Cell cycle regulation of the human DNA mismatch repair genes hMSH2, hMLH1, and hPMS2

Cancer Research

Volumn 57, Issue 2, 1997, Pages 206-208

  Meyers, Mark ^a   Theodosiou, Maria ^a   Acharya, Samir ^b   Odegaard, Eric ^a   Wilson, Teresa ^a   Lewis, Janet E ^a   Davis, T W ^a   Wilson Van Patten, Carmell ^a   Fishel, Richard ^b   Boothman, David A ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; MESSENGER RNA;

ARTICLE; BASE MISPAIRING; CELL CYCLE; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPAIR; FAMILIAL CANCER; GENE CONTROL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; GENES, CDC; HUMANS; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER;

EID: 15444355644     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Lynch, H. T., Smyrk, T., and Lynch, J. F. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome). Int. J. Cancer, 69: 38-43, 1996.
2. Fishel, R., Lescoe, M. K., Rao, M. R. S., Copeland, N. G., Jenkins, N. A., Garber, J., Kane, M., and Kolodner, R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75: 1027-1038, 1993.
3. Leach, F. S., Nicolaidcs, N. C., Papadopoulos, N., Liu, B., Jen, J., Parsons, R., Peltomaki, P., Sistonen, P., Aaltonen, L. A., Nystrom-Lahti, M., Guan, X-Y., Zhang, J., Meltaer, P. S., Yu, J-W., Kao, F-T., Chen, D. J., Cerosaletti, K. M., Fournier, R. E. K., Todd, S., Lewis, T., Leach, R. J., Naylor, S. L., Weissenbach, J., Mecklin, J-P., Jarvinen, H., Petersen, G. M., Hamilton, S. R., Green, J., Jass, J., Watson, P., Lynch, H. T., Trent, J. M., de la Chapelle, A., Kinzler, K. W., and Vogelstein, B. Mutations of a mutS homolog in hereditary nonpolyposis colorcctal cancer. Cell, 75: 1215-1225, 1993.
4. Bronner, C. E., Baker, S. M., Morrison, P. T., Warren, G., Smith, L. G., Lescoe, M. K., Kane, M., Earabino, C., Lipford, J., Lindblom, A., Tannergard, P., Bollag, R. J., Godwin, A. R., Ward, D. C., Nordenskjold, M., Fishel, R., Kolodner, R., and Liskay, R. M. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature (Lond.), 368: 258-261, 1994.
5. Papadopoulos, N., Nicolaides, N. C., Wei, Y. F., Ruben, S. M., Carter, K. C., Rosen, C. A., Haseltine, W. A., Fleischmann, R. D., Fraser, C. M., Adams, M. D., Venter, J. C., Hamilton, S. R., Petersen, G. M., Watson, P., Lynch, H. T., Peltomaki, P., Mecklin, J-P., de la Chapelle, A., Kinzler, K. W., and Vogelstein, B. Mutation of a mutL homolog in hereditary colon cancer. Science (Washington DC), 263: 1625-1629, 1994.
6. Nicolaides, N. C., Papadopoulos, N., Liu, B., Wei, Y-F., Carter, K. C., Ruben, S. M., Rosen, C. A., Haseltine, W. A., Fleischmann, R. D., Fraser, C. M., Adams, M. D., Venter, J. C., Dunlop, M. G., Hamilton, S. R., Petersen, G. M., de la Chapelle, A., Vogelstein, B., and Kinzler, K. W. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature (Lond.), 371: 75-80, 1994.
7. Modrich, P., and Lahue, R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem., 65: 101-133, 1996.
8. Fishel, R., Ewel, A., and Lescoe, M. K. Purified human MSH2 protein binds to DNA containing mismatched nucleotides. Cancer Res., 54: 5539-5542, 1994.
9. Liu, B., Parsons, R., Papadopoulos, N., Nicolaides, N. C., Lynch, H. T., Watson, P., Jass, J. R., Dunlop, M., Wyllie, A., Peltomaki, P., de la Chapelle, A., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat. Med., 2: 169-174, 1996.
10. Kolodner, R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev., 10: 1433-1442, 1996.
11. Acharya, S., Wilson, T., Gradia, S., Kane, M. F., Guerrette, S., Marsischky, G. T., Kolodner, R., and Fishel, R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc. Natl. Acad. Sci. USA, 93: 13629-13634, 1996.
12. Prolla, T. A., Pang. Q., Alani, E., Kolodner, R. D., and Liskay, R. M. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science (Washington DC), 265: 1091-1093, 1994.
13. Koi, M., Umar, A., Chauhan, D. P., Cherian, S. P., Carethers, J. M., Kunkel, T. A., and Boland, C. R. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous HMLH1 mutation. Cancer Res., 54: 4308-4312, 1994.
14. 2 cell cycle checkpoint. Cancer Res., 55: 3721-3725, 1995.
15. Carethers, J. M., Hawn, M. T., Chauhan, D. P., Luce, M. C., Marra, G., Koi, M., and Boland, C. R. Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N′-nitro-N-nitrosoguanidine. J. Clin. Invest., 95: 199-206, 1996.
16. Umar, A., Buermeyer, A. B., Simon, J. A., Thomas, D. C., Clark, A. B., Liskay, R. M., and Kunkel, T. A. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell, 87: 65-73, 1996.
17. 1. Genes Dev., 7: 812-821, 1993.
18. 1/S boundary may occur in human IMR-90 diploid fibroblasts during senescence. J. Cell. Physiol., 160: 531-538, 1994.
19. Taylor, I. W. A rapid single step staining technique for DNA analysis by flow microfluorimetry. J. Histochem. Cytochem., 28: 1021-1024, 1980.
20. Laborda, J. 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO. Nucleic Acids Res., 19: 3998, 1991.
21. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2, pp. 18.62-18.63. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
22. Keyomarsi, K., and Pardee, A. B. Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc. Natl. Acad. Sci. USA, 90: 1112-1116, 1993.
23. Ashihara, T., and Baserga, R. Cell synchronization. In: W. J. Jakoby and I. H. Pastan (eds.), Methods in Enzymology, Vol. LVIII, pp. 248-262. San Diego: Academic Press, Inc., 1979.
24. Yan, Z.-A., Li, X. Z., and Zhou, X. T. The effect of hydroxyurea on the expression of the common fragile site at 3p14. J. Med. Genet., 24: 593-596, 1987.
25. Yang, S.-J., Hahn, G. M., and Bagshaw, M. A. Chromosome aberrations induced by thymidine. Exp. Cell Res., 42: 130-135, 1966.
26. Moore, R. C., and Randall, C. Different effects of 1-β-D-arabinofuranosylcytos and aphidicolin in S-phase cells-chromosome aberrations, cell-cycle delay and cytotoxicity. Mutation Res., 178: 73-80, 1987.
27. Boothman, D. A., Meyers, M., Fukunaga, N., and Lee, S. W. Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells. Proc. Natl. Acad. Sci. USA, 90: 7200-7204, 1993.
28. Goswami, P. C., Roti Roti, J. L., and Hunt, C. R. The cell cycle-coupled expression of topoisomerase II α during S phase is regulated by mRNA stability and is disrupted by heat shock or ionizing radiation. Mol. Cell. Biol., 16: 1500-1508, 1996.
29. Fishel, R., and Kolodner, R. D. Identification of mismatch repair genes and their role in the development of cancer. Curr. Opin. Genet. Dev., 5: 382-395, 1995.