Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies: A specific conformational change may be required for full-length receptor signaling

Journal of Biological Chemistry

Volumn 273, Issue 9, 1998, Pages 5307-5314

  Rowlinson, Scott W ^a,d   Behncken, Stuart N ^a   Rowland, Jennifer E ^a   Clarkson, Richard W ^a,e   Strasburger, Christian J ^b   Wu, Zida ^b   Baumbach, William ^c   Waters, Michael J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c PFIZER INC   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONFORMATIONAL TRANSITION; DIMERIZATION; HORMONE RECEPTOR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PEPTIDE FRAGMENTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-FOS; RABBITS; RATS; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RECEPTORS, SOMATOTROPIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS);

EID: 0032570710     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.9.5307     Document Type: Article

References (46)

1. Waters, M. J. (1997) in Handbook of Physiology (Kostyo, J. L., ed) Vol. 5, Oxford University Press, in press
2. Cunningham, B. C., Ultsch, M., Abraham, M., DeVos, A. M., Mulkerrin, M. G., Clauser, K. R., and Wells, J. A. (1991) Science 254, 821-825
3. De Vos, A. M., Ultsch, M., and Kossiakoff, A. A. (1992) Science 255, 306-312
4. Fuh, G., Cunningham, B. C., Fukunaga, R., Nagata, S., Goeddel, D. V., and Wells, J. A. (1992) Science 256, 1677-1680
5. Chen, C.-M., Brinkworth, R., and Waters, M. J. (1997) J. Biol. Chem. 272, 5133-5140
6. Lim, L., and Waters, M. J. (1990) Horm. Metab. Res. 22, 153-156
7. Rowlinson, S. W., Behncken, S. N., Brinkworth, R., and Waters, M. J. (1996) Proc. X Int. Congr. Endocrinol. (San Francisco) 2, 334
8. Rowlinson, S. W., Barnard, R., Bastiras, S., Robins, A. J., Brinkworth, R., and Waters, M. J. (1995) J. Biol. Chem. 270, 16833-16839
9. Ishizaka-Ikeda, E., Fukunaga, R., Wood, W. I., Goeddel, D. V., and Nagata, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 123-127
10. Rowlinson, S. W., Lewis, U. J., Waters, M. J., and Barnard, R. (1998) Endocrinology 137, 90-95
11. Baumbach, W. R., Horner, D. L., Logan, J. S. (1989) Genes Dev. 3, 1199-1205
12. Barnard, R., Bundesen, P., Rylatt, D., and Waters, M. J. (1984) Endocrinology 115, 1805-1813
13. Barnard, R., and Waters, M. J. (1986) J. Recept. Res. 6, 209-225
14. Barnard, R., Bundesen, P. G., Rylatt, D. B., and Waters, M. J. (1985) Biochem. J. 231, 459-468
15. Wu, Z., Strasburger, C. J. (1996) Proc. X Int. Congr. Endocrinol. (San Francisco) 2, 337
16. Wu, Z., Pflaum, C.-D., Skriver, L., Strasburger, C. J. (1996) Proc. X Int. Congr. Endocrinol. (San Francisco) 2, 338
17. Jin, L., Fendley, B. M., and Wells, J. A. (1992) J. Mol. Biol. 226, 851-865
18. Gobius, K. S., Rowlinson, S. W., Barnard, R., Mattick, J. S., and Waters, M. J. (1992) J. Mol. Endocrinol. 9, 213-220
19. Laemmli, U. K. (1970) Nature 227, 680-685
20. Mossmann, T. (1983) J. Immunol. Methods 65, 55-63
21. Chen, C., Clarkson, R. W. E., Xie Y., Hume, D. A., and Waters, M. J. (1995) Endocrinology 136, 4505-4516
22. Deleted in proof
23. Clarkson, R. W. E., Chen, C. M., Harrison, S., Wells, C., Muscat, G. E. O., and Waters, M. J. (1995) Mol. Endocrinol. 9, 108-121
24. Wegenka, U. M., Buschmann, J., Lutticken, C., Heinrich, P. C., and Horn, F. (1993) Mol. Cell. Biol. 13, 276-288
25. Barnard, R., Quirk, P., and Waters, M. J. (1989) J. Endocrinol. 123, 327-332
26. Kahn, C. R., Baird, K. L., Flier, J. S., Grunfield, C., Harmon, J. T., Harrison, L. C., Karlsson, F. A., Kasuga, M., King, G. L., Lang, U. C., Podskalny, J. M., and Obberghen, E. V. (1981) Rec. Prog. Horm. Res. 37, 477-538
27. Volpe, R. (1978) J. Clin. Endocrinol. Metab. 7, 3-29
28. Valle, A., Zuber, C. E., Defrance, T., Djossou, O., De Rie, M., and Bancheraeu, J. (1989) Eur. J. Immunol. 19, 1463-1467
29. Schreurs, J., Sugawara, M., Arai, K.-I., Ohta, Y., and Miyajima, A. (1989) J. Immunol. 142, 819-825
30. Winkler, M. E., O'Conner, L., Winget, M., and Fendley, B. (1989) Biochemistry 28, 6373-6378
31. Cheatham, B., and Kahn, C. R. (1995) Endocr. Rev. 16, 117-142
32. Xiong, L., Kasuya, J., Li, S. L., Kato, J., Fujita-Yamaguchi, J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5356-5360
33. Boutin, J. M., Jolicoeur, C., Okamura, H., Gagnon, J., Edery, M., Shirota, M., Banville, D., Dusanter-Fourt, I., Djiane, J., and Kelly, P. A. (1988) Cell 53, 69-77
34. Waters, M. J., Spencer, S. A., Hamlin, G., Henzel, W. J., and Wood, W. I. (1990) Int. J. Biochem. 22, 1089-1095
35. Fuh, G., Colosi, P., Wood, W. I., and Wells, J. A. (1993) J. Biol. Chem. 268, 5376-5381
36. Elberg, G., Kelly, P. A., Djiane, J., Binder, L., and Gertler, A. (1990) J. Biol. Chem. 265, 14770-14776
37. Rui, H., Lebrun, J. J., Kirken, R. A., Kelly, P. A., and Farrar, W. L. (1994) Endocrinology 135, 1299-1306
38. Djiane, J., Dusanter-Fourt, I., Katoh, M., and Kelly, P. A. (1985) J. Biol. Chem. 260, 11430-11435
39. Duquesnoy, P., Sobrier, M.-L., Duriez, B., Dastot, F., Buchanan, C. R., Savage, M. O., Preece, M. A., Craescu, T., Blouquit, Y., Goossens, M., and Amselem, S. (1994) EMBO J. 13, 1386-1395
40. Elliott, S., Lorenzini, T., Yanagihara, D., Chang, D., and Elliott, G. (1996) J. Biol. Chem, 271, 24691-24697
41. Argetsinger, L. S., Campbell, G. S., Yang, X.-J., Witthuhn, B. A., Silvennoinen, O., Ihle, J. N., and Carter-Su, C. (1993) Cell 74, 237-244
42. Mellado, M., Rodriguez-Frade, J. M., Kremer, L., Von Kobbe, C., Martin de Ana, A., Merida, I., and Martinez-A, C. (1997) J. Biol. Chem. 272, 9189-96
43. Wang, B. S., Lumanglas, A. A., Bona, C. A., and Moran, T. M. (1996) Mol. Cell. Endocrinol. 116, 223-226
44. Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., Johnson, D. L., Barrett, R. W., Jolliffe, L. K., and Dower, W. J. (1996) Science 273, 458-464
45. Livnah, O., Stura, E. A., Johnson, D. L., Middleton, S. A., Mulcahy, L. S., Wrighton, N. C., Dower, W. J., Jolliffe, L. K., and Wilson, I. (1996) Science 273, 464-471
46. Behncken, S. N., Rowlinson, S. W., Rowland, J. E., Conway-Campbell, B. L., Monks, T. A., and Waters, M. J. (1997) J. Biol. Chem. 272, 27077-27083