Recombinant DNA technology as an investigative tool in drug metabolism research

Advanced Drug Delivery Reviews

Volumn 22, Issue 1-2, 1996, Pages 187-213

  Friedberg, Thomas ^a   Wolf, C Roland ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

bacteria; baculovirus; biocatalyst; cDNA directed expression; cell culture; chemical carcinogenesis; cytochrome P450; dru g metabolism; drug research and development; heterologous expression; mammals; mutagenesis; pharmacology; recombinant DNA; toxicology; transgenes; yeast

Indexed keywords

BACTERIA; CELL CULTURE; DNA; DRUG INTERACTIONS; DRUG THERAPY; ENZYMES; GENES; METABOLISM; MUTAGENESIS; PHARMACOKINETICS; PROTEINS; YEAST;

BACULOVIRUS; CHEMICAL CARCINOGENESIS; DNA DIRECTED EXPRESSION; DRUG METABOLISM; HETEROLOGOUS EXPRESSION; PHARMACOLOGY; RECOMBINANT DNA; TOXICOLOGY; TRANSGENES;

GENETIC ENGINEERING;

COMPLEMENTARY DNA; CYTOCHROME P450; DNA; DRUG METABOLIZING ENZYME; NIFEDIPINE; RECOMBINANT DNA; TESTOSTERONE;

BACTERIUM; BACULOVIRUS; CATALYSIS; CHEMICAL CARCINOGENESIS; COST; DRUG INTERACTION; DRUG METABOLISM; DRUG RESEARCH; ENZYME STRUCTURE; GENE EXPRESSION; GENE TARGETING; HUMAN; MAMMAL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; REGULATORY MECHANISM; REVIEW; TRANSGENE; VIRUS; XENOBIOTIC METABOLISM; YEAST;

EID: 0030588661     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(96)00419-X     Document Type: Review

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