49
    • 0032478497 scopus 로고    scopus 로고
    • The transfer of left-right positional information during chick embryogenesis
    • Pagan-Westphal, S. M. and Tabin, C. J. (1998). The transfer of left-right positional information during chick embryogenesis. Cell 93, 25-35.
    • (1998) Cell , vol.93 , pp. 25-35
    • Pagan-Westphal, S.M.1    Tabin, C.J.2
  • 50
    • 0030665807 scopus 로고    scopus 로고
    • Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity
    • Piccolo, S., Agius, E., Lu, B., Goodman, S., Dale, L. and De Robertis, E. M. (1997). Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell 91, 407-416.
    • (1997) Cell , vol.91 , pp. 407-416
    • Piccolo, S.1    Agius, E.2    Lu, B.3    Goodman, S.4    Dale, L.5    De Robertis, E.M.6
  • 51
    • 0032493860 scopus 로고    scopus 로고
    • Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
    • Piedra, M. E., Icardo, J. M., Albajar, M., Rodriguez-Rey, J. C. and Ros, M. A. (1998). Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94, 319-324.
    • (1998) Cell , vol.94 , pp. 319-324
    • Piedra, M.E.1    Icardo, J.M.2    Albajar, M.3    Rodriguez-Rey, J.C.4    Ros, M.A.5
  • 52
    • 0031769527 scopus 로고    scopus 로고
    • Molecular mechanisms of vertebrate left-right development
    • Ramsdell, A. F. and Yost, H. J. (1998). Molecular mechanisms of vertebrate left-right development. Trends Genet. 14, 459-465.
    • (1998) Trends Genet. , vol.14 , pp. 459-465
    • Ramsdell, A.F.1    Yost, H.J.2
  • 53
    • 0343228814 scopus 로고    scopus 로고
    • Cardiac looping and the left-right axis: Integrating morphological, molecular, and genetic analyses of vertebrate left-right asymmetry
    • (ed. R. J. Tomanek and R. B. Runyun). Greenwich, CT: JAI Press. In press
    • Ramsdell, A. F. and Yost, H. J. (1999). Cardiac looping and the left-right axis: integrating morphological, molecular, and genetic analyses of vertebrate left-right asymmetry. In Development of the Cardiovascular System, vol. 1 (ed. R. J. Tomanek and R. B. Runyun). Greenwich, CT: JAI Press. (In press.)
    • (1999) Development of the Cardiovascular System , vol.1
    • Ramsdell, A.F.1    Yost, H.J.2
  • 54
    • 0032528389 scopus 로고    scopus 로고
    • Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry
    • Rebagliati, M. R., Toyama, R., Fricke, C., Haffter, P. and Dawid, I. B. (1998a). Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Devr. Biol. 199, 261-272.
    • (1998) Devr. Biol. , vol.199 , pp. 261-272
    • Rebagliati, M.R.1    Toyama, R.2    Fricke, C.3    Haffter, P.4    Dawid, I.B.5
  • 55
  • 57
    • 0030869668 scopus 로고    scopus 로고
    • Functional differences among Xenopus nodal-related genes in left-right axis determination
    • Sampath, K., Cheng, A. M., Frisch, A. and Wright, C. V. (1997). Functional differences among Xenopus nodal-related genes in left-right axis determination. Development 124, 3293-3302.
    • (1997) Development , vol.124 , pp. 3293-3302
    • Sampath, K.1    Cheng, A.M.2    Frisch, A.3    Wright, C.V.4
  • 59
    • 0031081234 scopus 로고    scopus 로고
    • Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry
    • Smith, S. M., Dickman, E. D., Thompson, R. P., Sinning, A. R., Wunsch, A. M. and Markwald, R. R. (1997). Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry. Dev. Biol. 182, 162-171.
    • (1997) Dev. Biol. , vol.182 , pp. 162-171
    • Smith, S.M.1    Dickman, E.D.2    Thompson, R.P.3    Sinning, A.R.4    Wunsch, A.M.5    Markwald, R.R.6
  • 60
    • 0032566611 scopus 로고    scopus 로고
    • Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors
    • Souchelnytskyi, S., Nakayama, T., Nakao, A., Moren, A., Heldin, C. H., Christian, J. L. and ten Dijke, P. (1998). Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors. J. Biol. Chem. 273, 25364-25370.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25364-25370
    • Souchelnytskyi, S.1    Nakayama, T.2    Nakao, A.3    Moren, A.4    Heldin, C.H.5    Christian, J.L.6    Ten Dijke, P.7
  • 62
    • 0031239298 scopus 로고    scopus 로고
    • Regulation of epidermal induction by BMP2 and BMP7 signaling
    • Suzuki, A., Kaneko, E., Ueno, N. and Hemmati-Brivanlou, A. (1997b). Regulation of epidermal induction by BMP2 and BMP7 signaling. Dev. Biol. 189, 112-122.
    • (1997) Dev. Biol. , vol.189 , pp. 112-122
    • Suzuki, A.1    Kaneko, E.2    Ueno, N.3    Hemmati-Brivanlou, A.4
  • 63
    • 0032943366 scopus 로고    scopus 로고
    • Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction
    • Thisse, C. and Thisse, B. (1999). Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development 126, 229-240.
    • (1999) Development , vol.126 , pp. 229-240
    • Thisse, C.1    Thisse, B.2
  • 64
    • 0032529159 scopus 로고    scopus 로고
    • Smads and early developmental signaling by the TGFbeta superfamily
    • Whitman, M. (1998). Smads and early developmental signaling by the TGFbeta superfamily. Genes Dev. 12, 2445-2462.
    • (1998) Genes Dev. , vol.12 , pp. 2445-2462
    • Whitman, M.1
  • 65
    • 0027408040 scopus 로고
    • Mullerian inhibiting substance requires its N-terminal domain for maintenance of biological activity, a novel finding within the transforming growth factor-beta superfamily
    • Wilson, C. A., di Clemente, N., Ehrenfels, C., Pepinsky, R. B., Josso, N., Vigier, B. and Cate, R. L. (1993). Mullerian inhibiting substance requires its N-terminal domain for maintenance of biological activity, a novel finding within the transforming growth factor-beta superfamily. Mol. Endocrinol. 7, 247-257.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 247-257
    • Wilson, C.A.1    Di Clemente, N.2    Ehrenfels, C.3    Pepinsky, R.B.4    Josso, N.5    Vigier, B.6    Cate, R.L.7
  • 66
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
    • Winnier, G., Blessing M., Labosky, P. A. and Hogan, B. L. (1995). Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-2116.
    • (1995) Genes Dev. , vol.9 , pp. 2105-2116
    • Winnier, G.1    Blessing, M.2    Labosky, P.A.3    Hogan, B.L.4
  • 68
    • 0032493866 scopus 로고    scopus 로고
    • Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry
    • Yoshinka, H., Meno, C., Koshiha, K., Sugihara, M., Itoh, H., Ishimaru, Y., Inoue, T., Ohuchi, H., Semina, E. V., Murray, J. C. et al. (1998). Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell 94, 299-305.
    • (1998) Cell , vol.94 , pp. 299-305
    • Yoshinka, H.1    Meno, C.2    Koshiha, K.3    Sugihara, M.4    Itoh, H.5    Ishimaru, Y.6    Inoue, T.7    Ohuchi, H.8    Semina, E.V.9    Murray, J.C.10
  • 69
    • 0033523290 scopus 로고    scopus 로고
    • Diverse initiation in a conserved left-right pathway?
    • Yost, H. J. (1999). Diverse initiation in a conserved left-right pathway? Curr. Opin. Genet. Dev. 9, 422-426.
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 422-426
    • Yost, H.J.1
  • 70
    • 0029850112 scopus 로고    scopus 로고
    • Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
    • Zhang, H. and Bradley, A. (1996). Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122, 2977-2986.
    • (1996) Development , vol.122 , pp. 2977-2986
    • Zhang, H.1    Bradley, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.