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Volumn 11, Issue 6, 1999, Pages 899-906

Expansion of neonatal tolerance to self in adult life: I. The role of a bacterial adjuvant in tolerance spread

Author keywords

Complete freund's adjuvant; Determinant spreading; Experimental autoimmune encephalomyelitis; Mycobacterium tuberculosis; Myelin basic protein; Neonatal tolerance

Indexed keywords

EPITOPE; FREUND ADJUVANT; INTERLEUKIN 4; NEUTRALIZING ANTIBODY;

EID: 0033037807     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.6.899     Document Type: Article
Times cited : (9)

References (56)
  • 2
    • 0026589793 scopus 로고
    • Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. I. T cell receptor peptide regulation of T cell clones expressing cross-reactive V beta genes
    • Offner, H., Vainiene, M., Gold, D. P., Celnik, B., Wang, R., Hashim, G. A. and Vandenbark, A. A. 1992. Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. I. T cell receptor peptide regulation of T cell clones expressing cross-reactive V beta genes. J. Immunol. 148:1706.
    • (1992) J. Immunol. , vol.148 , pp. 1706
    • Offner, H.1    Vainiene, M.2    Gold, D.P.3    Celnik, B.4    Wang, R.5    Hashim, G.A.6    Vandenbark, A.A.7
  • 3
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann, P. V., Forsthuber, T., Miller, A. and Sercarz, E. E. 1992. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358:155.
    • (1992) Nature , vol.358 , pp. 155
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 4
    • 0027430682 scopus 로고
    • Shifts in the epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis
    • Mor, F. and Cohen, I. R. 1993. Shifts in the epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis. J. Clin. Invest. 92:2199.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2199
    • Mor, F.1    Cohen, I.R.2
  • 5
    • 0028360612 scopus 로고
    • Definition of encephalitogenic and immunodominant epitopes of guinea pig myelin basic protein (Gp-BP) in Lewis rats tolerized neonatally with Gp-BP or Gp-BP peptides
    • Vandenbark, A. A., Vainiene, M., Celnik, B., Hashim, G. A., Buenafe, A. and Offner, H. 1994. Definition of encephalitogenic and immunodominant epitopes of guinea pig myelin basic protein (Gp-BP) in Lewis rats tolerized neonatally with Gp-BP or Gp-BP peptides. J Immunol. 153:852.
    • (1994) J Immunol. , vol.153 , pp. 852
    • Vandenbark, A.A.1    Vainiene, M.2    Celnik, B.3    Hashim, G.A.4    Buenafe, A.5    Offner, H.6
  • 6
    • 0024592929 scopus 로고
    • Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein
    • Clayton, J. P., Gammon, G. M., Ando, D. G., Kono, D. H., Hood, L. and Sercarz, E. E. 1989. Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein. J. Exp. Med. 169:1681.
    • (1989) J. Exp. Med. , vol.169 , pp. 1681
    • Clayton, J.P.1    Gammon, G.M.2    Ando, D.G.3    Kono, D.H.4    Hood, L.5    Sercarz, E.E.6
  • 7
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis
    • McRae, B. L., Vanderlugt, C. L., Dal Canto, M. C. and Miller, S. D. 1995. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis. J. Exp. Med. 182:75.
    • (1995) J. Exp. Med. , vol.182 , pp. 75
    • McRae, B.L.1    Vanderlugt, C.L.2    Dal Canto, M.C.3    Miller, S.D.4
  • 8
    • 0025309472 scopus 로고
    • Clonal deletion versus clonal anergy: The role of the thymus in inducing self tolerance
    • Ramsdell, F. and Fowlkes, B. J. 1990. Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance. Science 248:1342.
    • (1990) Science , vol.248 , pp. 1342
    • Ramsdell, F.1    Fowlkes, B.J.2
  • 9
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elemination in the thymus
    • Kappler, J., Roehm, N. and Marrack, P. 1987. T cell tolerance by clonal elemination in the thymus. Cell 49:273.
    • (1987) Cell , vol.49 , pp. 273
    • Kappler, J.1    Roehm, N.2    Marrack, P.3
  • 10
    • 0022445860 scopus 로고
    • Induction of tolerance to one determinant on a synthetic peptide does not affect the response to a second linked determinant. Implications for the mechanism of neonatal tolerance induction
    • Gammon, G. M., Oki, A., Shastri, N. and Sercarz, E. E. 1986. Induction of tolerance to one determinant on a synthetic peptide does not affect the response to a second linked determinant. Implications for the mechanism of neonatal tolerance induction J. Exp. Med. 164:667.
    • (1986) J. Exp. Med. , vol.164 , pp. 667
    • Gammon, G.M.1    Oki, A.2    Shastri, N.3    Sercarz, E.E.4
  • 11
    • 0028361047 scopus 로고
    • Role of cytokines in determining T-lymphocyte function
    • O'Garra, A. and Murphy, K. 1994. Role of cytokines in determining T-lymphocyte function. Curr. Opin. Immunol. 6:458.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 458
    • O'Garra, A.1    Murphy, K.2
  • 12
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., Murphy, K. M. and Sher, A. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 15
    • 0027491655 scopus 로고
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming. Proc. Natl Acad. Sci. USA 90:10188.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 10188
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 18
    • 0024353079 scopus 로고
    • h2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • h2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 9:145.
    • (1989) Annu. Rev. Immunol. , vol.9 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 20
    • 0031572577 scopus 로고    scopus 로고
    • IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent
    • Huang, H., Hu-Li, J., Chen, H., Ben-Sasson, S. Z. and Paul, W. E. 1997. IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent. J. Immunol. 159:3731.
    • (1997) J. Immunol. , vol.159 , pp. 3731
    • Huang, H.1    Hu-Li, J.2    Chen, H.3    Ben-Sasson, S.Z.4    Paul, W.E.5
  • 22
    • 0030002897 scopus 로고    scopus 로고
    • Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: Implications for antibody vs. T cell-mediated autoimmunity
    • Singh, R. R., Hahn, B. H. and Sercarz, E. E. 1996. Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity [see comments]. J. Exp. Med. 183:1613.
    • (1996) J. Exp. Med. , vol.183 , pp. 1613
    • Singh, R.R.1    Hahn, B.H.2    Sercarz, E.E.3
  • 24
    • 0030012251 scopus 로고    scopus 로고
    • Induction of protective CTL responses in newborn mice by a murine retrovirus
    • Sarzotti, M., Robbins, D. S. and Hoffman, P. M. 1996. Induction of protective CTL responses in newborn mice by a murine retrovirus [see comments]. Science 271:1726.
    • (1996) Science , vol.271 , pp. 1726
    • Sarzotti, M.1    Robbins, D.S.2    Hoffman, P.M.3
  • 25
    • 0029991928 scopus 로고    scopus 로고
    • Neonatal tolerance revisited: Turning on newborn T cells with dendritic cells
    • Ridge, J. P., Fuchs, E. J. and Matzinger, P. 1996. Neonatal tolerance revisited: turning on newborn T cells with dendritic cells [see comments]. Science 271:1723.
    • (1996) Science , vol.271 , pp. 1723
    • Ridge, J.P.1    Fuchs, E.J.2    Matzinger, P.3
  • 26
    • 0019465142 scopus 로고
    • The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
    • Ben-Nun, A., Wekerle, H. and Cohen, I. R. 1981. The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur. J. Immunol. 11:195.
    • (1981) Eur. J. Immunol. , vol.11 , pp. 195
    • Ben-Nun, A.1    Wekerle, H.2    Cohen, I.R.3
  • 27
    • 0027196705 scopus 로고
    • Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis
    • Karin, N., Szafer, F., Mitchell, D., Gold, D. P. and Steinman, L. 1993. Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis. J. Immunol. 150:4116.
    • (1993) J. Immunol. , vol.150 , pp. 4116
    • Karin, N.1    Szafer, F.2    Mitchell, D.3    Gold, D.P.4    Steinman, L.5
  • 28
    • 0028148199 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis by as soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of IFN-γ and TNF-α production
    • Karin, N., Mitchell, J. D., Brocke, S., Ling, N. and Steinman, L. 1994. Reversal of experimental autoimmune encephalomyelitis by as soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of IFN-γ and TNF-α production. J. Exp. Med. 180:2227.
    • (1994) J. Exp. Med. , vol.180 , pp. 2227
    • Karin, N.1    Mitchell, J.D.2    Brocke, S.3    Ling, N.4    Steinman, L.5
  • 29
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • Yednock, T. A., Cannon, C., Fritz, L. C., Sanchez, M. F., Steinman, L. and Karin, N. 1992. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 356:63.
    • (1992) Nature , vol.356 , pp. 63
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez, M.F.4    Steinman, L.5    Karin, N.6
  • 31
    • 0029091018 scopus 로고
    • Pathogenicity of T cells responsive to diverse cryptic epitopes of myelin basic protein in the Lewis rat
    • Mor, F. and Cohen, I. R. 1995. Pathogenicity of T cells responsive to diverse cryptic epitopes of myelin basic protein in the Lewis rat. J. Immunol. 155:3693.
    • (1995) J. Immunol. , vol.155 , pp. 3693
    • Mor, F.1    Cohen, I.R.2
  • 32
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E. C. and Picker, L. J. 1996. Lymphocyte homing and homeostasis. Science 272:60.
    • (1996) Science , vol.272 , pp. 60
    • Butcher, E.C.1    Picker, L.J.2
  • 34
    • 0026791975 scopus 로고
    • The immune system evolved to discriminate infectious nonself from noninfectious self
    • Janeway, C. A., Jr. 1992. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol. Today. 13:11.
    • (1992) Immunol. Today. , vol.13 , pp. 11
    • Janeway C.A., Jr.1
  • 35
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger, P. 1994. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12:991.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991
    • Matzinger, P.1
  • 36
    • 0030818169 scopus 로고    scopus 로고
    • Viral damage and the breakdown of self-tolerance
    • Steinman, L. and Conlon, P. 1997. Viral damage and the breakdown of self-tolerance. Nat. Med. 3:1085.
    • (1997) Nat. Med. , vol.3 , pp. 1085
    • Steinman, L.1    Conlon, P.2
  • 37
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases
    • Miller, S. D. and Karpus, W. J. 1994. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol. Today 15:356.
    • (1994) Immunol. Today , vol.15 , pp. 356
    • Miller, S.D.1    Karpus, W.J.2
  • 39
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig, K. W. and Strominger, J. L. 1995. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 80:695.
    • (1995) Cell , vol.80 , pp. 695
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 42
    • 0028089802 scopus 로고
    • Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats
    • Cash, E., Minty, A., Ferrara, P., Caput, D., Fradelizi, D. and Rott, O. 1994. Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. J. Immunol. 153:4258.
    • (1994) J. Immunol. , vol.153 , pp. 4258
    • Cash, E.1    Minty, A.2    Ferrara, P.3    Caput, D.4    Fradelizi, D.5    Rott, O.6
  • 44
    • 0028966091 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
    • Leonard, J. P., Waldburger, K. E. and Goldman, S. J. 1995. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12. J. Exp. Med. 181:381.
    • (1995) J. Exp. Med. , vol.181 , pp. 381
    • Leonard, J.P.1    Waldburger, K.E.2    Goldman, S.J.3
  • 47
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • Ando, D. G., Clayton, J., Kono, D., Urban, J. L. and Sercarz, E. E. 1989. Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell. Immunol. 124:132.
    • (1989) Cell. Immunol. , vol.124 , pp. 132
    • Ando, D.G.1    Clayton, J.2    Kono, D.3    Urban, J.L.4    Sercarz, E.E.5
  • 48
    • 0029030964 scopus 로고
    • T helper subsets in insulin dependent diabetes
    • Katz, J. D., Benoist, C. and Mathis, D. 1995. T helper subsets in insulin dependent diabetes. Science 268:1185.
    • (1995) Science , vol.268 , pp. 1185
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 52
    • 0028245010 scopus 로고
    • Interleukin-10 prevents experimental allergic encephalomyelitis in rats
    • Rott, O., Fleischer, B. and Cash, E. 1994. Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur. J. Immunol. 24:1434.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1434
    • Rott, O.1    Fleischer, B.2    Cash, E.3
  • 55
    • 0031571784 scopus 로고    scopus 로고
    • Tolerance to a dominant T cell epitope in the acetylcholine receptor molecule induces epitope spread and suppresses murine myasthenia gravis
    • Wu, B., Deng, C., Goluszko, E. and Christadoss, P. 1997. Tolerance to a dominant T cell epitope in the acetylcholine receptor molecule induces epitope spread and suppresses murine myasthenia gravis. J. Immunol. 159:3016.
    • (1997) J. Immunol. , vol.159 , pp. 3016
    • Wu, B.1    Deng, C.2    Goluszko, E.3    Christadoss, P.4


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