Evidence of human non-α-galactosyl antibodies involved in the hyperacute rejection of pig lungs and their removal by pig organ perfusion

Journal of Thoracic and Cardiovascular Surgery

Volumn 116, Issue 5, 1998, Pages 831-843

  Macchiarini, P ^a   Oriol, R ^a   Azimzadeh, A ^a   De Montpreville, V ^a   Rieben, R ^a   Bovin, N ^a   Mazmanian, M ^a   Dartevelle, P ^a   Sugarbaker, D J ^a   Salerno, C T ^a  

^a CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BLOOD CLOTTING FACTOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; GALACTOSE; IMMUNOGLOBULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; EXPERIMENTAL TRANSPLANTATION; GRAFT REJECTION; GRAFT SURVIVAL; HEMOLYSIS; HISTOPATHOLOGY; HUMAN; IMMUNOADSORPTION; LUNG PERFUSION; LUNG TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; SWINE; XENOTRANSPLANTATION;

EID: 18244419906     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(98)00447-4     Document Type: Article

References (30)

1. JL Platt GM Vercelotti AP Dalmasso Transplantation of discordant xenografts: A review of progress Immunol Today 11 1990 450 456
2. RN Pierson W Kasper-Konig DN Tew VK Young JJ Dunning J Horsley Hyperacute lung rejection in a pig-to-human transplant model Transplantation 63 1997 594 603
3. P Macchiarini GM Mazmanian R Oriol Ex-vivo lung model of pig to human hyperacute xenograft rejection J Thorac Cardiovasc Surg 114 1997 315 325
4. CW Daggett M Yeatman AJ Lodge EP Chen VP Trigt GW Byrne Swine lungs expressing human complement-regulatory proteins are protected against pulmonary dysfunction in a human plasma perfusion model J Thorac Cardiovasc Surg 113 1997 390 398
5. CW Hoopes JL Platt Molecular strategies for clinical xenotransplantation in cardiothoracic surgery Semin Thorac Cardiovasc Surg 8 1996 156 174
6. JL Platt RJ Fischel AJ Matas SA Reif RM Bolman FH Bach Immunopathology of hyperacute xenograft rejection in a swine-to-primate model Transplantation 52 1991 214 220
7. CW Daggett M Yeatman AJ Lodge EP Chen SS Linn C Gullotto Total respiratory support from swine lungs in primate recipients J Thorac Cardiovasc Surg 115 1998 19 27
8. RN Pierson G Pino-Chavez VK Young W Kaspar-Konig DK White J Wallwork Expression of human decay accelerating factor may protect pig lung from hyperacute rejection by human blood J Heart Lung Tranplant 16 1997 231 239
9. RN Pierson 3d W Kaspar-König DN Tew VK Young PC Braidley DJ White Profound pulmonary hypertension characteristic of pig lung rejection by blood is mediated by xenoreactive antibodies independent of complement Transplant Proc 27 1995 274
10. P Macchiarini R Oriol M Mazmanian P Dartevelle Lung xenotransplantation: lessons learned and future perspectives KL Franco JB Putman Advances in thoracic surgery 1998 BC Decker Hamilton, Ontario 404 414
11. EY Korchagina NV Bovin Synthesis of spacered trisaccharides with blood group specificities A and B, their fragments and structural analogs Bioorg Khim 18 1992 283 298
12. N Bovin E Korchagina T Zemlyanukhina N Byramova O Galanina A Zemlyakov Synthesis of polymeric neoglycoconjugates based on N -substituted polyacrylamide Glycoconjugate J 10 1993 142 151
13. NV Bovin Sugar-polyacrylamide conjugates as probes for cell lectins HJ Gabius S Gabius Lectins and glycobiology 1993 Springer-Verlag Berlin 23 31
14. U. Galili Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation Immunol Today 14 1993 480 482
15. R Rieben E van Allmen EY Korchagina UE Nydegger FA Neethling M Kujundzic Detection, immunoabsorption, and inhibition of cytotoxic activity of anti-αGal antibodies using newly developed substances with synthetic Galα1-3Gal disaccharide epitopes Xenotransplantation 2 1995 98 106
16. A Azimzadeh K Wolf D Thibaudeau J Cinqualbre JP Soulillou I Anegon Comparative study of target antigens for primate xenoreactive natural antibodies in pig and rat endothelial cells Transplantation 64 1997 1166 1174
17. MS Sandrin HA Vaughan PL Dabrowski IF. McKenzie Anti-pig antibodies in human serum react predominantly with Galα(1,3)Gal epitopes Proc Natl Acad Sci U S A 90 1993 11391 11395
18. AH Good DK Cooper AJ Malcolm E Ippolito E Koren FA Neethling Identification of carbohydrate structures that bind human anti-porcine antibodies: implications for discordant xenografting in humans Transplant Proc 24 1992 559 562
19. R Oriol Y Ye E Koren DK Cooper Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation Transplantation 56 1993 1433 1442
20. W Parker D Bruno ZE Holzknecht JL Platt Characterization and affinity isolation of xenoreactive human natural antibodies J Immunol 153 1994 3791 3803
21. GP Alexandre P Gianello D Latinne M Carlier A Dewalle L Von Obbergh Plasmapheresis and splenectomy in experimental renal xenotransplantation MA Hardy Xenografts 25 1989 Elsevier Science New York 259 266
22. A Palmer K Welsh P Gjorstrup M Bewick M Thick Removal of anti-HLA antibodies by extracorporeal immunoabsorption to enable renal transplantation Lancet 1 1989 10 12
23. AH Cotterell BH Collins W Parker RC Harland JL Platt The humoral immune response in humans following cross-perfusion of porcine organs Transplantation 60 1995 861 868
24. RS Chari BH Collins JC Mages JC DiMaio AD Kirk RC Harland Brief report: treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation N Engl J Med 331 1994 234 237
25. A Azimzadeh C Meyer H Waiter JP Beller MP Chenard-Neu R Kieny Removal of primate xenoreactive natural antibodies by extracorporeal perfusion of pig kidneys and livers Transplant Immunol 6 1998 13 22
26. L Rydberg S Bjorck E Hallberg S Magnusson S Sumitran BE Samuelsson Extracorporeal (“ex vivo”) connection of pig kidneys to humans. II. The anti-pig antibody response Xenotransplantation 3 1996 340 353
27. Y Xu T Sablinski P Gianello M Bailin R Monroy T Kozlowski Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by Galα1-3Gal b 1-4 b Glc-X immunoaffinity column Transplantation 65 1998 172 179
28. KI Welsh DH Taube M Thick A Palmer N Stevens RM Binns Human antibodies to pig determinants and their association with hyperacute rejection of xenografts DK Cooper E Kemp K Reemtsma DJ White Xenotransplantation 1991 Springer Berlin 501 510
29. SP Cooke J Hederer D Pearson CO Savage Characterization of human IgG-binding xenoantigens expressed by porcine aortic endothelial cells Transplantation 60 1995 1274 1284
30. N Atia L Camoin G Duflos C Chereau B Malassagne F Filipponi Porcine serotransferrin: a major xenoantigen recognized by human natural IgG Proceedings of the 4th International Congress for Xenotransplantation. Nantes 1997 abstract 076