Cyclization of (3S)29-methylidene-2,3-oxidosqualene by bacterial squalene:hopene cyclase: Irreversible enzyme inactivation and isolation of an unnatural dammarenoid

Journal of the American Chemical Society

Volumn 119, Issue 46, 1997, Pages 11333-11334

  Abe, I ^a   Dang, T ^a   Zheng, Y F ^a   Madden, B A ^a   Fei, C ^a   Poralla, K ^a   Prestwich, G D ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLASE; DAMMARANE DERIVATIVE; RECOMBINANT ENZYME; SQUALENE DERIVATIVE; UNCLASSIFIED DRUG;

AFFINITY LABELING; ARTICLE; BINDING SITE; CYCLIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SUBSTRATE; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SITE DIRECTED MUTAGENESIS; THERMOPHILIC BACTERIUM;

EID: 0030710635     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja972770p     Document Type: Article

References (16)