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Volumn 3, Issue 5, 1997, Pages 533-540

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INDINAVIR; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEINASE INHIBITOR;

EID: 16944367032     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0597-533     Document Type: Article
Times cited : (481)

References (21)
  • 1
    • 0021792148 scopus 로고
    • Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome
    • Lane, H.C. et al. Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 313, 79-84 (1985).
    • (1985) N. Engl. J. Med. , vol.313 , pp. 79-84
    • Lane, H.C.1
  • 2
    • 0024272153 scopus 로고
    • Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men: HIV affects the immune system before CD4* T cell depletion occurs
    • Miedema, F. et al. Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men: HIV affects the immune system before CD4* T cell depletion occurs. J. Clin. Invest. 82, 1908-1914 (1988).
    • (1988) J. Clin. Invest. , vol.82 , pp. 1908-1914
    • Miedema, F.1
  • 3
    • 0024786954 scopus 로고
    • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients
    • Clerici, M. et al. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. J. Clin. Invest. 84, 1892-1899 (1989).
    • (1989) J. Clin. Invest. , vol.84 , pp. 1892-1899
    • Clerici, M.1
  • 4
    • 0025991477 scopus 로고
    • Human immunodeficiency virus infection in the US Air Force: Seroconversions, clinical staging and assessment of T helper cell functional assay to predict change in CD4* T cell counts
    • Lucey, D.R. et al. Human immunodeficiency virus infection in the US Air Force: Seroconversions, clinical staging and assessment of T helper cell functional assay to predict change in CD4* T cell counts. J. Infect. Dis. 164, 631-637 (1991).
    • (1991) J. Infect. Dis. , vol.164 , pp. 631-637
    • Lucey, D.R.1
  • 5
    • 0027476846 scopus 로고
    • Immunological memory
    • Gray, D. Immunological memory. Annu. Rev. Immunol. 11, 49-77 (1993).
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 49-77
    • Gray, D.1
  • 6
    • 0028253974 scopus 로고
    • The role of antigen in maintaining T cell memory
    • Zinkernagel, R.M. The role of antigen in maintaining T cell memory. Dev Biol. Stand. 82, 189-191 (1994).
    • (1994) Dev Biol. Stand. , vol.82 , pp. 189-191
    • Zinkernagel, R.M.1
  • 7
    • 0023934515 scopus 로고
    • Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production
    • Sanders, M.E. et al. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production. J. Immunol. 140, 1401-1407 (1988).
    • (1988) J. Immunol. , vol.140 , pp. 1401-1407
    • Sanders, M.E.1
  • 8
    • 0024341657 scopus 로고
    • Production of lymphokine mRNA by CD45R* and CD45R- Helper T cells from human peripheral blood and by human CD4* T cell clones
    • Salmon, M., Kitas, G.D. & Bacon, P.A. Production of lymphokine mRNA by CD45R* and CD45R- helper T cells from human peripheral blood and by human CD4* T cell clones. J. Immunol. 143, 907-912 (1989).
    • (1989) J. Immunol. , vol.143 , pp. 907-912
    • Salmon, M.1    Kitas, G.D.2    Bacon, P.A.3
  • 9
    • 0028023462 scopus 로고
    • Lymphocyte life-span and memory
    • Sprent, J. & Tough, D.F. Lymphocyte life-span and memory. Science 265, 1395-1400 (1994).
    • (1994) Science , vol.265 , pp. 1395-1400
    • Sprent, J.1    Tough, D.F.2
  • 10
    • 0028267677 scopus 로고
    • Turnover of naive- And memory-phenotype T cells
    • Tough, D.F. & Sprent, J. Turnover of naive- and memory-phenotype T cells. J. Exp. Med. 179, 1127-1135 (1994).
    • (1994) J. Exp. Med. , vol.179 , pp. 1127-1135
    • Tough, D.F.1    Sprent, J.2
  • 11
    • 0026812530 scopus 로고
    • Functional analysis of human T cell subsets defined by CD45 isoform expression
    • Beverley, P.C. Functional analysis of human T cell subsets defined by CD45 isoform expression. Semin. Immunol. 4, 35-41 (1992).
    • (1992) Semin. Immunol. , vol.4 , pp. 35-41
    • Beverley, P.C.1
  • 12
    • 0029008045 scopus 로고
    • In vivo estimates of division and death rates of human T lymphocytes
    • Mclean, A.R. & Michie, C.A. In vivo estimates of division and death rates of human T lymphocytes. Proc. Natl. Acad. Sci. USA 92, 3707-3711 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3707-3711
    • Mclean, A.R.1    Michie, C.A.2
  • 13
    • 0028346560 scopus 로고
    • CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
    • Trowbridge, I.S. & Thomas, M.L. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12, 85-116 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 85-116
    • Trowbridge, I.S.1    Thomas, M.L.2
  • 14
    • 0027275945 scopus 로고
    • Lifespans of naive, memory and effector lymphocytes
    • Sprent, J. Lifespans of naive, memory and effector lymphocytes. Curr. Opin. Immunol. 5, 433-138 (1993).
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 433-1138
    • Sprent, J.1
  • 15
    • 0028812436 scopus 로고
    • Age, thymopoiesis, and CD4* T-lymphocyte regeneration after intensive chemotherapy
    • Mackall, C.L. et al. Age, thymopoiesis, and CD4* T-lymphocyte regeneration after intensive chemotherapy. N. Engl. J. Med. 332, 143-149 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 143-149
    • Mackall, C.L.1
  • 16
    • 0025841704 scopus 로고
    • Kinetics of recovery of CD4* T cells in peripheral blood of deoxycoformycin-treated patients
    • Steis, R.G. et al. Kinetics of recovery of CD4* T cells in peripheral blood of deoxycoformycin-treated patients. J. Natl. Cancer Inst. 83, 1678-1679 (1991).
    • (1991) J. Natl. Cancer Inst. , vol.83 , pp. 1678-1679
    • Steis, R.G.1
  • 17
    • 0028041267 scopus 로고
    • Oligoclonality of tumor-infiltrating lymphocytes from human melanomas
    • Puisieux, I. et al. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. J. Immunol. 153, 2807-2818 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 2807-2818
    • Puisieux, I.1
  • 18
    • 0026052716 scopus 로고
    • T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type
    • Gulwani-Akolkar, B. et al. T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type. J. Exp. Med. 174, 1139-1146 (1991).
    • (1991) J. Exp. Med. , vol.174 , pp. 1139-1146
    • Gulwani-Akolkar, B.1
  • 19
    • 0028169415 scopus 로고
    • β T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice
    • β T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice. J. Exp. Med. 180, 861-872 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 861-872
    • Cibotti, R.1
  • 20
    • 0026793582 scopus 로고
    • Molecular detection and in vivo analysis of the specific T cell response to a protein antigen
    • Cochet, M. et al. Molecular detection and in vivo analysis of the specific T cell response to a protein antigen, Eur. J. Immunol. 22, 2639-2647 (1992).
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2639-2647
    • Cochet, M.1
  • 21
    • 0013610170 scopus 로고    scopus 로고
    • Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
    • Kovacs, J.A. et al. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. N. Engl. J. Med. 335, 1350-1356 (1996).
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1350-1356
    • Kovacs, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.