Expression of L-selectin on Th1 cells is regulated by IL-12

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1214-1221

  Van Wely, Cathy A ^a   Beverley, Peter C L ^b   Brett, Sara J ^a   Britten, Christopher J ^a   Tite, John P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b EDWARD JENNER INST FOR VACC RES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 4; L SELECTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; HELPER CELL; INFLAMMATION; LYMPHATIC SYSTEM; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE MIGRATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION;

ADJUVANTS, IMMUNOLOGIC; AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; HEAT; INTERLEUKIN-12; L-SELECTIN; LISTERIA MONOCYTOGENES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; TH1 CELLS; TH2 CELLS; TRANSCRIPTION, GENETIC;

EID: 0033179609     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Swain, S. L., M. Croft, C. Dubey, L. Haynes, P. Rogers, X. Zhang, and L.M. Bradley. 1996. From naive to memory T cells. Immunol. Rev. 150:143.
2. MacDonald, H. R., R. C. Budd, and J. C. Cerottini. 1990. Pgp-1 (Ly 24) as a marker of murine memory T lymphocytes. Curr. Top. Microbiol. Immunol. 159:97.
3. Budd, R. C., J. C. Cerottini, C. Horvath, C. Bron, T. Pedrazzini, R. C. Howe, and H. R. MacDonald. 1987. Distinction of virgin and memory T lymphocytes:stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol. 138:3120.
4. Jung, T. M., W. M. Gallatin, I. L. Weissman, and M. O. Dailey. 1988. Down-regulation of homing receptors after T cell activation. J. Immunol. 141:4110.
5. + T cells from young and aged mice. J. Immunol. 145:1295.
6. + T cells after alloantigen exposure. Immunology 75:632.
7. + memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J. Immunol. 148:324.
8. Gallatin, W. M., I. L. Weissman, and E. C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304:30.
9. Geoffroy, J. S., and S. D. Rosen. 1989. Demonstration that a lectin-like receptor (gp90 mel) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes. J. Cell Biol. 109:2463.
10. Bradley, L. M., S. R. Watson, and S. L. Swain. 1994. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J. Exp. Med. 180:2401.
11. Warnock, R. A., S. Askari, E. C. Butcher, and U. H. Von Andrian. 1998. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes. J. Exp. Med. 187:205.
12. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration:the multistep paradigm. Cell 76:301.
13. Kraal, G., and R. E. Mebius. 1997. High endothelial venules:lymphocyte traffic control and controlled traffic. Adv. Immunol. 65:347.
14. Ager, A. 1997. Regulation of lymphocyte migration into lymph nodes by high endothelial venules. Biochem. Soc. Trans. 25:421.
15. Arbones, M. L., D. C. Ord, K. Ley, H. Ratech, C. Maynard-Curry, G. Otten, D. J. Capon, and T. F. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity 1:247.
16. Tedder, T. F., D. A. Steeber, A. Chen, and P. Engel. 1995. The selecting:vascular adhesion molecules. FASEB J. 9:866.
17. 2 integrins on naive peripheral lymphocytes. J. Exp. Med. 184: 1343.
18. Lawrence, M. B., and T. A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates:distinction from and prerequisite for adhesion through integrins. Cell 65:859.
19. 2 integrins in vivo. Proc. Natl. Acad. Sci. USA 88:7538.
20. Meeusen, E. N., R. R. Premier, and M. R. Brandon. 1996. Tissue-specific migration of lymphocytes:a key role for Th1 and Th2 cells? Immunol. Today 17:421.
21. Salmi, M., and S. Jalkanen. 1997. How do lymphocytes know where to go: current concepts and enigmas of lymphocyte homing. Adv. Immunol. 64:139.
22. Bradley, L. M., and S. R. Watson. 1996. Lymphocyte migration into tissue:the paradigm derived from CD4 subsets. Curr. Opin. Immunol. 8:312.
23. + cells of memory phenotype. Eur. J. Immunol. 27:2225.
24. Farber, D. L., O. Acuto, and K. Bottomly. 1997. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur. J. Immunol. 27:2094.
25. Carter, L. L., X. Zhang, C. Dubey, P. Rogers, L. Tsui, and S. L. Swain. 1998. Regulation of T cell subsets from naive to memory. J. Immunother. 21:181.
26. Croft, M., L. M. Bradley, and S. L. Swain. 1994. Naive versus memory CD4 T cell response to antigen:memory cells are less dependent on accessory cell co-stimulation and can respond to many antigen-presenting cell types including resting B cells. J. Immunol. 152:2675.
27. Bradley, L. M., K. Yoshimoto, and S. L. Swain. 1995. The cytokines IL-4, IFNγ, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. J. Immunol. 155:1713.
28. + T cells. Annu. Rev. Immunol. 12:635.
29. Carter, L. L., and R. W. Dutton. 1996. Type 1 and type 2:a fundamental dichotomy for all T-cell subsets. Curr. Opin. Immunol. 8:336.
30. Gollob, J. A., H. Kawasaki, and J. Ritz. 1997. Interferon-γ and interleukin-4 regulate T cell interleukin-12 responsiveness through the differential modulation of high-affinity interleukin-12 receptor expression. Eur. J. Immunol. 27:647.
31. Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells:different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
32. + T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547.
33. low thymocytes in vivo. Science 250:1720.
34. + T helper cell phenotype development in a T cell receptor-αβ-transgenic model. J. Exp. Med. 182:1579.
35. Murphy, E., K. Shibuya, N. Hosken, P. Openshaw, V. Maino, K. Davis, K. Murphy, and A. O'Garra. 1996. Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J. Exp. Med. 183:901.
36. Robinson, D., K. Shibuya, A. Mui, F. Zonin, E. Murphy, T. Sana, S. B. Hartley, S. Menon, R. Kastelein, F. Bazan, and A. O'Garra. 1997. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NFκB. Immunity 7:571.
37. Openshaw, P., E. E. Murphy, N. A. Hosken, V. Maino, K. Davis, Murphy K, and A. O'Garra. 1995. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J. Exp. Med 182: 1357.
38. Manetti, R., P. Parronchi, M. G. Giudizi, M. P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 177:1199.
39. Trinchieri, G. 1997. Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN-γ). Curr. Opin. Immunol. 9:17.
40. McRae, B. L., L. J. Picker, and G. A. van Seventer. 1997. Human recombinant interferon-β influences T helper subset differentiation by regulating cytokine secretion pattern and expression of homing receptors. Eur. J. Immunol. 27:2650.
41. Tripp, C. S., O. Kanagawa, and E. R. Unanue. 1995. Secondary response to listeria infection requires IFN-γ but is partially independent of IL-12. J. Immunol. 155:3427.
42. + T cells from αβTCR transgenic mice:IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent. Int. Immunol. 5:1119.
43. Wenner, C. A., M. L. Guler, S. E. Macatonia, A. O'Garra, and K. M. Murphy. 1996. Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-1 development. J. Immunol. 156:1442.
44. Bradley, L. M., D. K. Dalton, and M. Croft. 1996. A direct role for IFN-γ in regulation of Th1 cell development. J. Immunol. 157:1350.
45. Nakamura, T., R. K. Lee, S. Y. Nam, E. R. Podack, K. Bottomly, and R. A. Flavell. 1997. Roles of 1L-4 and IFN-γ in stabilizing the T helper cell type 1 and 2 phenotype. J. Immunol 158:2648.
46. Szabo, S. J., A. S. Dighe, U. Gubler, and K. M. Murphy. 1997. Regulation of the interleukin (IL)-12Rβ-2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817.
47. + T cells to enhance priming for imerferon γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90:10188.
48. Jacobson, N. G., S. J. Szabo, R. M. Weber-Nordt, Z. Zhong, R. D. Schreiber, J. E. Darnell, Jr., and K. M. Murphy. 1995. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J. Exp. Med. 181:1755.
49. Kaplan, M. H., Y. L. Sun, T. Hoey, and M. J. Grusby. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174.
50. Rogge, L., D. D'Ambriosio, M. Biffi, G. Penna, L. J. Minetti, D. Presky, L. Adorini and F. Sinigaglia. 1998. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J. Immunol. 161:6567.
51. Chao, C. C., R. Jensen, and M. O. Dailey. 1997. Mechanisms of L-selectin regulation by activated T cells. J. Immunol. 159:1686.
52. Migaki, G. I., J. Kahn, and T. K. Kishimoto. 1995. Mutational analysis of the membrane-proximal cleavage site of L-selectin:relaxed sequence specificity surrounding the cleavage site. J. Exp. Med. 182:549.
53. Preece, G., G. Murphy, and A. Ager. 1996. Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. J. Biol. Chem. 271:11634.
54. Li, X. Y., G. Matsuzaki, Y. Yoshikai, K. Muramori, and K. Nomoto. 1993. T cells expressing both L-selectin and CD44 molecules increase in number in peritoneal exudate cells and in vitro-stimulated spleen cells from mice immunized intraperitoneally with Listeria monocytogenes. Immunology 78:28.
55. Wallace, D. L., and P. C. Beverley. 1993. Characterization of a novel subset of T cells from human spleen that lacks L-selectin. Immunology 78:623.
56. + T cells. Immunology 87:186.
57. Tang, M. L., D. A. Steeber, X. Q. Zhang, and T. F. Tedder. 1998. Intrinsic differences in L-selectin expression levels affect T and B lymphocyte subset-specific re-circulation pathways. J. Immunol. 160:5113.
58. Borges, E., W. Tietz, M. Steegmaier, T. Moll, R. Hallmann, A. Hamann, and D. Vestweber. 1997. P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin. J. Exp Med. 185:573.
59. Fuhlbrigge, R. C., J. D. Kieffer, D. Armerding, and T. S. Kupper. 1997. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homingT cells. Nature 389:978.
60. van Wely, C. A., A. D. Blanchard, and C. J. Britten. 1998. Differential expression of α3 fucosyltransferases in Th1 and Th2 cells correlates with their ability to bind P-selectin. Biochem. Biophys. Res. Commun. 247:307.
61. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005.
62. Tedder, T. F., D. A. Steeber, and P. Pizcueta. 1995. L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181: 2259.
63. Austrup, F., D. Vestweber, E. Borges, M. Lohning, R. Brauer, U. Herz, H. Renz, R. Hallmann, A. Scheffold, A. Radbruch, and A. Hamann. 1997. P-and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385:81.
64. Tang, M. L., L. P. Hale, D. A. Steeber, and T. F. Tedder. 1997. L-selectin is involved in lymphocyte migration to sites of inflammation in the skin:delayed rejection of allografts in L-selectin-deficient mice. J. Immunol. 158:5191.