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Volumn 18, Issue 3, 1999, Pages 644-653

Degradation of p27(Kip) cdk inhibitor triggered by Kaposi's sarcoma virus cyclin-cdk6 complex

Author keywords

Cyclin; HHV8; KSHV; p27(Kip); Phosphorylation; Protein degradation

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; PROTEIN P27; THREONINE;

EID: 0033081619     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.3.644     Document Type: Article
Times cited : (162)

References (51)
  • 1
    • 0030989155 scopus 로고    scopus 로고
    • Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1
    • Aktas, H., Cai, H. and Cooper, G.M. (1997) Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. Mol. Cell. Biol., 17, 3850-3857.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3850-3857
    • Aktas, H.1    Cai, H.2    Cooper, G.M.3
  • 2
    • 0032030615 scopus 로고    scopus 로고
    • Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice
    • Boshoff, C. et al. (1998) Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice. Blood, 91, 1671-1679.
    • (1998) Blood , vol.91 , pp. 1671-1679
    • Boshoff, C.1
  • 3
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • Boyle, W.J., van der Geer, P. and Hunter, T. (1991) Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol., 201, 110-149.
    • (1991) Methods Enzymol. , vol.201 , pp. 110-149
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 5
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • Cesarman, E., Chang, Y., Moore, P.S., Said, J.W. and Knowles, D.M. (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med., 332, 1186-1191.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 6
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang, Y., Cesarman, E., Pessin, M.S., Lee, F., Culpepper, J., Knowles, D.M. and Moore, P.S. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science, 266, 1865-1869.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5    Knowles, D.M.6    Moore, P.S.7
  • 7
    • 0031440272 scopus 로고    scopus 로고
    • Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development
    • Chellappan, S.P., Giordano, A. and Fisher, P.B. (1998) Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development. Curr. Top. Microbiol. Immunol., 227, 57-103.
    • (1998) Curr. Top. Microbiol. Immunol. , vol.227 , pp. 57-103
    • Chellappan, S.P.1    Giordano, A.2    Fisher, P.B.3
  • 8
    • 14444268041 scopus 로고    scopus 로고
    • Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
    • Esposito, V. et al. (1997) Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res., 57, 3381-3385.
    • (1997) Cancer Res. , vol.57 , pp. 3381-3385
    • Esposito, V.1
  • 9
    • 0030056036 scopus 로고    scopus 로고
    • Establishment of AIDS-relatcd lymphoma cell lines from lymphomatous effusions
    • Gaidano, G., Cechova, K., Chang, Y., Moore, P.S., Knowles, D.M. and Dalla, F.R. (1996) Establishment of AIDS-relatcd lymphoma cell lines from lymphomatous effusions. Leukemia, 10, 1237-1240.
    • (1996) Leukemia , vol.10 , pp. 1237-1240
    • Gaidano, G.1    Cechova, K.2    Chang, Y.3    Moore, P.S.4    Knowles, D.M.5    Dalla, F.R.6
  • 10
    • 0030992885 scopus 로고    scopus 로고
    • The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastomaprotein and histone H1
    • Godden Kent, D., Talbot, S.J., Boshoff, C., Chang, Y., Moore, P., Weiss, R.A. and Mittnacht, S. (1997) The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastomaprotein and histone H1. J. Virol., 71, 4193-4198.
    • (1997) J. Virol. , vol.71 , pp. 4193-4198
    • Godden Kent, D.1    Talbot, S.J.2    Boshoff, C.3    Chang, Y.4    Moore, P.5    Weiss, R.A.6    Mittnacht, S.7
  • 11
    • 0003448569 scopus 로고    scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Harlow, E. and Lane, D. (1998) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1998) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 12
    • 0030991235 scopus 로고    scopus 로고
    • The retinoblastoma protein: A master regulator of cell cycle, differentiation and apoptosis
    • Herwig, S. and Strauss, M. (1997) The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis. Eur. J. Biochem., 246, 581-601.
    • (1997) Eur. J. Biochem. , vol.246 , pp. 581-601
    • Herwig, S.1    Strauss, M.2
  • 13
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh, J.K., Fredersdorf, S., Kouzarides, T., Martin, K. and Lu, X. (1997) E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev., 11, 1840-1852.
    • (1997) Genes Dev. , vol.11 , pp. 1840-1852
    • Hsieh, J.K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 14
    • 0025773123 scopus 로고
    • Cyclins and cancer
    • Hunter, T. and Pines, J. (1991) Cyclins and cancer. Cell, 66, 1071-1074.
    • (1991) Cell , vol.66 , pp. 1071-1074
    • Hunter, T.1    Pines, J.2
  • 15
    • 0030863161 scopus 로고    scopus 로고
    • Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
    • Kawada, M., Yamagoe, S., Murakami, Y., Suzuki, K., Mizuno, S. and Uehara, Y. (1997) Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway. Oncogene, 15, 629-637.
    • (1997) Oncogene , vol.15 , pp. 629-637
    • Kawada, M.1    Yamagoe, S.2    Murakami, Y.3    Suzuki, K.4    Mizuno, S.5    Uehara, Y.6
  • 17
    • 0031936668 scopus 로고    scopus 로고
    • Ras versus cyclin-dependent kinase inhibitors
    • Lloyd, A.C. (1998) Ras versus cyclin-dependent kinase inhibitors. Curr. Opin. Genet. Dev., 8, 43-18.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 43-118
    • Lloyd, A.C.1
  • 18
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda, M., Cukor, B., Tam, S.W., Lavin, P., Fiorentino, M., Draetta, G.F., Jessup, J.M. and Pagano, M. (1997) Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Med., 3, 231-234.
    • (1997) Nature Med. , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3    Lavin, P.4    Fiorentino, M.5    Draetta, G.F.6    Jessup, J.M.7    Pagano, M.8
  • 19
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg, A.S. and Weinberg, R.A. (1998) Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol., 18, 753-761.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 20
    • 0029670376 scopus 로고    scopus 로고
    • Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells
    • Mal, A., Poon, R.Y., Howe, P.H., Toyoshima, H., Hunter, T. and Harter, M.L. (1996) Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells. Nature, 380, 262-265.
    • (1996) Nature , vol.380 , pp. 262-265
    • Mal, A.1    Poon, R.Y.2    Howe, P.H.3    Toyoshima, H.4    Hunter, T.5    Harter, M.L.6
  • 21
    • 0031037714 scopus 로고    scopus 로고
    • Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
    • Meijer, L., Borgne, A., Mulner, O., Chong, J.P., Blow, J.J., Inagaki, N., Inagaki, M., Delcros, J.G. and Moulinoux, J.P. (1997) Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem., 243, 527-536.
    • (1997) Eur. J. Biochem. , vol.243 , pp. 527-536
    • Meijer, L.1    Borgne, A.2    Mulner, O.3    Chong, J.P.4    Blow, J.J.5    Inagaki, N.6    Inagaki, M.7    Delcros, J.G.8    Moulinoux, J.P.9
  • 22
    • 0030753686 scopus 로고    scopus 로고
    • Chemical inhibitors of cyclin-dependent kinases
    • Meijer, L. and Kim, S.H. (1997) Chemical inhibitors of cyclin-dependent kinases. Methods Enzymol., 283, 113-128.
    • (1997) Methods Enzymol. , vol.283 , pp. 113-128
    • Meijer, L.1    Kim, S.H.2
  • 23
    • 0030808947 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors in human neoplasms
    • Miller, C.W. and Koeffler, H.P. (1997) Cyclin-dependent kinase inhibitors in human neoplasms. Leukemia, 3, 370-371.
    • (1997) Leukemia , vol.3 , pp. 370-371
    • Miller, C.W.1    Koeffler, H.P.2
  • 24
    • 0031935648 scopus 로고    scopus 로고
    • Control of pRB phosphorylation
    • Mittnacht, S. (1998) Control of pRB phosphorylation. Curr. Opin. Genet. Dev., 8, 21-27.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 21-27
    • Mittnacht, S.1
  • 25
    • 0031979151 scopus 로고    scopus 로고
    • Antiviral activity of tumour suppressor pathways: Clues from molecular piracy by KSHV
    • Moore, P.S. and Chang, Y. (1998) Antiviral activity of tumour suppressor pathways: clues from molecular piracy by KSHV. Trends Genet., 14, 144-150.
    • (1998) Trends Genet. , vol.14 , pp. 144-150
    • Moore, P.S.1    Chang, Y.2
  • 26
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D.O. (1995) Principles of CDK regulation. Nature, 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 27
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks and microprocessors
    • Morgan, D.O. (1997) Cyclin-dependent kinases: engines, clocks and microprocessors. Annu. Rev. Cell Dev. Biol., 13, 261-291.
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 30
    • 0029974841 scopus 로고    scopus 로고
    • Primary effusion lymphoma: A distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus
    • Nador, R.G., Cesarman, E., Chadburn, A., Dawson, D.B., Ansari, M.Q., Said, J. and Knowles, D.M. (1996) Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood, 88, 645-656.
    • (1996) Blood , vol.88 , pp. 645-656
    • Nador, R.G.1    Cesarman, E.2    Chadburn, A.3    Dawson, D.B.4    Ansari, M.Q.5    Said, J.6    Knowles, D.M.7
  • 31
    • 0029855312 scopus 로고    scopus 로고
    • Perturbation of cell cycle regulators in human cancer
    • Palmero, I. and Peters, G. (1996) Perturbation of cell cycle regulators in human cancer. Cancer Surv., 27, 351-367.
    • (1996) Cancer Surv. , vol.27 , pp. 351-367
    • Palmero, I.1    Peters, G.2
  • 32
    • 0030909148 scopus 로고    scopus 로고
    • Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27 (Kip1) binding to newly formed complexes
    • Perez, R.I., Solomon, D.L., Sewing, A. and Land, H. (1997) Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27 (Kip1) binding to newly formed complexes. Oncogene, 14, 2373-2381.
    • (1997) Oncogene , vol.14 , pp. 2373-2381
    • Perez, R.I.1    Solomon, D.L.2    Sewing, A.3    Land, H.4
  • 33
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K., Kato, J.Y., Solomon, M.J., Sherr, C.J., Massagué, J., Roberts, J.M. and Koff, A. (1994) p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8, 9-22.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massagué, J.5    Roberts, J.M.6    Koff, A.7
  • 34
    • 0031048716 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
    • Porter, P.L., Malone, K.E., Heagerty, P.J., Alexander, G.M., Gatti, L.A., Firpo, E.J., Daling, J.R. and Roberts, J.M. (1997) Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nature Med., 3, 222-225.
    • (1997) Nature Med. , vol.3 , pp. 222-225
    • Porter, P.L.1    Malone, K.E.2    Heagerty, P.J.3    Alexander, G.M.4    Gatti, L.A.5    Firpo, E.J.6    Daling, J.R.7    Roberts, J.M.8
  • 35
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir, I., Polyak, K., Iavarone, A. and Massagué, J. (1995) Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev., 9, 1831-1845.
    • (1995) Genes Dev. , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massagué, J.4
  • 36
    • 0031883550 scopus 로고    scopus 로고
    • Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1)
    • Sarid, R., Flore, O., Bohenzky, R.A., Chang, Y. and Moore, P.S. (1998) Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1). J. Virol., 72, 1005-1012.
    • (1998) J. Virol. , vol.72 , pp. 1005-1012
    • Sarid, R.1    Flore, O.2    Bohenzky, R.A.3    Chang, Y.4    Moore, P.S.5
  • 38
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C.J. (1996) Cancer cell cycles. Science, 274, 1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 39
    • 0029800256 scopus 로고    scopus 로고
    • Evidence of gene deletion of p21 (WAF1/C1P1), a cyclin-dependent protein kinase inhibitor, in thyroid carcinomas
    • Shi, Y., Zou, M., Farid, N.R. and Al, S.S. (1996) Evidence of gene deletion of p21 (WAF1/C1P1), a cyclin-dependent protein kinase inhibitor, in thyroid carcinomas. Br. J. Cancer, 74, 1336-1341.
    • (1996) Br. J. Cancer , vol.74 , pp. 1336-1341
    • Shi, Y.1    Zou, M.2    Farid, N.R.3    Al, S.S.4
  • 42
    • 0030697223 scopus 로고    scopus 로고
    • Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins
    • Swanton, C. Mann, D.J., Fleckenstein, B., Neipel, F., Peters, G. and Jones, N. (1997) Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature, 390, 184-187.
    • (1997) Nature , vol.390 , pp. 184-187
    • Swanton, C.1    Mann, D.J.2    Fleckenstein, B.3    Neipel, F.4    Peters, G.5    Jones, N.6
  • 43
    • 0030740210 scopus 로고    scopus 로고
    • 1 phase required for p27kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
    • 1 phase required for p27kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell. Biol., 17, 5348-5358.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5348-5358
    • Takuwa, N.1    Takuwa, Y.2
  • 44
    • 0030894787 scopus 로고    scopus 로고
    • The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas
    • Tan, P., Cady, B., Wanner, M., Worland, P., Cukor, B., Magi, G.C., Lavin, P., Draetta, G., Pagano, M. and Loda, M. (1997) The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res., 57, 1259-1263.
    • (1997) Cancer Res. , vol.57 , pp. 1259-1263
    • Tan, P.1    Cady, B.2    Wanner, M.3    Worland, P.4    Cukor, B.5    Magi, G.C.6    Lavin, P.7    Draetta, G.8    Pagano, M.9    Loda, M.10
  • 45
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • Van den Heuvel, S. and Harlow, E. (1993) Distinct roles for cyclin-dependent kinases in cell cycle control. Science, 262, 2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van Den Heuvel, S.1    Harlow, E.2
  • 46
    • 0030847760 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
    • Vlach, J., Hennecke, S. and Amati, B. (1997) Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J., 16, 5334-5344.
    • (1997) EMBO J. , vol.16 , pp. 5334-5344
    • Vlach, J.1    Hennecke, S.2    Amati, B.3
  • 47
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R.A. (1995) The retinoblastoma protein and cell cycle control. Cell, 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 50
    • 0030443870 scopus 로고    scopus 로고
    • Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein
    • Zerfass, T.K., Zwerschke, W., Mannhardt, B., Tindle, R., Botz, J.W. and Jansen, D.P. (1996) Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene, 13, 2323-2330.
    • (1996) Oncogene , vol.13 , pp. 2323-2330
    • Zerfass, T.K.1    Zwerschke, W.2    Mannhardt, B.3    Tindle, R.4    Botz, J.W.5    Jansen, D.P.6
  • 51
    • 0029957833 scopus 로고    scopus 로고
    • Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma
    • Zhong, W., Wang, H., Herndier, B. and Ganem, D. (1996) Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc. Natl Acad. Sci. USA, 93, 6641-6646.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6641-6646
    • Zhong, W.1    Wang, H.2    Herndier, B.3    Ganem, D.4


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