Dimerization of granulocyte-colony stimulating factor receptor: The Ig plus CRH construct of granulocyte-colony stimulating factor receptor forms a 2:2 complex with a ligand

Journal of Biochemistry

Volumn 121, Issue 2, 1997, Pages 370-375

  Horan, Thomas P ^a   Martin, Frank ^a   Simonet, Lizette ^a   Arakawa, Tsutomu ^a   Philo, John S ^a  

^a AMGEN INC   (United States)

Author keywords

Dimerization; G CSF receptor; Receptor purification; Sedimentation equilibrium

Indexed keywords

CYTOKINE RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN;

ANIMAL CELL; ARTICLE; CHO CELL; DIMERIZATION; LIGAND BINDING; MODEL; NONHUMAN; RECEPTOR AFFINITY; SEQUENCE HOMOLOGY; STOICHIOMETRY;

ANIMALIA; ESCHERICHIA COLI; INSECTA; MURINAE;

EID: 0031051275     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021597     Document Type: Article

References (14)

1. Horan, T., Wen, J., Narhi, L., Parker, V., Garcia, A., Arakawa, T., and Philo, J. (1996) Dimerization of the extracellular domain of granulocyte-colony stimulating factor receptor by ligand binding: A monovalent ligand induces 2:2 complexes. Biochemistry 35, 4886-4896
2. Fukunaga, R., Seto, Y., Mizushima, S., and Nagata, S. (1990) Three different mRNAs encoding human granulocyte colony-stimulating factor receptor. Proc. Natl. Acad. Sci. USA 87, 8702-8706
3. Fukunaga, R., Ishizaka-Ikeda, E., Seto, Y., and Nagata, S. (1990) Expression cloning of a receptor for murine granulocyte colony-stimulating factor. Cell 61, 341-350
4. Nagata, S. and Fukunaga, R. (1991) Granulocyte colony-stimulating factor and its receptors. Prog. Growth Factor Res. 3, 131-141
5. Haniu, M., Horan, T., Arakawa, T., Le, J., Katta, V., Hara, S., and Rohde, M.F. (1996) Disulfide structure and N-glycosylation sites of an extracellular domain of granulocyte-colony stimulating factor receptor. Biochemistry 35, 13040-13046
6. Hiraoka, O., Anaguchi, H., Yamasaki, G., Fukunaga, R., Nagata, S., and Ota, Y. (1994) Ligand binding domain of granulocyte colony-stimulating factor receptor. J. Biol. Chem. 269, 22412-22419
7. Hiraoka, O., Anaguchi, H., and Ota, T. (1994) Evidence for the ligand-induced conversion from a dimer to a tetramer of the granulocyte colony stimulating factor receptor. FEBS Lett. 356, 255-260
8. Hiraoka, O., Anaguchi, H., and Ota, Y. (1995) Formation of 1:1 complex of the cytokine receptor homologous region of granulocyte colony-stimulating factor receptor with ligand. Biosci. Biotech. Biochem. 59, 2351-2354
9. Anaguchi, H., Hiraoka, O., Yamasaki, K., Naito, S., and Ota, Y. (1995) Ligand binding characteristics of the carboxy-terminal domain of the cytokine receptor homologous region of the granulocyte colony-stimulating factor receptor. J. Biol. Chem. 270, 27845-27851
10. Fukunaga, R., Ishizaka-Ikeda, E., Pan, C.-X., Seto, Y., and Nagata, S. (1991) Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J. 10, 2855-2865
11. DeClerck, Y.A., Yean, T.-D., Lu, H.-S., Ting, J., and Langley, K.L. (1991) Inhibition of autoproteolytic activation of interstitial procollagenase by recombinant metalloproteinase inhibitor MI/ TIMP-2. J. Biol Chem. 266, 3893-3899
12. Wigler, M., Silverstein, S., Lee, L.S., Pellicer, A., Chang, Y.C., and Axel, R. (1977) Transfer of purified Herpes virus thymidine kinase gene to cultured mouse cells. Cell 11, 223-232
13. Hiraoka, O., Anaguchi, H., Asakura, A., and Ota, Y. (1995) Requirements for one immunoglobulin domain of granulocyte colony-stimulating factor-receptor in formation of a 2/1 receptor ligand complex. J. Biol. Chem. 270, 25928-25934
14. Reidhar-Olson, J.F., De Souza-Hart, J.A., and Selick, H. (1996) Identification of residues critical to the activity of human granulocyte colony-stimulating factor. Biochemistry 35, 9034-9041