Rationally designed non-peptides: Variously substituted piperazine libraries for the discovery of bradykinin antagonists and other G-protein-coupled receptor ligands

Molecular Diversity

Volumn 2, Issue 1-2, 1996, Pages 97-102

  Goodfellow, Val S ^a   Laudeman, Chris P ^a   Gerrity, J I ^a   Burkard, Michael ^a   Strobel, Eric ^a   Zuzack, John S ^a   McLeod, Don A ^a  

^a Departments of New Leads Chemistry and Pharmacology   (United States)

Author keywords

Bradykinin antagonist; Combinatorial chemistry; Libraries; Piperazine; Piperazinedione

Indexed keywords

ALUMINUM DERIVATIVE; ALUMINUM LITHIUM HYDRIDE; AMINE; BRADYKININ; CELL SURFACE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; LITHIUM DERIVATIVE; PEPTIDE LIBRARY; PIPERAZINE DERIVATIVE; REDUCING AGENT;

ACETYLATION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; SYNTHESIS;

ACETYLATION; ALUMINUM COMPOUNDS; AMINES; BRADYKININ; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DESIGN; GTP-BINDING PROTEINS; HUMANS; LIGANDS; LITHIUM COMPOUNDS; MODELS, MOLECULAR; PEPTIDE LIBRARY; PIPERAZINES; RECEPTORS, CELL SURFACE; REDUCING AGENTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0030252432     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01718706     Document Type: Article

References (12)

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