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Volumn 116, Issue 2, 1999, Pages 307-315

Early reduction of the over-expression of CD40L, OX40 and Fas on T cells in HIV-1 infection during triple anti-retroviral therapy: Possible implications for lymphocyte traffic and functional recovery

Author keywords

Anti retroviral therapy; CD40L; Fas; HIV 1 infection; OX40

Indexed keywords

ANTIRETROVIRUS AGENT; CD40 ANTIGEN; FAS ANTIGEN; LAMIVUDINE; NELFINAVIR; STAVUDINE; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0032894849     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00872.x     Document Type: Article
Times cited : (34)

References (47)
  • 2
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • 2 Autran B, Carcelain G, Li TS et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Sci 1997; 277:112-6.
    • (1997) Sci , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Li, T.S.3
  • 3
    • 16944367032 scopus 로고    scopus 로고
    • HIV infection induces changes in CD4+ T cell phenotype and depletions within the CD4+ T cell repertoire that are not immediately restored by antiviral or immune-based therapies
    • 3 Connors M, Kovacs JA, Krevat S et al. HIV infection induces changes in CD4+ T cell phenotype and depletions within the CD4+ T cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nature Med 1997; 3:533-40.
    • (1997) Nature Med , vol.3 , pp. 533-540
    • Connors, M.1    Kovacs, J.A.2    Krevat, S.3
  • 4
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation
    • 4 Pakker NG, Notermans DW, Boer RJ et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nature Med 1998; 4:208-14.
    • (1998) Nature Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    Boer, R.J.3
  • 5
    • 0031873665 scopus 로고    scopus 로고
    • Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy
    • 5 Fleury S, Boer RJ, Rizzardi GP et al. Limited CD4+ T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy. Nature Med 1998; 4:794-801.
    • (1998) Nature Med , vol.4 , pp. 794-801
    • Fleury, S.1    Boer, R.J.2    Rizzardi, G.P.3
  • 6
    • 0031907427 scopus 로고    scopus 로고
    • Perturbation of CD4+ and CD8+ T cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy
    • 6 Gorochov G, Neumann AU, Kereveur A et al. Perturbation of CD4+ and CD8+ T cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nature Med 1998; 4:215-21.
    • (1998) Nature Med , vol.4 , pp. 215-221
    • Gorochov, G.1    Neumann, A.U.2    Kereveur, A.3
  • 7
    • 0031883405 scopus 로고    scopus 로고
    • Getting to the HAART of T cell dynamics
    • 7 Roederer M. Getting to the HAART of T cell dynamics. Nature Med 1998; 4:145-6.
    • (1998) Nature Med , vol.4 , pp. 145-146
    • Roederer, M.1
  • 8
    • 0031889951 scopus 로고    scopus 로고
    • Rapid CD4+ T cell turnover in HIV-1 infection: A paradigm revisited
    • 8 Wolthers KC, Sehuitemaker H, Miedema F, Rapid CD4+ T cell turnover in HIV-1 infection: a paradigm revisited. Immunol Today 1998; 19:44-48.
    • (1998) Immunol Today , vol.19 , pp. 44-48
    • Wolthers, K.C.1    Sehuitemaker, H.2    Miedema, F.3
  • 9
    • 0031935076 scopus 로고    scopus 로고
    • HIV-induced decline in blood CD4/CD8 ratios: Viral killing or altered lymphocyte trafficking?
    • 9 Rosenberg JY, Anderson AO, Pabst R. HIV-induced decline in blood CD4/CD8 ratios: viral killing or altered lymphocyte trafficking? Immunol Today 1998; 19:10-17.
    • (1998) Immunol Today , vol.19 , pp. 10-17
    • Rosenberg, J.Y.1    Anderson, A.O.2    Pabst, R.3
  • 10
    • 0030726383 scopus 로고    scopus 로고
    • Host factors in the pathogenesis of HIV disease
    • 10 Cohen OJ, Kinter A, Fauci AS. Host factors in the pathogenesis of HIV disease. Immunol Rev 1997; 159:31-48.
    • (1997) Immunol Rev , vol.159 , pp. 31-48
    • Cohen, O.J.1    Kinter, A.2    Fauci, A.S.3
  • 12
    • 0029882175 scopus 로고    scopus 로고
    • Programmed cell death in peripheral lymphocytes from HIV-infected persons: The increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression
    • 12 Gougeon ML, Lecoeur H, Dulioust A, Enouf MG, Crouvoisier M, Goujard C, Debord T, Montagnier L. Programmed cell death in peripheral lymphocytes from HIV-infected persons: the increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J Immunol 1996; 156:3509-20.
    • (1996) J Immunol , vol.156 , pp. 3509-3520
    • Gougeon, M.L.1    Lecoeur, H.2    Dulioust, A.3    Enouf, M.G.4    Crouvoisier, M.5    Goujard, C.6    Debord, T.7    Montagnier, L.8
  • 13
    • 0030668834 scopus 로고    scopus 로고
    • Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression
    • 13 Liu Z, Cumberland WG, Hultin LF, Prince HE, Detels R, Giorgi JV, Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovir 1997; 16:83-92.
    • (1997) J Acquir Immune Defic Syndr Hum Retrovir , vol.16 , pp. 83-92
    • Liu, Z.1    Cumberland, W.G.2    Hultin, L.F.3    Prince, H.E.4    Detels, R.5    Giorgi, J.V.6
  • 14
    • 0028020169 scopus 로고
    • Analysis of lymphocyte cell death and apoptosis in HIV2 infected patients
    • 14 Jaleco A, Covas MJ, Victorino RMM. Analysis of lymphocyte cell death and apoptosis in HIV2 infected patients. Clin Exp Immunol 1994; 18:185-9.
    • (1994) Clin Exp Immunol , vol.18 , pp. 185-189
    • Jaleco, A.1    Covas, M.J.2    Victorino, R.M.M.3
  • 16
    • 0031569286 scopus 로고    scopus 로고
    • Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype
    • 16 Gougeon M-L, Lecoeur H, Boudet V et al. Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype. J Immunol 1997; 158:2964-76.
    • (1997) J Immunol , vol.158 , pp. 2964-2976
    • Gougeon, M.-L.1    Lecoeur, H.2    Boudet, V.3
  • 17
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • 17 Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996; 334:1717-25.
    • (1996) N Engl J Med , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 18
    • 0028927607 scopus 로고
    • The Fas death factor
    • 18 Nagata S, Golstein ML. The Fas death factor. Sci 1995; 267:1449-56.
    • (1995) Sci , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, M.L.2
  • 19
    • 0029048581 scopus 로고
    • Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
    • 19 Katsikis PD, Wunderlich ES, Smith C, Herzenberg LA, Herzenberg LA. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 1995; 181:2029-36.
    • (1995) J Exp Med , vol.181 , pp. 2029-2036
    • Katsikis, P.D.1    Wunderlich, E.S.2    Smith, C.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 20
    • 0028298229 scopus 로고
    • gp39 -CD40 interactions are essential for germinal center formation and the development of B cell memory
    • 20 Foy TM, Laman JD, Ledbetter JA, Aruffo A, Claassen E, Noelle RJ. gp39 -CD40 interactions are essential for germinal center formation and the development of B cell memory. J Exp Med 1994; 180:157-63.
    • (1994) J Exp Med , vol.180 , pp. 157-163
    • Foy, T.M.1    Laman, J.D.2    Ledbetter, J.A.3    Aruffo, A.4    Claassen, E.5    Noelle, R.J.6
  • 21
    • 0029938992 scopus 로고    scopus 로고
    • The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
    • 21 Stuber E, Strober W. The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. J Exp Med 1996; 183:979-89.
    • (1996) J Exp Med , vol.183 , pp. 979-989
    • Stuber, E.1    Strober, W.2
  • 22
    • 0029928929 scopus 로고    scopus 로고
    • Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis
    • 22 Blotta MH, Marshall JD, DeKruyff RH, Umetsu DT. Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis. J Immunol 1996; 156:3133-40.
    • (1996) J Immunol , vol.156 , pp. 3133-3140
    • Blotta, M.H.1    Marshall, J.D.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 23
    • 1842335746 scopus 로고    scopus 로고
    • CD40 ligation on human cord blood CD34+ hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells
    • 23 Flores-Romo L, Bjork P, Ouvert V, Van Kooten C, Saeland S, Banchereau J. CD40 ligation on human cord blood CD34+ hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J Exp Med 1997; 185:341-9.
    • (1997) J Exp Med , vol.185 , pp. 341-349
    • Flores-Romo, L.1    Bjork, P.2    Ouvert, V.3    Van Kooten, C.4    Saeland, S.5    Banchereau, J.6
  • 25
    • 0029895222 scopus 로고    scopus 로고
    • The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells
    • 25 Imura A, Hori T, Imada K, Ishikawa T, Tanaka Y, Maeda M, Imamura S, Uchiyama T. The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells. J Exp Med 1996; 183:2185-95.
    • (1996) J Exp Med , vol.183 , pp. 2185-2195
    • Imura, A.1    Hori, T.2    Imada, K.3    Ishikawa, T.4    Tanaka, Y.5    Maeda, M.6    Imamura, S.7    Uchiyama, T.8
  • 26
    • 0028783397 scopus 로고
    • Functional interactions of T cells with endothelial cells: The role of CD40L-CD40-mediated signals
    • 26 Yellin MJ, Brett J, Baum D, Malsushima A, Szabolcs M, Stern D, Chess L. Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals. J Exp Med 1995; 182:1857-64.
    • (1995) J Exp Med , vol.182 , pp. 1857-1864
    • Yellin, M.J.1    Brett, J.2    Baum, D.3    Malsushima, A.4    Szabolcs, M.5    Stern, D.6    Chess, L.7
  • 27
    • 13344283418 scopus 로고    scopus 로고
    • Selective depletion of myclin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis
    • 27 Weinberg AD, Bourdette DN, Sullivan TJ et al. Selective depletion of myclin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis. Nature Med 1996; 2:183-9.
    • (1996) Nature Med , vol.2 , pp. 183-189
    • Weinberg, A.D.1    Bourdette, D.N.2    Sullivan, T.J.3
  • 28
    • 0029913381 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production
    • 28 Desai-Mehta A, Lu L, Ramsey-Goldman R, Datta S. Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 1996; 97:2063-73.
    • (1996) J Clin Invest , vol.97 , pp. 2063-2073
    • Desai-Mehta, A.1    Lu, L.2    Ramsey-Goldman, R.3    Datta, S.4
  • 29
    • 0030947611 scopus 로고    scopus 로고
    • Expression of the T-cell activation antigen, OX-40, identifies alloreactive T cells in acute graft-versus-host disease
    • 29 Tittle TV, Weinberg AD, Steinkeler CN, Maziarz RT. Expression of the T-cell activation antigen, OX-40, identifies alloreactive T cells in acute graft-versus-host disease. Blood 1997; 89:4652-8.
    • (1997) Blood , vol.89 , pp. 4652-4658
    • Tittle, T.V.1    Weinberg, A.D.2    Steinkeler, C.N.3    Maziarz, R.T.4
  • 30
    • 0030659503 scopus 로고    scopus 로고
    • The CD40 pathway in allograft rejection, acceptance and tolerance
    • 30 Larsen CP, Pearson TC. The CD40 pathway in allograft rejection, acceptance and tolerance. Cur Opin Immunol 1997; 9:641-7.
    • (1997) Cur Opin Immunol , vol.9 , pp. 641-647
    • Larsen, C.P.1    Pearson, T.C.2
  • 31
    • 0030870889 scopus 로고    scopus 로고
    • CD40 CD40 ligand interaction in autoimmune disease
    • 31 Datta SK, Kalled SL. CD40 CD40 ligand interaction in autoimmune disease. Arthritis Rheum 1997; 40:1735-45.
    • (1997) Arthritis Rheum , vol.40 , pp. 1735-1745
    • Datta, S.K.1    Kalled, S.L.2
  • 32
    • 0032519890 scopus 로고    scopus 로고
    • Evidence for a continued requirement for CD40/CD40 ligand (CD154) interactions in the progression of LP-BM5 retrovirus-induced murine AIDS
    • 32 Green K, Noelle RJ, Green WR. Evidence for a continued requirement for CD40/CD40 ligand (CD154) interactions in the progression of LP-BM5 retrovirus-induced murine AIDS. Virology 1998; 241: 260-8.
    • (1998) Virology , vol.241 , pp. 260-268
    • Green, K.1    Noelle, R.J.2    Green, W.R.3
  • 33
    • 0020643306 scopus 로고
    • Natural resistance to parental T-lymphocyte-induced immunosuppression in F hybrid mice: Implications for acquired immune deficiency syndrome (AIDS)
    • 33 Shearer GM. Natural resistance to parental T-lymphocyte-induced immunosuppression in F hybrid mice: implications for acquired immune deficiency syndrome (AIDS). Immunol Rev 1983; 73:115-26.
    • (1983) Immunol Rev , vol.73 , pp. 115-126
    • Shearer, G.M.1
  • 34
    • 0027989940 scopus 로고
    • Panel of anti-gp120 monoclonal antibodies reacts wilh same nuclear proteins in uninfected cells as those recognised by autoantibodies from patients with systemic lupus erythematosus
    • 34 Pinto LA, Dalgleish AG, Sumar N, Poulton TA. Panel of anti-gp120 monoclonal antibodies reacts wilh same nuclear proteins in uninfected cells as those recognised by autoantibodies from patients with systemic lupus erythematosus. AIDS Res Hum Retrovir 1994; 10:823-8.
    • (1994) AIDS Res Hum Retrovir , vol.10 , pp. 823-828
    • Pinto, L.A.1    Dalgleish, A.G.2    Sumar, N.3    Poulton, T.A.4
  • 36
    • 0029073133 scopus 로고
    • CD40 on human endothelial cells: Inducibility by cytokines and functional regulation of adhesion molecule expression
    • 36 Karmann K, Hughes CC, Schechner J, Fanslow WC, Pober JS. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc Natl Acad Sci USA 1995; 92:4342-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4342-4346
    • Karmann, K.1    Hughes, C.C.2    Schechner, J.3    Fanslow, W.C.4    Pober, J.S.5
  • 37
    • 0031875614 scopus 로고    scopus 로고
    • HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy
    • 37 Morris L, Binley JM, Clas BA et al. HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy. J Exp Med 1998; 188:233-45.
    • (1998) J Exp Med , vol.188 , pp. 233-245
    • Morris, L.1    Binley, J.M.2    Clas, B.A.3
  • 38
    • 7144229335 scopus 로고    scopus 로고
    • Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease
    • 38 Piketty C, Castiel P, Belec T. et al. Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease. AIDS 1998; 12:745-50.
    • (1998) AIDS , vol.12 , pp. 745-750
    • Piketty, C.1    Castiel, P.2    Belec, T.3
  • 39
    • 0031951027 scopus 로고    scopus 로고
    • Early increase of CD4+CD45RA+ and CD4+CD95 cells with conserved repertoire induced by anti-retroviral therapy in HIV-infected patients
    • 39 Silvestri G, Munoz-Calleja C, Bagnarelli P, Piedionte G, Clementi M, Montroni M. Early increase of CD4+CD45RA+ and CD4+CD95 cells with conserved repertoire induced by anti-retroviral therapy in HIV-infected patients. Clin Exp Immunol 1998; 111:3-11.
    • (1998) Clin Exp Immunol , vol.111 , pp. 3-11
    • Silvestri, G.1    Munoz-Calleja, C.2    Bagnarelli, P.3    Piedionte, G.4    Clementi, M.5    Montroni, M.6
  • 40
    • 0032128437 scopus 로고    scopus 로고
    • In vivo analysis of Fas/ PasL interactions in HIV-infected patients
    • 40 Badley AD, Dockrell DH, Algeciras A et al. In vivo analysis of Fas/ PasL interactions in HIV-infected patients. J Clin Invest 1998; 102:79-87.
    • (1998) J Clin Invest , vol.102 , pp. 79-87
    • Badley, A.D.1    Dockrell, D.H.2    Algeciras, A.3
  • 42
    • 0031903406 scopus 로고    scopus 로고
    • Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease
    • 42 Kaplan D, Sieg S. Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease. J Virol 1998; 72:6279-82.
    • (1998) J Virol , vol.72 , pp. 6279-6282
    • Kaplan, D.1    Sieg, S.2
  • 43
    • 0031985139 scopus 로고    scopus 로고
    • Suppression of immune responses by CD8 cells. I Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells
    • 43 Noble A, Pestano GA, Cantor II. Suppression of immune responses by CD8 cells. I Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. J Immunol 1998; 159:559-65.
    • (1998) J Immunol , vol.159 , pp. 559-565
    • Noble, A.1    Pestano, G.A.2    Cantor, I.I.3
  • 44
    • 0031973637 scopus 로고    scopus 로고
    • Maximal proliferation of cytotoxic T lymphocytes requires reverse signalling through Fas ligand
    • 44 Suzuki I. Fink PJ. Maximal proliferation of cytotoxic T lymphocytes requires reverse signalling through Fas ligand. J Exp Med 1998; 187:123-8.
    • (1998) J Exp Med , vol.187 , pp. 123-128
    • Suzuki, I.1    Fink, P.J.2
  • 46
    • 0033559879 scopus 로고    scopus 로고
    • Kinetics of the changes of lymphocyte subsets defined by cytokine production at single cell level during highly active antiretroviral therapy for HIV 1 infection
    • in press
    • 46 Sousa AE, Chaves AF, Doroana M, Antunes F, Victorino RMM. Kinetics of the changes of lymphocyte subsets defined by cytokine production at single cell level during highly active antiretroviral therapy for HIV 1 infection. J Immunol 1999; 162: (in press).
    • (1999) J Immunol , vol.162
    • Sousa, A.E.1    Chaves, A.F.2    Doroana, M.3    Antunes, F.4    Victorino, R.M.M.5
  • 47
    • 0029812505 scopus 로고    scopus 로고
    • Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection
    • 47 Rosok BI, Boetad L, Voltersik P, Berknes R, Olofsson J. Asjo B, Brinchmann JE. Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection. AIDS 1996; 10:F35-F38.
    • (1996) AIDS , vol.10
    • Rosok, B.I.1    Boetad, L.2    Voltersik, P.3    Berknes, R.4    Olofsson, J.5    Asjo, B.6    Brinchmann, J.E.7


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