Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: The role of endogenous class I major histocompatibility complex and a viral class I homolog

Journal of Experimental Medicine

Volumn 187, Issue 10, 1998, Pages 1681-1687

  Leong, Clement C ^a   Chapman, Tara L ^b   Bjorkman, Pamela J ^b   Formankova, Danuska ^c   Mocarski, Edward S ^c   Phillips, Joseph H ^a   Lanier, Lewis L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Class I major histocompatibility complex; Cytomegalovirus; Cytotoxicity; Natural killer cell; UL18

Indexed keywords

CD94 ANTIGEN; CELL ADHESION MOLECULE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ARTICLE; CELL KILLING; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; CYTOTOXICITY; DOWN REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NATURAL KILLER CELL; PRIORITY JOURNAL;

ANTIGENS, VIRAL; CELL LINE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KILLER CELLS, NATURAL;

EID: 0032543206     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.10.1681     Document Type: Article

References (32)

1. Ho, M. 1982. Epidemiology of cytomegalovirus in man. In Cytomegalovirus, Biology and Infection: Current Topics in Infectious Disease. W.B. Greenough III and T.C. Merigan, editors. Plenum Medical Book Co., New York. 77-104.
2. Quinnan, G.V., N. Kirmani, A.H. Rook, J.F. Manishewitz, L. Jackson, G. Moreschi, G.W. Santos, R. Saral, and W.H. Burns. 1982. Cytotoxic T cells in cytomegalovirus infection. N. Engl. J. Med. 307:6-13.
3. Riddell, S.R., K.S. Watanabe, J.M. Goodrich, C.R. Li, M.E. Agha, and P.D. Greenberg. 1992. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science. 257:238-241.
4. Biron, C.A., K.S. Byron, and J.L. Sullivan. 1989. Severe herpesvirus infections in an adolescent without natural killer cells. N. Engl. J. Med. 320:1731-1735.
5. Bukowski, J., J. Warner, G. Dennert, and R. Welsh. 1985. Adoptive transfer studies demonstrating the anti-viral effect of natural killer cells in vivo. J. Exp. Med. 161:40-52.
6. Scalzo, A.A., N.A. Fitzgerald, C. Wallace, A.E. Gibbons, Y.C. Smart, R.C. Burton, and G.R. Shellam. 1992. The effect of the CMV-1 resistance gene, which is linked to the natural killer cell gene complex, is mediated by natural killers. J. Immunol. 149:581-589.
7. Brown, M.G., A.A. Scalzo, K. Matsumoto, and W.M. Yokoyama. 1997. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155:53-65.
8. Lanier, L.L., and J.H. Phillips. 1995. NK cell recognition of major histocompatibility complex class I molecules. Semin. Immunol. 7:75-82.
9. Beck, S., and B.G. Barrell. 1988. Human cytomegalovirus encodes a glycoprotein homologous to MHC class I antigens. Nature. 331:269-272.
10. Farrel, H., H. Vally, D. Lynch, P. Fleming, G. Shellam, A. Scalzo, and N. Davis-Poynter. 1997. Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo. Nature. 386:446-447.
11. Reyburn, H.T., O. Mandelbolm, M. Vales-Gomez, D. Davis, L. Pazmany, and J. Strominger. 1997. The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells, Nature. 386:514-517.
12. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M.-L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity. 7:273-282.
13. Borges, L., M.-L. Hsu, N. Fanger, M. Kubin, and D. Cosman. 1997. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159:5192-5196.
14. Litwin, V., J. Gumperz, P. Parham, J.H. Phillips, and L.L. Lanier. 1993. Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type. J. Exp. Med. 178:1321-1336.
15. Yssel, H., J.D. Vries, M. Koken, W. van Blittersijk, and H. Spits. 1984. Serum-free medium for the generation and the propagation of functional human cytotoxic and helper T cell clones. J. Immunol. Methods. 72:219-227.
16. Mocarski, E.S., M. Bonyhadi, S. Salimi, J.M. McCune, and H. Kaneshima. 1993. Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication. Proc. Natl. Acad. Sci. USA. 90:104-108.
17. Lanier, L.L., and D.J. Recktenwald. 1991. Multicolor immunofluorescence and flow cytometry. Methods: A Companion to Methods in Enzymology 2:192-199.
18. Phillips, J., J. Gumperz, P. Parham, and L. Lanier. 1995. Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science. 268:403-405.
19. Phillips, J., C. Chang, J. Mattson, J. Gumperz, P. Parham, and L.L. Lanier. 1996. Human C-type lectins and MHC class I recognition: evidence for involvement of CD94-associated proteins (CD94AP) in recognition of HLA-A, -B, and -C. Immunity. 5:163-172.
20. Browne, H., M. Churcher, and T. Minson. 1992. Construction and characterisation of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deleted. J. Virol. 66:6784-6787.
21. Beersma, M.F., M.J. Bijlmakers, and H.L. Ploegh. 1993. Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I heavy chains. J. Immunol. 151:4455-4464.
22. Karre, K., H.G. Ljunggren, G. Plontek, and R. Kiessling. 1986. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy. Nature. 319:675-678.
23. Browne, H., G. Smith, S. Beck, and T. Minson. 1990. A complex between the MHC class I homologue encoded by human cytomegalovirus and β2-microglobulin. Nature. 347:770-772.
24. Fahnestock, M.L., J.L. Johnson, R.M.R. Feldman, J.M. Neveu, W.S. Lane, and P.J. Bjorkman. 1995. The MHC class I homolog encoded by human cytomegalovirus binds endogenous peptides. Immunity. 3:583-590.
25. Malnati, M.S., M. Peruzzi, K.C. Parker, W.E. Biddison, E. Ciccone, A. Moretta, and E.O. Long. 1995. Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science. 267:1016-1018.
26. Ciccone, E., D. Pende, L. Nanni, C. Di Donato, O. Viale, A. Beretta, M. Vitale, S. Sivori, A. Moretta, and L. Moretta. 1995. General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect. Int. Immunol. 7:393-400.
27. Braud, V., E.Y. Jones, and A. McMichael. 1997. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with anchor residues at positions 2 and 9. Eur. J. Immunol. 27:1164-1169.
28. Tzeng, C.-M., E.J. Adams, J.E. Gumperz, L. Percival, and L.D. Barber. 1996. Peptides bound endogenously by HLA-Cw*0304 expressed in LCL 721.221 cells include a peptide derived from HLA-E. Tissue Antigens. 48:325-328.
29. Braud, V.M., D.S.J. Allan, C.A. O'Callaghan, K. Soderstrom, A. D'Andrea, G.S. Ogg, S. Lazetic, N.T. Young, J.I. Bell, J.H. Phillips, et al. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B, and C. Nature. 391:795-799.
30. Samaridis, J., and M. Colonna. 1997. Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways. Eur. J. Immunol. 27:660-665.
31. Colonna, M., F. Navarro, T. Bellon, M. Llano, P. Garcia, J. Samaridis, L. Angman, M. Cella, and M. Lopez-Botet. 1997. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186:1809-1818.
32. Soderberg-Naucler, C., K.N. Fish, and J.A. Nelson. 1997. Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors. Cell. 91:119-126.