-
2
-
-
0030627339
-
Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions
-
Crespi CL, Penman BW (1997) Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions. Adv Pharmacol 43: 171-188
-
(1997)
Adv Pharmacol
, vol.43
, pp. 171-188
-
-
Crespi, C.L.1
Penman, B.W.2
-
3
-
-
8944256082
-
Nomenclature for human CYP2D6 alleles
-
Daly AK, Brockmoller J, Broly F, Eichelbaum M, Evans WE, Gonzalez FJ, Huang J-D, Idle JR, Ingelman-Sundberg M, Ishizaki T, Jacqz-Aigrain E, Meyer UA, Nebert DW, Steen VM, Wolf CR, Zanger UM (1996) Nomenclature for human CYP2D6 alleles. Pharmacogenetics 6: 193-201
-
(1996)
Pharmacogenetics
, vol.6
, pp. 193-201
-
-
Daly, A.K.1
Brockmoller, J.2
Broly, F.3
Eichelbaum, M.4
Evans, W.E.5
Gonzalez, F.J.6
Huang, J.-D.7
Idle, J.R.8
Ingelman-Sundberg, M.9
Ishizaki, T.10
Jacqz-Aigrain, E.11
Meyer, U.A.12
Nebert, D.W.13
Steen, V.M.14
Wolf, C.R.15
Zanger, U.M.16
-
4
-
-
0029048772
-
The CYP2 A gene subfamily: Species differences, regulation, catalytic activities and role in chemical carcinogenesis
-
Fernandez-Salguero P, Gonzalez FJ (1995) The CYP2 A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis. Pharmacogenetics 5: 123-128
-
(1995)
Pharmacogenetics
, vol.5
, pp. 123-128
-
-
Fernandez-Salguero, P.1
Gonzalez, F.J.2
-
5
-
-
0029099107
-
A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
-
Fernandez-Salguero P, Hoffman SMG, Cholerton S, Mohrenweiser H, Raunio H, Rautio A, Pelkonen O, Huang J-D, Evans WE, Idle JR, Gonzalez FJ (1995) A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet 57: 651-660
-
(1995)
Am J Hum Genet
, vol.57
, pp. 651-660
-
-
Fernandez-Salguero, P.1
Hoffman, S.M.G.2
Cholerton, S.3
Mohrenweiser, H.4
Raunio, H.5
Rautio, A.6
Pelkonen, O.7
Huang, J.-D.8
Evans, W.E.9
Idle, J.R.10
Gonzalez, F.J.11
-
6
-
-
0030588661
-
Recombinant DNA technology as an investigative tool in drug metabolism research
-
Friedberg T, Wolf CR (1996) Recombinant DNA technology as an investigative tool in drug metabolism research. Adv Drug Deliv Rev 22: 187-213
-
(1996)
Adv Drug Deliv Rev
, vol.22
, pp. 187-213
-
-
Friedberg, T.1
Wolf, C.R.2
-
7
-
-
0002254766
-
Analysis and characterization of enzymes
-
Hayes AW (ed). Raven Press, New York
-
Guengerich FP (1994) Analysis and characterization of enzymes. In: Hayes AW (ed) Principles and methods of toxicology. Raven Press, New York, pp 1259-1313
-
(1994)
Principles and Methods of Toxicology
, pp. 1259-1313
-
-
Guengerich, F.P.1
-
8
-
-
0020028678
-
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
Guengerich FP, Wang P, Davidson NK (1982) Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21: 1698-1706
-
(1982)
Biochemistry
, vol.21
, pp. 1698-1706
-
-
Guengerich, F.P.1
Wang, P.2
Davidson, N.K.3
-
9
-
-
0031003669
-
Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4′-hydroxylation activities in livers of Japanese and Caucasian populations
-
Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T (1997) Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4′-hydroxylation activities in livers of Japanese and Caucasian populations. Pharmacogenetics 7: 103-113
-
(1997)
Pharmacogenetics
, vol.7
, pp. 103-113
-
-
Inoue, K.1
Yamazaki, H.2
Imiya, K.3
Akasaka, S.4
Guengerich, F.P.5
Shimada, T.6
-
10
-
-
0031958269
-
Linkage between the distribution of mutations in the CYP2C18 and CYP2C19 genes in Japanese and Caucasians
-
Inoue K, Yamazaki H, Shimada T (1998) Linkage between the distribution of mutations in the CYP2C18 and CYP2C19 genes in Japanese and Caucasians. Xenobiotica 28: 403-411
-
(1998)
Xenobiotica
, vol.28
, pp. 403-411
-
-
Inoue, K.1
Yamazaki, H.2
Shimada, T.3
-
11
-
-
0019741894
-
Production and application of antibodies to rat liver cytochrome P-450
-
Kaminsky LS, Fasco MJ, Guengerich FP (1981) Production and application of antibodies to rat liver cytochrome P-450. Methods Enzymol 74: 262-272
-
(1981)
Methods Enzymol
, vol.74
, pp. 262-272
-
-
Kaminsky, L.S.1
Fasco, M.J.2
Guengerich, F.P.3
-
13
-
-
0030885491
-
A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes
-
Messina ES, Tyndale RF, Sellers EM (1997) A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes. J Pharmacol Exp Ther 282: 1608-1614
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 1608-1614
-
-
Messina, E.S.1
Tyndale, R.F.2
Sellers, E.M.3
-
14
-
-
0030435329
-
( + )-Cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes
-
Nunoya K, Yokoi T, Kimura K, Kodama T, Funayama M, Inoue K, Nagashima K, Funae Y, Shimada N, Green C, Kamataki T (1996) ( + )-Cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes. J Pharmacol Exp Ther 277: 768-774
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 768-774
-
-
Nunoya, K.1
Yokoi, T.2
Kimura, K.3
Kodama, T.4
Funayama, M.5
Inoue, K.6
Nagashima, K.7
Funae, Y.8
Shimada, N.9
Green, C.10
Kamataki, T.11
-
15
-
-
7144257874
-
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and ( + )-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)
-
Nunoya K, Yokoi T, Kimura K, Inoue K, Kodama T, Funayama M, Nagashima K, Funae Y, Green C, Kinoshita M, Kamataki T (1998) A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and ( + )-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502). Pharmacogenetics 8: 239-249
-
(1998)
Pharmacogenetics
, vol.8
, pp. 239-249
-
-
Nunoya, K.1
Yokoi, T.2
Kimura, K.3
Inoue, K.4
Kodama, T.5
Funayama, M.6
Nagashima, K.7
Funae, Y.8
Green, C.9
Kinoshita, M.10
Kamataki, T.11
-
16
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura T, Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239: 2370-2378
-
(1964)
J Biol Chem
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
17
-
-
0031737551
-
Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase
-
Oscarson M, Gullsten H, Rautio A, Bernal ML, Sinues B, Dahl M-L, Stengard JH, Pelkonen O, Raunio H, Ingelman-Sundberg M (1998) Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase. FEBS Lett 438: 201-205
-
(1998)
FEBS Lett
, vol.438
, pp. 201-205
-
-
Oscarson, M.1
Gullsten, H.2
Rautio, A.3
Bernal, M.L.4
Sinues, B.5
Dahl, M.-L.6
Stengard, J.H.7
Pelkonen, O.8
Raunio, H.9
Ingelman-Sundberg, M.10
-
18
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270: 414-423
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
19
-
-
0029996291
-
Ethnic-related differences in coumarin 7-hydroxylation activities catalyzed by cytochrome P450 2A6 in liver microsomes of Japanese and Caucasian populations
-
Shimada T, Yamazaki H, Guengerich FP (1996) Ethnic-related differences in coumarin 7-hydroxylation activities catalyzed by cytochrome P450 2A6 in liver microsomes of Japanese and Caucasian populations. Xenobiotica 26: 395-403
-
(1996)
Xenobiotica
, vol.26
, pp. 395-403
-
-
Shimada, T.1
Yamazaki, H.2
Guengerich, F.P.3
-
20
-
-
0008945361
-
Genotyping of CYP2A6 polymorphism in Japanese using a newly developed analysis
-
Abstract
-
Umezu Y, Yokoi T, Nunoya K, Takahashi Y, Kinoshita M, Shimada T, Kamataki T (1998) Genotyping of CYP2A6 polymorphism in Japanese using a newly developed analysis. 118th Annual Meeting Japanese Pharmaceutical Society 28 (Abstract)
-
(1998)
118th Annual Meeting Japanese Pharmaceutical Society
, vol.28
-
-
Umezu, Y.1
Yokoi, T.2
Nunoya, K.3
Takahashi, Y.4
Kinoshita, M.5
Shimada, T.6
Kamataki, T.7
-
21
-
-
0025022689
-
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
-
Yamano S, Tatsuno J, Gonzalez FJ (1990) The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. Biochemistry 29: 1322-1329
-
(1990)
Biochemistry
, vol.29
, pp. 1322-1329
-
-
Yamano, S.1
Tatsuno, J.2
Gonzalez, F.J.3
-
22
-
-
0026744568
-
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
-
Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T (1992) Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis 13: 1789-1794
-
(1992)
Carcinogenesis
, vol.13
, pp. 1789-1794
-
-
Yamazaki, H.1
Inui, Y.2
Yun, C.H.3
Guengerich, F.P.4
Shimada, T.5
-
24
-
-
0031034166
-
Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes
-
Yamazaki H, Inoue K, Turvy CG, Guengerich FP, Shimada T (1997b) Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes. Drug Metab Dispos 25: 168-174
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 168-174
-
-
Yamazaki, H.1
Inoue, K.2
Turvy, C.G.3
Guengerich, F.P.4
Shimada, T.5
-
25
-
-
0032931833
-
Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes
-
Yamazaki H, Inoue K, Hashimoto M, Shimada T (1999a) Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes. Arch Toxicol 73: 65-70
-
(1999)
Arch Toxicol
, vol.73
, pp. 65-70
-
-
Yamazaki, H.1
Inoue, K.2
Hashimoto, M.3
Shimada, T.4
-
26
-
-
0032908959
-
Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes
-
Yamazaki H, Tanaka M, Shimada T (1999b) Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes. J Chromatogr B 721: 13-19
-
(1999)
J Chromatogr B
, vol.721
, pp. 13-19
-
-
Yamazaki, H.1
Tanaka, M.2
Shimada, T.3
-
27
-
-
0025841777
-
Purification and characterization of human liver microsomal cytochrome P-450 2A6
-
Yun CH, Shimada T, Guengerich FP (1991) Purification and characterization of human liver microsomal cytochrome P-450 2A6. Mol Pharmacol 40: 679-685
-
(1991)
Mol Pharmacol
, vol.40
, pp. 679-685
-
-
Yun, C.H.1
Shimada, T.2
Guengerich, F.P.3
|