Type I β-turn conformation is important for biological activity of the melanocyte-stimulating hormone analogues

European Journal of Biochemistry

Volumn 265, Issue 1, 1999, Pages 430-440

  Li, Song Zhe ^a   Lee, Jung Hoon ^b   Lee, Weontae ^b   Yoon, Chang Ju ^c   Baik, Ja Hyun ^a   Lim, Sung Kil ^a,d  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

Author keywords

Melanocortin; Melanocyte stimulating hormone receptor; NMR; Receptor binding and cAMP generating activity; Type I turn

Indexed keywords

INTERMEDIN DERIVATIVE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; HORMONE ACTION; HORMONE STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; RAT; STRUCTURE ANALYSIS;

ALPHA-MSH; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RATS; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, CORTICOTROPIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0033215018     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00763.x     Document Type: Article

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