The binding site for an inhibitor of squalene:hopene cyclase determined using photoaffinity labeling and molecular modeling

Chemistry and Biology

Volumn 6, Issue 6, 1999, Pages 333-341

  Tongyun, Dang ^a   Ikuro, Abe ^a,b   Yi Feng, Zheng ^a   Glenn D, Prestwich ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Active site mapping; Benzophenone; Enzyme inhibitor; Triterpene biosynthesis

Indexed keywords

BIOSYNTHESIS; ENZYME INHIBITOR; MOLECULAR AND CELLULAR STRUCTURE; PHOTOAFFINITY LABELING; SQUALENE HOPENE CYCLASE;

ALICYCLOBACILLUS ACIDOCALDARIUS; BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 0033150533     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(99)80045-3     Document Type: Article

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