Plasma concentrations of carotenoids in healthy volunteers after intervention with carotenoid-rich foods

European Journal of Nutrition

Volumn 38, Issue 1, 1999, Pages 35-44

  Muller H ^a   Bub, A ^a   Watzl, B ^a   Rechkemmer, Gerhard ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

carotene; carotene; Antioxidant; Carotenoids; Human; Lutein; Lycopene; Oxidation

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; BETA CAROTENE; CAROTENOID; GAMMA TOCOPHEROL; LYCOPENE; RETINOL; UBIDECARENONE; XANTHOPHYLL;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; BIOAVAILABILITY; CARROT; CONTROLLED STUDY; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OXIDATION; SPINACH; TOMATO; VEGETABLE; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

ADULT; ANTIOXIDANTS; BETA CAROTENE; CAROTENOIDS; CHOLESTEROL; DIET; FRUIT; HUMANS; MALE; REFERENCE VALUES; VEGETABLES;

DAUCUS CAROTA; LYCOPERSICON ESCULENTUM; SPINACIA OLERACEA;

EID: 0032988540     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003940050044     Document Type: Article

References (45)

1. The Alpha-Tocopheral, Beta-Carotene Efficiancy Trial (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330:1029-1035
2. Ames BN, Gold LS, Willett WC (1995) The causes and prevention of cancer. Proc Natl Acad Sci USA 92:5258-5265
3. Ben-Amotz A, Levy Y (1996) Bioavailability of a natural isomer mixture compared with synthetic all-trans beta-carotene in human serum. Am J Clin Nutr 63:729-734
4. Block G, Patterson B, Subar A (1992) Fruit vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Canc 18:1-29
5. Brady WE, Mares-Perlman JA, Bowen P, Stacewicz-Sapuntzakis M (1996) Human serum carotenoid concentrations are related to physiologic and lifestyle factors. J Nutr 126:129-137
6. Britton G (1995) Structure and properties of carotenoids in relation to function. FASEB J 9:1551-1558
7. Britton G, Liaaen-Jensen S, Pfander H (1995) Carotenoids. Birkhäuser, Basel. IB
8. Brown ED, Micozzi MS, Craft NE, Bieri JG, Beecher G, Edwards BK, Rose A, Taylor PR, Smith JC (1989) Plasma carotenoids in normal men after a single ingestion of vegetables or purified beta-carotene. Am J Clin Nutr 49:1258-1265
9. Carughi A, Hooper FG (1994) Plasma carotenoid concentrations before and after supplementation with a carotenoid mixture. Am J Clin Nutr 59:896-899
10. Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams WA, Moore BJ, Erdman JW (1996) Cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers & Prev 5:823-833
11. Craft NE, Wise SA (1993) Individual carotenoid content of SRM 1548 total diet and influence of storage temperature, lyophilization, and irradiation on dietary carotenoids. J Agric Food Chem 41:208-213
12. Davies B (1976) In: Chemistry and Biochemistry of Plant Pigments. Goodwin TW (ed): Academic Press, New York, Vol II, pp 38-165
13. Eichholzer M, Stahelin HB, Gey KF, Ludin E, Bernasconi F (1996) Prediction of male cancer mortality by plasma levels of interacting vitamins: 17-year follow-up of the prospective Basel study. Int J Cancer 66:145-150
14. Erdman JW, Bierer TL, Gugger ET. Absorption and Transport of Carotenoids. In: Canfield LM, Krinsky NI, Olson JA, eds. Carotenoids in Human Health. New York: The New York Academy of Sciences, 1993:76-85
15. Fuhrman B, Elis A, Aviram M (1997) Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem Biophys Res Commun 233:658-662
16. Gärtner C, Stahl W, Sies H (1996) Preferential increase in chylomicron levels of the xanthophylls lutein and zeaxanthin compared to beta-carotene in the human. Internat J Vit Nutr Res 66:119-125
17. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC (1995) Intake of carotenoids and retinol in relation to risk of prostate cancer. J Nat Cancer Inst 87:1767-1776
18. Halliwell B (1997) Antioxidants: The basics - what they are and how to evaluate them. In: Sies H (ed) Antioxidants in Disease Mechanisms and Therapy. San Diego: Academic Press Inc. pp 3-20
19. Johnson EJ, Qin J, Krinsky NI, Russell RM (1997) Ingestion by men of a combined dose of beta-carotene and lycopene does not affect the absorption of beta-carotene but improves that of lycopene. J Nutr 127:1833-1837
20. Khachik F, Beecher GR, Goli MB, Lusby WR, Smith JC (1992) Separation and identification of carotenoids and their oxidation products in the extracts of human plasma. Anal Chem 64:2111-2122
21. Khachik F, Beecher GR, Smith JC (1996) Lutein, lycopene, and their oxidative metabolites in chemoprevention of cancer. J Cell Biochem 22 (supplement):236-246
22. Kjosen H, Liaaenen-Jensen S (1972) Carotenoids of higher plants. Acta Chem Scand 26:4121-4129
23. Kohlmeier L, Kark JD, GomezGracia E, Martin BC, Steck SE, Kardinaal AFM, Ringstad J, Thamm M, Masaev V, Riemersma R, MartinMoreno JM, Huttunen JK, Kok FJ (1997) Lycopene and myocardial infarction risk in the EURAMIC Study. Am J Epidemiol 146:618-626
24. Kostic D, White WS, Olson JA (1995) Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses. Am J Clin Nutr 62:604-610
25. Krinsky NI (1989) Antioxidant functions of carotenoids. Free Rad Biol & Med 7:617-635
26. Mayne ST (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 10:690-701
27. Micozzi MS, Brown ED, Edwards BK, Bieri JG, Taylor PR, Khachik F, Beecher GR, Smith JC (1992) Plasma carotenoid response to chronic intake of selected foods and beta-carotene supplements in men. Am J Clin Nutr 55:1120-1125
28. Mortensen A, Skibsted LH (1997) Importance of carotenoid structure in radical-scavenging reactions. J Agric Food Chem 45:2970-2977
29. Müller H (1997) Determination of the carotenoid content in selected vegetables and fruit by HPLC and photodiode array detection. Z Lebensm Unters Forsch A 204:88-94
30. Müller H (1996) Die tägliche Aufnahme von Carotinoiden (Carotine and Xanthophylle) aus Gesamtnahrungsproben und die Carotinoidgehalte ausgewählter Gemüse- und Obstarten. Z Ernährungswiss 35:45-50
31. Omenn GS, Goodman GE, Thornquist M, Grizzle J, Rosenstock L, Barnhart S (1996) Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 334:1150-1155
32. Parker RS (1996) Absorption, metabolism, and transport of carotenoids. FASEB J 10:542-551
33. Pool-Zobel BL, Bub A, Müller H, Wollowski I, Rechkemmer G (1997) Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Carcinogenesis 18:1847-1850
34. Schierle J, Bretzel W, Bühler I, Faccin N, Hess D, Steiner K, Schüep W (1997) Content and isomeric ratio of lycopene in food and human blood plasma. Food Chem 59:459-465
35. Schmitz HH, Schwartz SJ, Catignani GL (1994) Resolution and quantitation of the predominant geometric beta-carotene isomers present in human serum using normal-phase HPLC. J Agric Food Chem 42:2746-2750
36. Scott KJ, Thurnham DI, Hart DJ, Bingham SA, Day K (1996) The correlation between the intake of lutein, lycopene and beta-carotene from vegetables and fruits, and blood plasma concentrations in a group of women aged 50-60 years in the UK. Br J Nutr 75:409-418
37. Shaish A, Daugherty A, Osullivan F, Schonfeld G, Heinecke JW (1995) Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits. J Clin Invest 96:2075-2082
38. Stahl W, Schwarz W, Laar Jv, Sies H (1995) All-trans beta-carotene preferentially accumulates in human chylomicrons and very low density lipoproteins compared with the 9-cis geometrical isomer. J Nutr 125:2128-2133
39. Stahl W, Sies H (1992) Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. J Nutr 122:2161-2166
40. Stahl W, Sies H (1996) Perspectives in biochemistry and biophysics. Lycopene: a biologically important carotenoid for humans? Arch Biochem Biophys 336:1-9
41. Steinmetz KA, Potter JD (1991) Vegetables, fruit, and cancer: II. Mechanisms. Cancer Causes & Control 2:427-442
42. Tamai H, Morinobu T, Murata T, Manago M, Mino M (1995) 9-cis-beta-carotene in human plasma and blood cells after ingestion of beta-carotene. Lipids 30:493-498
43. Truscott TG (1991) The photophysics and photochemistry of the carotenoids: the singlet oxygen and carotenoid interaction. J Photochem Photobiol B Biol 11:41-48
44. Yeum KJ, Booth SL, Sadowski JA, Liu C, Tang G, Krinsky NI, Russell RM (1996) Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables. Am J Clin Nutr 64:594-602
45. You CS, Parker RS, Goodman KJ, Swanson JE, Corso TN (1996) Evidence of cis-trans isomerization of 9-cis-beta-carotene during absorption in humans. Am J Clin Nutr 64:177-183