Stimulation of 5-HT(1B) receptors causes hypothermia in the guinea pig

European Journal of Pharmacology

Volumn 331, Issue 2-3, 1997, Pages 169-174

  Hagan, Jim J ^a   Slade, Paula D ^a   Gaster, Laramie ^a   Jeffrey, Phillip ^b   Hatcher, Jonathan P ^a   Middlemiss, D N ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b The Frythe   (United Kingdom)

Author keywords

5 HT; 5 HT(1B) receptor; 5 HT(1D) receptor; BRL 15572; Guinea pig; Hypothermia; SB 216641A; SB 224289G; SKF 9910IH

Indexed keywords

3 (2 DIMETHYLAMINOETHYL) 4 CHLORO 5 PROPOXYINDOLE; 3 [4 (3 CHLOROPHENYL) 1 PIPERAZINYL] 1,1 DIPHENYL 2 PROPANOL; RECEPTOR SUBTYPE; SB 216641A; SB 224289G; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; BIPHENYL DERIVATIVE; INDOLE DERIVATIVE; N (3 (2 DIMETHYLAMINO)ETHOXY 4 METHOXYPHENYL) 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) (1,1' BIPHENYL) 4 CARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N-(3-(2-DIMETHYLAMINO)ETHOXY-4-METHOXYPHENYL)-2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)-(1,1'-BIPHENYL)-4-CARBOXAMIDE; OXADIAZOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDONE DERIVATIVE; SB 22489G; SEROTONIN RECEPTOR; SPIRO COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GUINEA PIG; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; THERMOREGULATION; ANIMAL; BODY TEMPERATURE; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BENZAMIDES; BIPHENYL COMPOUNDS; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HYPOTHERMIA; INDOLES; MALE; OXADIAZOLES; PIPERAZINES; PIPERIDONES; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SPIRO COMPOUNDS;

EID: 0030610179     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01055-8     Document Type: Article

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