The human OX40/GP34 system directly mediates adhesion of activated T cells to vascular endothelial cells

Journal of Experimental Medicine

Volumn 183, Issue 5, 1996, Pages 2185-2195

  Imura, Akihiro ^a   Hori, Toshiyuki ^a   Imada, Kazunori ^a   Ishikawa, Takayuki ^a   Tanaka, Yuetsu ^b   Maeda, Michiyuki ^a   Imamura, Sadao ^a   Uchiyama, Takashi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; NERVE GROWTH FACTOR; PHYTOHEMAGGLUTININ; TUMOR NECROSIS FACTOR;

ARTICLE; CELL ADHESION; DNA SEQUENCE; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNIZATION; LEUKEMIA CELL; LYMPHOCYTE TRANSFORMATION; MOLECULAR CLONING; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD27; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; DNA PRIMERS; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; GENE LIBRARY; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; LEUKEMIA, T-CELL; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, OX40; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TRANSFECTION; TUMOR CELLS, CULTURED; UMBILICAL VEINS;

EID: 0029895222     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.5.2185     Document Type: Article

References (62)

1. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-349.
2. Gallatin, W.M., I.L. Weissman, and E.C. Butcher. 1983. A cell surface molecule involved in organ-specific homing of lymphocytes. Nature (Lond.). 304:30-34.
3. Bjerknes, M., H. Cheng, and C.A. Ottaway. 1986. Dynamics of lymphocyte-endothelial interactions in vivo. Science (Wash. DC). 231:402-405.
4. Gallatin, M., T.P.S. John, M. Siegelman, R. Reichert, E.C. Butcher, and I.L. Weissman. 1986. Lymphocyte homing receptors. Cell. 44:673-802.
5. Stoolman, L.M. 1989. Adhesion molecules controlling lymphocyte migration. Cell. 56:907-910.
6. Osborn, L. 1990. Leukocyte adhesion to endothelium in inflammation. Cell. 62:3-6.
7. Springer. T.A. 1990. Adhesion receptors of the immune system. Nature (Lond.). 346:425-434.
8. Butcher, E.C. 1991. Leukocyte-endothelial cell recognition; three (or more) steps to specificity and diversity. Cell. 67: 1033-1066.
9. Shimizu, Y., W. Newman, Y. Tanaka, and S. Shaw. 1992. Lymphocyte interactions with endothelial cells. Immunol. Today. 13:106-112.
10. Picker, L.J., J.R. Treer, B. Ferguson-Darnell, P.A. Collins, D. Buck, and L.W.M.M. Terstappen. 1993. Control of lymphocyte recirculation in man. J. Immunol. 150:1105-1121.
11. Adams, D.H., and S. Shaw. 1994. Leukocyte-endothelial interactions and regulation of leukocyte migration. Lancet. 343: 831-836.
12. Diamond, M.S., and T.A. Springer. 1994. The dynamic regulation of integrin adhesiveness. Curr. Biol. 4:506-517.
13. Berg, E.L., T. Yoshino, L.S. Rott, M.K. Robinson, R.A. Warnock, T.K. Kishimoto, L.J. Picker, and E.C. Butcher. 1991. The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1. J. Exp. Med. 174:1461-1466.
14. Picker, L.J., T.K. Kishimoto, C.W. Smith, R.A. Warnock, and E.C. Butcher. 1991. ELAM-1 is an adhesion molecule for skin-homing T cells. Nature (Lond.). 349:796-799.
15. Shimizu, Y., S. Shaw, N. Graber, T.V. Gopal, K.J. Horgan, G.A. Van Seventer, and W. Newman. 1991. Activation-independent binding of human T cells to adhesion molecule ELAM-1. Nature (Lond.). 349:799-802.
16. Steegmaler, M., A. Levinovitz, S. Isenmann, E. Borges, M. Lenter, H.P. Kocher, B. Kleuser, and D. Vestweber. 1995. The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. Nature (Lond.). 373:615-620.
17. van Kooyk, Y., E. van de Wiel-van Kemenade, P. Weder, R.J.F. Huijbens, and C.G. Figdor. 1993. Lymphocyte function-associated antigen 1 dominates very late antigen 4 in binding of activated T cells to endothelium. J. Exp. Med. 177:185-190.
18. Bowen, M.A., D.D. Patel, X. Li, B. Modrell, A.R. Malacko, W. Wang, H. Marquardt, M. Neubauer, J.M. Pesando, U. Francke, B.F. Haynes, and A. Aruffo. 1995. Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J. Exp. Med. 181: 2213-2220.
19. Peach, R.J., D. Hollenbaugh, I. Stamenkovic, and A. Aruffo. 1993. Identification of hyaluronic acid binding sites in the extracellular domain of CD44. J. Cell Biol. 122:257-264.
20. Haynes, B.F., M.J. Telen, L.P. Hale, and S.M. Denning. 1989. CD44-A molecule involved in leukocyte adherence and T-cell activation. Immunol. Today. 10:423-428.
21. Koopman, G., Y.V. Kooyk, M.D. Graaf, C.J.L.M. Meyer, C.G. Figdor, and S.T. Pals. 1990. Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA-1 pathway. J. Immunol. 145:3589-3593.
22. Gunthert, U., M. Hofmann, W. Rudy, S. Reber, M. Zoller, I. Haussmann, S. Matzku, A. Wenzel, H. Ponta, and P. Herrlich. 1991. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell. 65:13-24.
23. Vennegoor, C.J.G.M., E. van de Wiel-van Kemenade, R.J.F. Huijbens, F. Sanchez-Madrid, C.J.M. Melief, and C.G. Figdor. 1992. Role of LFA-1 and VLA-4 in the adhesion of cloned normal and LFA-1 (CD11/CD18)-deficient T cells to cultured endothelial cells. Indication for a new adhesion pathway. J. Immunol. 148:1093-2001.
24. Wagner, N., P. Engel, and T.F. Tedder. 1993. Regulation of the tyrosine kinase-dependent adhesion pathway in human lymphocytes through CD45. J. Immunol. 150:4887-4899.
25. Uchiyaina, T., J. Yodoi, K. Sagawa, K. Takatsuki, and H. Uchino. 1977. Adult T cell leukemia: clinical and hematologic features of 16 cases. Blood. 50:481-492.
26. Uchiyama, T. 1988. Adult T cell leukemia. Blood Rev. 2: 232-238.
27. Ishikawa, T., A. Imura, K. Tanaka, H. Shirane, M. Okuma, and T. Uchiyama. 1993. E-selectin and vascular cell adhesion molecule-1 mediate adult T-cell leukemia cell adhesion to endothelial cells. Blood. 82:1590-1598.
28. Uchiyama, T., T. Ishikawa, and A. Imura. 1995. Adhesion properties of adult T cell leukemia cells. Leuk. & Lymphoma. 16:407-412.
29. Chuluyan, H.E., T.J. Schall, T. Yoshimura, and A.C. Issekutz. 1995. IL-1 activation of endothelium supports VLA-4 (CD49d/CD29)-mediated monocyte transendothelial migration to C5a, MIP-1 α, RANTES, and PAF but inhibits migration to MCP-1: a regulatory role for endothelium-derived MCP-1. J. Leukocyte Biol. 58:71-79.
30. Issekutz, T.B. 1995. In vivo blood monocyte migration to acute inflammatory reactions, IL-1 α, TNF-α, IFN-γ, and C5a utilizes LFA-1, Mac-1, and VLA-4. The relative importance of each integrin. J. Immunol. 154: 6533-6540.
31. + T cells. J. Exp. Med. 180:2125-2135.
32. Hynes, R.O. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 69:11-25.
33. + positive haemopoietic cells: biology and clinical applications. Blood Rev. 8:113-124.
34. Lin, T.H., C. Rosales, K. Mondal, J.B. Bolen, S. Haskill, and R.L. Juliano. 1995. Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase. J. Biol. Chem. 270:16189-16197.
35. Lo, S.K., A. Cheung, Q. Zheng, and R.L. Silverstein. 1995. Induction of tissue factor on monocytes by adhesion to endothelial cells. J. Immunol. 154:4768-4777.
36. Pfau. S., D. Leitenberg, H. Rinder, B.R. Smith, R. Pardi, and J.R. Bender. 1995. Lymphocyte adhesion-dependent calcium signaling in human endothelial cells. J. Cell Biol. 128: 969-978.
37. Mainiero, F., A. Pepe, K.K. Wary, L. Spinardi, M. Mohammadi, J. Schlessinger, and F.G. Giancotti. 1995. Signal transduction by the α6β4 integrin: distinct β4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. EMBO (Eur. Mol. Biol. Organ.) J. 14:4470-4481.
38. Simulons, P.J., D.I. Leavesley, J.P. Levesque, B.W. Swart, D.N. Haylock, L.B. To, L.K. Ashman, and C.A. Juttner. 1994. The mobilization of primitive hemopoietic progenitors into the peripheral blood. Stem Cells. 12:187-201.
39. Galli, S.J., M. Tsai, and B.K. Wershil. 1993. The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others. Am. J. Pathol. 142:965-974.
40. Paterson, D.J., W.A. Jefferies, J.R. Green, M.R. Brandon, P. Corthesy, M. Puklavic, and A.F. Williams. 1987. Antigens of activated rat lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol. Immunol. 24: 1281-1290.
41. Mallett, S., S. Fossum, and A.N. Barclay. 1990. Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes - a molecule related to nerve growth factor receptor. EMBO (Eur. Mol. Biol. Organ.) J. 9:1063-1068.
42. Baum, P.R., R.B. Gayle III, F. Ramsdell, S. Srinivasan, R.A. Sorensen, L.M. Watson, M.F. Seldin, E. Baker, G.R. Sutherland, K.N. Clifford, et al. 1994. Molecular characterization of murine and human OX40/OX40 ligand system: identification of a human OX40 ligand as the HTLV-I-regulated protein gp34. EMBO (Eur. Mol. Biol. Organ.) J. 13:3992-4001.
43. + T cells with homology to tumor necrosis factor J. Exp. Med. 180:757-762.
44. Tanaka, Y., I. Takeshi, N. Yamamoto, and Y. Hinuma. 1985. A glycoprotein antigen detected with new monoclonal antibodies on the surface of human lymphocytes infected with human T-cell leukemia virus type-I (HTLV-I). Int. J. Cancer. 36:549-555.
45. Tozawa, H., S. Andou, Y. Takayama, Y. Tanaka, B. Lee, H. Nakamura, M. Hayami, and Y. Hinuma. 1988. Species-dependent antigenicity of the 34-kDa glycoprotein found on the membrane of various primate lymphocytes transformed by human T-cell leukemia virus type-I (HTLV-I) and simian T-cell leukemia virus (STLV-I). Int. J. Cancer. 41:231-238.
46. tax. Mol. Cell. Biol. 11:1313-1325.
47. Hori, T., T. Uchiyama, M. Tsudo, H. Umadome, H. Ohno, S. Fukuhara, K. Kita, and H. Uchino. 1987. Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lyniphoma virus. Blood. 70:1069-1072.
48. Jaffe, E.A., R.L. Nachman, C.G. Becker, and C.R. Minik. 1973. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria J. Clin. Invest. 52:2745-2753.
49. Tsudo, M., F. Kitamura, and M. Miyasaka. 1989. Characterization of the interleukin 2 receptor β chain using three distinct monoclonal antibodies. Proc. Natl. Acad. Sci. USA. 86: 1982-1986.
50. Kondo, A., K. Imada, T. Hattori, H. Yamabe, T. Tanaka, M. Miyasaka, M. Okuma, and T. Uchiyama. 1993. A model of in vivo cell proliferation of adult T-cell leukemia. Blood. 82: 2501-2509.
51. Maruyama, K., and Y. Takebe. 1990. Recent advanced cDNA cloning. Med. Immunol. 20:27-30.
52. Seed, B. 1987. An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature (Lond.). 329:840-842.
53. Seed, U., and A. Arrufo. 1987. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA. 84:3365-3369.
54. Arrufo, A., and B. Seed. 1987. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA. 84:8573-8577.
55. Imada, K., T. Takaori-Kondo, T. Akagi, K. Shimotohno, K. Sugamura, T. Hattori, H. Yamabe, M. Okuma, and T. Uchiyama. 1995. Tumorigenicity of HTLV-I infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo. Blood. 86:2350-2357.
56. Calderhead, D.M., J.E. Buhlmann, A.J. van den Eertwegh, E. Claassen, R.J. Noelle, and H.P. Fell. 1993. Cloning of mouse OX40: a T cell activation marker that may mediate T-B cell interactions. J. Immunol. 151:5261-5271.
57. Latza, U., H. Dürkop, S. Schnittger, J. Ringeling, F. Eitelbach, M. Hummel, C. Fonatsch, and H. Stein. 1994. The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen. Cur. J. Immunol. 24:677-683.
58. Gruss, H.J., and S.K. Dower. 1995. Tumor necrosis factor ligand superfamily: Involvement in the pathology of malignant lymphomas. Blood. 85:3378-3404.
59. Cosman, D. 1994. A family of ligands for the TNF receptor superfamily. Stem Cells. 12:440-455.
60. Armitage, R.J. 1994. Tumor necrosis factor receptor superfamily members and their ligands. Curr. Opin. Immunol. 6: 407-413.
61. Stüber, E., M. Neurath, D. Calderhead, H.P. Fell, and W. Strober. 1995. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity. 2:507-521.
62. Hollenbaugh, D., N. Mischel-Petty, C.P. Edwards, J.C. Simon, R.W. Denfeld, P.A. Kiener, and A. Aruffo. 1995. Expression of functional CD40 by vascular endothelial cells. J. Exp. Med. 182:33-40.