Control of cell migration during Caenorhabditis elegans development

Current Opinion in Cell Biology

Volumn 11, Issue 5, 1999, Pages 608-613

  Blelloch, Robert ^a   Newman, Craig ^a   Kimble, Judith ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE; METALLOPROTEINASE; NETRIN;

CAENORHABDITIS ELEGANS; CELL MIGRATION; DEVELOPMENT; EMBRYO AXIS; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS;

EID: 0032870777     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(99)00028-9     Document Type: Review

References (54)

1. Antebi A, Norris CR, Hedgecock EM, Garriga G Cell and growth cone migrations. Riddle DL, Blumenthal T, Meyer BJ, Priess JR C. elegans II. 1997;583-609 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
2. Montell DJ The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development. Development. 126:1999;3035-3046.
3. Brenner S The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
4. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science. 282:1998;2012-2018. This paper describes the completion of the C. elegans genome sequence and its implications.
5. Guo S, Kemphues KJ par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell. 81:1995;611-620.
6. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391:1998;806-811. This paper describes the use of exogenously applied double-stranded RNA to inhibit gene function.
7. Chen EB, Stern MJ Understanding cell migration guidance: lessons from sex myoblast migration in C. elegans. Trends Genetics. 14:1998;322-327.
8. Metzger RJ, Krasnow MA Genetic control of branching morphogenesis. Science. 284:1999;1635-1639.
9. Hogan BLM Morphogenesis. Cell. 96:1999;225-233.
10. Burdine RD, Chen EB, Kwok SF, Stern MJ egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans. Proc Natl Acad Sci USA. 94:1997;2433-2437.
11. DeVore DL, Horvitz HR, Stern MJ An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites. Cell. 83:1995;611-620.
12. Burdine RD, Branda CS, Stern MJ EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. Development. 125:1998;1083-1093. This paper describes two sources of EGL-17/FGF for controlling SM migration, vulval cells and somatic gonadal cells. In addition, EGL-17 is shown to play an instructive role in the migration of the sex myoblasts.
13. Kokel M, Borland CZ, DeLong L, Horvitz HR, Stern MJ clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans. Genes Dev. 12:1998;1425-1437.
14. McGinnis W, Krumlauf R Homeobox genes and axial patterning. Cell. 68:1992;283-302.
15. Salser SJ, Kenyon C Patterning C. elegans: homeotic cluster genes, cell fates and cell migrations. Trends Genetics. 10:1994;159-164.
16. Studer M, Lumsden A, Ariza-McNaughton L, Bradley A, Krumlauf R Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1. Nature. 384:1996;630-634.
17. Sym M, Robinson N, Kenyon C MIG-13 positions migrating cells along the anteroposterior body axis of C. elegans. Cell. 98:1999;25-36. This paper identifies MIG-13, a component of the global anterior-posterior guidance system that acts non-autonomously. The level of MIG-13 protein is proposed to regulate the final positions of migrating cells.
18. Salser SJ, Kenyon C Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of migration. Nature. 355:1992;255-258.
19. Harris J, Honigberg L, Robinson N, Kenyon C Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position. Development. 122:1996;3117-3131.
20. Clark SG, Chisholm AD, Horvitz HR Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39. Cell. 74:1993;43-55.
21. Wang BB, Muller-Immergluck MM, Austin J, Robinson NT, Chisholm A, Kenyon C A homeotic gene cluster patterns the anteroposterior body axis of C. elegans. Cell. 74:1993;29-42.
22. Sulston JE, Schierenberg E, White JG, Thomson JN The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol. 100:1983;64-119.
23. Maloof JN, Shangbo J, Harris JM, Jongeward GD, Kenyon C A Wnt signaling pathway controls Hox gene expression and neuroblast migration in C. elegans. Development. 126:1999;37-49. The authors show that mab-5 expression in the QL neuroblast depends on Wnt signaling.
24. Hedgecock EM, Culotti JG, Hall DH The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron. 2:1990;61-85.
25. Culotti JG, Merz DC DCC and netrins. Curr Opin Cell Biol. 10:1998;609-613.
26. Serafini T, Kennedy TE, Galko MJ, Mirzayan C, Jessell TM, Tessier-Lavigne M The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell. 78:1994;409-424.
27. Ishii N, Wadsworth WG, Stern BD, Culotti JG, Hedgecock EM UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans. Neuron. 9:1992;873-881.
28. Wadsworth WG, Bhatt H, Hedgecock EM Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron. 16:1996;35-46.
29. Leung-Hagesteijn C, Spence AM, Stern BD, Zhou Y, Su M-W, Hedgecock EM, Culotti JG UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Cell. 71:1992;289-299.
30. Chan SS-Y, Zheng H, Su M-W, Wilk R, Killeen MT, Hedgecock EM, Culotti JG UNC-40, a C. elegans homolog of DCC (deleted in colorectal cancer), is required in motile cells responding to UNC-6 netrin cues. Cell. 87:1996;187-195.
31. Bashaw GJ, Goodman CS Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion. Cell. 97:1999;917-926. The Drosophila ventral midline expresses both attractive and repulsive migrational cues. By engineering chimeric receptor molecules, the authors show that attraction versus repulsion is mediated by the intracellular domains of the receptors.
32. Hong K, Hinck L, Nishiyama M, Poo M-m, Tessier-Lavigne M, Stein E A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell. 97:1999;927-941. This paper examines the roles of UNC-5 and UNC-40 like receptors in mediating the attractive and repulsive activities of netrin. They present evidence that the cytoplasmic domains of these two receptors are able to physically interact with one another and that presence of the UNC-5 cytoplasmic region is sufficient to convert attractive behavior into repulsive behavior.
33. Colavita A, Culotti JG Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans. Dev Biol. 194:1998;72-85.
34. Colavita A, Krishna S, Zheng H, Padgett RW, Culotti JG Pioneer axon guidance by UNC-129, a C. elegans TGF-β Science. 281:1998;706-709. A member of the TGFβ family of growth factors is shown to play a role in the dorsal directed movement of cells and axons. Normally expressed dorsally, ectopic expression of unc-129 in ventral muscle results in defects in the dorsal migration of gonadal leader cells.
35. Vincent S, Ruberte E, Grieder NC, Chen C-K, Haerry T, Schuh R, Affolter M DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo. Development. 124:1997;2741-2750.
36. Wightman B, Clark SG, Taskar AM, Forrester WC, Maricq AV, Bargmann CI, Garriga G The C. elegans gene vab-8 guides posteriorly directed axon outgrowth and cell migration. Development. 122:1996;671-682.
37. Wolf FW, Hung M-S, Wightman B, Way J, Garriga G vab-8 is a key regulator of posteriorly directed migrations in C. elegans and encodes a novel protein with kinesin motor similarity. Neuron. 20:1998;655-666. This paper shows that vab-8, a gene postulated to be part of a global anterior-posterior guidance system, encodes an intracellular protein with distant homology to kinesin.
38. Hall A Rho GTPases and the actin cytoskeleton. Science. 279:1998;509-514.
39. Zipkin ID, Kindt RM, Kenyon CJ Role of a new Rho family member in cell migration and axon guidance in C. elegans. Cell. 90:1997;883-894.
40. Luo L, Liao YJ, Jan LY, Jan YN Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8:1994;1787-1802.
41. Murphy AM, Montell DJ Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis. J Cell Biol. 133:1996;617-630.
42. Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, Jan YN Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines. Nature. 379:1996;837-840.
43. Steven R, Kubiseski TJ, Zheng H, Kulkarni S, Mancillas J, Ruiz Morales A, Hogue CWV, Pawson T, Culotti J UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans. Cell. 92:1998;785-795. Cloning of unc-73 reveals that it encodes a Rac specific guanine nucleotide exchange factor, reinforcing the role of small G proteins in the mechanics of cell migration.
44. Wu YC, Horvitz HR C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature. 392:1998;501-504. The ced-5 gene is required for both phagocytosis and gonadal leader cell migration. The identification of CED-5 as a homolog of human DOCK180 could provide a key link between extracellular signaling and modulation of cytoskeleton via the Rac protein.
45. Hasegawa H, Kiyokawa E, Tanaka S, Nagashima K, Gotoh N, Shibuya M, Kurata T, Matsuda M DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol. 16:1996;1770-1776.
46. Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA CAS/Crk coupling serves as a 'molecular switch' for induction of cell migration. J Cell Biol. 140:1998;961-972.
47. Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev. 12:1998;3337-3342.
48. Kiyokawa E, Hashimoto Y, Kobayashi S, Sugimura H, Kurata T, Matsuda M Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev. 12:1998;3331-3336.
49. Shapiro SD Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Curr Opin Cell Biol. 10:1998;602-608.
50. Blelloch R, Anna-Arriola SS, Gao D, Li Y, Hodgkin J, Kimble J: The gon-1 gene is required for morphogenesis of the C. elegans gonad. Dev Biol 1999, in press. This work shows that gon-1 is required for cell migration of the gonadal leader cell and for gonadal morphogenesis. Most migration regulators affect where or when a cell migrates, but gon-1 gene controls whether or not the leader cell migrates.
51. Blelloch R, Kimble J Control of organ shape by a secreted metalloprotease in the nematode C. elegans. Nature. 399:1999;586-590. This paper reports that, gon-1 encodes a secreted metalloprotease and demonstrates that the site of gon-1 expression influences gonadal shape.
52. Nishiwaki K Mutations affecting symmetrical migration of distal tip cells in Caenorhabditis elegans. Genetics. 152:1999;985-997.
53. Colige A, Li S-W, Sieron AL, Nusgens BV, Prockop DJ, Lapière CM cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components. Proc Natl Acad Sci USA. 94:1997;2374-2379.
54. Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, Rosenfeld SA, Copeland RA, Decicco CP, Wynn R Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science. 284:1999;1664-1666.