-
1
-
-
15844404509
-
Essential role of stat6 in IL-4 signaling
-
Takeda, K., T. Tanaka, W. Shi, M. Matsumoto, M. Minami, S. Kashiwamura, K. Nakanishi, N. Yoshida, T. Kishimoto, and S. Akira. 1996. Essential role of Stat6 in IL-4 signaling. Nature 380:627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
2
-
-
0030587813
-
Impaired IL-13-mediated functions of macrophages in Stat6-deficient mice
-
Takeda, K., M. Kamanaka, T. Tanaka, T. Kishimoto, and S. Akira. 1996. Impaired IL-13-mediated functions of macrophages in Stat6-deficient mice. J. Immunol. 157:3220-3222.
-
(1996)
J. Immunol.
, vol.157
, pp. 3220-3222
-
-
Takeda, K.1
Kamanaka, M.2
Tanaka, T.3
Kishimoto, T.4
Akira, S.5
-
3
-
-
15844374279
-
Lack of IL-4-induced Th2 response and ige class switching in mice with disrupted Stat6 gene
-
Shimoda, K., J. van Deursen, M. Y. Sangster, S. R. Sarawar, R. T. Carson, R. A. Tripp, C. Chu, F. W. Quelle, T. Nosaka, D. A. A. Vignali, P. C. Doherty, G. Grosveld, W. E. Paul, and J. N. Ihle. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
-
4
-
-
0031859134
-
Stat6 is required for IL-4-induced germline ig gene transcription and switch recombination
-
Linchan, L. A., W. D. Warren, P. A. Thompson, M. J. Grusby, and M. T. Berton. 1998. Stat6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J. Immunol. 161:302-310.
-
(1998)
J. Immunol.
, vol.161
, pp. 302-310
-
-
Linchan, L.A.1
Warren, W.D.2
Thompson, P.A.3
Grusby, M.J.4
Berton, M.T.5
-
5
-
-
0028962572
-
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15
-
Lin, J. X., T. S. Migone, M. Tsang, M. Friedmann, J. A. Weatherbee, L. Zhou, A. Yamauchi, E. T. Bloom, J. Meitz, S. John, and W. J. Leonard. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15. Immunity 2:331-339.
-
(1995)
Immunity
, vol.2
, pp. 331-339
-
-
Lin, J.X.1
Migone, T.S.2
Tsang, M.3
Friedmann, M.4
Weatherbee, J.A.5
Zhou, L.6
Yamauchi, A.7
Bloom, E.T.8
Meitz, J.9
John, S.10
Leonard, W.J.11
-
6
-
-
0029035685
-
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor
-
Zurawski, S. M., P. Chomarat, O. Djossou, C. Bidaud, A. N. J. McKenzie, P. Miossec, J. Banchereau, and G. Zurawski. 1995. The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor. J. Biol. Chem. 270:13869-13878.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13869-13878
-
-
Zurawski, S.M.1
Chomarat, P.2
Djossou, O.3
Bidaud, C.4
McKenzie, A.N.J.5
Miossec, P.6
Banchereau, J.7
Zurawski, G.8
-
7
-
-
0030988307
-
Interleukin 4 and interleukin 13: Same response, different receptors
-
Callard, R. E., D. J. Mathews, and L. M. Hibbert. 1997. Interleukin 4 and interleukin 13: same response, different receptors. Biochem. Soc. Trans. 25: 451-455.
-
(1997)
Biochem. Soc. Trans.
, vol.25
, pp. 451-455
-
-
Callard, R.E.1
Mathews, D.J.2
Hibbert, L.M.3
-
8
-
-
0025032511
-
Structure and expression of germline epsilon transcripts in human B cells induced by interleukin-4 to switch to IgE production
-
Gauchat, J.-F., D. A. Lebman, R. L. Coffman, H. Gascan, and J. E. de Vries. 1990. Structure and expression of germline epsilon transcripts in human B cells induced by interleukin-4 to switch to IgE production. J. Exp. Med. 172:463-473.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 463-473
-
-
Gauchat, J.-F.1
Lebman, D.A.2
Coffman, R.L.3
Gascan, H.4
De Vries, J.E.5
-
9
-
-
0027522374
-
Interleukin-13 induces interleukin-4-independent IgG4 and IgE synthesis and CD23 expression by human B cells
-
Punnonen, J., G. Aversa, B. G. Cocks, A. N. J. McKenzie, S. Menon, G. Zurawski, R. de Waal Malefyt, and J. E. de Vries. 1993. Interleukin-13 induces interleukin-4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. USA 90:3730-3734.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3730-3734
-
-
Punnonen, J.1
Aversa, G.2
Cocks, B.G.3
McKenzie, A.N.J.4
Menon, S.5
Zurawski, G.6
De Waal Malefyt, R.7
De Vries, J.E.8
-
10
-
-
0028201726
-
Acquisition of lymphokine-producing phenotype by CD4+ T cells
-
Seder, R. A., and W. E. Paul. 1994. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu. Rev. Immunol. 12:635-673.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 635-673
-
-
Seder, R.A.1
Paul, W.E.2
-
11
-
-
0026616876
-
Induction of Th1 and Th2 responses: A key role for the "natural" immune response?
-
Romagnani, S. 1992. Induction of Th1 and Th2 responses: a key role for the "natural" immune response? Immunol. Today 13:379-381.
-
(1992)
Immunol. Today
, vol.13
, pp. 379-381
-
-
Romagnani, S.1
-
12
-
-
0028288179
-
Lymphokine production by human T cells in disease states
-
Romagnani, S. 1994. Lymphokine production by human T cells in disease states. Annu. Rev. Immunol. 12:227-257.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 227-257
-
-
Romagnani, S.1
-
13
-
-
0025222698
-
Il-4 directs the development of th2-like helper effectors. J
-
Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796-3806.
-
(1990)
Immunol.
, vol.145
, pp. 3796-3806
-
-
Swain, S.L.1
A D Weinberg, M.E.2
Huston, G.3
-
14
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grünig, G., M. Warnock, A. E. Wakil, R. Venkayya, F. Brombacher, D. M. Rennick, D. Sheppard, M. Mohrs, D. D. Donaldson, R. M. Locksley, and D. B. Corry. 1998. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 282:2261-2263.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grünig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
Sheppard, D.7
Mohrs, M.8
Donaldson, D.D.9
Locksley, R.M.10
Corry, D.B.11
-
15
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp, M., J. Luyimbazi, X. Xu, B. Schofield, T. Y. Neben, C. L. Karp, and D. D. Donaldson. 1998. Interleukin-13: central mediator of allergic asthma. Science 282:2258-2261.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
16
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf, M., G. Le Gros, M. Bachmann, M. C. Lamers, IL Bluethmann, and G. Köhler. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362:245-248.
-
(1993)
Nature
, vol.362
, pp. 245-248
-
-
Kopf, M.1
Gros, G.L.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, I.L.5
Köhler, G.6
-
17
-
-
0032167664
-
Impaired development of Th2 cells in IL-13-deficient mice
-
McKenzie, G., C. L. Emson, S. E. Bell, S. Anderson, P. Fallon, G. Zurawski, R. Murray, R. Grencis, and A. N. J. McKenzie. 1998. Impaired development of Th2 cells in IL-13-deficient mice. Immunity 9:423-432.
-
(1998)
Immunity
, vol.9
, pp. 423-432
-
-
McKenzie, G.1
Emson, C.L.2
Bell, S.E.3
Anderson, S.4
Fallon, P.5
Zurawski, G.6
Murray, R.7
Grencis, R.8
McKenzie, A.N.J.9
-
18
-
-
0026328818
-
Generation and analysis of interleukin-4 deficient mice
-
Kühn, R., K. Rajewsky, and W. Muller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254:707-710.
-
(1991)
Science
, vol.254
, pp. 707-710
-
-
Kühn, R.1
Rajewsky, K.2
Muller, W.3
-
19
-
-
0032545279
-
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction
-
Haque, S. J., P. Harbor, M. Tabrizi, T. Yi, and B. R. G. Williams. 1998. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction. J. Biol. Chem. 273:33893-33896.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33893-33896
-
-
Haque, S.J.1
Harbor, P.2
Tabrizi, M.3
Yi, T.4
Williams, B.R.G.5
-
20
-
-
0027787877
-
Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor
-
Russell, S. M., A. D. Keegan, N. Harada, Y. Nakamura, M. Noguchi, P. Leland, M. C. Friedmann, A. Miyajima, R. K. Puri, W. E. Paul, and W. J. Leonard. 1993. Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science 262:1880-1883.
-
(1993)
Science
, vol.262
, pp. 1880-1883
-
-
Russell, S.M.1
Keegan, A.D.2
Harada, N.3
Nakamura, Y.4
Noguchi, M.5
Leland, P.6
Friedmann, M.C.7
Miyajima, A.8
Puri, R.K.9
Paul, W.E.10
Leonard, W.J.11
-
21
-
-
0030765924
-
Jaks, Stats, cytokine signal transduction, and immunoregulation: Are we there yet?
-
O'Shea, J. J. 1997. Jaks, Stats, cytokine signal transduction, and immunoregulation: are we there yet? Immunity 7:1-7.
-
(1997)
Immunity
, vol.7
, pp. 1-7
-
-
O'Shea, J.J.1
-
22
-
-
0030949167
-
Stat6: Its role in interleukin 4-mediated biological functions
-
Takeda, K., T. Kishimoto, and S. Akira. 1997. Stat6: its role in interleukin 4-mediated biological functions. J. Mol. Med. 75:317-326.
-
(1997)
J. Mol. Med.
, vol.75
, pp. 317-326
-
-
Takeda, K.1
Kishimoto, T.2
Akira, S.3
-
23
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
-
Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
24
-
-
0030788973
-
Identification of a Stat-6-responsive element in the promoter of the human interleukin-4 gene
-
Curiel, R. E., R. Lahesmaa, J. Subleski, M. Cippitelli, R. A. Kirken, H. A. Young, and P. Ghosh. 1997. Identification of a Stat-6-responsive element in the promoter of the human interleukin-4 gene. Eur. J. Immunol. 27: 1982-1987.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1982-1987
-
-
Curiel, R.E.1
Lahesmaa, R.2
Subleski, J.3
Cippitelli, M.4
Kirken, R.A.5
Young, H.A.6
Ghosh, P.7
-
25
-
-
0032055195
-
2-microglobulin independent and develop normally in the absence of IL-4 priming of T cells
-
2-microglobulin independent and develop normally in the absence of IL-4 priming of T cells. J. Immunol. 160:3299-3304.
-
(1998)
J. Immunol.
, vol.160
, pp. 3299-3304
-
-
Morris, S.C.1
Coffman, R.L.2
Finkelman, F.D.3
-
26
-
-
0032536837
-
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyper-responsiveness and mucus production
-
Kuperman, D., B. Schofield, M. Wills-Karp, and M. J. Grusby. 1998. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyper-responsiveness and mucus production. J. Exp. Med. 187:939-948.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 939-948
-
-
Kuperman, D.1
Schofield, B.2
Wills-Karp, M.3
Grusby, M.J.4
-
27
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik, P. C., and M. L. Stephenson. 1978. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA 75:280-284.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
28
-
-
0005772676
-
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
-
Stephonson, M. L., and P. C. Zamecnik. 1978. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc. Natl. Acad. Sci. USA 75:285-288.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 285-288
-
-
Stephonson, M.L.1
Zamecnik, P.C.2
-
29
-
-
0031234479
-
Antisense oligonucleotides as therapeutic agents
-
Alama, A., F. Barbieri, M. Cagnoli, and G. Schettini. 1997. Antisense oligonucleotides as therapeutic agents. Pharmacol. Res. 36:171-178.
-
(1997)
Pharmacol. Res.
, vol.36
, pp. 171-178
-
-
Alama, A.1
Barbieri, F.2
Cagnoli, M.3
Schettini, G.4
-
30
-
-
0029792095
-
Antisense oligonucleotides as inhibitors of signal transduction: Development from research tools to therapeutic agents
-
Dean, N. M., R. McKay, L. Miraglia, T. Geiger, M. Müller, D. Fabbro, and C. F. Bennett. 1996. Antisense oligonucleotides as inhibitors of signal transduction: development from research tools to therapeutic agents. Biochem. Soc. Trans. 24:623-629.
-
(1996)
Biochem. Soc. Trans.
, vol.24
, pp. 623-629
-
-
Dean, N.M.1
McKay, R.2
Miraglia, L.3
Geiger, T.4
Müller, M.5
Fabbro, D.6
Bennett, C.F.7
-
31
-
-
0030980684
-
An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice
-
Bennett, C. F., D. Kornbrust, S. Henry, K. Stecker, R. Howard, S. Cooper, S. Dutson, W. Hall, and H. I. Jacoby. 1997. An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice. J. Pharmacol. Exp. Ther. 280:988-1000.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 988-1000
-
-
Bennett, C.F.1
Kornbrust, D.2
Henry, S.3
Stecker, K.4
Howard, R.5
Cooper, S.6
Dutson, S.7
Hall, W.8
Jacoby, H.I.9
-
32
-
-
0030071007
-
Effect of different chemically modified oligodeoxynucleotides on immune stimulation
-
Zhao, Q., J. Temsamani, P. L. Iadarola, Z. Jiang, and S. Agrawal. 1996. Effect of different chemically modified oligodeoxynucleotides on immune stimulation. Biochem. Pharmacol. 51:173-182.
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 173-182
-
-
Zhao, Q.1
Temsamani, J.2
Iadarola, P.L.3
Jiang, Z.4
Agrawal, S.5
-
33
-
-
0029811432
-
Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs
-
Krieg, A. M., S. Matson, and E. Fisher. 1996. Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs. Antisense Nucleic Acid Drug Dev. 6:133-139.
-
(1996)
Antisense Nucleic Acid Drug Dev.
, vol.6
, pp. 133-139
-
-
Krieg, A.M.1
Matson, S.2
Fisher, E.3
-
34
-
-
0000217983
-
Immune stimulation by oligonucleotides
-
S. T. Crooke, editor. Springer, Heidelberg.
-
Krieg, A. M. 1998. Immune stimulation by oligonucleotides. In Antisense Research and Application. S. T. Crooke, editor. Springer, Heidelberg. 243-262.
-
(1998)
Antisense Research and Application
, pp. 243-262
-
-
Krieg, A.M.1
-
35
-
-
0029943679
-
Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity
-
Stein, C. A. 1996. Phosphorothioate antisense oligodeoxynucleotides: questions of specificity. Trends Biotechnol. 14:147-149.
-
(1996)
Trends Biotechnol.
, vol.14
, pp. 147-149
-
-
Stein, C.A.1
-
36
-
-
0002723926
-
Basic principles of antisense therapeutics
-
S. T. Crooke, editor. Springer, Heidelberg
-
Crooke, S. T. 1998. Basic principles of antisense therapeutics. In Antisense Research and Application. S. T. Crooke, editor. Springer, Heidelberg. 1-50.
-
(1998)
Antisense Research and Application
, pp. 1-50
-
-
Crooke, S.T.1
-
37
-
-
18844455464
-
Second generation of antisense oligonucleotides: From nuclease resistance to biological efficacy in animals
-
Altmann, K.-H., N. M. Dean, D. Fabbro, S. M. Freier, T. Geiger, R. Haener, D. Huesken, P. Martin, B. P. Monia, M. Muller, F. Natt, P. Nicklin, J. Phillips, U. Pieles, H. Sasmor, and H. E. Moser. 1996. Second generation of antisense oligonucleotides: from nuclease resistance to biological efficacy in animals. Chimia 50:168-176.
-
(1996)
Chimia
, vol.50
, pp. 168-176
-
-
Altmann, K.-H.1
Dean, N.M.2
Fabbro, D.3
Freier, S.M.4
Geiger, T.5
Haener, R.6
Huesken, D.7
Martin, P.8
Monia, B.P.9
Muller, M.10
Natt, F.11
Nicklin, P.12
Phillips, J.13
Pieles, U.14
Sasmor, H.15
Moser, H.E.16
-
38
-
-
0026659648
-
The effect of cytokines and mitogens on the induction of Cε germline transcripts in a human Burkitt lymphoma cell line
-
Ichiki, T., W. Takahashi, and T. Watanabe. 1992. The effect of cytokines and mitogens on the induction of Cε germline transcripts in a human Burkitt lymphoma cell line. Int. Immunol. 4:747-754.
-
(1992)
Int. Immunol.
, vol.4
, pp. 747-754
-
-
Ichiki, T.1
Takahashi, W.2
Watanabe, T.3
-
39
-
-
0025775925
-
Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells
-
Shapira, S. K., H. H. Jabara, C. P. Thienes, D. J. Ahern, D. Vercelli, H. J. Gould, and R. S. Geha. 1991. Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells. Proc. Natl. Acad. Sci. USA 88:7528-7532.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7528-7532
-
-
Shapira, S.K.1
Jabara, H.H.2
Thienes, C.P.3
Ahern, D.J.4
Vercelli, D.5
Gould, H.J.6
Geha, R.S.7
-
40
-
-
0026532658
-
Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen
-
Shapira, S. K., D. Vercelli, H. H. Jabara, S. M. Fu, and R. S. Geha. 1992. Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen. J. Exp. Med. 175:289-292.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 289-292
-
-
Shapira, S.K.1
Vercelli, D.2
Jabara, H.H.3
Fu, S.M.4
Geha, R.S.5
-
41
-
-
0027960913
-
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation
-
Castigli, E., F. W. Alt, L. Davidson, A. Bottaro, E. Mizoguchi, A.K. Bhan, and R. S. Geha. 1994. CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Immunology 91: 12135-12139.
-
(1994)
Immunology
, vol.91
, pp. 12135-12139
-
-
Castigli, E.1
Alt, F.W.2
Davidson, L.3
Bottaro, A.4
Mizoguchi, E.5
Bhan, A.K.6
Geha, R.S.7
-
42
-
-
0026568296
-
Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumour necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production
-
Gauchat, J. F., G. Aversa., H. Gascan, and J. E. de-Vries. 1992. Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumour necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production. Int. Immunol. 4: 397-406.
-
(1992)
Int. Immunol.
, vol.4
, pp. 397-406
-
-
Gauchat, J.F.1
Aversa, G.2
Gascan, H.3
De-Vries, J.E.4
-
43
-
-
0032541985
-
Mixed-backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects
-
Zhou, W., and S. Agrawal. 1998. Mixed-backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects. Bioorg. Med. Chem. Lett. 8:3269-3274.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 3269-3274
-
-
Zhou, W.1
Agrawal, S.2
-
44
-
-
0031299310
-
First-and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinase
-
Monia, B. P. 1997. First-and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinase. Ciba Found. Symp. 209: 107-123.
-
(1997)
Ciba Found. Symp.
, vol.209
, pp. 107-123
-
-
Monia, B.P.1
-
45
-
-
0033555551
-
Characterisation of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
-
McKay, R. A., L. J. Miraglia, L. L. Cummins, S. R. Owens, H. Sasmor, and N. M. Dean. 1999. Characterisation of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J. Biol. Chem. 274:1715-1722.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1715-1722
-
-
McKay, R.A.1
Miraglia, L.J.2
Cummins, L.L.3
Owens, S.R.4
Sasmor, H.5
Dean, N.M.6
-
46
-
-
0031010177
-
2′-O-(2-melhoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells
-
Baker, B. F., S. S. Lot, T. P. Condon, S. Cheng-Flournoy, E. A. Lesnik, H. M. Sasmor, and C. F. Bennett. 1997. 2′-O-(2-melhoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells. J. Biol Chem. 272:11994-12000.
-
(1997)
J. Biol Chem.
, vol.272
, pp. 11994-12000
-
-
Baker, B.F.1
Lot, S.S.2
Condon, T.P.3
Cheng-Flournoy, S.4
Lesnik, E.A.5
Sasmor, H.M.6
Bennett, C.F.7
-
47
-
-
12644268252
-
Sequence-specific antitumour activity of phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
-
Monia, B. P., H. Sasmor, J. F. Johnston, S. M. Freier, E. A. Lesnik, M. Muller, T. Geiger, K. Altmann, H. Moser, and D. Fabbro. 1996. Sequence-specific antitumour activity of phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc. Natl. Acad. Sci. USA 93:15481-15484.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15481-15484
-
-
Monia, B.P.1
Sasmor, H.2
Johnston, J.F.3
Freier, S.M.4
Lesnik, E.A.5
Muller, M.6
Geiger, T.7
Altmann, K.8
Moser, H.9
Fabbro, D.10
-
48
-
-
0031204428
-
Identification of a Stat6 domain required for IL-4-induced activation of transcription
-
Lu, B., M. Reichel, D. A. Fisher, J. F. Smith, and P. Rothman. 1997. Identification of a Stat6 domain required for IL-4-induced activation of transcription. J. Immunol. 159:1255-1264.
-
(1997)
J. Immunol.
, vol.159
, pp. 1255-1264
-
-
Lu, B.1
Reichel, M.2
Fisher, D.A.3
Smith, J.F.4
Rothman, P.5
-
49
-
-
0027173826
-
Regulation of the expression of human Cε germline transcript. Identification of a novel IL-4 responsive element
-
Ichiki, T., W. Takahashi, and T. Watanabe. 1993. Regulation of the expression of human Cε germline transcript. Identification of a novel IL-4 responsive element J. Immunol. 150:5408-5417.
-
(1993)
J. Immunol.
, vol.150
, pp. 5408-5417
-
-
Ichiki, T.1
Takahashi, W.2
Watanabe, T.3
-
50
-
-
0004951883
-
Pharmacological activity of antisense oligonucleotides in animal models of disease
-
S. T. Crooke, editor. Springer, Hiedelberg
-
Monia, B. P., and N. M. Dean. 1998. Pharmacological activity of antisense oligonucleotides in animal models of disease. In Antisense Research and Application. S. T. Crooke, editor. Springer, Hiedelberg. 427-143.
-
(1998)
Antisense Research and Application
, pp. 427-1143
-
-
Monia, B.P.1
Dean, N.M.2
-
51
-
-
0000438002
-
Clinical antiviral activities
-
S. T. Crooke, editor. Springer, Hiedelberg
-
Hutcherson, S. L. 1998. Clinical antiviral activities. In Antisense Research and Application. S. T. Crooke, editor. Springer, Hiedelberg. 445-462.
-
(1998)
Antisense Research and Application
, pp. 445-462
-
-
Hutcherson, S.L.1
-
52
-
-
0032500293
-
First "antisense" drug will treat CMV retinitis
-
Marwick, C. 1998. First "antisense" drug will treat CMV retinitis. JAMA 280:871.
-
(1998)
JAMA
, vol.280
, pp. 871
-
-
Marwick, C.1
-
53
-
-
0030819086
-
Antisense oligonucleotides: A new therapeutic approach
-
Temsamani, J., and P. Guinot. 1997. Antisense oligonucleotides: a new therapeutic approach. Biotechnol. Appl. Biochem. 26:65-71.
-
(1997)
Biotechnol. Appl. Biochem.
, vol.26
, pp. 65-71
-
-
Temsamani, J.1
Guinot, P.2
-
54
-
-
0030271959
-
Antisense oligonucleotides: Towards clinical trials
-
Agrawal, S. 1996. Antisense oligonucleotides: towards clinical trials. Trends Biotechnol. 14:376-387.
-
(1996)
Trends Biotechnol.
, vol.14
, pp. 376-387
-
-
Agrawal, S.1
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