Gene therapy for malignant gliomas

Hematology/Oncology Clinics of North America

Volumn 12, Issue 3, 1998, Pages 617-629

  Alavi, J B ^a   Eck, S L ^a  

^a Stellar Chance Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CARMUSTINE; CYTARABINE; FAMCICLOVIR; FLUCYTOSINE; FLUDARABINE; GANCICLOVIR;

ANTINEOPLASTIC ACTIVITY; DRUG DELIVERY SYSTEM; EXPRESSION VECTOR; GENE TARGETING; GENE THERAPY; GLIOBLASTOMA; HUMAN; IMMUNOTHERAPY; PRIORITY JOURNAL; REVIEW;

EID: 0031819012     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8588(05)70011-3     Document Type: Article

References (45)

1. S.S. Andreansky B. He G.Y. Gillespie The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors Proc Natl Acad Sci USA 93 1996 11313 11318
2. A. Asai Gene therapy for brain tumors: Induction of apoptosis and immunogenic modulation in glioma cells No Shinkei Geka 23 1995 7 15
3. B. Badie K.E. Drazan M.H. Kramar Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats Neurol Res 17 1995 209 216
4. J. Banchereau R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252
5. J.R. Bischoff D.H. Kirn A. Williams An adenovirus mutant that replicates selectively in p53-deficient human tumor cells Science 274 1996 373 376
6. R. Chambers G.Y. Gillespie L. Soroceanu Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma Proc Natl Acad Sci USA 92 1995 1411 1415
7. J. Chen T. Willingham M. Shuford Effects of ectopic overexpression of p21 (WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells Oncogene 13 1996 1395 1403
8. E.A. Chiocca Brain tumor gene therapy in mice with a novel “suicide” gene: The cyclophosphamide-activating CYP2B1 gene Clin Neurosurg 42 1995 370 382
9. K.W. Culver Gene therapy for malignant neoplasms of the CNS Bone Marrow Transplant 18 suppl 1996 S6 S9
10. P.Y. Dietrich P.R. Walker P. Saas Immunobiology of gliomas: New perspectives for therapy Ann NY Acad Sci 824 1997 124 140
11. S.L. Eck J.B. Alavi A. Alavi Clinical protocol: Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial Hum Gene Ther 7 1996 1465 1482
12. S.L. Eck J.M. Wilson Gene-Based Therapy Hardman J.G. Limbird L.E. Goodman & Gilman's: The Pharmacological Basis of Therapeutics 1995 McGraw-Hill New York 77 102
13. A.A. Elshami A. Saavedra H. Zhang Gap junctions play a role in the `bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro Gene Ther 3 1996 85 92
14. H. Fakhrai O. Dorigo D.L. Shawler Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy Proc Natl Acad Sci USA 93 1996 2909 2914
15. S. Freeman C.N. Abboud K.A. Whartenby The “bystander effect”: Tumor regression when a fraction of the tumor mass is genetically modified Cancer Res 53 1993 5274 5283
16. K. Ge L. Xu Z. Zheng Transduction of cytosine deaminase gene makes rat glioma cells highly sensitive to 5-fluorocytosine Int J Cancer 7 1997 675 679
17. R.P. Glick T. Lichtor A. Mogharbel Intracerebral versus subcutaneous immunization with allogeneic fibroblasts genetically engineered to secrete interleukin-2 in the treatment of central nervous system glioma and melanoma Neurosurgery 41 1997 898 906
18. M. Hsiao V. Tse J. Carmel Intracavitary liposome-mediated p53 gene transfer into glioblastoma with endogenous wild-type p53 in vivo results in tumor suppression and long-term survival Biochem Biophysi Res Commun 233 1997 359 364
19. E. Ikeda M.G. Achen G. Breier Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells J Biol Chem 270 1995 19761 19766
20. M. Izquierdo M.L. Cortes V. Martin Gene therapy in brain tumours: Implications of the size of glioblastoma on its curability Acta Neurol Scand Suppl 68 1997 111 117
21. M. Izquierdo V. Martin de Felipe P. Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy Gene Ther 3 1996 491 495
22. S.H. Kim J.H. Kim A. Kolozsvary Preferential radiosensitization of 9L glioma cells transduced with HSV-tk gene by acyclovir J Neurooncol 33 1997 189 194
23. D.W. Laske R.J. Youle E.H. Oldfield Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors Nat Med 3 1997 1362 1368
24. Y. Manome P.Y. Wen L. Chen Gene therapy for malignant gliomas using replication incompetent retroviral and adenoviral vectors encoding the cytochrome P450 2B1 gene together with cyclophosphamide Gene Ther 3 1996 513 520
25. B.D. Minsky The role of adjuvant therapy in the treatment of colorectal cancer Hematol Oncol Clin North Am 11 1997 679 697
26. S. Miyatake R.L. Martuza S.D. Rabkin Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma Cancer Gene Ther 4 1997 222 228
27. F. Moolten Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy Cancer Res 46 1986 5276 5281
28. G. Nilaver L.L. Muldoon R.A. Kroll Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption Proc Natl Acad Sci USA 92 1995 9829 9833
29. E. Peltekian E. Parrish C. Bouchard Adenovirus-mediated gene transfer to the brain: Methodological assessment J Neurosci Methods 71 1997 77 84
30. K.H. Plate Gene therapy of malignant glioma via inhibition of tumor angiogenesis Cancer Metastasis Rev 15 1996 237 240
31. K.H. Plate W. Risau Angiogenesis in malignant gliomas Glia 15 1995 339 347
32. Z. Ram K.W. Culver E.M. Oshiro Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells Nat Med 3 1997 1354 1361
33. G.J. Redekop C.C. Naus Transfection with bFGF sense and antisense cDNA resulting in modification of malignant glioma growth J Neurosurg 82 1995 83 90
34. M. Saleh S.A. Stacker A.F. Wilks Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence Cancer Res 56 1996 393 401
35. J.H. Sampson D.A. Ashley G.E. Archer Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion Neurosurgery 41 1997 1365 1373
36. D. Shweiki A. Itin D. Soffer Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-induced angiogenesis Nature 359 1992 845 848
37. J.G. Smith S.E. Raper E. Wheeldon Intracranial administration of adenovirus expressing HSVTK in combination with ganciclovir produces a self-limited, dose-dependent inflammatory response Hum Gene Ther 8 1997 943 954
38. R.E. Sobol H. Fakhrai D. Shawler Interleukin-2 gene therapy in a patient with glioblastoma Gene Ther 2 1995 164 167
39. T. Tanaka Y. Manome P. Wen Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth Nat Med 3 1997 437 442
40. J. Tjuvajev B. Gansbacher R. Desai RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma Cancer Res 55 1995 1902 1910
41. Q.T. Trinh E.A. Austin D.M. Murray Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line Cancer Res 55 1995 4808 4812
42. S.H. Tseng L.H. Hwang S.M. Lin Induction of antitumor immunity by intracerebrally implanted rat C6 glioma cells genetically engineered to secrete cytokines J Immunother 20 1997 334 342
43. S. Valtonen U. Timonen P. Toivanen Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: A randomized double-blind study Neurosurgery 41 1997 44 48
44. A.J. Vincent M.C. Esandi C.J. Avezaat Preclinical testing of recombinant adenoviral herpes simplex virus-thymidine kinase gene therapy for central nervous system malignancies Neurosurgery 41 1997 442 451
45. J. Zhu L. Zhang U.K. Hanisch A continuous intracerebral gene delivery system for in vivo liposome-mediated gene therapy Gene Ther 3 1996 472 476