Lithium attenuates nerve growth factor-induced activation of AP-1 DNA binding activity in PC12 cells

Neuropsychopharmacology

Volumn 17, Issue 1, 1997, Pages 12-17

  Unlap, M Tino ^a   Jope, Richard S ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

AP 1; Bipolar disorder; CRE; Fos; Immediate early genes; Jun; Lithium

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LITHIUM; NERVE GROWTH FACTOR; PROTEIN C FOS; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DOSE TIME EFFECT RELATION; DRUG INHIBITION; GENE EXPRESSION; IMMEDIATE EARLY GENE; IMMUNOBLOTTING; MANIC DEPRESSIVE PSYCHOSIS; MODEL; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; RAT;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; BLOTTING, WESTERN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA; DRUG ANTAGONISM; FORSKOLIN; LITHIUM CHLORIDE; NERVE GROWTH FACTORS; PC12 CELLS; RATS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

EID: 0030954414     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(97)00020-1     Document Type: Article

References (19)

1. Arenander AT, de Vellis J, Herschman HR (1989): Induction of c-fos and TIS genes in cultured rat astrocytes by neurotransmitters. J Neurosci Res 24:107-114
2. Bradford MM (1976): A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
3. Burstein DE, Seely PJ, Green LA (1985): Lithium ion inhibits nerve growth factor-induced neurite outgrowth and phosphorylation of nerve growth factor-modulated microtubule-associated proteins. J Cell Biol 101:862-870
4. Colin SF, Chang H-C, Mollner S, Pfeuffer T, Reed RR, Duman RS, Nestler EJ (1991): Chronic lithium regulates the expression of adenylate cyclase and Gi-protein α-subunit in rat cerebral cortex. Proc Natl Acad Sci USA 88:10634-10637
5. Dignam JD, Martin PL, Shastry BS, Roeder RG (1983): Eukaryotic gene transcription with purified components. Methods Enzymol 101:582-598
6. Divish MM, Sheftel G, Boyle A, Kalasapudi VD, Papolos DF, Lachman HM (1991): Differential effect of lithium on fos protooncogene expression mediated by receptor and postreceptor activators of protein kinase C and cyclic adenosine monophosphate: Model for its antimanic action. J Neurosci Res 28:40-48
7. Greenberg ME, Green LA, Ziff EB (1985): Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem 260:14101-14110
8. Heninger GR, Delgado PL, Charney DS (1996): The revised monoamine theory of depression: A modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans. Pharmacopsychiatry 29:2-11
9. Jope RS, Williams MB (1994): Lithium and brain signal transduction systems. Biochem Pharmacol 47:429-441
10. Kalasapudi VD, Sheftel G, Divish MM, Papolos DF, Lachman HM (1990): Lithium augments fos protooncogene expression in PC12 pheochromocytoma cells: Implications for therapeutic action of lithium. Brain Res 421:47-54
11. Li PP, Tam Y-K, Young LT, Warsh JJ (1991): Lithium decreases Gs, Gi-1 and Gi-2 α-subunit mRNA levels in rat cortex. Eur J Pharmacol 206:165-166
12. Li X, Jope RS (1995): Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J Neurochem 65:2500-2508
13. Manji HK, Lenox RH (1994): Long-term action of lithium: A role for transcriptional and posttranscriptional factors regulated by protein kinase C. Synapse 16:11-28
14. Morgan JI, Curran T (1991): Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci 14:421-451
15. Nibuya M, Morinobu S, Duman RS (1995): Regulation of BDNF and trkB mRNA in rat brain by chronic electro-convulsive seizure and antidepressant drug treatments. J Neurosci 15:7539-7547
16. Szeberényi J, Erhardt P (1994): Cellular components of nerve growth factor signaling. Biochim Biophys Acta 1222: 187-202
17. Unlap T, Jope RS (1995): Diurnal variation in kainate-induced AP-1 activation in rat brain: Influence of glucocorticoids. Mol Brain Res 28:193-200
18. Wang J-F, Young LT (1996): Differential display PCR reveals increased expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase by lithium. FEBS Lett 386:225-229
19. Williams MB, Jope RS (1995): Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: Modulation by lithium. Psychopharmacology 122: 363-368