Xenopus GDF6, a new antagonist of noggin and a partner of BMPs

Development

Volumn 126, Issue 15, 1999, Pages 3347-3357

  Chang, Chenbei ^a   Hemmati Brivanlou, Ali ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

BMP; Epidermal inducer; GDF6; Neural inducer; Noggin

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FOLLISTATIN; LIGAND; SECRETORY PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ARTICLE; CELL FATE; DEVELOPMENTAL GENETICS; ECTODERM; EMBRYO; EMBRYO PATTERN FORMATION; EPIDERMIS CELL; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; DNA PRIMERS; EPIDERMIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH SUBSTANCES; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; NERVOUS SYSTEM; PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFORMING GROWTH FACTOR BETA; XENOPUS;

EID: 0032856523     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Bouwmeester, T., Kim, S.-H., Sasai, V., Lu, B. and DeRobertis, E. M. (1996). Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382, 595-601.
2. Chang, C., Wilson, P. A., Mathews, L. S. and Hemmati-Brivanlou, A. (1997). A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development 124, 827-837.
3. Chang, C. and Hemmati-Brivanlou, A. (1998). Cell fate determination in embryonic ectoderm. J. Neurobiol. 36, 128-151.
4. Dong, J., Albertini, D. F., Nishimori, K., Kumar, T. R., Lu, N. and Matzuk, M. M. (1996). Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature 383, 531-535.
5. Fainsod, A., Deissler, K., Yelin, R., Marom, K., Epstein, M., Pillemer, G., Steinbeisser, H. and Blum, M. (1997). The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4. Mech. Dev. 63, 39-50.
6. Fainsod, A., Steinbeisser, H. and De Robertis, E. M. (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13, 5015-5025.
7. Gawantka, V., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C. (1995). Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. EMBO J 14, 6268-6279.
8. Godsave, S. F. and Slack, J. M. W. (1989). Clonal analysis of mesoderm induction in Xenopus laevis. Dev. Biol. 134, 486-490.
9. Grunz, H. and Tacke, L. (1989). Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ. Dev. 28, 211-218.
10. Hansen, C. S., Marion, C. D., Steele, K., George, S. and Smith, W.C. (1997). Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3. Development 124, 483-492.
11. Harland, R. M. (1991). In situ hybridization: an improved wholemount method for Xenopus embryos. Methods Cell Biology 36, 675-685.
12. Hawley, S. H. B, Wunnenberg-Stapleton, K., Hashimoto, C., Laurent, M. N., Watabe, T., Blumberg, B. W. and Cho, K. W. Y. (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev. 9, 2923-2935.
13. Hemmati-Brivanlou, A. and Harland, R. M. (1989). Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development 106, 611-617.
14. Hemmati-Brivanlou, A., de la Torre, J. R., Holt, C. and Harland, R. M. (1991). Cephalic expression and molecular characterization of Xenopus En-2. Development 111, 715-724.
15. Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A. (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.
16. Hemmati-Brivanlou, A. and Melton, D. A. (1994). Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281.
17. Hemmati-Brivanlou, A. and Thomsen, G. H. (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet. 17, 78-89.
18. Hsu, D. R., Economides, A. N., Wang, X., Eimon, P. M. and Harland, R. M. (1998). The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell 1, 673-683.
19. Iemura, S., Yamamoto, T. S., Takagi, C., Uchiyama, H., Natsume, T., Shimasaki, S., Sugino, H. and Ueno, N. (1998). Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc. Natl. Acad. Sci. USA 95, 9337-9342.
20. Jonas, E., Sargent, T. D. and Dawid, I. B. (1985). Epidermal keratin gene expressed in embryos of Xenopus laevis. Proc. Natl. Acad. Sci. USA 82, 5413-5417.
21. Kessler, D. S. and Melton, D. A. (1995). Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121, 2155-2164.
22. Kintner, C. R. and Melton, D. A. (1987). Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. Development 99, 311-325.
23. Lamb, T. M., Knecht, A. K., Smith, W. C., Stachel, S. E., Economides, A. N., Stahl, N., Yancopolous, G. D. and Harland, R. M. (1993). Neural induction by the secreted polypeptide noggin. Sci. 262, 713-718.
24. Lee, K. J., Mendelsohn, M. and Jessell, T. M. (1998) Neuronal patterning by BMPs: a requirement tor GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes & Dev. 12, 3394-3407.
25. Liem Jr., K. F., Tremml, G. and Jessell, T. M. (1997). A role for the roof plate and its resident TGFβ-related proteins in neuronal patterning in the dorsal spinal cord. Cell 91, 127-138.
26. Lowry, O.H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951). Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275.
27. Marchant, L., Linker, C., Ruiz, P., Guerrero, N. and Mayor, R. (1998). The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient. Dev. Biol. 198, 319-329.
28. Mariani, F. V. and Harland, R. M. (1998). XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue. Development 125, 5019-5031.
29. Morgan, R. and Sargent, M. G. (1997). The role in neural patterning of translation initiation factor eIF4AII; induction of neural fold genes. Development 124, 2751-2760.
30. Nakata, K., Nagai, T., Aruga, J. and Mikoshiba, K. (1997). Xenopus Zic3, a primary regulator both in neural and neural crest development. Proc. Natl. Acad. Sci. USA 94, 11980-11985.
31. Nieto, M. A., Sargent, M. G., Wilkinson, D. G. and Cooke, J. (1994). Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Sci. 264, 835-839.
32. Nieuwkoop, P. D. and Faber, J. (1967). Normal table of Xenopus laevis (Daudin). North-Holland, Amsterdam.
33. Onichtchouk, D., Gawantka, V., Dosch, R., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C. (1996). The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling dorsoventral patterning of Xenopus mesoderm. Development 122, 3045-3053.
34. Piccolo, S., Sasai, Y., Lu, B. and De Robertis, E. M. (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589-598.
35. Richter, K., Good, P. J. and Dawid, I. B. (1990). A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein. New Biol. 2, 556-565.
36. Rissi, M., Wittbrodt, J., Delot, E., Naegeli, M. and Rosa, F. M. (1995). Zebrafish Radar: a new member of the TGF-β superfamily defines dorsal regions of the neural plate and the embryonic retina. Mech. Dev. 49, 223-234.
37. Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M. (1994). Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
38. Sasai, Y., Lu, B., Steinbeisser, H. and De Robertis, E. M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
39. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Herrmann, B. G. (1991a). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
40. Smith, L. D., Xu, W. and Varnold, R. L. (1991b). Oogenesis and oocyte isolation. Methods in Cell Biology 36, 45-60.
41. Smith, W. C. and Harland, R. M. (1992). Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840.
42. Smith, W. C., McKendry, R., Ribisi Jr., S. and Harland, R. M. (1995). A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82, 37-46.
43. Storm, E. E., Huynh, T. V., Copeland, N. G., Jenkins, N. A., Kingsley, D. M. and Lee, S.-J. (1994). Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily. Nature 368, 639-643.
44. Storm, E. E. and Kingsley, D. M. (1996). Joint patterning detects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family. Development 122, 3969-3979.
45. Suzuki, A., Shioda, N. and Ueno, N. (1995). Bone morphogenetic protein acts as a ventral mesoderm modifier in early Xenopus embryos. Dev. Growth Differ. 37, 581-588.
46. Suzuki, A., Kaneko, E., Ueno, N. and Hemmati-Brivanlou, A. (1997a). Regulation of epidermal induction by BMP2 and BMP7 signaling. Dev. Biol. 189, 112-122.
47. Suzuki, A., Kaneko, E., Maeda, J. and Ueno, N. (1997b). Mesoderm induction by BMP-4 and -7 heterodimers. Biochem. Biophys. Res. Commun. 232, 153-156.
48. Weeks, D. L. and Melton, D. A. (1987). A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-β. Cell 51, 861-867.
49. Whitman, M. (1998). Smads and early developmental signaling by the TGFβ superfamily. Genes Dev. 12, 2445-2462.
50. Wilson, P. A. and Hemmati-Brivanlou, A. (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.
51. Wilson, P. A. and Hemmati-Brivanlou, A. (1997). Vertebrate neural induction: inducers, inhibitors, and a new synthesis. Neuron 18, 699-710.
52. Wilson, P. A., Lagna, G., Suzuki, A. and Hemmati-Brivanlou, A. (1997). Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development 124, 3177-3184.
53. Xu, R. H., Kim, J., Taira, M., Zhan, S., Sredni, D. and Kung, H. F. (1995). A dominant-negative bone morphogenetic protein 4 receptor causes neuralization in Xenopus ectoderm. Biochem. Biophys. Res. Commun. 212, 212-219.
54. Yamashita, H., ten Dijke, P., Huylebroeck, D., Sampath, T. K., Andries, M., Smith, J. C., Heldin, C.-H. and Miyazono, K. (1995). Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J. Cell Biol. 130, 217-226.
55. Zimmerman, L. B., De Jesus-Escobar, J. M. and Harland, R. M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.