Mechanism-based inhibitors and other active-site targeted inhibitors of oxidosqualene cyclase and squalene cyclase

Journal of Enzyme Inhibition

Volumn 13, Issue 6, 1998, Pages 385-398

  Abe, Ikuro ^a   Zheng, Yi Feng ^a   Prestwich, Glenn D ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Cation mimics; Cholesterol biogenesis; Covalent modification; Photoaffinity label; Polyolefin cyclization; Suicide substrate

Indexed keywords

AMINO ACID; CHOLESTEROL; LANOSTEROL SYNTHASE; POLYOLEFIN; SQUALENE; SQUALENE CYCLASE; SQUALENE DERIVATIVE; STEROL; SUICIDE SUBSTRATE; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL; BACTERIUM; BIOGENESIS; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MODIFICATION; FUNGUS; PLANT; PRIORITY JOURNAL; REVIEW; STEREOCHEMISTRY;

ANIMALIA; BACTERIA (MICROORGANISMS); FUNGI;

EID: 0031793802     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.3109/14756369809020544     Document Type: Review

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