-
1
-
-
0026556434
-
Bioregulation of kinins: Kallikreins, kininogens and kininases
-
Bhoola KD, Figueroa CD, Worthy K. Bioregulation of kinins: kallikreins, kininogens and kininases. Pharmacol Rev 1992;44:4-80.
-
(1992)
Pharmacol Rev
, vol.44
, pp. 4-80
-
-
Bhoola, K.D.1
Figueroa, C.D.2
Worthy, K.3
-
2
-
-
0018995127
-
Pharmacology of bradykinin and related kinins
-
Regoli D, Barabé J. Pharmacology of bradykinin and related kinins. Pharmacol Rev 1980;32:1-46.
-
(1980)
Pharmacol Rev
, vol.32
, pp. 1-46
-
-
Regoli, D.1
Barabé, J.2
-
3
-
-
0026760390
-
Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene
-
Eggerickx D, Raspe E, Bertrand D, Vassart G, Parmentier M. Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene. Biochem Biophys Res Commun 1992;187:1306-13.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 1306-1313
-
-
Eggerickx, D.1
Raspe, E.2
Bertrand, D.3
Vassart, G.4
Parmentier, M.5
-
4
-
-
0026721649
-
Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor
-
Hess JF, Borkowski JA, Young GS, Strader CD, Ransom RW. Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor. Biochem Biophys Res Commun 1992;184:260-8.
-
(1992)
Biochem Biophys Res Commun
, vol.184
, pp. 260-268
-
-
Hess, J.F.1
Borkowski, J.A.2
Young, G.S.3
Strader, C.D.4
Ransom, R.W.5
-
5
-
-
0028065140
-
Expression cloning of a human B1 bradykinin receptor
-
Menke JG, Borkowski JA, Bierilo KK, et al. Expression cloning of a human B1 bradykinin receptor. J Biol Chem 1994;2698:21583-6.
-
(1994)
J Biol Chem
, vol.2698
, pp. 21583-21586
-
-
Menke, J.G.1
Borkowski, J.A.2
Bierilo, K.K.3
-
6
-
-
0003009788
-
Kinin B1 receptor induction and inflammation
-
Farmer SG, (Ed.). London: Academic Press
-
Marceau F. Kinin B1 receptor induction and inflammation. In: Farmer SG, (Ed.). The kinin system. London: Academic Press, 1997:143-156.
-
(1997)
The Kinin System
, pp. 143-156
-
-
Marceau, F.1
-
7
-
-
0028065140
-
Expression cloning of a human B1 bradykinin receptor
-
Menke JG, Borkowski JA, Bierilo KK, et al. Expression cloning of a human B1 bradykinin receptor. J Biol Chem 1994;269:21583-6.
-
(1994)
J Biol Chem
, vol.269
, pp. 21583-21586
-
-
Menke, J.G.1
Borkowski, J.A.2
Bierilo, K.K.3
-
8
-
-
0030943729
-
Stable expression of the human kinin B1 receptor in Chinese hamster ovary cells
-
Austin CE, Faussner A, Robinson HE, et al. Stable expression of the human kinin B1 receptor in Chinese hamster ovary cells. J Biol Chem 1997;272:11420-5.
-
(1997)
J Biol Chem
, vol.272
, pp. 11420-11425
-
-
Austin, C.E.1
Faussner, A.2
Robinson, H.E.3
-
9
-
-
0002930001
-
Regulation of bradykinin action at the receptor level
-
Roscher AA, Klier C, Dengler D, Faussner A, Müller-Esterl W. Regulation of bradykinin action at the receptor level. J Cardiovasc Pharmacol 1990;15:S39-43.
-
(1990)
J Cardiovasc Pharmacol
, vol.15
-
-
Roscher, A.A.1
Klier, C.2
Dengler, D.3
Faussner, A.4
Müller-Esterl, W.5
-
10
-
-
0032579389
-
Influence of the cytosolic carboxyl termini of human B1 and B 2 receptors on receptor sequestration, ligand internalization, and signal transduction
-
Faussner A, Proud D, Towns M, Bathon JM. Influence of the cytosolic carboxyl termini of human B1 and B 2 receptors on receptor sequestration, ligand internalization, and signal transduction. J Biol Chem 1998;273:2617-23.
-
(1998)
J Biol Chem
, vol.273
, pp. 2617-2623
-
-
Faussner, A.1
Proud, D.2
Towns, M.3
Bathon, J.M.4
-
12
-
-
0002530319
-
The pharmacology and immunopharmacology of kinin receptors
-
Farmer SG, (Ed.). London: Academic Press
-
Hall JM, Morton IKM. The pharmacology and immunopharmacology of kinin receptors. In: Farmer SG, (Ed.). The kinin system. London: Academic Press, 1997:9-44.
-
(1997)
The Kinin System
, pp. 9-44
-
-
Hall, J.M.1
Morton, I.K.M.2
-
13
-
-
0025969299
-
Hoe 140 a new potent and long acting bradykinin-antagonist: In vitro studies
-
Hock FJ, Wirth K, Albus U, et al. Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies. Br J Pharmacol 1991;102:769-73.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 769-773
-
-
Hock, F.J.1
Wirth, K.2
Albus, U.3
-
14
-
-
20244363204
-
Hoe 140 a new potent and long acting bradykinin-antagonist: In vivo studies
-
Wirth K, Hock FJ, Albus U, et al. Hoe 140 a new potent and long acting bradykinin-antagonist: in vivo studies. Br J Pharmacol 1991;102:774-7.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 774-777
-
-
Wirth, K.1
Hock, F.J.2
Albus, U.3
-
15
-
-
0001894437
-
The kallikrein-kinin system in asthma and acute respiratory distress syndrome
-
Farmer SG, (Ed.). London: Academic Press
-
Farmer SG. The kallikrein-kinin system in asthma and acute respiratory distress syndrome. In: Farmer SG, (Ed.). The kinin system. London: Academic Press, 1997:249-264.
-
(1997)
The Kinin System
, pp. 249-264
-
-
Farmer, S.G.1
-
16
-
-
0004967295
-
Putative role of bradykinin and the kinin system in pancreatitis
-
Farmer SG, (Ed.). London: Academic Press
-
Griesbacher T, Lembeck F. Putative role of bradykinin and the kinin system in pancreatitis. In: Farmer SG, (Ed.). The kinin system. London: Academic Press, 1997:197-218.
-
(1997)
The Kinin System
, pp. 197-218
-
-
Griesbacher, T.1
Lembeck, F.2
-
17
-
-
0010420598
-
Bradykinin as an inflammatory mediator in the urinary tract
-
Farmer SG, editor. London: Academic Press
-
Maggi CA. Bradykinin as an inflammatory mediator in the urinary tract. In: Farmer SG, editor. The kinin system. London: Academic Press, 1997:235-248.
-
(1997)
The Kinin System
, pp. 235-248
-
-
Maggi, C.A.1
-
18
-
-
0000761899
-
Structure based drug design: Progress toward the discovery of the elusive bradykinin receptor antagonists
-
Kyle DJ. Structure based drug design: progress toward the discovery of the elusive bradykinin receptor antagonists. Curr Pharm Des 1995;1:233-54.
-
(1995)
Curr Pharm Des
, vol.1
, pp. 233-254
-
-
Kyle, D.J.1
-
19
-
-
0344820093
-
-
PCT international patent application WO 98 24809, publ. date 11 June 1998
-
Dodey P, Luccarini J-M, Martinez J, Amblard M, Daffix I. Pseudopeptide agonists of bradykinin B2 receptors - for treating cardiovascular disorders and promoting passage through the blood brain barrier. PCT international patent application WO 98 24809, publ. date 11 June 1998.
-
Pseudopeptide Agonists of Bradykinin B2 Receptors - For Treating Cardiovascular Disorders and Promoting Passage Through the Blood Brain Barrier
-
-
Dodey, P.1
Luccarini, J.-M.2
Martinez, J.3
Amblard, M.4
Daffix, I.5
-
20
-
-
0344388408
-
-
Ger Patent DE 19546938, publ. date 19 June 1997
-
Wagner A, Breipohl G, Heitsch H, Gerhards H, Noelken G, Wirth K, Schölkens B. Preparation of tri- and tetrapeptides as bradykinin antagonists. Ger Patent DE 19546938, publ. date 19 June 1997.
-
Preparation of Tri- and Tetrapeptides as Bradykinin Antagonists
-
-
Wagner, A.1
Breipohl, G.2
Heitsch, H.3
Gerhards, H.4
Noelken, G.5
Wirth, K.6
Schölkens, B.7
-
21
-
-
0002100465
-
Nonpeptide bradykinin antagonists
-
Burch RM, editor. New York: Marcel Dekker
-
Calixto JB, Yunes RA, Rae GA, Medeiros YS. Nonpeptide bradykinin antagonists. In: Burch RM, editor. Bradykinin antagonists, basic and clinical research. New York: Marcel Dekker, 1990:97-129.
-
(1990)
Bradykinin Antagonists, Basic and Clinical Research
, pp. 97-129
-
-
Calixto, J.B.1
Yunes, R.A.2
Rae, G.A.3
Medeiros, Y.S.4
-
22
-
-
0003117128
-
A survey of bradykinin receptors and their antagonists
-
Kyle DJ, Burch RM. A survey of bradykinin receptors and their antagonists. Curr Opin Invest Drugs 1993;2:5-20.
-
(1993)
Curr Opin Invest Drugs
, vol.2
, pp. 5-20
-
-
Kyle, D.J.1
Burch, R.M.2
-
23
-
-
0027220896
-
Design of potent nonpeptide competitive antagonists of the human bradykinin B2 receptor
-
Salvino JM, Seoane PR, Douty BD, et al. Design of potent nonpeptide competitive antagonists of the human bradykinin B2 receptor. J Med Chem 1993;36:2583-4.
-
(1993)
J Med Chem
, vol.36
, pp. 2583-2584
-
-
Salvino, J.M.1
Seoane, P.R.2
Douty, B.D.3
-
25
-
-
0028890972
-
Structure-activity relationships of non-peptide bradykinin B2 receptor antagonists
-
Salvino JM, Seoane PR, Douty BD, et al. Structure-activity relationships of non-peptide bradykinin B2 receptor antagonists. BioOrg Med Chem Lett 1995;5:357-62.
-
(1995)
BioOrg Med Chem Lett
, vol.5
, pp. 357-362
-
-
Salvino, J.M.1
Seoane, P.R.2
Douty, B.D.3
-
26
-
-
0028229872
-
The nonpeptide WIN 64338 is a bradykinin B2 receptor antagonist
-
Sawutz DG, Salvino JM, Dolle RE, et al. The nonpeptide WIN 64338 is a bradykinin B2 receptor antagonist. Proc Natl Acad Sci USA 1994;91:4693-7.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4693-4697
-
-
Sawutz, D.G.1
Salvino, J.M.2
Dolle, R.E.3
-
27
-
-
0028886333
-
Pharmacology and structure activity relationships of the nonpeptide bradykinin receptor antagonist WIN 64338
-
Sawutz DG, Salvino JM, Dolle RE, Seoane PR, Farmer SG. Pharmacology and structure activity relationships of the nonpeptide bradykinin receptor antagonist WIN 64338. Can J Physiol Pharmacol 1995;73:805-11.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 805-811
-
-
Sawutz, D.G.1
Salvino, J.M.2
Dolle, R.E.3
Seoane, P.R.4
Farmer, S.G.5
-
28
-
-
0000603111
-
Conformational analysis of bradykinin by annealed molecular dynamics and comparison to NMR derived conformations
-
Salvino JM, Seoane PR, Dolle RE. Conformational analysis of bradykinin by annealed molecular dynamics and comparison to NMR derived conformations. J Comput Chem 1993;14:438-44.
-
(1993)
J Comput Chem
, vol.14
, pp. 438-444
-
-
Salvino, J.M.1
Seoane, P.R.2
Dolle, R.E.3
-
29
-
-
0028860711
-
Kinin receptor antagonists: Unique probes in basic and clinical research
-
Wirth KJ, Heitsch H, Schölkens BA. Kinin receptor antagonists: unique probes in basic and clinical research. Can J Physiol Pharmacol 1995;73:797-804.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 797-804
-
-
Wirth, K.J.1
Heitsch, H.2
Schölkens, B.A.3
-
30
-
-
0030603860
-
Bradykinin receptors and receptor ligands (with special emphasis on vascular receptors)
-
Regoli D, Calò G, Rizzi A, et al. Bradykinin receptors and receptor ligands (with special emphasis on vascular receptors). Regul Pept 1996;65:83-9.
-
(1996)
Regul Pept
, vol.65
, pp. 83-89
-
-
Regoli, D.1
Calò, G.2
Rizzi, A.3
-
32
-
-
0022507416
-
Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. a divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types
-
Klutchko S, Blankley CJ, Fleming RW, et al. Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types. J Med Chem 1986;29:1953-61.
-
(1986)
J Med Chem
, vol.29
, pp. 1953-1961
-
-
Klutchko, S.1
Blankley, C.J.2
Fleming, R.W.3
-
33
-
-
0030852693
-
Nonpeptide bradykinin antagonist analogs based on a model of a Sterling Winthrop nonpeptide bradykinin antagonists overlapped with cyclic hexapeptide bradykinin antagonist peptides
-
Dankwardt SM, Ferla S, Krstenansky JL, Bhakta S, Ostrelich H, Jarnagin K. Nonpeptide bradykinin antagonist analogs based on a model of a Sterling Winthrop nonpeptide bradykinin antagonists overlapped with cyclic hexapeptide bradykinin antagonist peptides. BioOrg Med Chem Lett 1997;7:1921-6.
-
(1997)
BioOrg Med Chem Lett
, vol.7
, pp. 1921-1926
-
-
Dankwardt, S.M.1
Ferla, S.2
Krstenansky, J.L.3
Bhakta, S.4
Ostrelich, H.5
Jarnagin, K.6
-
34
-
-
0345251291
-
-
European patent application EP 596406, publ. date 11 May 1994
-
Oku T, Kayakiri H, Satoh S, Abe Y, Sawada Y, Tanaka H. Imidazo[1,2-α]pyridines as bradykinin antagonists. European patent application EP 596406, publ. date 11 May 1994.
-
Imidazo[1,2-α]pyridines as Bradykinin Antagonists
-
-
Oku, T.1
Kayakiri, H.2
Satoh, S.3
Abe, Y.4
Sawada, Y.5
Tanaka, H.6
-
36
-
-
0344388403
-
-
PCT international patent application WO 96 13485, publ. date 9 May 1996
-
Oku T, Kayakiri H, Satoh S, Abe Y, Sawada Y, Inoue T, Tanaka H. Pyridopyrimidones, quinolines and fused N-heterocycles as bradykinin antagonists. PCT international patent application WO 96 13485, publ. date 9 May 1996.
-
Pyridopyrimidones, Quinolines and Fused N-heterocycles as Bradykinin Antagonists
-
-
Oku, T.1
Kayakiri, H.2
Satoh, S.3
Abe, Y.4
Sawada, Y.5
Inoue, T.6
Tanaka, H.7
-
37
-
-
33749727187
-
-
PCT international patent application WO 97 41104, publ. date 6 November 1997
-
Oku T, Kayakiri H, Satoh S, Abe Y, Sawada Y, Inoue T, Tanaka H. Quinoline derivatives, processes for their preparation, and their use as medicaments. PCT international patent application WO 97 41104, publ. date 6 November 1997.
-
Quinoline Derivatives, Processes for Their Preparation, and Their use as Medicaments
-
-
Oku, T.1
Kayakiri, H.2
Satoh, S.3
Abe, Y.4
Sawada, Y.5
Inoue, T.6
Tanaka, H.7
-
38
-
-
0030768697
-
Pharmacological characterization of a novel, orally active, nonpeptide bradykinin B2 receptor antagonist, FR167344
-
Inamura N, Asano M, Hatori C, et al. Pharmacological characterization of a novel, orally active, nonpeptide bradykinin B2 receptor antagonist, FR167344. Eur J Pharmacol 1997;333:79-86.
-
(1997)
Eur J Pharmacol
, vol.333
, pp. 79-86
-
-
Inamura, N.1
Asano, M.2
Hatori, C.3
-
39
-
-
0345251285
-
Discovery of a new class of non-peptide bradykinin B2 receptor antagonists with a novel framework mimicking the active conformation of the clinical candidate FR173657
-
Nov 19-21, Tsukuba, Abst 2-P-26
-
Abe Y. Discovery of a new class of non-peptide bradykinin B2 receptor antagonists with a novel framework mimicking the active conformation of the clinical candidate FR173657, 17th Symp Med Chem/6th Annu Meet Div Med Chem/2nd Conference on Drug Discovery, Nov 19-21, 1997, Tsukuba, Abst 2-P-26.
-
(1997)
17th Symp Med Chem/6th Annu Meet Div Med Chem/2nd Conference on Drug Discovery
-
-
Abe, Y.1
-
40
-
-
8044243585
-
The identification of an orally active nonpeptide bradykinin B2 receptor antagonist, FR173657
-
Asano M, Inamura N, Hatori C, et al. The identification of an orally active nonpeptide bradykinin B2 receptor antagonist, FR173657. Br J Pharmacol 1997;120:617-24.
-
(1997)
Br J Pharmacol
, vol.120
, pp. 617-624
-
-
Asano, M.1
Inamura, N.2
Hatori, C.3
-
41
-
-
0030982892
-
FR173657: A new potent nonpeptide kinin B2 receptor antagonist - An in vitro study
-
Rizzi A, Gobeil F, Calò G, Inamura N, Regoli D. FR173657: a new potent nonpeptide kinin B2 receptor antagonist - an in vitro study. Hypertension 1997;29:951-6.
-
(1997)
Hypertension
, vol.29
, pp. 951-956
-
-
Rizzi, A.1
Gobeil, F.2
Calò, G.3
Inamura, N.4
Regoli, D.5
-
42
-
-
0031037549
-
Novel subtype selective nonpeptide bradykinin receptor antagonists FR 167344 and FR 173657
-
Aramori I, Zenkoh J, Morikawa N, et al. Novel subtype selective nonpeptide bradykinin receptor antagonists FR 167344 and FR 173657. Mol Pharmacol 1997;51:171-6.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 171-176
-
-
Aramori, I.1
Zenkoh, J.2
Morikawa, N.3
-
43
-
-
0344388402
-
MEN 11270, a novel kinin B2 receptor antagonist
-
Nara, Japan, October 19-24, Abstr S-V-4
-
Meini S, Quartara L, Giolitti A, Maggi CA. MEN 11270, a novel kinin B2 receptor antagonist. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr S-V-4.
-
(1998)
The 15th International Conference on Kinins
-
-
Meini, S.1
Quartara, L.2
Giolitti, A.3
Maggi, C.A.4
-
45
-
-
15444343988
-
Pharmacological characterization of a non peptide bradykinin B2 receptor antagonist, FR 165649, and agonist, FR 190997
-
Asano M, Hatori C, Sawai H, et al. Pharmacological characterization of a non peptide bradykinin B2 receptor antagonist, FR 165649, and agonist, FR 190997. Br J Pharmacol 1998;124:441-6.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 441-446
-
-
Asano, M.1
Hatori, C.2
Sawai, H.3
-
46
-
-
0344388401
-
Characterization of the first non peptide bradykinin B2 receptor agonist; FR 190997
-
Nara, Japan, October 19-24, Abstr P-VIII-3
-
Gobeil F, Inamura N, Regoli D. Characterization of the first non peptide bradykinin B2 receptor agonist; FR 190997. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr P-VIII-3.
-
(1998)
The 15th International Conference on Kinins
-
-
Gobeil, F.1
Inamura, N.2
Regoli, D.3
-
47
-
-
4244051876
-
In vitro characterization of FR 190997, the first non peptide B2 receptor agonist. Receptor binding and bioassay in the human umbilical vein
-
13th International Congress of Pharmacology, München, Germany, July 26-31 1998, Abstr P 1512
-
Rizzi A, Rizzi C, Amadesi S, Varani K, Calò G, Inamura N, Borea PA, Regoli D. In vitro characterization of FR 190997, the first non peptide B2 receptor agonist. Receptor binding and bioassay in the human umbilical vein. 13th International Congress of Pharmacology, München, Germany, July 26-31 1998, Abstr P 1512. Arch Pharmacol 1998;358 Suppl 1:R336.
-
(1998)
Arch Pharmacol
, vol.358
, Issue.1 SUPPL.
-
-
Rizzi, A.1
Rizzi, C.2
Amadesi, S.3
Varani, K.4
Calò, G.5
Inamura, N.6
Borea, P.A.7
Regoli, D.8
-
48
-
-
0345682865
-
Anion secretory effects of a non-peptide mimic of bradykinin (FR 190997) on colon epithelium
-
Nara, Japan, October 19-24, Abstr O-VII-3
-
Cuthbert AW. Anion secretory effects of a non-peptide mimic of bradykinin (FR 190997) on colon epithelium. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr O-VII-3.
-
(1998)
The 15th International Conference on Kinins
-
-
Cuthbert, A.W.1
-
49
-
-
0344388399
-
Nonpeptide mimic of bradykinin with log-acting properties at the bradykinin B2 receptor
-
Nara, Japan, October 19-24, Abstr O-VII-2
-
Aramori I, Zenkoh J, Morikawa N, Asano M, Hatori C, Sawai H, Kayakiri H, Satoh S, Inoue T, Abe Y, Sawada Y, Mizutani T, Inamura N, Iwami N, Nakahara K, Kojo H, Oku T, Notsu Y, Hayashi I, Majima M. Nonpeptide mimic of bradykinin with log-acting properties at the bradykinin B2 receptor. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr O-VII-2.
-
(1998)
The 15th International Conference on Kinins
-
-
Aramori, I.1
Zenkoh, J.2
Morikawa, N.3
Asano, M.4
Hatori, C.5
Sawai, H.6
Kayakiri, H.7
Satoh, S.8
Inoue, T.9
Abe, Y.10
Sawada, Y.11
Mizutani, T.12
Inamura, N.13
Iwami, N.14
Nakahara, K.15
Kojo, H.16
Oku, T.17
Notsu, Y.18
Hayashi, I.19
Majima, M.20
more..
-
50
-
-
0345251281
-
FR 190997, a novel bradykinin B2 agonist expresses longer action than BK in paw edema formation and hypotensive response
-
Nara, Japan, October 19-24, Abstr O-III-5
-
Ueno A, Naraba H, Kojima F, Morita E, Oh-ishi S. FR 190997, a novel bradykinin B2 agonist expresses longer action than BK in paw edema formation and hypotensive response. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr O-III-5.
-
(1998)
The 15th International Conference on Kinins
-
-
Ueno, A.1
Naraba, H.2
Kojima, F.3
Morita, E.4
Oh-ishi, S.5
-
51
-
-
0030919924
-
Effects of an orally active nonpeptide bradykinin B2 receptor antagonist, FR173657, on plasma exudation in rat carrageenin-induced pleurisy
-
Majima M, Kawashima N, Hiroshi I, Katori M. Effects of an orally active nonpeptide bradykinin B2 receptor antagonist, FR173657, on plasma exudation in rat carrageenin-induced pleurisy. Br J Pharmacol 1997;121:723-30.
-
(1997)
Br J Pharmacol
, vol.121
, pp. 723-730
-
-
Majima, M.1
Kawashima, N.2
Hiroshi, I.3
Katori, M.4
-
52
-
-
0031002974
-
Effects of FR173657 a nonpeptide B2 antagonist, on kinin-induced hypotension, visceral and peripheral oedema formation and bronchoconstriction
-
Griesbacher T, Legat FJ. Effects of FR173657 a nonpeptide B2 antagonist, on kinin-induced hypotension, visceral and peripheral oedema formation and bronchoconstriction. Br J Pharmacol 1997;120:933-9.
-
(1997)
Br J Pharmacol
, vol.120
, pp. 933-939
-
-
Griesbacher, T.1
Legat, F.J.2
-
53
-
-
0030814857
-
Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344 on different in vivo animal models of inflammation
-
Asano M, Hatori C, Inamura N, et al. Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344 on different in vivo animal models of inflammation. Br J Pharmacol 1997;122:1436-40.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 1436-1440
-
-
Asano, M.1
Hatori, C.2
Inamura, N.3
-
54
-
-
0031595092
-
The nonpeptide B2 receptor antagonist FR173657: Inhibition of effects of bradykinin related to its role in nociception
-
Griesbacher T, Amann R, Sametz W, Diethart S, Juan H. The nonpeptide B2 receptor antagonist FR173657: inhibition of effects of bradykinin related to its role in nociception. Br J Pharmacol 1998;124:1328-34.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 1328-1334
-
-
Griesbacher, T.1
Amann, R.2
Sametz, W.3
Diethart, S.4
Juan, H.5
-
55
-
-
0345251278
-
2 receptor antagonists, FR 172357 and FR 173657
-
San Francisco, CA, April 13-17, Abstr MEDI-089
-
2 receptor antagonists, FR 172357 and FR 173657. 213th ACS National Meeting, San Francisco, CA, April 13-17, 1997, Abstr MEDI-089.
-
(1997)
213th ACS National Meeting
-
-
Abe, Y.1
Kayakiri, H.2
Satoh, S.3
Inoue, T.4
Sawada, Y.5
Oku, T.6
Tanaka, H.7
-
56
-
-
15444356141
-
A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 1. Construction of the basic framework
-
Abe Y, Kayakiri H, Satoh S, et al. A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 1. Construction of the basic framework. J Med Chem 1998;41:564-78.
-
(1998)
J Med Chem
, vol.41
, pp. 564-578
-
-
Abe, Y.1
Kayakiri, H.2
Satoh, S.3
-
57
-
-
15644374841
-
A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 2. Overcoming the species difference between guinea pig and man
-
Abe Y, Kayakiri H, Satoh S, et al. A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 2. Overcoming the species difference between guinea pig and man. J Med Chem 1998;41:4053-61.
-
(1998)
J Med Chem
, vol.41
, pp. 4053-4061
-
-
Abe, Y.1
Kayakiri, H.2
Satoh, S.3
-
58
-
-
15644367578
-
A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-α]pyridine moiety
-
Abe Y, Kayakiri H, Satoh S, et al. A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-α]pyridine moiety. J Med Chem 1998;41:4062-79.
-
(1998)
J Med Chem
, vol.41
, pp. 4062-4079
-
-
Abe, Y.1
Kayakiri, H.2
Satoh, S.3
-
59
-
-
0345682867
-
-
PCT international patent application WO 97 11069, publ. date 27 March 1997
-
Oku T, Kayakiri H, Abe Y, Sawada Y, Mizutani T. Heterocyclic compounds as bradykinin antagonists. PCT international patent application WO 97 11069, publ. date 27 March 1997.
-
Heterocyclic Compounds as Bradykinin Antagonists
-
-
Oku, T.1
Kayakiri, H.2
Abe, Y.3
Sawada, Y.4
Mizutani, T.5
-
60
-
-
33749774918
-
-
PCT international patent application WO 96 40639, publ. date 19 December 1996
-
Dodey P, Pruneau D, Paquet J-L, Bondoux M, Houziaux P, Barth M, Ou K. Benzenesulfonamide derivatives used as bradykinin antagonists. PCT international patent application WO 96 40639, publ. date 19 December 1996.
-
Benzenesulfonamide Derivatives Used as Bradykinin Antagonists
-
-
Dodey, P.1
Pruneau, D.2
Paquet, J.-L.3
Bondoux, M.4
Houziaux, P.5
Barth, M.6
Ou, K.7
-
61
-
-
33749774918
-
-
PCT international patent application WO 97 07115, publ. date 27 February 1997
-
Dodey P, Bondoux M, Houziaux P, Barth M, Ou K. Benzenesulfonamide derivatives as bradykinin antagonists. PCT international patent application WO 97 07115, publ. date 27 February 1997.
-
Benzenesulfonamide Derivatives as Bradykinin Antagonists
-
-
Dodey, P.1
Bondoux, M.2
Houziaux, P.3
Barth, M.4
Ou, K.5
-
62
-
-
33749796061
-
-
PCT international patent application WO 97 24349, publ. date 10 July 1997
-
Dodey P, Bondoux M, Houziaux P, Barth M, Ou K. 1-Benzenesulfonyl pyrrolidine derivatives as bradykinin receptor antagonists. PCT international patent application WO 97 24349, publ. date 10 July 1997.
-
1-Benzenesulfonyl Pyrrolidine Derivatives as Bradykinin Receptor Antagonists
-
-
Dodey, P.1
Bondoux, M.2
Houziaux, P.3
Barth, M.4
Ou, K.5
-
64
-
-
33749776091
-
-
PCT international patent application WO 98 24783, publ. date 11 June 1998
-
Dodey P, Bondoux M, Ou K, Barth M, Houziaux P. Novel N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use. PCT international patent application WO 98 24783, publ. date 11 June 1998.
-
Novel N-benzenesulfonyl-L-proline Derivatives, Method for Preparing and Therapeutic use
-
-
Dodey, P.1
Bondoux, M.2
Ou, K.3
Barth, M.4
Houziaux, P.5
-
65
-
-
33749710416
-
-
European patent application EP 795547, publ. date 17 September 1997
-
Heitsch H, Wagner A, Wirth K, Schölkens B, Nölkne G. (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as bradykinin receptor antagonists. European patent application EP 795547, publ. date 17 September 1997.
-
(Aminoalkyl- and Acylaminoalkyl-oxy)benzyloxyquinolines, Process for Their Preparation and use as Bradykinin Receptor Antagonists
-
-
Heitsch, H.1
Wagner, A.2
Wirth, K.3
Schölkens, B.4
Nölkne, G.5
-
66
-
-
0345251244
-
-
European patent application EP 796848, publ. date 24 September 1997
-
Wagner A, Heitsch H, Nölkne G, Wirth K, Bernard P. Fluoroalkyl- and fluoroalkoxy-substituted heterocyclic bradykinin antagonists. European patent application EP 796848, publ. date 24 September 1997.
-
Fluoroalkyl- and Fluoroalkoxy-substituted Heterocyclic Bradykinin Antagonists
-
-
Wagner, A.1
Heitsch, H.2
Nölkne, G.3
Wirth, K.4
Bernard, P.5
-
68
-
-
15644383726
-
LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B2 receptor
-
Pruneau D, Luccarini J-M, Fouchet C, et al. LF 16.0335, a novel potent and selective nonpeptide antagonist of the human bradykinin B2 receptor. Br J Pharmacol 1998;125:365-72.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 365-372
-
-
Pruneau, D.1
Luccarini, J.-M.2
Fouchet, C.3
-
69
-
-
0345251243
-
Pharmacological profile of LF 16.0687, a new potent nonpeptide bradykinin B2 receptor antagonist
-
Nara, Japan, October 19-24, Abstr P-VIII-4
-
Pruneau D, Paquet J-L, Luccarini J-M, Defrêne E, Fouchet C, Franck R-M, Loillier B, Robert C, Bélichard P, Duclos H, Cremers B, Dodey P. Pharmacological profile of LF 16.0687, a new potent nonpeptide bradykinin B2 receptor antagonist. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr P-VIII-4.
-
(1998)
The 15th International Conference on Kinins
-
-
Pruneau, D.1
Paquet, J.-L.2
Luccarini, J.-M.3
Defrêne, E.4
Fouchet, C.5
Franck, R.-M.6
Loillier, B.7
Robert, C.8
Bélichard, P.9
Duclos, H.10
Cremers, B.11
Dodey, P.12
-
70
-
-
0345564175
-
LF 16.0687, a new nonpeptide bradykinin B2 receptor antagonist, reduces cerebral edema in a rat model of closed head trauma
-
Nara, Japan, October 19-24, Abstr S-V-3
-
Pruneau D, Chorny I, Benkovitz B, Artru A, Roitblat R, Shapira Y. LF 16.0687, a new nonpeptide bradykinin B2 receptor antagonist, reduces cerebral edema in a rat model of closed head trauma. The 15th International Conference on Kinins, Nara, Japan, October 19-24, 1998, Abstr S-V-3.
-
(1998)
The 15th International Conference on Kinins
-
-
Pruneau, D.1
Chorny, I.2
Benkovitz, B.3
Artru, A.4
Roitblat, R.5
Shapira, Y.6
-
71
-
-
33749704692
-
-
European patent application EP 808838, publ. date 26 November 1997
-
Wagner A, Heitsch H, Nölkne G, Wirth K, Bernard P. Sulfur containing heterocyclic bradykinin antagonists, processes or their production and use thereof. European patent application EP 808838, publ. date 26 November 1997.
-
Sulfur Containing Heterocyclic Bradykinin Antagonists, Processes or Their Production and use Thereof
-
-
Wagner, A.1
Heitsch, H.2
Nölkne, G.3
Wirth, K.4
Bernard, P.5
-
75
-
-
0345251239
-
Solution phase combinatorial chemistry in drug discovery
-
Ischia, Italy, 29 Sept-4 Oct
-
Storer R. Solution phase combinatorial chemistry in drug discovery. 7th IASOC, Ischia Advanced School of Organic Chemistry, Ischia, Italy, 29 Sept-4 Oct 1996.
-
(1996)
7th IASOC, Ischia Advanced School of Organic Chemistry
-
-
Storer, R.1
-
76
-
-
13344287044
-
Bradykinin receptor antagonists containing N-substituted amino acids: In vitro and in vivo B2 and B1 receptor antagonist activity
-
Goodfellow VS, Marathe MV, Kuhlman KG, et al. Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B2 and B1 receptor antagonist activity. J Med Chem 1996;39:1472-84.
-
(1996)
J Med Chem
, vol.39
, pp. 1472-1484
-
-
Goodfellow, V.S.1
Marathe, M.V.2
Kuhlman, K.G.3
-
77
-
-
0030252432
-
Rationally designed non-peptides: Variously substituted piperazine libraries for the discovery of bradykinin antagonists and other G-protein coupled receptor ligands
-
Goodfellow VS, Laudeman CP, Gerrity JI, et al. Rationally designed non-peptides: variously substituted piperazine libraries for the discovery of bradykinin antagonists and other G-protein coupled receptor ligands. Mol Diversity 1996;2:97-102.
-
(1996)
Mol Diversity
, vol.2
, pp. 97-102
-
-
Goodfellow, V.S.1
Laudeman, C.P.2
Gerrity, J.I.3
-
78
-
-
0345251235
-
-
PCT international patent application WO 97 10222, publ. date 20 March 1997
-
Goodfellow VS, McLeod DA, Gerrity JI, Laudeman CP, Burkard MR. Method for preparing piperazines. PCT international patent application WO 97 10222, publ. date 20 March 1997.
-
Method for Preparing Piperazines
-
-
Goodfellow, V.S.1
McLeod, D.A.2
Gerrity, J.I.3
Laudeman, C.P.4
Burkard, M.R.5
-
79
-
-
0344388371
-
Rationally designed piperazine libraries for the discovery of bradykinin antagonists and other G-protein coupled receptor ligands
-
Washington DC, May 2-3
-
Goodfellow VS. Rationally designed piperazine libraries for the discovery of bradykinin antagonists and other G-protein coupled receptor ligands. CHI 4th Annual Conference on the Development of Small Molecule Mimetic Drugs, Washington DC, May 2-3, 1996.
-
(1996)
CHI 4th Annual Conference on the Development of Small Molecule Mimetic Drugs
-
-
Goodfellow, V.S.1
-
81
-
-
0344388369
-
-
PCT international patent application WO 96 06082, publ. date 29 February 1996
-
Ito F, Kondo H, Hageman DL, Lowe JA, Nakanishi S, Vinick FJ. Dihydropyridine derivatives as bradykinin antagonists. PCT international patent application WO 96 06082, publ. date 29 February 1996.
-
Dihydropyridine Derivatives as Bradykinin Antagonists
-
-
Ito, F.1
Kondo, H.2
Hageman, D.L.3
Lowe, J.A.4
Nakanishi, S.5
Vinick, F.J.6
-
82
-
-
33749709094
-
-
PCT international patent application WO 96 06083, publ. date 29 February 1996
-
Ito F, Kondo H, Hageman DL, Lowe JA, Nakanishi S, Vinick FJ. 2-(Piperazinyl-1-carbonylmethyl)-1,4-dihydropyridines as bradykinin antagonists. PCT international patent application WO 96 06083, publ. date 29 February 1996.
-
2-(Piperazinyl-1-carbonylmethyl)-1,4-dihydropyridines as Bradykinin Antagonists
-
-
Ito, F.1
Kondo, H.2
Hageman, D.L.3
Lowe, J.A.4
Nakanishi, S.5
Vinick, F.J.6
-
84
-
-
0344388367
-
-
US Patent US 5288725, publ. date 22 February 1994
-
Witherup KM, Ransom RW, Varga SL, Pitzenberger SM, Lotti VJ, Lumma WC. Pyrroloquinoline bradykinin antagonist. US Patent US 5288725, publ. date 22 February 1994.
-
Pyrroloquinoline Bradykinin Antagonist
-
-
Witherup, K.M.1
Ransom, R.W.2
Varga, S.L.3
Pitzenberger, S.M.4
Lotti, V.J.5
Lumma, W.C.6
-
85
-
-
0029014935
-
Martinelline and martinellic acid, novel G-protein linked receptor antagonists from the tropical plant Martinella iquitosensis (Bignoniaceae)
-
Witherup KM, Ransom RW, Graham AC, et al. Martinelline and martinellic acid, novel G-protein linked receptor antagonists from the tropical plant Martinella iquitosensis (Bignoniaceae). J Am Chem Soc 1995;117:6682-5.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 6682-6685
-
-
Witherup, K.M.1
Ransom, R.W.2
Graham, A.C.3
-
86
-
-
0000837810
-
L-755807, a new non-peptide bradykinin binding inhibitor from an endophytic Microsphaeropsis sp
-
Tony Lam YK, Hensens OD, Ransom R, Giacobbe RA, Polishook J, Zink D. L-755807, a new non-peptide bradykinin binding inhibitor from an endophytic Microsphaeropsis sp. Tetrahedron 1996;52:1481-6.
-
(1996)
Tetrahedron
, vol.52
, pp. 1481-1486
-
-
Tony Lam, Y.K.1
Hensens, O.D.2
Ransom, R.3
Giacobbe, R.A.4
Polishook, J.5
Zink, D.6
-
87
-
-
0345682834
-
-
PCT international patent application WO 97 25315, publ. date 17 July 1997
-
Ferrari B, Gougat J, Muneaux C, Muneaux Y, Perreaut P, Planchenault C. Novel N-(arylsulphonyl)amino acid derivatives having bradykinin receptor affinity. PCT international patent application WO 97 25315, publ. date 17 July 1997.
-
Novel N-(arylsulphonyl)amino Acid Derivatives Having Bradykinin Receptor Affinity
-
-
Ferrari, B.1
Gougat, J.2
Muneaux, C.3
Muneaux, Y.4
Perreaut, P.5
Planchenault, C.6
-
88
-
-
0030010048
-
Receptors for kinins in the human isolated umbilical vein
-
Gobeil F, Pheng LH, Badini I, et al. Receptors for kinins in the human isolated umbilical vein. Br J Pharmacol 1996;118:289-94.
-
(1996)
Br J Pharmacol
, vol.118
, pp. 289-294
-
-
Gobeil, F.1
Pheng, L.H.2
Badini, I.3
-
91
-
-
0026534406
-
Effect of Hoe 140, a new bradykinin receptor antagonist, on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig
-
Sakamoto T, Elwood W, Barnes PJ, Chung KF. Effect of Hoe 140, a new bradykinin receptor antagonist, on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig. Eur J Pharmacol 1992;213:367-73.
-
(1992)
Eur J Pharmacol
, vol.213
, pp. 367-373
-
-
Sakamoto, T.1
Elwood, W.2
Barnes, P.J.3
Chung, K.F.4
-
92
-
-
0028287983
-
Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin
-
Marceau F, Levesque L, Drapeau G, et al. Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin. J Pharmacol Exp Ther 1994;269:1136-43.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 1136-1143
-
-
Marceau, F.1
Levesque, L.2
Drapeau, G.3
-
93
-
-
0028102504
-
Bradykinin receptor types and B2 subtypes
-
Regoli D, Gobeil F, Nguyen QT, et al. Bradykinin receptor types and B2 subtypes. Life Sci 1994;55:735-49.
-
(1994)
Life Sci
, vol.55
, pp. 735-749
-
-
Regoli, D.1
Gobeil, F.2
Nguyen, Q.T.3
-
94
-
-
0030715723
-
Characterization of FR173657, a novel nonpeptide B2 antagonist: In vitro and in vivo studies
-
Inamura N, Asano M, Kayakiri H, Hatori C, Oku T, Nakahara K. Characterization of FR173657, a novel nonpeptide B2 antagonist: in vitro and in vivo studies. Can J Physiol Pharmacol 1997;75:622-8.
-
(1997)
Can J Physiol Pharmacol
, vol.75
, pp. 622-628
-
-
Inamura, N.1
Asano, M.2
Kayakiri, H.3
Hatori, C.4
Oku, T.5
Nakahara, K.6
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