Intravenous synthetic αgal saccharides delay hyperacute rejection following pig-to-baboon heart transplantation

Xenotransplantation

Volumn 6, Issue 1, 1999, Pages 36-42

  Romano, Egidio ^a,b,f   Neethling, Francisca A ^c   Nilsson, Kurt ^d   Kosanke, Stanley ^e   Shimizu, Akira ^c   Magnusson, Stefan ^b   Svensson, Lola ^b   Samuelsson, Bo ^b   Cooper, David K C ^c  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Glycorex AB   (Sweden)

^e UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^f NONE   (Venezuela)

Author keywords

Anti Gal antibodies; Heart; Hyperacute rejection; Pig to baboon; Synthetic oligosaccharides; Xenotransplantation

Indexed keywords

GALACTOSE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; OLIGOSACCHARIDE; ALPHA GALACTOSYL EPITOPE; ALPHA-GALACTOSYL EPITOPE; DISACCHARIDE; GALACTOSYL (1 3)GALACTOSE; GALACTOSYL-(1-3)GALACTOSE; HETEROPHILE ANTIBODY; TRISACCHARIDE;

ADOLESCENT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BABOON; BLOOD GROUP ABO INCOMPATIBILITY; BLOOD LEVEL; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EXCRETION; DRUG HALF LIFE; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HEMAGGLUTINATION; HEMOLYSIS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; SWINE; URINE LEVEL; XENOTRANSPLANTATION; ACUTE DISEASE; ANIMAL; BLOOD; ERYTHROCYTE; IMMUNOLOGY; PAPIO; PATHOLOGY; SAFETY; XENOGRAFT;

ACUTE DISEASE; ANIMALS; ANTIBODIES, HETEROPHILE; DISACCHARIDES; ERYTHROCYTES; GRAFT REJECTION; HEART TRANSPLANTATION; HEMAGGLUTINATION; HEMOLYSIS; OLIGOSACCHARIDES; PAPIO; SAFETY; SWINE; TRANSPLANTATION, HETEROLOGOUS; TRISACCHARIDES;

EID: 0032587273     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3089.1999.00005.x     Document Type: Article

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