Removal of primate xenoreactive natural antibodies by extracorporeal perfusion of pig kidneys and livers

Transplant Immunology

Volumn 6, Issue 1, 1998, Pages 13-22

  Azimzadeh, Agnès ^a,d   Meyer, Carole ^a   Watier, Hervé ^b   Beller, Jean Paul ^a   Chenard Neu, Marie Pierre ^c   Kieny, René ^a   Boudjema, Karim ^a   Jaeck, Daniel ^a   Cinqualbre, Jacques ^a   Wolf, Philippe ^a  

^a Laboratoire de Chirurgie Experimentale   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c HÔPITAL DE HAUTEPIERRE   (France)

^d Fondation Transplantation   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COMPLEMENT; HEMOGLOBIN; PLASMA PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DILUTION; EXTRACORPOREAL CIRCULATION; HEMODYNAMICS; KIDNEY GRAFT; KIDNEY GRAFT REJECTION; KIDNEY PERFUSION; LIVER PERFUSION; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; SWINE; THROMBOCYTE COUNT; XENOTRANSPLANTATION;

EID: 0032029920     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(98)80030-0     Document Type: Article

References (54)

1. Platt JL, Vercellotti GM, Dalmasso P, et al. Transplantation of discordant xenografts: a review of progress. Immunol Today. 11:1990;450-458.
2. Bach FH, Robson SC, Winkler H, et al. Barriers to xenotransplantation. Nature Med. 1:1995;869-873.
3. Fischel RJ, Matas AJ, Perry E, Dalmasso AP, Noreen HJ, Bolman RM III. Plasma exchange, organ perfusion, and immunosuppression reduce 'natural' antibody levels as measured by binding to xeno geneic endothelial cells and prolong discordant xenograft survival. Transplant Proc. 24:1992;574-575.
4. Alexandre G, Heinle JS, Ibrahim S, Rudolph AR, Baldwin WM, Sanfilippo F. Plasmapheresis and splenectomy in experimental renal xenotransplantation. Hardy MA. Xenografts. 1989;259-266 Elsevier, New York.
5. Henry ML, Han LK, Davies EA, Orosz CG, Sedmark DD, Ferguson RM. The role of organ perfusion in xenotransplantation: influence of ex vivo xenoantibody adsorption on xenograft survival. Hardy MA. Xenograft. 1989;249-257 Elsevier, New York.
6. Fischel RJ, Matas AJ, Platt JL, et al. Cardiac xenografting in the pig-to-rhesus monkey model: manipulation of antiendothelial antibody prolongs survival. J Heart Lung Transplant. 11:1992;965-974.
7. Cooper DKC, Human PA, Lexer G, et al. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in baboon. J Heart Transplant. 7:1988;238-346.
8. Sablinski T, Latinne D, Giannello P, et al. Xenotransplantation of pig kidneys to nonhuman primates: I. Development of the model. Xenotransplantation. 2:1995;264-270.
9. Leventhal JR, John R, Fryer JP, et al. Removal of baboon and human antiporcine IgG and IgM natural antibodies by immunoadsorption. Transplantation. 59:1995;294-300.
10. Kroshus TJ, Bolman RM III, Dalmasso AP. Selective IgM depletion prolongs organ survival in an ex-vivo model of pig-to-human xenotransplantation. Transplantation. 62:1996;5-12.
11. Rydberg L, Hallberg E, Björck S, et al. Studies on the removal of anti-pig xenoantibodies in the human by plasmapheresis/immuno-adsorption. Xenotransplantation. 2:1995;253-263.
12. Taniguchi S, Neethling FA, Korchagina EY, et al. In vivo immuno-adsorption of antipig antibodies in baboons using a specific gal α1-3gal column. Transplantation. 62:1996;1379-1384.
13. Li SF, Neethling FA, Taniguchi S, et al. Glycans derived from porcine stomach mucin are effective inhibitors of natural anti-α-galactosyl antibodies in vitro and after intravenous infusion in baboons. Transplantation. 62:1996;1324-1331.
14. Liu JN, Qian YJ, Holgersson J. Removal of xenoreactive human anti-pig antibodies by absorption on recombinant mucin-containing glycoproteins carrying the gal α 1,3gal epitope. Transplantation. 63:1997;1673-1682.
15. Meyer C, Romain N, Ravanat C, et al. Porcine kidney grafts with von Willebrand disease transplanted in baboons [Abstract]. The 4th International Congress for Xenotransplantation. 7-11 September 1977.
16. Powelson J, Cosimi AB, Austen W Jr, et al. Porcine-to-primate orthotopic liver transplantation. Transplant Proc. 26:1994;1353-1354.
17. Collins BH, Chari RS, Magee JC, et al. Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure. Transplantation. 58:1994;1162-1171.
18. Geller RL, Rubinstein P, Platt JL. Variation in expression of porcine xenogeneic antigens. Transplantation. 58:1994;272-277.
19. Yoshioka H, McCalmon RT, Putnam CW, McIntosh RM, Terman DS. Attenuation of hyperacute xenograft rejection in unmodified host by extracorporeal plasma perfusion. Transplantation. 24:1977;78-80.
20. Beaufigeau M, Wolf P, Azimzadeh A, et al. Perfusion extra corporelle de foie de porc. Annales de Chirurgie. 49:1995;442.
21. Slapak M, Greenbaum M, Bardawil W, Saravis C, Joison J, McDermott WV Jr. Effect of heparin, arvin, liver perfusion, and heterologous antiplatelet serum on rejection of pig kidney by dog. Transplant Proc. 3:1971;558-561.
22. Ryan US, Maxwell G. Isolation, culture, and subculture of bovine pulmonary artery endothelial cells: mechanical methods. J Tissue Cult Methods. 10:1986;3-5.
23. Voyta JC, Via DP, Butterfield CE, Zetter BR. Identification and isolation of endothelial cells based on their increased uptake of acetyllated-low density lipoprotein. J Cell Biol. 99:1984;2034-2040.
24. Watier H, Vallée I, Thibault G, et al. Effect of human inflammatory cytokines on porcine endothelial cell MHC molecule expression: unique role for TNFα in MHC class II induction. Transplant Proc. 26:1994;1152-1155.
25. Platt JL, Turman MA, Noreen HJ, Fischel rJ, Bolman RM III, Bach FH. An ELISA assay for xenoreactive natural antibodies. Transplantation. 49:1989;1000-1001.
26. 51Cr release. Anal Cell Pathol. 10:1996;183.
27. Azimzadeh A, Lucchiari N, Beller JP, Cinqualbre J, Wolf P. Operational value for xenogeneic antibody titers on porcine endothelial and blood cells. Proceedings of the 4th Basic Sciences Symposium of the Transplantation Society. 1995;339-342.
28. Watier H, Guillaumin J, Vallée I, et al. Human NK cell-mediated direct and IgG-dependent cytotoxicity against xenogeneic porcine endothelial cells. Transplant Immunol. 4:1996;293-299.
29. Alvarado CG, Cotterell AH, Mc Curry KR, et al. Variation in the level of xenoantigen expression in porcine organs. Transplantation. 59:1995;1589-1596.
30. Watier H, Guillaumin J, Piller F, et al. Removal of terminal α-galactosyl residues form xenogeneic porcine endothelial cells. Transplantation. 62:1996;105-113.
31. Tuso PJ, Cramer DV, Yasunaga C, Cosenza CA, Wu GD, Makowka L. Removal of natural human xenoantibodies to pig vascular endothelium by perfusion of blood through pig kidneys and livers. Transplantation. 55:1993;1375-1378.
32. Kujundzic M, Koren R, Neethling FA, et al. Variability of anti-α Gal antibodies in human serum and their relation to serum cytotoxicity against pig cells. Xenotransplantation. 1:1994;58-65.
33. Hennessy VL, Hicks RE, Niewiarowski S, Edmunds LH, Colman RW. Function of human platelets during extracorporeal circulation. Am J Physiol. 232:1995;H622.
34. Brewer RJ, Del Rio MJ, Roslin MS, et al. Depletion of preformed antibody in primates for discordant xenotransplantation by continuous donor organ plasma perfusion. Transplant Proc. 25:1993;385-386.
35. Henry ML, Han LK, Davies EA, Sedmak DD, Ferguson RM. Antibody depletion prolongs xenograft survival. Surgery. 115:1994;355-361.
36. Vanhove B, Bach FH. Human xenoreactive natural antibodies avidity and targets on porcine endothelial cells. Transplantation. 56:1993;1251-1253.
37. Parker W, Bruno D, Holzknecht ZE, Platt JL. Characterization and affinity isolation of xenoreactive human natural antibodies. J Immunol. 153:1994;3791-3803.
38. Platt JL, Dalmasso AP, Lindman BJ, Ihrcke NS, Bach FH. The role of C5a and antibody in the release of heparan sulfate from endothelial cells. Eur J Immunol. 21:1991;2887-2890.
39. Welsh KI, Taube DH, Thick M, Palmer A, Stevens N, Binns RM, White DJG. Human antibodies to pig determinants and their association with hyperacute rejection of xenografts. Cooper DKC, Kemp E, Reemtsma K. Xenotransplantation. 1991;501-510 Springer, Berlin.
40. Möller E, Möller G. Quantitative studies of the sensitivity of normal and neoplastic mouse cells to the cytotoxic action of isoantibodies. J Exp Med. 115:1962;527-553.
41. Tuso PJ, Cramer DV, Middleton YD, et al. Pig aortic endothelial cell antigens recognized by human IgM natural antibodies. Transplantation. 56:1993;651-655.
42. Schaapherder AFM, Daha MR, Bulte MJW, Van Der Woude FJ, Gooszen HG. Antibody-dependent cell-mediated cytotoxicity against porcine endothelium induced by a majority of human sera. Transplantation. 57:1994;1376-1382.
43. Inverardi L, Pardi R. Early events in cell-mediated recognition of vascularized xenografts: cooperative interactions between selected lymphocyte subsets and natural antibodies. Immunol Rev. 141:1994;71-94.
44. Galili U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans. Immunol Today. 14:1993;480-482.
45. Chan DV, Auchincloss H. Human anti-pig cell-mediated cytotoxicity in vitro involves non-T as well as T cell components. Xeno-transplantation. 3:1996;158-165.
46. Moberg AW, Shons AR, Gewurz H, Mozes M, Najarian JS. Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation and antibody synthesis. Transplant Proc. 3:1971;538-541.
47. Kroshus TJ, Dalmasso AP, Leventhal JR, John R, Matas AJ, Bolman RJ III. Antibody removal of column immunoabsorption prevents tissue injury in an exo vivo model of pig-to-human xenograft hyperacute rejection. J Surg Res. 59:1995;43-50.
48. Makowka L, Wu GD, Hoffman A, et al. Immunohistopathologic lesions associated with the rejection of a pig-to-human xenograft. Transplant Proc. 26:1994;1074-1075.
49. Tector AJ, Elias N, Rosenberg L, et al. Mechanisms of resistance to injury in pig livers perfused with blood from patients in liver failure. Transplant Proc. 29:1997;966-969.
50. Satake M, Kumagai-Braesch M, Kawagishi N, Tibell A, Groth CG, Möller E. Kinetics and character of xenoantibody formation in diabetic patients transplanted with fetal porcine islet cell clusters. Xenotransplantation. 1:1994;24-35.
51. Cotterell AH, Collins BH, Parker W, Harland RC, Platt JL. The humoral immune response in humans following cross-perfusion of porcine organs. Transplantation. 60:1995;861-868.
52. Hamilton KK, Hattori R, Esmon CT, Sims PJ. Complement proteins C5b-9 induced vesiculation of the endothelial plasma membrane and expose catalytic surface for assembly of the prothrombinase enzyme complex. J Biol Chem. 265:1990;3809-3814.
53. Baldwin WM III, Pruitt SK, Brauer RB, Daha MR, Sanfilippo F. Complement in organ transplantation. Transplantation. 59:1995;797-808.
54. Bach FH, Blakely ML, Van Der Werf M, et al. Discordant xenografting: a working model of problems and issues. Xeno. 1:1993;8-16.