Abnormalities of CD45 isoform expression in HIV infection

Clinical Immunology and Immunopathology

Volumn 81, Issue 2, 1996, Pages 210-214

  Mahalingam, M ^a,c   Pozniak, A ^a   McManus, T J ^a   Senaldi, G ^b   Vergani, D ^a   Peakman, M ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; PHOSPHOTYROSINE;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MEMORY CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030297291     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0178     Document Type: Article

References (14)

1. 1. Ledbetter, J. A., Tonks, N. K., Fischer, E. H., et al., CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells. Proc. Natl. Acad. Sci. USA 85, 8628-8632, 1988.
2. 2. Mahalingam, M., Peakman, M., Davies, E. T., et al., T cell activation and disease severity in HIV infection. Clin. Exp. Immunol. 93, 337-343, 1993.
3. + memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc. Natl. Acad. Sci. USA 87, 6058-6062, 1990.
4. 4. Giorgi, J. V., and Detels, R., T-cell subset alterations in HIV-infected homosexual men: NIAID Multicenter AIDS Cohort Study. Clin. Immunol. Immunopathol. 52, 10-18, 1989.
5. 5. Vuillier, F., Lapresle, C., and Dighiero, G., Comparative analysis of CD4-4B4 and CD4-2H4 lymphocyte subpopulations in HIV negative homosexual, HIV seropositive and healthy subjects. Clin. Exp. Immunol. 71, 8-12, 1988.
6. 6. Sanders, M. E., Makgoba, M. W., and Sharrow, S. O., Human memory T lymphocytes express increased levels of three adhesion molecules (LFA 3, CD2, LFA 1) and three other molecules (UCHL1, CDw29, Pgp-1) and have enhanced IFN-production. J. Immunol. 140, 1401-1407, 1988.
7. 7. Centers for Disease Control and Prevention, 1993 revised classification system for HIV infection and expanded surveillance case definitions for AIDS among adolescents and adults. MMWR 41, 1-19, 1992.
8. 8. Glenny, J. R. Isolation of tyrosine-phosphorylated proteins and generation of monoclonal antibodies. Methods Enzymol. 201, 92-96, 1991.
9. 9. Klein, N. J., Levin, M., Strobel, S., and Finn, A. Degradation of glycosaminoglycans and fibronectin on endotoxin stimulated endothelium by adherent neutrophils: Relationship to CD11b/ CD18 and L-selectin expression. J. Infect. Dis. 167, 890-898, 1993.
10. 10. Prince, H. E., Jensen, E. R., Three color cytometric analysis of CD8 cell subsets in HIV-1 infection. J. AIDS 4, 1227-1232, 1991.
11. 11. Tonks, N. K., Charbonneau, C. D., Diltz, E. H., et al., Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry 27, 8695-8698, 1988.
12. ++ oscillation. J. Exp. Med. 176, 835-844, 1992.
13. 13. Baur, A., Garber, S., Matija-Pterlin, B., Effects of CD45 on NF-κB: Implications for replication of HIV-1. J. Immunol. 152, 976-983, 1994.
14. + lymphocytes from HIV-infected patients display impaired CD45-associated tyrosine phosphatase activity which is enhanced by antioxidants. Clin. Exp. Immunol. 104, 11-17, 1996.