F 11356, a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT(1B/1D) receptors in models relevant to migraine

Journal of Pharmacology and Experimental Therapeutics

Volumn 290, Issue 1, 1999, Pages 83-95

  John, Gareth W ^a   Pauwels, Petrus J ^a   Perez, Michel ^a   Halazy, Serge ^a   Le Grand, Bruno ^a   Verscheure, Wan ^a   Valentin, Jean Pierre ^a   Palmier, Christiane ^a   Wurch, Thierry ^a   Chopin, Philippe ^a   Marien, Marc ^a   Kleven, Mark S ^a   Koek, Wouter ^a   Assie, Marie Bernadette ^a   Carilla Durand, Elisabeth ^a   Tarayre, Jean Pierre ^a   Colpaert, Francis C ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

[4 [4 [2 (2 AMINOETHYL) 1H INDOL 5 YLOXYL]ACETYL]PIPERAZINYL 1 YL]BENZONITRILE; [4 [4 [2 [3 (2 AMINOETHYL) 1H INDOL 5 YLOXY] ACETYL] PIPERAZIN 1 YL] BENZONITRILE; CYCLIC AMP; FLESINOXAN; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; NARATRIPTAN; RIZATRIPTAN; SEROTONIN; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN DERIVATIVE; SUMATRIPTAN; TRYPTAMINE; UNCLASSIFIED DRUG; ZOLMITRIPTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAROTID ARTERY FLOW; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG TOLERABILITY; MIGRAINE; NONHUMAN; ORAL DRUG ADMINISTRATION; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SEROTONINERGIC SYSTEM;

ANIMALS; CAROTID ARTERIES; CYCLIC AMP; DISEASE MODELS, ANIMAL; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUINEA PIGS; HEART; HEMODYNAMIC PROCESSES; HUMANS; HYPOTHERMIA; MALE; MIGRAINE DISORDERS; MUSCLE, SMOOTH, VASCULAR; NEURONS; NITRILES; PIPERAZINES; RABBITS; RADIOLIGAND ASSAY; RATS; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; RECEPTORS, SEROTONIN; SAPHENOUS VEIN; SWINE; TRIGEMINAL GANGLION; TRYPTAMINES;

EID: 0033006416     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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