DNA mismatch binding in human lung tumor cell lines

Lung Cancer

Volumn 26, Issue 1, 1999, Pages 15-25

  Zienolddiny, Shanbeh ^a   Ryberg, David ^a   Gazdar, Adi F ^b   Haugen, Aage ^a  

^a NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Alkylation resistance; Bandshift; Immunoblotting; Lung cancer; Microsatellite instability; Mismatch repair

Indexed keywords

CELL DNA; MICROSATELLITE DNA;

ARTICLE; BASE MISPAIRING; CANCER CELL CULTURE; CONTROLLED STUDY; DNA BINDING; DNA DETERMINATION; DNA REPAIR; GENE FUNCTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPHOBLASTOID CELL LINE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL;

ALKYLATION; BASE PAIR MISMATCH; CELL EXTRACTS; CELL-FREE SYSTEM; DNA REPAIR; HUMANS; IMMUNOBLOTTING; LUNG NEOPLASMS; MICROSATELLITE REPEATS; TUMOR CELLS, CULTURED;

EID: 0033214377     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(99)00069-0     Document Type: Article

References (47)

1. Loeb L.A. Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res. 54:1994;5059-5063.
2. Eshleman J.R., Markowitz S.D. Mismatch repair defects in human carcinogenesis. Hum. Mol. Genet. 5 Spec No. 1489-94:1996;1489-1494.
3. Kinzler K.W., Vogelstein B. Lessons from hereditary colorectal cancer. Cell. 87:1996;159-1570.
4. Kunkel T.A. DNA-mismatch repair. The intricacies of eukaryotic spell-checking. Curr. Biol. 5:1995;1091-1094.
5. Esteller M., Levine R., Baylin S.B., Ellenson L.H., Herman J.G. MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. Oncogene. 17:1998;2413-2417.
6. Herman J.G., Umar A., Polyak K., Graff J.R., Ahuja N., Issa J.P., Markowitz S., Willson J.K., Hamilton S.R., Kinzler K.W., Kane M.F., Kolodner R.D., Vogelstein B., Kunkel T.A., Baylin S.B. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl. Acad. Sci. USA. 95:1998;6870-6875.
7. Kane M.F., Loda M., Gaida G.M., Lipman J., Mishra R., Goldman H., Jessup J.M., Kolodner R. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 57:1997;808-811.
8. Edelmann W., Yang K., Umar A., Heyer J., Lau K., Fan K., Liedtke W., Cohen P.E., Kane M.F., Lipford J.R., Yu N., Crouse G.F., Pollard J.W., Kunkel T., Lipkin M., Kolodner R., Kucherlapati R. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell. 91:1997;467-477.
9. Nicolaides N.C., Papadopoulos N., Liu B., Wei Y.F., Carter K.C., Ruben S.M., Rosen C.A., Haseltine W.A., Fleischmann R.D., Fraser C.M. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 371:1994;75-80.
10. Papadopoulos N., Nicolaides N.C., Liu B., Parsons R., Lengauer C., Palombo F., D'Arrigo A., Markowitz S., Willson J.K., Kinzler K.W. Mutations of GTBP in genetically unstable cells [see comments]. Science. 268:1995;1915-1917.
11. Risinger J.I., Umar A., Barrett J.C., Kunkel T.A. A hPMS2 mutant cell line is defective in strand-specific mismatch repair. J. Biol. Chem. 270:1995;18183-18186.
12. Risinger J.I., Umar A., Boyd J., Berchuck A., Kunkel T.A., Barrett J.C. Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. Nat. Genet. 14:1996;102-105.
13. Prolla T.A., Baker S.M., Harris A.C., Tsao J.L., Yao X., Bronner C.E., Zheng B., Gordon M., Reneker J., Arnheim N., Shibata D., Bradley A., Liskay R.M. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat. Genet. 18:1998;276-279.
14. Lindstedt B.A., Ryberg D., Haugen A. Rare alleles at different VNTR loci among lung-cancer patients with microsatellite instability in tumours. Int. J. Cancer. 70:1997;412-415.
15. Merlo A., Mabry M., Gabrielson E., Vollmer R., Baylin S.B., Sidransky D. Frequent microsatellite instability in primary small cell lung cancer. Cancer Res. 54:1994;2098-2101.
16. Pifarre A., Rosell R., Monzo M., de Anta J.M., Moreno I., Sanchez J.J., Ariza A., Mate J.L., Martinez E., Sanchez M. Prognostic value of replication errors on chromosomes 2p and 3p in non- small-cell lung cancer. Br. J. Cancer. 75:1997;184-189.
17. Shridhar V., Siegfried J., Hunt J., del Mar A., Smith D.I. Genetic instability of microsatellite sequences in many non-small cell lung carcinomas. Cancer Res. 54:1994;2084-2087.
18. Benachenhou N., Guiral S., Gorska-Flipot I., Labuda D., Sinnett D. High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer. Int. J. Cancer. 77:1998;173-180.
19. Inokuchi K., Ikejima M., Watanabe A., Nakajima E., Orimo H., Nomura T., Shimada T. Loss of expression of the human MSH3 gene in hematological malignancies. Biochem. Biophys. Res. Commun. 214:1995;171-179.
20. Davis T.W., Wilson-Van P.C., Meyers M., Kunugi K.A., Cuthill S., Reznikoff C., Garces C., Boland C.R., Kinsella T.J., Fishel R., Boothman D.A. Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation. Cancer Res. 58:1998;767-778.
21. Meyers M., Theodosiou M., Acharya S., Odegaard E., Wilson T., Lewis J.E., Davis T.W., Wilson-Van P.C., Fishel R., Boothman D.A. Cell cycle regulation of the human DNA mismatch repair genes hMSH2, hMLH1, and hPMS2. Cancer. Res. 57:1997;206-208.
22. Oie H.K., Russell E.K., Carney D.N., Gazdar A.F. Cell culture methods for the establishment of the NCI series of lung cancer cell lines. J. Cell. Biochem. 24 Suppl. 24-31:1996;24-31.
23. Kick G., Messer G., Goetz A., Plewig G., Kind P. Photodynamic therapy induces expression of interleukin 6 by activation of AP-1 but not NF-kappa B DNA binding. Cancer Res. 55:1995;2373-2379.
24. Lowry O., Rosebrough N., Farr A., Randall R. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
25. Jiricny J., Hughes M., Corman N., Rudkin B.B. A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches. Proc. Natl. Acad. Sci. USA. 85:1988;8860-8864.
26. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 248-54. 72:1976;248-254.
27. Mollerup S., Rivedal E., Moehle L., Haugen A. Nickel(II) induces alterations in EGF- and TGF-beta 1-mediated growth control during malignant transformation of human kidney epithelial cells. Carcinogenesis. 17:1996;361-367.
28. 6-methylguanine. Carcinogenesis. 12:1991;2305-2309.
29. 6- benzylguanine using a transgenic model. Cancer Res. 56:1996;1880-1885.
30. Karran P., Stephenson C. Mismatch binding proteins and tolerance to alkylating agents in human cells. Mutat. Res. 236:1990;269-275.
31. Acharya S., Wilson T., Gradia S., Kane M.F., Guerrette S., Marsischky G.T., Kolodner R., Fishel R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc. Natl. Acad. Sci. USA. 93:1996;13629-13634.
32. O'Regan N.E., Branch P., Macpherson P., Karran P. hMSH2-independent DNA mismatch recognition by human proteins. J. Biol. Chem. 271:1996;1789-1796.
33. Fishel R., Ewel A., Lee S., Lescoe M.K., Griffith J. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein. Science. 266:1994;1403-1405.
34. Gradia S., Acharya S., Fishel R. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell. 91:1997;995-1005.
35. Whitehouse A., Deeble J., Taylor G.R., Guillou P.J., Phillips S.E., Meredith D.M., Markham A.F. Mapping the minimal domain of hMSH-2 sufficient for binding mismatched oligonucleotides. Biochem. Biophys. Res. Commun. 232:1997;10-13.
36. Johnson R.E., Kovvali G.K., Guzder S.N., Amin N.S., Holm C., Habraken Y., Sung P., Prakash L., Prakash S. Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair. J. Biol. Chem. 271:1996;27987-27990.
37. Umar A., Buermeyer A.B., Simon J.A., Thomas D.C., Clark A.B., Liskay R.M., Kunkel T.A. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell. 87:1996;65-73.
38. Wood R.D., Shivji M.K. Which DNA polymerases are used for DNA-repair in eukaryotes? Carcinogenesis. 18:1997;605-610.
39. Perucho M. Cancer of the microsatellite mutator phenotype. Biol. Chem. 377:1996;675-684.
40. Lengauer C., Kinzler K.W., Vogelstein B. Genetic instabilities in human cancers. Nature. 396:1998;643-649.
41. Zhou X.P., Hoang J.M., Cottu P., Thomas G., Hamelin R. Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors. Oncogene. 15:1997;1713-1718.
42. Branch P., Aquilina G., Bignami M., Karran P. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature. 362:1993;652-654.
43. Branch P., Hampson R., Karran P. DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res. 55:1995;2304-2309.
44. Dosch J., Christmann M., Kaina B. Mismatch G-T binding activity and MSH2 expression is quantitatively related to sensitivity of cells to methylating agents. Carcinogenesis. 19:1998;567-573.
45. Richards B., Zhang H., Phear G., Meuth M. Conditional mutator phenotypes in hMSH2-deficient tumor cell lines [see comments]. Science. 277:1997;1523-1526.
46. Wei Q., Cheng L., Hong W.K., Spitz M.R. Reduced DNA repair capacity in lung cancer patients. Cancer Res. 56:1996;4103-4107.
47. Wei Q., Spitz M.R. The role of DNA repair capacity in susceptibility to lung cancer: a review. Cancer. Metastasis. Rev. 16:1997;295-307.