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Volumn 41, Issue 21, 1998, Pages 4062-4079

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-a]pyridine moiety

Author keywords

[No Author keywords available]

Indexed keywords

3 (6 ACETAMIDO 3 PYRIDYL) N [N [2,4 DICHLORO 3 [(2 METHYL 8 QUINOLINYL)OXYMETHYL]PHENYL] N METHYLAMINOCARBONYLMETHYL]ACRYLAMIDE; 3 BROMO 8 [2,6 DICHLORO 3 [N [4 (N,N DIMETHYLCARBAMOYL)CINNAMIDOACETYL] N METHYLAMINO]BENZYLOXY] 2 METHYLIMIDAZO[1,2 A]PYRIDINE; 3 BROMO 8 [[2,6 DICHLORO 3 [N [4 (N,N DIMETHYLCARBAMOYL)CINNAMAMIDOACETYL] N METHYLAMINO]BENZYL]OXY] 2 METHYLIMIDAZO[1,2 A]PYRIDINE; 8 [[3 (N ACYLGLYCYL N METHYLAMINO) 2,6 DICHLOROBENZYL]OXY] 3 HALO 2 METHYLIMIDAZO[1,2 A]PYRIDINE; 8 [[3 [N [3 (6 ACETAMIDOPYRIDIN 3 YL)ACRYLOYLGLYCYL] N METHYLAMINO] 2,6 DICHLOROBENZYL]OXY] 2 METHYLQUINOLINE; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; TRITIUM; UNCLASSIFIED DRUG;

EID: 15644367578     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980300f     Document Type: Article
Times cited : (102)

References (32)
  • 1
    • 0018995127 scopus 로고
    • Pharmacology of Bradykinin and Related Kinins
    • Regoli, D.; Barabé, J. Pharmacology of Bradykinin and Related Kinins. Pharmacol. Rev. 1980, 32, 1-46.
    • (1980) Pharmacol. Rev. , vol.32 , pp. 1-46
    • Regoli, D.1    Barabé, J.2
  • 2
    • 0020698191 scopus 로고
    • Pharmacology of Kinins: Their Relevance to Tissue Injury and Inflammation
    • Marceau, F.; Lussier, A.; Regoli, D.; Giroud, J. P. Pharmacology of Kinins: Their Relevance to Tissue Injury and Inflammation. Gen. Pharmacol. 1983, 14, 209-229.
    • (1983) Gen. Pharmacol. , vol.14 , pp. 209-229
    • Marceau, F.1    Lussier, A.2    Regoli, D.3    Giroud, J.P.4
  • 3
    • 0024152111 scopus 로고
    • Kinin Formation: Mechanisms and Role in Inflammatory Disorders
    • Proud, D.; Kaplan, A. P. Kinin Formation: Mechanisms and Role in Inflammatory Disorders. Annu. Rev. Immunol. 1988, 6, 49-83.
    • (1988) Annu. Rev. Immunol. , vol.6 , pp. 49-83
    • Proud, D.1    Kaplan, A.P.2
  • 4
    • 0027532297 scopus 로고
    • Bradykinin and Inflammatory Pain
    • Dray, A.; Perkins, M. Bradykinin and Inflammatory Pain. Trends Neurosci. 1993, 16, 99-104.
    • (1993) Trends Neurosci. , vol.16 , pp. 99-104
    • Dray, A.1    Perkins, M.2
  • 5
    • 0023760103 scopus 로고
    • Inflammation and Mediators
    • Greaves, M. W. Inflammation and Mediators. Br. J. Dermatol. 1988, 119, 419-426.
    • (1988) Br. J. Dermatol. , vol.119 , pp. 419-426
    • Greaves, M.W.1
  • 6
    • 0026556434 scopus 로고
    • Bioregulation of Kinins: Kallikreins, Kininogens and Kininases
    • Bhoola, K. D.; Figueroa, C. D.; Worthy, K. Bioregulation of Kinins: Kallikreins, Kininogens and Kininases. Pharmacol. Rev. 1992, 44, 1-80.
    • (1992) Pharmacol. Rev. , vol.44 , pp. 1-80
    • Bhoola, K.D.1    Figueroa, C.D.2    Worthy, K.3
  • 7
  • 12
    • 0021877149 scopus 로고
    • Competitive Antagonists of Bradykinin
    • Vavrek, R. J.; Stewart, J. M. Competitive Antagonists of Bradykinin. Peptides 1985, 6, 161-164.
    • (1985) Peptides , vol.6 , pp. 161-164
    • Vavrek, R.J.1    Stewart, J.M.2
  • 17
    • 0000761899 scopus 로고
    • Structure-Based Drug Design: Progress Toward the Discovery of the Elusive Bradykinin Receptor Antagonists
    • Kyle, D. J. Structure-Based Drug Design: Progress Toward The Discovery of The Elusive Bradykinin Receptor Antagonists. Curr. Pharm. Des. 1995, 1, 233-254.
    • (1995) Curr. Pharm. Des. , vol.1 , pp. 233-254
    • Kyle, D.J.1
  • 27
    • 0031002974 scopus 로고    scopus 로고
    • 2 Antago nist, on Kinin-Induced Hypotension, Visceral and Peripheral Oedema Formation and Bronchoconstriction
    • 2 Antagonist, on Kinin-Induced Hypotension, Visceral and Peripheral Oedema Formation and Bronchoconstriction. Br. J. Pharmacol. 1997, 120, 933-939.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 933-939
    • Griesbacher, T.1    Legat, F.J.2
  • 28
    • 0030913686 scopus 로고    scopus 로고
    • 2 Antagonist FR173657 on Kinin-induced Smooth Muscle Contraction and Relaxation, Vasoconstriction and Prostaglandin Release
    • 2 Antagonist FR173657 on Kinin-induced Smooth Muscle Contraction and Relaxation, Vasoconstriction and Prostaglandin Release. Br. J. Pharmacol. 1997, 121, 469-476.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 469-476
    • Griesbacher, T.1    Sametz, W.2    Legat, F.J.3    Diethart, S.4    Hammer, S.5    Juan, H.6
  • 32
    • 0026662844 scopus 로고
    • A 5-Lipoxygenase Inhibitor, FR110302, Suppresses Airway Hyperresponsiveness and Lung Eosinophilia Induced by Sephadex Particles in Rats
    • Asano, M.; Inamura, N.; Nakahara, K.; Nagayoshi, A.; Isono, T.; Hamada, K.; Oku, T.; Notsu, Y.; Kohsaka, M.; Ono, T. A 5-Lipoxygenase Inhibitor, FR110302, Suppresses Airway Hyperresponsiveness and Lung Eosinophilia Induced by Sephadex Particles in Rats. Agents Actions 1992, 36, 215-221.
    • (1992) Agents Actions , vol.36 , pp. 215-221
    • Asano, M.1    Inamura, N.2    Nakahara, K.3    Nagayoshi, A.4    Isono, T.5    Hamada, K.6    Oku, T.7    Notsu, Y.8    Kohsaka, M.9    Ono, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.