Apoptosis induction by a novel anti-prostate cancer compound, BMD188 (A fatty acid-containing hydroxamic acid), requires the mitochondrial respiratory chain

Cancer Research

Volumn 59, Issue 17, 1999, Pages 4343-4355

  Joshi, Bindu ^b   Li, Li ^b   Taffe, Bonita G ^b   Zhu, Zhenyu ^b   Wahl, Sharon ^e   Tian, Hongsheng ^e   Ben Josef, Edgar ^b,c,d   Taylor, John D ^b,c,d   Porter, Arthur T ^b,c,d   Tang, Dean G ^a,b,c,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b WAYNE STATE UNIVERSITY   (United States)

^c KARMANOS CANCER INSTITUTE   (United States)

^d HARPER UNIVERSITY HOSPITAL   (United States)

^e NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXY 4 (1 NAPHTHYL) 6 OCTYLPIPERIDINE 2 ONE; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOCHROME C OXIDASE; HYDROXAMIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; ELECTRON TRANSPORT; HUMANS; HYDROXAMIC ACIDS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; PIPERIDONES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; STAUROSPORINE; TUMOR CELLS, CULTURED;

EID: 0033198390     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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