Differential temporal expression of mRNAs for ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), and their receptors (CNTFR α, LIFRβ, IL-6R α and gp130) in injured peripheral nerves

Brain Research

Volumn 793, Issue 1-2, 1998, Pages 321-327

  Ito, Yasuhiro ^a   Yamamoto, Masahiko ^a   Li, Mei ^a,b   Doyu, Manabu ^a   Tanaka, Fumiaki ^a   Mutch, Tatsuro ^c   Mitsuma, Terunori ^b   Sobue, Gen ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AICHI MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

Author keywords

Ciliary neurotrophic factor; Interleukin 6; Leukemia inhibitory factor; mRNA expression; Nerve injury; Receptor

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; GLYCOPROTEIN GP 130; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD; CILIARY NEUROTROPHIC FACTOR; CYTOKINE RECEPTOR GP130; DISEASE MODELS, ANIMAL; GROWTH INHIBITORS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT; LYMPHOKINES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED STRAINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; PERIPHERAL NERVOUS SYSTEM DISEASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, CYTOKINE; RECEPTORS, INTERLEUKIN-6; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, OSM-LIF; RNA, MESSENGER;

EID: 0032543111     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00242-X     Document Type: Article

References (38)

1. L.R. Banner, P.H. Patterson, Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia, Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 7109-7113.
2. M. Barbacid, Neurotrophic factors and their receptors, Curr. Opin. Cell. Biol. 7 (1995) 148-155.
3. J. Bauer, T.M. Bauer, T. Kalb, T. Taga, G. Lengyel, T. Hirano, T. Kishimoto, G. Acs, L. Mayer, W. Gerok, Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes, J. Exp. Med. 170 (1989) 1537-1549.
4. J.F. Bazan, Neuropoietic cytokines in the hematopoietic fold, Neuron 7 (1991) 197-208.
5. L.M. Bolin, A.N. Verity, J.E. Silver, E.M. Shooter, J.S. Abrams, Interleukin-6 production by Schwann cells and induction in Sciatic nerve injury, J. Neurochem. 64 (1995) 850-858.
6. R. Curtis, S.S. Scherer, R. Somogyi, K.M. Adryan, N.Y. Ip, Y. Zhu, R.M. Lindsay, P.S. DiStefano, Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve, Neuron 12 (1994) 191-204.
7. R. Curtis, K.M. Adryan, Y. Zhu, P.J. Harkness, R.M. Lindsay, P.S. DiStefano, Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury, Nature 365 (1993) 253-255.
8. S. Davis, T.H. Aldlich, N. Stahl, L. Pan, T. Taga, T. Kishimoto, N.Y. Ip, G.D. Yancopoulos, LIFRβ and gp130 as heterodimerizing signal transducers of tripartite CNTF receptor, Science 260 (1993) 1805-1808.
9. S. Davis, T.H. Aldlich, D.M. Valenzuela, V. Wong, M.E. Furth, S.P. Squinto, G.D. Yancopoulos, The receptor for ciliary neurotrophic factor, Science 253 (1991) 59-63.
10. S. Davis, T.H. Aldlich, N.Y. Ip, N. Stahl, S. Scherer, T. Farruggella, P.S. DiStefano, R. Curtis, N. Panayotatos, H. Gascan, S. Chevalier, G.D. Yancopoulos, Released form of CNTF receptor α component as a soluble mediator of CNTF responses, Science 259 (1993) 1736-1739.
11. M. Doyu, G. Sobue, E. Ken, K. Kimata, T. Shinomura, Y. Yamada, T. Mitsuma, A. Takahashi, Laminin A, B1, and B2 chain gene expression in transected and regenerating nerves: regulation by axonal signals, J. Neurochem. 60 (1993) 543-551.
12. B. Friedman, S.S. Scherer, J.S. Rudge, M. Helgren, D. Morrisey, J. McClain, D. Wang, S.J. Wiegand, M.E. Furth, R.M. Lindsay, N.Y. Ip, Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo, Neuron 9 (1992) 295-305.
13. M. Geisterfer, J. Gauldie, Regulation of signal transducer, gp130 and the LIF receptor in acute inflammation in vivo, Cytokine 8 (1996) 283-287.
14. M. Geisterfer, C. Richards, M. Baumann, G. Fey, D. Gywnne, J. Gauldie, Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo, Cytokine 5 (1993) 1-7.
15. M.L. Heaney, D.W. Golde, Soluble cytokine receptors, Blood 87 (1996) 847-857.
16. M.E. Helgren, S.P. Squinto, H.L. Davis, D.J. Parry, T.G. Boulton, C.S. Heck, Y. Zhu, G.D. Yancopoulos, R.M. Lindsay, P.S. DiStefano, Trophic effect of ciliary neurotrophic factor on denerved skeletal muscle, Cell 76 (1994) 493-504.
17. D.J. Hilton, N.A. Nicola, D. Metcalf, Distribution and comparison of receptors for leukemia inhibitory factor on murine hemopoietic and hepatic cells, J. Cell. Physiol. 146 (1991) 207-215.
18. H. Hirota, H. Kiyama, T. Kishimoto, T. Taga, Accelerated nerve regeneration in mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma, J. Exp. Med. 183 (1996) 2627-2634.
19. N.Y. Ip, S.H. Nye, T.G. Boulton, S. Davis, T. Taga, Y. Li, S.J. Birren, K. Yasukawa, T. Kishimoto, D.J. Anderson, N. Stahl, G.D. Yancopoulos, CNTF and LIF act on neural cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130, Cell 69 (1992) 1121-1132.
20. E.M. Johnson, M. Taniuchi, P.S. Distefano, Expression and possible function of nerve growth factor receptors on Schwann cells, Trends Neurosci. 11 (1988) 299-304.
21. T. Kishimoto, The biology of interleukin-6, Blood 74 (1989) 1-10.
22. J.B. Kurek, L. Austin, S.S. Cheema, P.F. Bartlett, M. Murphy, Up-regulation of leukemia inhibitory factor and interleukin-6 in transected sciatic nerve and muscle following denervation, Neuromuscular Disord. 6 (1996) 105-114.
23. D. Lindholm, R. Heumann, M. Meyer, H. Thoenen, Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve, Nature 330 (1987) 658-659.
24. M. Murphy, R. Dutton, S. Koblar, S. Cheema, P. Bartlett, Cytokines which signal through the LIF receptor and their actions in the nervous system, Prog. Neurobiol. (1997) 355-378.
25. R.W. Oppenheim, Neurotrophic survival molecules for motoneurons: an embarrassment of riches, Neuron 17 (1996) 195-197.
26. M. Otsuka, Y. Terada, T. Yang, H. Nonoguchi, K. Tomita, F. Marumo, Localization of cyclophilin A and cyclophilin C mRNA in murine kidney using RT-PCR, Kidney. Int. (1994) 1340-1345.
27. V.H. Perry, M.C. Brown, S. Gordon, The macrophage response to central and peripheral nerve injury, J. Exp. Med. 165 (1987) 1218-1223.
28. M. Saito, K. Yoshida, M. Hibi, T. Taga, T. Kishimoto, Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo, J. Immunol. 148 (1992) 4066-4071.
29. 2 zinc-finger protein with multiple consensus phosphorylation sites is conserved in mouse and human, Gene 152 (1995) 233-238.
30. H. Schooltink, H.S-V. de Leur, P.C. Heinrich, S. Rose-John, Upregulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells, FEBS Lett. 297 (1992) 263-265.
31. M. Sendtner, K.A. Stöckli, H. Thoenen, Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration, J. Cell. Biol. 118 (1992) 139-148.
32. M. Sendtner, D. Carroll, B. Holtmann, R.A. Hughes, H. Thoenen, Ciliary neurotrophic factor, J. Neurobiol. 25 (1994) 1436-1453.
33. J. Stahl, D.P. Gearing, T.A. Willson, M.A. Brown, J.A. King, N.M. Gough, Structural organization of the genes for murine and human leukemia inhibitory factor. Evolutionary conservation of coding and non-coding regions, J. Biol. Chem. 265 (1990) 8833-8841.
34. T. Sugita, T. Totsuka, M. Saito, K. Yamasaki, T. Taga, T. Hirano, T. Kishimoto, Functional murine interleukin 6 receptor with the intracisternal a particle gene product at its cytoplasmic domain, its possible role in plasmacytomagenesis, J. Exp. Med. 171 (1990) 2001-2009.
35. O. Tanabe, S. Akira, T. Kamiya, G.G. Wong, T. Hirano, T. Kishimoto, Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human, J. Immunol. 141 (1988) 3875-3881.
36. M. Tomida, Y. Yamamoto-Yamaguchi, M. Hozumi, Three different cDNAs encoding mouse D-factor/LIF receptor, J. Biochem. 115 (1994) 557-562.
37. D.M. Valenzuela, E. Rojas, M.M. LeBeau, R. Espinosa III, C.I. Brannan, J. McClain, P. Masiakowski, N.Y. Ip, N.G. Copeland, N.A. Jenkins, G.D. Yancopoulos, Genomic organization and chromosomal localization of human and mouse genes encoding the a receptor component for ciliary neurotrophic factor, Genomics 25 (1995) 157-163.
38. NGFR, TrkA, TrkB, and TrkC) in the adult human peripheral nervous system and nonneural tissues, Neurochem. Res. 21 (1996) 929-938.