Differential expression of sumatriptan-sensitive 5-hydroxytryptamine receptors in human trigeminal ganglia and cerebral blood vessels

Molecular Pharmacology

Volumn 50, Issue 2, 1996, Pages 219-223

  Bouchelet, Isabelle ^a   Cohen, Zvi ^a   Case, Bruce ^b   Séguéla, Philippe ^a   Hamel, Edith ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR SUBTYPE; SEROTONIN 1D RECEPTOR; SEROTONIN RECEPTOR; SUMATRIPTAN;

ARTICLE; BRAIN BLOOD VESSEL; FEMALE; HUMAN; HUMAN TISSUE; MALE; MIGRAINE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESTRICTION MAPPING; TISSUE DISTRIBUTION; TRIGEMINUS GANGLION;

ADULT; BASE SEQUENCE; CEREBRAL ARTERIES; FEMALE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN AGONISTS; SUMATRIPTAN; TRIGEMINAL GANGLION;

EID: 0029813854     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. 1-like receptor in dog isolated saphenous vein. Br. J. Pharmacol. 94:1123-1132 (1988).
2. Doenicke, A., J. Brand, and V. L. Perrin. Possible benefit of GR 43175, a novel 5-HT1-like receptor agonist, for the acute treatment of severe migraine. Lancet 1:1309-1311 (1988).
3. Humphrey, P. P. A., and W. Feniuk. Mode of action of the anti-migraine drug sumatriptan. Trends Pharmacol. Sci. 12:444-446 (1991).
4. Humphrey, P. P. A. 5-Hydroxytryptamine and the pathophysiology of migraine. J. Neurol. 238:S38-S44 (1991).
5. Moskowitz, M. A. Neurogenic versus vascular mechanisms of sumatriptan and ergot alkaloids in migraine. Trends. Pharmacol. Sci. 13:307-311 (1992).
6. Connor, H. E., and D. T. Beattie. 5-HT receptor subtypes and migraine, in Migraine, Pharmacology and Genetics (M. Sandier, M. Ferrari, and S. Harnett, eds.). Chapman and Hall, London, 18-28 (1996).
7. 1D receptors: pharmacology and therapeutic potential. Serotonin 1: 19-29 (1996).
8. 1D receptor genes. Trends Pharmacol. Sci. 13:152-159 (1992).
9. 1Dβ. Proc. Natl. Acad. Sci, USA 89:3630-3634 (1992).
10. 1D binding sites. Br. J. Pharmacol. 103:1421-1428 (1991).
11. 1Dβ receptor subtype in human and bovine cerebral arteries. Mol. Pharmacol. 44:242-246 (1993).
12. 1Dβ" receptors. Eur. J. Pharmacol. 242:75-82 (1993).
13. Buzzi, M. G., M. A. Moskowitz, S. J. Peroutka, and B. Byun. Further characterization of the putative 5-HT receptor which mediates blockade of neurogenic plasma extravasation in rat dura mater. Br. J. Pharmacol. 103:1421-1428 (1991).
14. Lee, W. S., and M. A. Moskowitz. Conformationally restricted sumatriptan analogues, CP-122,288 and CP-122,638 exhibit enhanced potency against neurogenic inflammation in dura mater. Brain Res. 626:303-305 (1993).
15. 1D] neurogenic plasma extravasation within guinea pig dura mater. Cephalalgia 15(Suppl. 14):117 (1995).
16. Beattie, D. T., and H. E. Connor. The pre- and postjunctional activity of CP-122,288, a conformationally restricted analogue of sumatriptan. Eur. J. Pharmacol. 276:271-276 (1995).
17. 1Dα serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug development. Proc. Natl. Acad. Sci. USA 91:3666-3669 (1994).
18. 1 receptor subtype coupled to the inhibition of adenylate cyclase. Proc. Natl. Acad. Sci. USA 90:408-412 (1993).
19. Bouchelet, I., Z. Cohen, B. Case, P. Séguéla, and E. Hamel. Expression of sumatriptan-sensitive serotonin receptors mRNA in human neuronal and vascular tissues. Soc. Neurosci. Abst. 21(Part 3):1853 (1995).
20. Chomczynski, P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15:532-535 (1993).
21. 1B receptor messenger RNA in neurons of the rat trigeminal ganglia. Eur. J. Pharmacol. 277:357-359 (1992).
22. 1D receptor agonist 311C90, in New Advances in Headache Research (F. C. Rose, ed.). Smith Gordon Ltd., London, 3-4 (1994).
23. 1 receptor agonist, CP-122,288, a selective inhibitor of neurogenic inflammation. Br. J. Pharmacol. 116:2385-2390 (1995).
24. Kaumann, A. J., A. A. Parsons, and A. M. Brown. Human arterial constrictor serotonin receptors. Cardiovasc. Res. 27:2094-2103 (1993).
25. Ullmer, C., K. Schmuck, H. O. Kalkman, and H. Lübbert. Expression of serotonin receptor mRNAs in blood vessels. FEBS Lett. 370:215-221 (1995).
26. 2A mRNA in human brain vessels, vascular cells and astrocytes in culture. Soc. Neurosci. Abst. 21(Part 3):1853 (1995).