Human cytomegalovirus, MHC class I and inhibitory signalling receptors: More questions than answers

Immunological Reviews

Volumn 168, Issue , 1999, Pages 177-185

  Cosman, David ^a   Fanger, Neil ^a   Borges, Luis ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RECEPTOR;

B LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CYTOMEGALOVIRUS; MONOCYTE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS CELL INTERACTION; VIRUS IMMUNITY;

ANIMALS; ANTIGENS, CD; CAPSID; CAPSID PROTEINS; CYTOMEGALOVIRUS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION;

EID: 0033041240     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1999.tb01292.x     Document Type: Review

References (71)

1. 1. Wattre P, Dewilde A, Lobert PE. Current status of human cytomegalovirus disease. Rev Med Interne 1995;16:354-367.
2. 2. Rook AH. Interactions of cytomegalovirus with the human immune system. Rev Infect Dis 1988;10 (Suppl 3):S460-467.
3. 3. Spriggs MK. One step ahead of the game: viral immunomodulatory molecules. Annu Rev Immunol 1996;14:101-130.
4. 4. Chee MS, et al. Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr Top Microbiol Immunol 1990;154:125-169.
5. 5. Damon I, Murphy PM, Moss B. Broad spectrum chemokine antagonistic activity of a human poxvirus chemokine homolog. Proc Natl Acad Sci USA 1998;95:6403-6407.
6. 6. Comeau MR, et al. A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR. Immunity 1998;8:473-482.
7. 7. Beersma MF, Bijlmakers MJ, Ploegh HL. Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains. J Immunol 1993:151:4455-4464.
8. 8. Ahn KS, Angulo A, Ghazal P, Peterson PA, Yang Y, Früh K. Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc Natl Acad Sci USA 1996;93:10990-10995.
9. 9. Jones TR, Hanson LK, Sun L, Slater JS, Stenberg RM, Campbell AE. Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J Virol 1995;69:4830-4841.
10. 10. Jones TR, Wiertz EJ, Sun L, Fish KN, Nelson JA, Ploegh HL. Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc Natl Acad Sci USA 1996;93:11327-11333.
11. 11. Wiertz EJ, Jones TR, Sun L, Bogyo M, Geuze HJ, Ploegh HL. The human cytomegalovirus US1 1 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 1996;84:769-779.
12. 12. Beck S, Barrell BG. Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens. Nature 1988;331:269-272.
13. 13. Browne H, Smith G, Beck S, Minson T. A complex between the MHC class I homologue encoded by human cytomegalovirus and β2 microglobulin. Nature 1990;347:770-772.
14. 14. Fahnestock ML, Johnson JL, Feldman RM, Neveu JM, Lane WS, Bjorkman PJ. The MHC class I homolog encoded by human cytomegalovirus binds endogenous peptides. Immunity 1995;3:583-590.
15. 15. Browne H, Churcher M, Minson T. Construction and characterization of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deleted. J Virol 1992;66:6784-6787.
16. 16. Biron CA, Byron KS, Sullivan JL. Severe herpesvirus infections in an adolescent without natural killer cells. N Engl J Med 1989;320:1731-1735.
17. 17. Ljunggren HG, Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990;11:237-244.
18. 18. Moretta A, et al. Receptors for HLA class-I molecules in human natural killer cells. Annu Rev Immunol 1996;14:619-648.
19. 19. Moretta A, et al. Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunol Rev 1997;155:105-117.
20. 20. Long EO, et al. Killer cell inhibitory receptors: diversity, specificity, and function. Immunol Rev 1997;155:135-144.
21. 21. Colonna M. Specificity and function of immunoglobulin superfamily NK cell inhibitory and stimulatory receptors. Immunol Rev 1997;155:127-133.
22. 22. Lanier LL, Corliss B, Phillips JH. Arousal and inhibition of human NK cells. Immunol Rev 1997;155:145-154.
23. 23. Cosman D, et al. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 1997;7:273-282.
24. 24. Vivier E, Daeron M. Immunoreceptor tyrosine-based inhibition motifs. Immunol Today 1997;18:286-291.
25. 25. Unkeless JC, Jin J. Inhibitory receptors, ITIM sequences and phosphatases. Curr Opin Immunol 1997;9:338-343.
26. 26. Borges L, Hsu ML, Fanger N, Kubin M, Cosman D. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J Immunol 1997;159:5192-5196.
27. 27. Samaridis J, Colonna M. Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways. Eur J Immunol 1997;27:660-665.
28. 28. Colonna M, et al. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 1997;186:1809-1818.
29. 29. Cella M, et al. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med 1997;185:1743-1751.
30. 30. Wagtmann N, Rojo S, Eichler E, Mohrenweiser H, Long EO. A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors. Curr Biol 1997;7:615-618.
31. 31. Arm JP, Nwankwo C, Austen KF. Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor. J Immunol 1997;159:2342-2349.
32. 32. Lanier LL, Corliss BC, Wu J, Leong C, Phillips JH. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 1998;391:703-707.
33. 33. Cambier JC. Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM). J Immunol 1995;155:3281-3285.
34. 34. Kubagawa H, Burrows PD, Cooper MD. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc Natl Acad Sci USA 1997;94:5261-5266.
35. 35. Hayami K, et al. Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors. J Biol Chem 1997;272:7320-7327.
36. 36. Maliszewski CR, March CJ, Schoenborn MA, Gimpel S, Shen L. Expression cloning of a human Fc receptor for IgA. J Exp Med 1990;172:1665-1672.
37. 37. Zhang G, Young JR, Tregaskes CA, Sopp P, Howard CJ. Identification of a novel class of mammalian Fc γ receptor. J Immunol 1995;155:1534-1541.
38. 38. Castells MC, Wu X, Arm JP, Austen KF. Katz HR. Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49. J Biol Chem 1994;269:8393-8401.
39. 39. Rojo S, Burshtyn DN, Long EO, Wagtmann N. Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells. J Immunol 1997;158:9-12.
40. 40. Wang LL, Mehta IK, LeBlanc PA, Yokoyama WM. Mouse natural killer cells express gp49B1, a structural homologue of human killer inhibitory receptors. J Immunol 1997;158:13-17.
41. 41. Meyaard L, et al. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 1997;7:283-290.
42. 42. Pessino A, et al. Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J Exp Med 1998;188:953-960.
43. 43. Torkar M, Norgate Z, Colonna M, Trowsdale J, Wilson MJ. Isotypic variation of immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex. Eur J Immunol 1998;28:3959-3967.
44. 44. De Wit TP, Morton HC, Capel PJ, van de Winkel JG. Structure of the gene for the human myeloid IgA Fc receptor (CD89). J Immunol 1995;155:1203-1209.
45. 45. Suto Y, et al. Chromosomal localization of the human natural killer cell class I receptor family genes to 19q13.4 by fluorescence in situ hybridization. Genomics 1996;35:270-272.
46. 46. Fanger NA, Cosman D, Peterson L, Braddy SC, Maliszewski CR, Borges L. The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes. Eur J Immunol 1998;28:3423-3434.
47. 47. Shimizu Y, DeMars R. Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line. J Immunol 1989;142:3320-3328.
48. 48. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL. Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence, of the target cell type. J Exp Med 1993;178:1321-1336.
49. 49. Colonna M, et al. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol 1998;160:3096-3100.
50. 50. Scharenberg AM, Kinet JP. The emerging field of receptor-mediated inhibitory signaling: SHP or SHIP? Cell 1996;87:961-964.
51. 51. Yamashita Y, Ono M, Takai T. Inhibitory and stimulatory functions of paired Ig-like receptor (PIR) family in RBL-2H3 cells. J Immunol 1998;161:4042-4047.
52. 52. Maeda A, Kurosaki M, Ono M, Takai T, Kurosaki T. Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal. J Exp Med 1998;187:1355-1360.
53. 53. Katz HR, Austen KF. A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family. J Immunol 1997;158:5065-5070.
54. + natural killer cell clones. Int Immunol 1999;11:29-35.
55. 55. Reyburn HT, Mandelboim O, Vales-Gomez M, Davis DM, Pazmany L, Strominger JL. The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells. Nature 1997;386:514-517.
56. 56. Leong CC, et al. Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: the role of endogenous class I major histocompatibility complex and a viral class I homolog. J Exp Med 1998;187:1681-1687.
57. 57. Braud VM, et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998;391:795-799.
58. 58. Lee N, et al. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proc Natl Acad Sci USA 1998;95;5199-5204.
59. 59. Fletcher JM, Prentice HG, Grundy JE. Natural killer cell lysis of cytomegalovirus (CMV)-infected cells correlates with virally induced changes in cell surface lymphocyte function-associated antigen-3 (LFA-3) expression and not with the CMV-induced down regulation of cell surface class I HLA. J Immunol 1998;161:2365-2374.
60. 60. Biron CA. Activation and function of natural killer cell responses during viral infections. Curr Opin Immunol 1997;9:24-34.
61. 61. Farrell HE, et al. Inhibition of natural killer cells by a cytomogalovirus MHC class I homologue in vivo. Nature 1997;386:510-514.
62. 62. Chapman TL, Bjorkman PJ. Characterization of a murine cytomegalovirus class I major histocompatibility complex (MHC) homolog: comparison to MHC molecules and to the human cytomegalovirus MHC homolog. J Virol 1998;72:460-466.
63. 63. Trinchieri G. Natural killer cells wear different hats: effector cells of innate resistance and regulatory cells of adaptive immunity and of hematopoiesis. Semin Immunol 1995;7:83-88.
64. 64. Trinchieri G. Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL 12, IFN γ). Curr Opin Immunol 1997;9:17-23.
65. 65. Atedzoe BN, Ahmad A, Menezes J. Enhancement of natural killer cell cytotoxicity by the human herpesvirus-7 via IL-15 induction. J Immunol 1997;159:4966-4972.
66. 66. Okamura H, Kashiwamura S, Tsutsui H, Yoshimoto T, Nakanishi K. Regulation of interferon γ production hy IL-12 and IL-18. Curr Opin Immunol 1998;10:259-264.
67. 67. Michelson S. Interaction of human cytomegalovirus with monocytes/macrophages: a love-hate relationship. Pathol Biol (Paris) 1997;45:146-158.
68. 68. Zhuravskaya T, Maciejewski JP, Netski DM, Bruening E, Mackintosh FR, Stjeor S. Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency. Blood 1997;90:2482-2491.
69. 69. Hahn G, Jores R. Mocarski ES. Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells. Proc Natl Acad Sci USA 1998;95:3937-3942.
70. 70. Poggi A, Tomasello E, Ferrero E, Zocchi MR, Moretta L. p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony stimulating factor. Eur J Immunol 1998;28:2086-2091.
71. 71. Kharitonenkov A, Chen ZJ, Sures I, Wang HY, Schilling J, Ullrich A. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature 1997;386;181-186.