The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1

Journal of Virology

Volumn 71, Issue 6, 1997, Pages 4193-4198

  Godden Kent, Diana ^a   Talbot, Simon J ^a   Boshoff, Chris ^a   Chang, Yuan ^b   Moore, Patrick ^b   Weiss, Robin A ^a   Mittnacht, Sibylle ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; HISTONE H1; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HERPES VIRUS; KAPOSI SARCOMA; LEPIDOPTERA; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE;

EID: 0030992885     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.6.4193-4198.1997     Document Type: Article

References (59)

1. Ambroziak, J. A., D. J. Blackbourn, B. G. Herndier, R. G. Glogau, J. H. Gullett, A. R. McDonald, E. T. Lennette, and J. A. Levy. 1995. Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science 268:582-583.
2. Arvanitakis, L., N. Yaseen, and S. Sharma. 1995. Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-beta 1-mediated growth inhibition in EBV-positive B cells. J. Immunol. 155:1047-1056.
3. 1. Genes Dev. 7:812-821.
4. Bates, S., L. Bonetta, D. MacAllan, D. Parry, A. Holder, C. Dickson, and G. Peters. 1994. CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1. Oncogene 9:71-79.
5. Bates, S., and G. Peters. 1995. Cyclin D1 as a cellular proto-oncogene. Semin. Cancer Biol. 6:73-82.
6. Beral, V. 1991. Epidemiology of Kaposi's sarcoma. Cancer Surv. 10:5-22.
7. Bodrug, S. E., B. J. Warner, M. L. Bath, G. J. Lindeman, A. W. Harris, and J. M. Adams. 1994. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J. 13:2124-2130.
8. 7a. Boshoff, C. Unpublished data.
9. Boshoff, C., T. F. Schulz, M. M. Kennedy, A. K. Graham, C. Fisher, A. Thomas, J. O. McGee, R. A. Weiss, and J. J. O'Leary. 1995. Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nat. Med. 1:1274-1278.
10. Boshoff, C., D. Whitby, T. Hatziioannou, C. Fisher, J. Van der Walt, A. Hatzakis, R. Weiss, and T. Schulz. 1995. Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma. Lancet 345:1043-1044.
11. Cesarman, E., Y. Chang, P. S. Moore, J. W. Said, and D. M. Knowles. 1995. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332:1186-1191.
12. Cesarman, E., R. G. Nador, F. Bai, R. A. Bohenzky, J. J. Russo, Y. Chang, P. S. Moore, and D. Knowles. 1996. Kaposi's sarcoma-associated herpesvirus (KSHV) contains G-protein coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma. J. Virol. 70: 8218-8223.
13. Chang, Y., E. Cesarman, M. S. Pessin, F. Lee, J. Culpepper, D. M. Knowles, and P. S. Moore. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1865-1869.
14. Chang, Y., P. S. Moore, S. J. Talbot, C. H. Boshoff, T. Zarkowska, D. Godden-Kent, H. Paterson, R. A. Weiss, and S. Mittnacht. 1996. Cyclin encoded by KS herpesvirus. Nature 382:410.
15. Decker, L. L., P. Shankar, G. Khan, R. B. Freeman, B. J. Dezube, J. Lieberman, and L. D. Thorley. 1996. The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients. J. Exp. Med. 184: 283-288.
16. Doerner, P., J. E. Jorgensen, R. You, J. Steppuhn, and C. Lamb. 1996. Control of root growth and development by cyclin expression. Nature 380: 520-523.
17. Doonan, J., and T. Hunt. 1996. Cell cycle. Why don't plants get cancer? Nature 380:481-482.
18. Dupin, N., M. Grandadam, V. Calvez, I. Gorin, J. T. Aubin, S. Havard, F. Lamy, M. Leibowitch, J. M. Huraux, J. P. Escande, et al. 1995. Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. Lancet 345:761-762.
19. Dyson, N., and E. Harlow. 1992. Adenovirus E1A targets key regulators of cell proliferation. Cancer Surv. 12:161-195.
20. Harper, J. W., S. J. Elledge, K. Keyomarsi, B. Dynlach, L. H. Tsai, P. Zhan, S. Dobrowolski, C. Bai, L. Connell-Crowley, and E. Swindel. 1995. Inhibition of cyclin dependent kinases by p21. Mol. Cell. Biol. 6:387-400.
21. Hunter, T., and J. Pines. 1994. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 79:573-582.
22. Jacks, T., and R. A. Weinberg. 1996. Cell-cycle control and its watchman. Nature 381:643-644.
23. Jansen-Durr, P. 1996. How viral oncogenes make the cell cycle. Trends Genet. 12:270-275.
24. Jung, J. U., M. Stager, and R. C. Desrosiers. 1994. Virus-encoded cyclin. Mol. Cell. Biol. 14:7235-7244.
25. Kedes, D. H., E. Operskalski, M. Busch, R. Kohn, J. Flood, and D. Ganem. 1996. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat. Med. 2:918-924.
26. Lennette, E. T., D. J. Blackbourne, and J. A. Levy. 1996. Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 348:858-861.
27. Lopata, M. A., D. W. Cleveland, and W. B. Sollner. 1984. High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. Nucleic Acids Res. 12:5707-5717.
28. Lovec, H., A. Grzeschiczek, M. B. Kowalski, and T. Moroy. 1994. Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J. 13:3487-3495.
29. Maridor, G., P. Gallant, R. Golsteyn, and E. A. Nigg. 1993. Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. J. Cell Sci. 106:535-544.
30. 1 cyclins. Cell 71:323-334.
31. Matsushime, H., D. E. Quelle, S. A. Shurtleff, M. Shibuya, C. J. Sherr, and J. Y. Kato. 1994. D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol. 14:2066-2076.
32. Mesri, E. A., E. Cesarman, L. Arvanitakis, S. Rafii, P. A. Moore, D. N. Posnell, and A. S. Asch. 1996. Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. J. Exp. Med. 183:2385-2390.
33. Meyerson, M., G. H. Enders, C. L. Wu, L. K. Su, C. Gorka, C. Nelson, E. Harlow, and L. H. Tsai. 1992. A family of human cdc2-related protein kinases. EMBO J. 11:2909-2917.
34. 1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14:2077-2086.
35. Miller, G., M. O. Rigsby, L. Heston, E. Grogan, R. Sun, C. Metroka, J. A. Levy, S. J. Gao, Y. Chang, and P. Moore. 1996. Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. N. Engl. J. Med. 334:1292-1297.
36. Moore, P. S., C. Boshoff, R. A. Weiss, and Y. Chang. 1996. Molecular mimicry of human cytokine and cytokine-response pathway genes by KSHV. Science 274:1739-1744.
37. Moore, P. S., S. J. Gao, G. Dominguez, E. Cesarman, O. Lungu, D. M. Knowles, R. Garber, P. E. Pellett, D. J. McGeoch, and Y. Chang. 1996. Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J. Virol. 70:549-558.
38. Moore, P. S., and Y. Chang. 1995. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N. Engl. J. Med. 332:1181-1185.
39. Morgan, D. O. 1995. Principles of CDK regulation. Nature 374:131-134.
40. Nicholas, J., K. R. Cameron, and R. W. Honess. 1992. Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins. Nature 355:362-365.
41. 1-to-S phase transition. Mol. Cell. Biol. 15:2612-2624.
42. Peters, G. 1994. The D-type cyclins and their role in tumorigenesis. J. Cell Sci. Suppl. 18:89-96.
43. Polyak, K., J. Y. Kato, M. J. Solomon, C. J. Sherr, J. Massague, J. M. Roberts, and A. Koff. 1994. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev. 8:9-22.
44. Polyak, K., M. H. Lee, B. H. Erdjument, A. Koff, J. M. Roberts, P. Tempst, and J. Massague. 1994. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
45. Renne, R., W. Zhong, B. Herndier, M. McGrath, N. Abbey, D. Kedes, and D. Ganem. 1996. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat. Med. 2:342-346.
46. 1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol. 14:1669-1679.
47. Russo, J. J., R. A. Bohenzky, M. C. Chien, J. Chen, M. Yan, D. Maddalena, J. P. Parry, D. Peruzzi, I. S. Edelman, Y. Chang, and P. S. Moore. 1996. Sequence of the Kaposi's sarcoma-associated herpesvirus. Proc. Natl. Acad. Sci. USA 93:14862-14867.
48. Sarid, R., T. Sato, R. Bohenzky, J. Russo, and Y. Chang. 1997. Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a functional bcl-2 homolog. Nat. Med. 3:293-298.
49. Schalling, M., M. Ekman, E. E. Kaaya, A. Linde, and P. Biberfeld. 1995. A role for a new herpes virus (KSHV) in different forms of Kaposi's sarcoma. Nat. Med. 1:705-706.
50. 1 phase progression: cycling on cue. Cell 79:551-555.
51. Sherr, C. J. 1995. D-type cyclins. Trends Biochem. Sci. 20:187-190.
52. Simpson, G. R., T. F. Schulz, D. Whitby, P. M. Cook, C. Boshoff, L. Rainbow, M. Howard, S. J. Gao, R. A. Bohenzky, P. Simmonds, C. Lee, A. de Ruiter, A. Hatzakis, and R. S. Tedder. 1996. Prevalence of Kaposi's sarcoma-associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 348:1133-1137.
53. 1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO J. 13:3321-3328.
54. Toyoshima, H., and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74.
55. Wang, T. C., R. D. Cardiff, L. Zukerberg, E. Lees, A. Arnold, and E. V. Schmidt. 1994. Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369:669-671.
56. Weiss, R. A. 1990. The conundrum of Kaposi's sarcoma. Eur. J. Cancer 26:657-659.
57. Xiong, Y., H. Zhang, and D. Beach. 1992. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71:505-514.
58. Zarkowska, T., S. U., E. Harlow, and S. Mittnacht. 1997. Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs. Oncogene 14: 249-254.
59. Zhong, W., H. Wang, B. Herndier, and D. Ganem. 1996. Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc. Natl. Acad. Sci. USA 93:6641-6646.